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Noradrenaline bitartrate

Catalog #: 5169
9 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5169/50
Noradrenaline bitartrate | CAS No. 51-40-1 | Non-selective Adrenergic alpha Receptor Agonists
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Description: Endogenous adrenergic hormone and neurotransmitter
Alternative Names: Norepinephrine

Chemical Name: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol (L-(+))-bitartrate salt

Purity: ≥99%

Product Details
Citations (9)
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Biological Activity

Noradrenaline bitartrate is an endogenous adrenergic hormone and neurotransmitter. A classical stress hormone; underlies the fight or flight response, along with adrenaline. Increases heart rate. Vasoconstrictor.

Technical Data

M.Wt:
319.26
Formula:
C8H11NO3.C4H6O6
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
51-40-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. NE in depressive reactions. A review.
    Bunney et al.
    Arch.Gen.Psychiatry., 1965;13:483
  2. Stress and brain noradrenaline: A review.
    Gary et al.
    Neuroscience & Biobehavioral Reviews, 1985;9:233
  3. NE: the next therapeutics frontier for Parkinson's disease.
    Lewitt et al.
    Transl.Neurodegener., 2012;1:4

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Citations for Noradrenaline bitartrate

The citations listed below are publications that use Tocris products. Selected citations for Noradrenaline bitartrate include:

9 Citations: Showing 1 - 9

  1. Chronic intermittent ethanol exposure disrupts stress-related tripartite communication to impact affect-related behavioral selection in male rats.
    Authors: S Et al.
    Neurobiol Stress  2023;24:100539
  2. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
    Authors: David E Et al.
    Cell  2022;185:3390-3407.e18
  3. Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice.
    Authors: Jordi Et al.
    J Neurochem  2022;160:218-233
  4. Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain.
    Authors: Xinzhong Et al.
    Neuron  2022;110:209-220.e6
  5. Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation.
    Authors: Asya Et al.
    Immunity  2021;54:1022-1036.e8
  6. Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons.
    Authors: Khaled Et al.
    Elife  2020;9
  7. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
    Authors: Thomas C Et al.
    Cell  2019;179:498-513.e22
  8. Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants.
    Authors: Baj Et al.
    Neuropsychopharmacology  2012;37:1600
  9. NE causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+.
    Authors: Zemkova Et al.
    Endocrinology  2011;152:3842

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