Nicotinamide Riboside

Catalog # Availability Size / Price Qty
6018/50
Nicotinamide Riboside | CAS No. 23111-00-4 | Enzyme Substrates
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Description: NAD+ precursor; substrate for nicotinamide riboside kinases

Chemical Name: 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium chloride

Purity: ≥98%

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Biological Activity

Nicotinamide Riboside is an NAD+ precursor. It is a substrate for nicotinamide riboside kinases (NRK1/2). Nicotinamide Riboside shows neuroprotective effects in a mouse model of type 2 diabetes and improves mitochondrial function in muscle stem cells in aged mice. The compound also corrects non-alchoholic fatty liver disease phenotype induced by NAD+ deficiency or high-fat diet in mice. Orally bioavailable.

Technical Data

M.Wt:
290.7
Formula:
C11H15ClN2O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in water
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
23111-00-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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