Home / Other Transferase Inhibitors / MYX 1715

MYX 1715

Catalog #: 8109 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8109/5
MYX 1715 | Other Transferase Inhibitors
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Description: N-myristoyltransferase (NMT) inhibitor

Chemical Name: 4-[2-[2-[3-(2-Aminoethyl)imidazo[1,2-a]pyridin-6-yl]-5-chlorophenoxy]ethyl]-N,N,1,5-tetramethyl-1H-pyrazole-3-carboxamide dihydrochloride

Purity: ≥98%

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Biological Activity

MYX 1715 is a N-myristoyltransferase inhibitor (NMT). MYX 1715 selectively kills senescent cancer cells in mouse models of paediatric pituitary tumors and liver cancer, and prevents tumor growth in mouse xenografts. In mouse models of idiopathic pulmonary fibrosis (IPF) and NASH, MYX 1715 reduces both lung and liver fibrosis, and decreases inflammation and steatosis.

Technical Data

M.Wt:
553.91
Formula:
C25H29ClN6O2.2HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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