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N6-Cyclopentyladenosine

Catalog #: 1702
12 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1702/50
N6-Cyclopentyladenosine | CAS No. 41552-82-3 | Adenosine A1 Receptor Agonists
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Description: Potent and selective A1 agonist
Alternative Names: CPA

Chemical Name: N-Cyclopentyladenosine

Purity: ≥99%

Product Details
Citations (12)
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Biological Activity

N6-Cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for hA2B). Centrally active following systemic administration in vivo.

Technical Data

M.Wt:
335.36
Formula:
C15H21N5O4
Solubility:
Soluble to 100 mM in 1eq. HCl
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
41552-82-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for N6-Cyclopentyladenosine

The citations listed below are publications that use Tocris products. Selected citations for N6-Cyclopentyladenosine include:

12 Citations: Showing 1 - 10

  1. Adenosine arrests breast cancer cell motility by A3 receptor stimulation.
    Authors: Ledderose Et al.
    Purinergic Signalling  2016;
  2. Role of adenosine receptor subtypes in metha. reward and reinforcement.
    Authors: Kavanagh Et al.
    PLoS One  2015;89:265
  3. Characterization of spontaneous, transient adenosine release in the caudate-putamen and prefrontal cortex.
    Authors: Nguyen Et al.
    PLoS One  2014;9:e87165
  4. Cancellation of cellular responses to nanoelectroporation by reversing the stimulus polarity.
    Authors: Pakhomov Et al.
    Cell Mol Life Sci  2014;71:4431
  5. Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.
    Authors: Kozma Et al.
    Biochem Pharmacol  2013;85:1171
  6. Lysosomes shape Ins(1,4,5)P3-evoked Ca2+ signals by selectively sequestering Ca2+ released from the endoplasmic reticulum.
    Authors: López-Sanjurjo Et al.
    J Cell Sci  2013;126:289
  7. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to DA D2 receptors in rats.
    Authors: Hobson Et al.
    Neuropharmacology  2012;63:1172
  8. Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses.
    Authors: Lemieux Et al.
    J Cell Biol  2012;198:1055
  9. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of δ9-tetrahydrocannabinol on spatial memory.
    Authors: Sousa Et al.
    Neuropsychopharmacology  2011;36:472
  10. Presynaptically expressed long-term potentiation increases multivesicular release at parallel fiber synapses.
    Authors: Bender Et al.
    J Neurosci  2009;29:10974

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