Normal Goat IgG Control Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of Normal Goat IgG Control by Flow Cytometry SH-SY5Y human neuroblastoma cell line was stained with Goat Anti-Human/Mouse/Rat Ephrin-B2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF496, filled histogram) or Normal Goat IgG Isotype Control Antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107).
Detection of Mouse IgG by Immunocytochemistry/ Immunofluorescence Decreased macrophage recruitment correlates with decreased angiogenesis.A) Quantification of BrdU incorporation demonstrates that decreased macrophage infiltration does not significantly correlate with a change in epithelial cell proliferation (N.S. = not significant). B) Quantification of VWF staining reveals decreased blood vessels associated with epithelial structures in mammary glands from mice treated with B/B and anti-CX3CR1 blocking antibody compared with mice treated with B/B and IgG control antibody. *p<0.05. C, D) Representative images of VWF stained mammary glands from mice treated with B/B and either control IgG antibody (C) or anti-CX3CR1 (D). Green = VWF staining, blue = DAPI. Arrows indicate VWF-positive structures. Scale bars represent 50 µM. Results in each figure panel are representative of a minimum of three different mice for each treatment group and genotype. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.pone.0045877), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Mouse IgG by Immunocytochemistry/ Immunofluorescence iFGFR1 activation in vivo promotes recruitment of CX3CR1-positive macrophages.MMTV-iFGFR1 transgenic mice were treated with B/B in order to analyze the population of macrophages that are recruited to the mammary epithelium during early stages of iFGFR1-induced mammary tumorigenesis. A) MMTV-iFGFR1 mice treated with B/B demonstrated an increase in macrophage recruitment after 10 days as indicated by an increased in the number of F4/80 positive cells. MMTV-iFGFR1 mice treated with anti-CX3CR1 in conjunction with B/B demonstrated a reduction in macrophage recruitment at 10 days indicating that iFGFR1 activation is responsible for recruiting a subset of macrophages that express CX3CR1. ***p<0.0001. Error bars represent SEM. B) Representative image of macrophages associated with budding epithelial structures in mammary glands from mice treated with control IgG antibody. C) Representative image of macrophages associated with budding epithelial structures in mammary glands from mice treated with anti-CX3CR1. Red = F4/80 staining, blue = DAPI. Scale bars represent 50 µM. Results in each figure panel are representative of a minimum of three different mice for each treatment group and genotype. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.pone.0045877), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Normal Goat IgG Control by Immunocytochemistry/ Immunofluorescence iFGFR1 activation in vivo promotes recruitment of CX3CR1-positive macrophages.MMTV-iFGFR1 transgenic mice were treated with B/B in order to analyze the population of macrophages that are recruited to the mammary epithelium during early stages of iFGFR1-induced mammary tumorigenesis. A) MMTV-iFGFR1 mice treated with B/B demonstrated an increase in macrophage recruitment after 10 days as indicated by an increased in the number of F4/80 positive cells. MMTV-iFGFR1 mice treated with anti-CX3CR1 in conjunction with B/B demonstrated a reduction in macrophage recruitment at 10 days indicating that iFGFR1 activation is responsible for recruiting a subset of macrophages that express CX3CR1. ***p<0.0001. Error bars represent SEM. B) Representative image of macrophages associated with budding epithelial structures in mammary glands from mice treated with control IgG antibody. C) Representative image of macrophages associated with budding epithelial structures in mammary glands from mice treated with anti-CX3CR1. Red = F4/80 staining, blue = DAPI. Scale bars represent 50 µM. Results in each figure panel are representative of a minimum of three different mice for each treatment group and genotype. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.pone.0045877), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Rat Normal Goat IgG Control by Immunocytochemistry/ Immunofluorescence Blocking the tissue inhibitor of metalloproteinase type 1 (TIMP-1) in MSC-CM reduced its pro-oligodendroglial activity on cultured aNSCs. Representative immunocytochemical staining of 2′,3′-cyclic-nucleotide 3′-phosphodiesterase (CNPase)- (A) and GFAP-positive (B) cells treated either with control (no antibody), anti-TIMP-1, or immunoglobulin G (IgG) control pre-incubated with alpha -MEM or MSC-CM after 3 days in culture. (C) Quantification of CNPase- and GFAP-positive (D) cell numbers. Number of experiments n = 4. Statistical significance was calculated using a two-way ANOVA with Bonferroni posttest: * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32570968), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Western Blot Localisation of Sox17 staining in proliferative and secretory phase endometrial tissue and regulation by hormones. Within the proliferative (A) and secretory (B) endometrium, Sox17 localized to the glandular (open arrowheads) and luminal (closed arrowheads) epithelium, with staining appearing in an irregular, patchy, pattern. Smaller inset boxes show relevant IgG negative controls. Imaged at 20x magnification, scale bar = 50 μm. Treatment of endometrial luminal epithelial (ECC-1) cells with 10−8 M estrogen (estradiol)/10−7 M progesterone (medroxyprogesterone acetate) (, *p < 0.05) resulted in an upregulation of Sox17 protein, when compared to untreated, estradiol only (■, E) treatment groups. (C,D) Data presented as mean ± SEM, n = 5. Representative Western immunoblot shown. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31664088), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Western Blot Knockdown of SOX17 results in reduced expression in endometrial luminal epithelial cells. Transfection of ECC-1 cells with a CRISPR/Cas9 SOX17 knock down plasmid resulted in decreased SOX17 expression (KD1-5) when compared to untransfected control ECC-1 cells (ECC-1) and ECC-1 cells transfected with a control plasmid (CP). Analysed by Western immunoblot, representative blot shown. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31664088), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Osteoclast resorption of bony interspinous ligaments releases active TGF-beta to drive the progression of ossification in AS patients. e Immunostaining and f quantitative analysis of CD68-positive cells (brown) in the normal and HO-formed interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Progression of endochondral heterotopic ossification in AS patients. c Immunostaining and d quantitative analysis of collagen II-positive cells (brown) in the normal and chondrogenic interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Chondrocyte differentiation and cartilage formation in interspinous ligaments of AS patients before calcification. a Hematoxylin and eosin (H&E) staining and b Safranin O–Fast Green (SOFG) staining of normal and chondrogenic interspinous ligaments. In the AS group, the right panels show magnified views of the boxed area in the left panels. Scale bar: 100 μm (two panels on the right side); 25 μm (left panel). c Immunostaining and d quantitative analysis of collagen II-positive cells (brown) in the normal and chondrogenic interspinous ligaments (sagittal view). The bottom panels show a magnified view of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). e Immunostaining and f quantitative analysis of pSmad2/3-positive cells (brown) in the normal and chondrogenic interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). g Immunostaining and h quantitative analysis of pSmad1/5/8-positive cells (brown) in the normal and inflammatory interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). C, cartilage; L, ligament Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Progression of endochondral heterotopic ossification in AS patients. i Immunostaining and j quantitative analysis of pSmad2/3-positive cells (brown) in the normal ligaments and endochondral-ossified interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). k Immunostaining and l quantitative analysis of Osterix-positive cells (brown) in the normal and endochondral-ossified interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). m Immunostaining and n quantitative analysis of pSmad1/5/8-positive cells (brown) in the normal and inflammatory interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). B, bone; BM, bone marrow; C, cartilage Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Chondrocyte differentiation and cartilage formation in interspinous ligaments of AS patients before calcification. a Hematoxylin and eosin (H&E) staining and b Safranin O–Fast Green (SOFG) staining of normal and chondrogenic interspinous ligaments. In the AS group, the right panels show magnified views of the boxed area in the left panels. Scale bar: 100 μm (two panels on the right side); 25 μm (left panel). c Immunostaining and d quantitative analysis of collagen II-positive cells (brown) in the normal and chondrogenic interspinous ligaments (sagittal view). The bottom panels show a magnified view of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). e Immunostaining and f quantitative analysis of pSmad2/3-positive cells (brown) in the normal and chondrogenic interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). g Immunostaining and h quantitative analysis of pSmad1/5/8-positive cells (brown) in the normal and inflammatory interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). C, cartilage; L, ligament Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Elevated TGF-beta levels in the early inflammatory stage of AS. a Hematoxylin and eosin (H&E) staining and b Safranin O–Fast Green (SOFG) staining of normal and inflamed interspinous ligaments. In the AS group, the right panels show magnified views of the boxed area in the left panels. Scale bar: 100 μm (two panels on the right); 25 μm (left panel). c Immunostaining and d quantitative analysis of CD68-positive cells (brown) in the normal and inflamed interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). e Immunostaining and f quantitative analysis of pSmad2/3-positive cells (brown) in the normal and inflamed interspinous ligaments (sagittal view) in normal ligaments and inflammatory ligaments. The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). g Immunostaining and h quantitative analysis of pSmad1/5/8-positive cells (brown) in the normal and inflamed interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels) Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Osteoclast resorption of bony interspinous ligaments releases active TGF-beta to drive the progression of ossification in AS patients. g Immunostaining and h quantitative analysis of pSmad2/3-positive cells in the normal and HO-formed interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). i Immunostaining and j quantitative analysis of Osterix-positive cells (brown) in the normal and HO-formed interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel).Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Normal Goat IgG Control by Immunohistochemistry Progression of endochondral heterotopic ossification in AS patients.g Immunostaining and h quantitative analysis of the number of CD68-positive osteoclast (brown) surface (OCS) per bone surface (BS). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). i Immunostaining and j quantitative analysis of pSmad2/3-positive cells (brown) in the normal ligaments and endochondral-ossified interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). k Immunostaining and l quantitative analysis of Osterix-positive cells (brown) in the normal and endochondral-ossified interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panel); 25 μm (bottom panel). m Immunostaining and n quantitative analysis of pSmad1/5/8-positive cells (brown) in the normal and inflammatory interspinous ligaments (sagittal view). The bottom panels show magnified views of the boxed area in the top panels. Scale bar: 100 μm (top panels); 25 μm (bottom panels). B, bone; BM, bone marrow; C, cartilage Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33731675), licensed under a CC-BY license. Not internally tested by R&D Systems.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IgG
R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.
Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.
Product Datasheets
Citations for Normal Goat IgG Control
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner.
Authors: Reed, Johanna, Stone, Matthew, Beadnell, Thomas C, Ryu, Yungil, Griffin, Timothy, Schwertfeger, Kathryn
PLoS ONE, 2012-09-24;7(9):e45877.
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Targeting junctional adhesion molecule-C ameliorates sepsis-induced acute lung injury by decreasing CXCR4+ aged neutrophils
Authors: Y Hirano, Y Ode, M Ochani, P Wang, M Aziz
J. Leukoc. Biol., 2018-08-08;0(0):.
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TGF beta Impairs HNF1 alpha Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases.
Authors: Bisceglia F, Battistelli C, Noce V, et al.
Front Pharmacol
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IgG3 regulates tissue-like memory B cells in HIV-infected individuals
Authors: L Kardava, H Sohn, C Youn, JW Austin, W Wang, CM Buckner, JS Justement, VA Melson, GE Roth, MA Hand, KR Gittens, RW Kwan, MC Sneller, Y Li, TW Chun, PD Sun, SK Pierce, S Moir
Nat. Immunol., 2018-08-13;0(0):.
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Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis
Authors: Jeny F, Bernaudin JF, Valeyre D Et al.
Frontiers in immunology
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The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages
Authors: Y Manome, D Suzuki, A Mochizuki, E Saito, K Sasa, K Yoshimura, T Inoue, M Takami, K Inagaki, T Funatsu, R Kamijo
Oncotarget, 2018-07-06;9(52):29934-29943.
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Follistatin-like protein 1 increases transepithelial resistance in kidney epithelial cells through Akt signaling
Authors: F Chen, Q Hu, H Huang, B Chen, Y Xia, W Liu
Mol Med Rep, 2017-07-31;0(0):.
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Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8 Front.
Authors: Vazquez Rodriguez G, Abrahamsson A, Jensen LDE et al.
Immunol
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Stimulation of functional neuronal regeneration from M�ller glia in adult mice
Authors: NL Jorstad, MS Wilken, WN Grimes, SG Wohl, LS VandenBosc, T Yoshimatsu, RO Wong, F Rieke, TA Reh
Nature, 2017-07-26;548(7665):103-107.
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Human Papillomavirus Type 8 Interferes with a Novel C/EBPβ-Mediated Mechanism of Keratinocyte CCL20 Chemokine Expression and Langerhans Cell Migration.
Authors: Sperling T, Oldak M, Walch-Ruckheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S
PLoS Pathog., 2012-07-26;8(7):e1002833.
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Hypoxia inducible factor 1 alpha in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment
Authors: Qi D, Wei M, Jiao S et al.
Cell Death Dis
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Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling.
Authors: Valente AJ, Yoshida T, Clark RA et al.
Free Radic Biol Med.
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Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration
Authors: LK Thampy, KE Remy, AH Walton, Z Hong, K Liu, R Liu, V Yi, CD Burnham, RS Hotchkiss
PLoS ONE, 2018-06-26;13(6):e0199497.
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Nitration and glycation turn mature NGF into a toxic factor for motor neurons: a role for p75<sup>NTR</sup> and RAGE signaling in ALS
Authors: MJ Kim, MR Vargas, BA Harlan, KM Killoy, L Ball, S Comte-Walt, M Gooz, Y Yamamoto, JS Beckman, L Barbeito, M Pehar
Antioxid. Redox Signal., 2017-06-26;0(0):.
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GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function
Authors: Timper K, Del Rio-Martin A, Cremer AL et al.
Cell Metab.
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Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
J Neuroinflammation, 2015-06-16;12(0):119.
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Kruppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome
Authors: Yang M, Guo Q, Peng H et al.
J. Exp. Med.
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Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.
Authors: Valente AJ, Yoshida T, Izadpanah R et al.
Cell Signal.
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Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms.
Authors: Xu, C, Wang, L Et al.
J Am Soc Nephrol
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Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function
Authors: A Guimarães-, T Neff, AJ Dupuy, MJ Goodheart
Dev Biol, 2016-04-19;0(0):.
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TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF
Authors: HE Seberg, E Van Otterl, SK Loftus, H Liu, G Bonde, R Sompallae, DE Gildea, JF Santana, JR Manak, WJ Pavan, T Williams, RA Cornell
PLoS Genet, 2017-03-01;13(3):e1006636.
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Granulocyte colony-stimulating factor mediates bone loss via the activation of IL-1?/JNK signaling pathway in murine Staphylococcus aureus-induced osteomyelitis
Authors: Song, M;Deng, M;Peng, Z;Dai, F;Wang, Y;Shu, W;Zhou, X;Zhang, J;Hou, Y;Yu, B;
International immunopharmacology
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay -
An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial-Mesenchymal Transition and Migration of Prostate Cancer Cell Lines
Authors: Jotatsu, Y;Sung, SY;Wu, MH;Takeda, S;Hirata, Y;Maeda, K;Fang, SB;Chen, KC;Shigemura, K;
International journal of molecular sciences
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Airway epithelial CD47 plays a critical role in inducing influenza virus-mediated bacterial super-infection
Authors: Moon, S;Han, S;Jang, IH;Ryu, J;Rha, MS;Cho, HJ;Yoon, SS;Nam, KT;Kim, CH;Park, MS;Seong, JK;Lee, WJ;Yoon, JH;Chung, YW;Ryu, JH;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Endothelial HIF?-PDGF-B to smooth muscle Beclin1 signaling sustains pathological muscularization in pulmonary hypertension
Authors: Saddouk, FZ;Kuzemczak, AP;Saito, J;Greif, DM;
JCI insight
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures
Authors: Harary Søndergaard, R;Drozd Højgaard, L;Haack-Sørensen, M;Hoeeg, C;Mønsted Johansen, E;Follin, B;Kastrup, J;Ekblond, A;Juhl, M;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Podocalyxin promotes the formation of compact and chemoresistant cancer spheroids in high grade serous carcinoma
Authors: Le Tran, N;Wang, Y;Bilandzic, M;Stephens, A;Nie, G;
Scientific reports
Species: Human
Sample Types: Spheroid
Applications: Immunohistochemistry -
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release
Authors: Tufan, T;Comertpay, G;Villani, A;Nelson, GM;Terekhova, M;Kelley, S;Zakharov, P;Ellison, RM;Shpynov, O;Raymond, M;Sun, J;Chen, Y;Bockelmann, E;Stremska, M;Peterson, LW;Boeckaerts, L;Goldman, SR;Etchegaray, JI;Artyomov, MN;Peri, F;Ravichandran, KS;
Nature
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity
Authors: Dos Santos, JC;Moreno, M;Teufel, LU;Chilibroste, S;Keating, ST;Groh, L;Domínguez-Andrés, J;Williams, DL;Ma, Z;Lowman, DW;Ensley, HE;Novakovic, B;Ribeiro-Dias, F;Netea, MG;Chabalgoity, JA;Joosten, LAB;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female mice
Authors: Silveira Prudente, A;Hoon Lee, S;Roh, J;Luckemeyer, DD;Cohen, CF;Pertin, M;Park, CK;Suter, MR;Decosterd, I;Zhang, JM;Ji, RR;Berta, T;
Brain, behavior, and immunity
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay -
Apoptosis recognition receptors regulate skin tissue repair in mice
Authors: Justynski, O;Bridges, K;Krause, W;Forni, MF;Phan, QM;Sandoval-Schaefer, T;Carter, K;King, DE;Hsia, HC;Gazes, MI;Vyce, SD;Driskell, RR;Miller-Jensen, K;Horsley, V;
eLife
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1?
Authors: Azumi, Y;Koma, YI;Tsukamoto, S;Kitamura, Y;Ishihara, N;Yamanaka, K;Nakanishi, T;Miyako, S;Urakami, S;Tanigawa, K;Kodama, T;Nishio, M;Shigeoka, M;Kakeji, Y;Yokozaki, H;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury in murine males
Authors: Rogala, S;Ali, T;Melissari, MT;Währisch, S;Schuster, P;Sarre, A;Emídio, RC;Boettger, T;Rogg, EM;Kaur, J;Krishnan, J;Dumbovi?, G;Dimmeler, S;Ounzain, S;Pedrazzini, T;Herrmann, BG;Grote, P;
Nature communications
Species: Mouse
Sample Types: Cell Lysates
Applications: RNA Immunoprecipitation Contro -
Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmpgt/gt mouse model of slowly progressing liver fibrosis
Authors: Antwi, MB;Dumitriu, G;Simón-Santamaria, J;Romano, JS;Li, R;Smedsrød, B;Vik, A;Eskild, W;Sørensen, KK;
PloS one
Species: Mouse, Transgenic Mouse
Sample Types: Whole Tissue
Applications: IHC -
Depletion of slow-cycling PDGFR?+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis
Authors: Di Carlo, SE;Raffenne, J;Varet, H;Ode, A;Granados, DC;Stein, M;Legendre, R;Tuckermann, J;Bousquet, C;Peduto, L;
Nature immunology
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control -
Empagliflozin Reverses Oxidized LDL-Induced RECK Suppression, Cardiotrophin-1 Expression, MMP Activation, and Human Aortic Smooth Muscle Cell Proliferation and Migration
Authors: Chandrasekar, B;Mummidi, S;DeMarco, VG;Higashi, Y;
Mediators of inflammation
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot Control -
Pro-tumor Tfh2 cells induce detrimental IgG4 production and PGE2-dependent IgE inhibition in pancreatic cancer
Authors: De Monte, L;Clemente, F;Ruggiero, E;Pini, R;Ceraolo, MG;Schiavo Lena, M;Balestrieri, C;Lazarevic, D;Belfiori, G;Crippa, S;Balzano, G;Falconi, M;Doglioni, C;Bonini, C;Reni, M;Protti, MP;
EBioMedicine
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2
Authors: Rogers, S;Zhang, C;Anagnostidis, V;Liddle, C;Fishel, ML;Gielen, F;Scholpp, S;
Proceedings of the National Academy of Sciences of the United States of America
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
Authors: Molfetta, R;Lecce, M;Milito, ND;Putro, E;Pietropaolo, G;Marangio, C;Scarno, G;Moretti, M;De Smaele, E;Santini, T;Bernardini, G;Sciumè, G;Santoni, A;Paolini, R;
Cell death & disease
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling
Authors: Militi, S;Nibhani, R;Jalali, M;Pauklin, S;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: ICC Control -
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics
Authors: Mouti MA, Deng S, Pook M et al.
Nature communications
-
CD105 expression in cancer-associated fibroblasts: a biomarker for bone metastasis in early invasive ductal breast cancer patients
Authors: María Belén Giorello, Leandro Marcelo Martinez, Francisco Raúl Borzone, María Del Rosario Padin, María Florencia Mora, Ina Sevic et al.
Front Cell Dev Biol
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Inhibitory Effects of Simvastatin on IL-33-Induced MCP-1 via the Suppression of the JNK Pathway in Human Vascular Endothelial Cells
Authors: Umebashi, K;Yamamoto, M;Tokito, A;Sudou, K;Takenoshita, Y;Jougasaki, M;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cell
Applications: Functional Assay - Control -
Impaired regulatory function of granzyme B-producing B cells against T cell inflammatory responses in lupus mice
Authors: Jimeng Xue, Liling Xu, Hua Zhong, Mingxin Bai, Xin Li, Ranran Yao et al.
Lupus Science & Medicine
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The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production
Authors: Kakae, M;Nakajima, H;Tobori, S;Kawashita, A;Miyanohara, J;Morishima, M;Nagayasu, K;Nakagawa, T;Shigetomi, E;Koizumi, S;Mori, Y;Kaneko, S;Shirakawa, H;
Science advances
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells, In Vivo
Applications: Neutralization Control, In vivo assay -
Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function
Authors: De Gasperi, R;Csernoch, L;Dienes, B;Gonczi, M;Chakrabarty, JK;Goeta, S;Aslan, A;Toro, CA;Karasik, D;Brown, LM;Brotto, M;Cardozo, CP;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Lysates
Applications: Immunoprecipitation Control -
Phosphorylation of alpha B-Crystallin Involves Interleukin-1 beta -Mediated Intracellular Retention in Retinal Müller Cells: A New Mechanism Underlying Fibrovascular Membrane Formation
Authors: Yamamoto, T;Kase, S;Shinkai, A;Murata, M;Kikuchi, K;Wu, D;Kageyama, Y;Shinohara, M;Sasase, T;Ishida, S;
Investigative ophthalmology & visual science
Species: Rat
Sample Types: Whole Cells
Applications: Neutralization Control -
CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling
Authors: Serwe, G;Kachaner, D;Gagnon, J;Plutoni, C;Lajoie, D;Duramé, E;Sahmi, M;Garrido, D;Lefrançois, M;Arseneault, G;Saba-El-Leil, MK;Meloche, S;Emery, G;Therrien, M;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Calcineurin regulates aldosterone production via dephosphorylation of NFATc4
Authors: Berber, M;Leng, S;Wengi, A;Winter, DV;Odermatt, A;Beuschlein, F;Loffing, J;Breault, DT;Penton, D;
JCI insight
Species: Human
Sample Types: Cell Culture Supernates
Applications: ChIP -
IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils
Authors: Bénard, A;Mittelstädt, A;Klösch, B;Glanz, K;Müller, J;Schoen, J;Nüse, B;Brunner, M;Naschberger, E;Stürzl, M;Mattner, J;Muñoz, LE;Sohn, K;Grützmann, R;Weber, GF;
Cell reports
Species: Mouse
Sample Types:
Applications: In Vivo -
BCA101 is a Tumor-Targeted Bifunctional Fusion Antibody that Simultaneously Inhibits EGFR and TGF-beta Signalling to Durably Suppress Tumor Growth
Authors: SR Boreddy, R Nair, PK Pandey, A Kuriakose, SB Marigowda, C Dey, A Banerjee, H Kulkarni, M Sagar, SR Krishn, S Rao, M A R, V Tiwari, B Alke, PK Mv, M Shri, C Dhamne, S Patel, P Sharma, S Periyasamy, J Bhatnagar, MA Kuriakose, RB Reddy, A Suresh, S Sreenivas, N Govindappa, PR Moole, U Bughani, SL Tan, P Nair
Cancer Research, 2023-06-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance
Authors: Yu Li, Pablo Guaman Tipan, Hilary J Selden, Jayashree Srinivasan, Laura P Hale, Lauren I R Ehrlich
eLife
-
Extracellular CIRP Induces Calpain Activation in Neurons via PLC-IP3-Dependent Calcium Pathway
Authors: Archna Sharma, Ezgi Sari, Yongchan Lee, Shivani Patel, Max Brenner, Philippe Marambaud et al.
Molecular Neurobiology
-
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice
Authors: Kessel, JC;Weiskirchen, R;Schröder, SK;
International journal of molecular sciences
Species: Transgenic Mouse
Sample Types: Whole Tissue
Applications: IHC -
Neutralization of excessive levels of active TGF-beta 1 reduces MSC recruitment and differentiation to mitigate peritendinous adhesion
Authors: YuSheng Li, Xiao Wang, Bo Hu, Qi Sun, Mei Wan, Andrew Carr et al.
Bone Research
-
Netrin-1 promotes the immunosuppressive activity of MDSCs in colorectal cancer
Authors: X Xia, Z Mao, W Wang, J Ma, J Tian, S Wang, K Yin
Cancer Immunology Research, 2023-05-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Intestinal cell type-specific communication networks underlie homeostasis and response to Western diet
Authors: Yu-Chen Wang, Yang Cao, Calvin Pan, Zhiqiang Zhou, Lili Yang, Aldons J. Lusis
Journal of Experimental Medicine
-
Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease
Authors: YC Hsu, CC Chang, CC Hsieh, YT Huang, YH Shih, HC Chang, PJ Chang, CL Lin
International Journal of Molecular Sciences, 2023-04-21;24(8):.
Species: Mouse
Sample Types: Whole Cell
Applications: Bioassay -
Interleukin-15 deficient rats have reduced osteopontin at the maternal-fetal interface
Authors: Kelly J. Baines, Michelle S. Klausner, Violet S. Patterson, Stephen J. Renaud
Frontiers in Cell and Developmental Biology
-
Expansion of circulating stem-like CD8+ T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice
Authors: K Onyshchenk, R Luo, E Guffart, S Gaedicke, AL Grosu, E Firat, G Niedermann
Nature Communications, 2023-04-12;14(1):2087.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
CD34+ cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis
Authors: Y Song, J Yang, T Li, X Sun, R Lin, Y He, K Sun, J Han, G Yang, X Li, B Liu, D Yang, G Dang, X Ma, X Du, B Zhang, Y Hu, W Kong, X Wang, H Zhang, Q Xu, J Feng
Science Advances, 2023-04-12;9(15):eadd2632.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves
Authors: I Spera, N Cousin, M Ries, A Kedracka, A Castillo, S Aleandri, M Vladymyrov, JA Mapunda, B Engelhardt, P Luciani, M Detmar, ST Proulx
EBioMedicine, 2023-04-10;91(0):104558.
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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway
Authors: Q Ye, J Jo, CY Wang, H Oh, TJ Choy, K Kim, A Dâ Alessan, YK Reshetnyak, SY Jung, Z Chen, SP Marrelli, HK Lee
bioRxiv : the preprint server for biology, 2023-04-03;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Glioblastoma induces the recruitment and differentiation of hybrid neutrophils from skull bone marrow
Authors: BM Lad, AS Beniwal, S Jain, P Shukla, J Jung, SS Shah, G Yagnik, H Babikir, AT Nguyen, S Gill, JS Young, A Lui, D Salha, A Diaz, MK Aghi
bioRxiv : the preprint server for biology, 2023-03-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
Authors: Y Itoh, V Sahni, SJ Shnider, H McKee, JD Macklis
Cell Reports, 2023-03-17;42(3):112182.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Isotype Control -
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
Authors: Luan D, Dadpey B, Zaid J et al.
Diabetes
-
Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients
Authors: Valeria Fernández Vallone, Francisco Raúl Borzone, Leandro Marcelo Martinez, María Belén Giorello, Hosoon Choi, Federico Dimase et al.
Frontiers in Oncology
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Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
Authors: Julia Elrod, Moritz Lenz, Antonia Kiwit, Lina Armbrust, Lavinia Schönfeld, Konrad Reinshagen et al.
Frontiers in Immunology
-
Targeting UGCG overcomes resistance to lysosomal autophagy inhibition
Authors: V Jain, SL Harper, AM Versace, D Fingerman, GS Brown, M Bhardwaj, MAS Crissey, AR Goldman, G Ruthel, Q Liu, A Zivkovic, H Stark, M Herlyn, PA Gimotty, DW Speicher, RK Amaravadi
Cancer Discovery, 2023-02-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
MANF regulates neuronal survival and UPR through its ER-located receptor IRE1alpha
Authors: V Kovaleva, LY Yu, L Ivanova, O Shpironok, J Nam, A Eesmaa, EP Kumpula, S Sakson, U Toots, M Ustav, JT Huiskonen, MH Voutilaine, P Lindholm, M Karelson, M Saarma
Cell Reports, 2023-02-03;42(2):112066.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation Control -
Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease
Authors: Y Qiu, X Shen, O Ravid, D Atrakchi, D Rand, AE Wight, HJ Kim, S Liraz-Zalt, I Cooper, M Schnaider, H Cantor
Proceedings of the National Academy of Sciences of the United States of America, 2023-02-02;120(6):e2218915120.
Species: Mouse
Sample Types: Recombinant Protein
Applications: ELISA Control -
IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines
Authors: Van Anh Do-Thi, Sang Min Park, Song Mi Park, Hye Jin Jeong, Geunyoung Cho, Hyun-Jung An et al.
Cancer Research Communications
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A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models
Authors: B van Lenger, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, M Calvert, S Hummel, S Lianoglou, ME Pizzo, R Prorok, E Thomsen, LM Bartos, P Beumers, A Capell, SS Davis, L de Weerd, JC Dugas, J Duque, T Earr, K Gadkar, T Giese, A Gill, J Gnörich, C Ha, M Kannuswamy, DJ Kim, ST Kunte, LH Kunze, D Lac, K Lechtenber, AW Leung, CC Liang, I Lopez, P McQuade, A Modi, VO Torres, HN Nguyen, I Pesämaa, N Propson, M Reich, Y Robles-Col, K Schlepckow, L Slemann, H Solanoy, JH Suh, RG Thorne, C Vieira, K Wind-Mark, K Xiong, YJY Zuchero, D Diaz, MS Dennis, F Huang, K Scearce-Le, RJ Watts, C Haass, JW Lewcock, G Di Paolo, M Brendel, PE Sanchez, KM Monroe
Nature Neuroscience, 2023-01-12;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors
Authors: K Ning, W Zou, P Xu, F Cheng, EY Zhang, A Zhang-Chen, S Kleiboeker, J Qiu
Science Advances, 2023-01-11;9(2):eade0869.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing
Authors: Y Zheng, X Dong, S Chen, Y He, J An, M Liu, L He, Y Zhang
BMC Oral Health, 2023-01-10;23(1):14.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner
Authors: Gregory P. Takacs, Christian J. Kreiger, Defang Luo, Guimei Tian, Julia S. Garcia, Loic P. Deleyrolle et al.
Frontiers in Immunology
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Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation
Authors: I Petit, A Levy, S Estrach, CC Féral, AG Trentin, F Dingli, D Loew, J Qu, H Zhou, C Théry, C Prunier, D Aberdam, O Ferrigno
Scientific Reports, 2022-12-22;12(1):22131.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Endogenous secretory leukocyte protease inhibitor (SLPI) inhibits microbial-induced monocyte activation
Authors: S Nugteren, Y Simons-Oos, CL Menckeberg, DH Hulleman-v, DJ Lindenberg, JN Samsom
European Journal of Immunology, 2022-12-22;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice
Authors: Y Wang, S Zhang, Z Lan, V Doan, B Kim, S Liu, M Zhu, VL Hull, S Rihani, CL Zhang, JA Gray, F Guo
Cell Reports, 2022-12-20;41(12):111842.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury
Authors: G Xiao, R Kumar, Y Komuro, J Burguet, V Kakarla, I Azizkhania, SA Sheth, CK Williams, XR Zhang, M Macknicki, A Brumm, R Kawaguchi, P Mai, N Kaneko, HV Vinters, ST Carmichael, LA Havton, C DeCarli, JD Hinman
Cell Reports, 2022-12-20;41(12):111848.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees
Authors: J Van Coilli, T Pongracz, J Rahmöller, HJ Chen, CE Geyer, LA van Vught, JS Buhre, T Šušti?, TLJ van Osch, M Steenhuis, W Hoepel, W Wang, AS Lixenfeld, J Nouta, S Keijzer, F Linty, R Visser, MD Larsen, EL Martin, I Künsting, S Lehrian, V von Kopylo, C Kern, HB Lunding, M de Winther, N van Mourik, T Rispens, T Graf, MA Slim, RP Minnaar, MK Bomers, JJ Sikkens, APJ Vlaar, CE van der Sc, J den Dunnen, M Wuhrer, M Ehlers, G Vidarsson, Fatebenefr, UMC COVID-
EBioMedicine, 2022-12-16;87(0):104408.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection
Authors: WJ Brewer, AM Xet-Mull, A Yu, MI Sweeney, EM Walton, DM Tobin
Cell Reports, 2022-12-13;41(11):111817.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke
Authors: D Spitzer, T Puetz, M Armbrust, M Dunst, J Macas, F Croll, KH Plate, Y Reiss, S Liebner, PN Harter, S Guérit, K Devraj
Scientific Reports, 2022-12-03;12(1):20925.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Cell Culture, In Vivo -
The envelope protein of Zika virus interacts with apolipoprotein E early in the infectious cycle and this interaction is conserved on the secreted viral particles
Authors: Yannick Tréguier, Jade Cochard, Julien Burlaud-Gaillard, Roxane Lemoine, Philippe Chouteau, Philippe Roingeard et al.
Virology Journal
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Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells
Authors: Christophe Boudesco, Annelies Nonneman, Alessandro Cinti, Paola Picardi, Loredana Redaelli, Sofie Swijsen et al.
Glia
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Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs
Authors: SI Gringhuis, TM Kaptein, EBM Remmerswaa, A Drewniak, BA Wevers, B Theelen, GRAM D'Haens, T Boekhout, TBH Geijtenbee
Nature Immunology, 2022-12-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Efficient antigen delivery by dendritic cell-targeting peptide via nucleolin confers superior vaccine effects in mice
Authors: Teppei Matsuda, Kazuki Misato, Shigeyuki Tamiya, Yasuhiro Akeda, Ikuhiko Nakase, Etsushi Kuroda et al.
iScience
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The E3 ligase subunit FBXO45 binds the interferon-lambda receptor and promotes its degradation during influenza virus infection
Authors: M Tsai, W Osman, J Adair, R ElMergawy, L Chafin, F Johns, D Farkas, A Elhance, J Londino, RK Mallampall
The Journal of Biological Chemistry, 2022-11-13;0(0):102698.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Data supporting the roles of BAP1, STING, and IFN-beta in ISGF3 activation in ccRCC
Authors: LE Langbein, E Sementino, Z Zhong, W Jiang, L Li, JR Testa, H Yang
Data in Brief, 2022-11-11;45(0):108743.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Immunological and Pathological Peculiarity of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant
Authors: Sunhee Lee, Gun Young Yoon, Su Jin Lee, Young-Chan Kwon, Hyun Woo Moon, Yu-Jin Kim et al.
Microbiology Spectrum
-
Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair
Authors: EC Jeffery, TLA Mann, JA Pool, Z Zhao, SJ Morrison
Cell Stem Cell, 2022-10-21;29(11):1547-1561.e6.
Species: Mouse
Sample Types: Whole Cells
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Anti-Allergic Activity of Fucoidan Can Be Enhanced by Coexistence with Quercetin
Authors: M Mizuno, A Fujioka, S Bitani, KI Minato, H Sakakibara
International Journal of Molecular Sciences, 2022-10-12;23(20):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control -
Lacticaseibacillus rhamnosus R0011 secretome attenuates Salmonella enterica serovar Typhimurium secretome-induced intestinal epithelial cell monolayer damage and pro-inflammatory mediator production in intestinal epithelial cell and antigen-presenting cell co-cultures
Authors: Michael P. Jeffrey, Chad W. MacPherson, Thomas A. Tompkins, Julia M. Green-Johnson
Frontiers in Microbiology
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Effects of Oral Glutamine Supplementation, Birthweight and Age on Colonic Morphology and Microbiome Development in Male Suckling Piglets
Authors: J Schulze Ho, J Schregel, QL Sciascia, Z Li, A Tuchschere, W Vahjen, CC Metges, J Zentek
Microorganisms, 2022-09-25;10(10):.
Species: Porcine
Sample Types: Whole Tissue
Applications: IHC -
Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells
Authors: GL Lehmann, M Ginsberg, DJ Nolan, C Rodríguez, J Martínez-G, S Zeng, AP Voigt, RF Mullins, S Rafii, E Rodriguez-, I Benedicto
Cells, 2022-09-24;11(19):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
Authors: AM Mello, T Ngodup, Y Lee, KL Donahue, J Li, A Rao, ES Carpenter, HC Crawford, M Pasca di M, KE Lee
Oncogenesis, 2022-09-15;11(1):56.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Targeting hepatic oxidative stress rescues bone loss in liver fibrosis
Authors: S Sonoda, S Murata, H Yamaza, R Yuniartha, J Fujiyoshi, K Yoshimaru, T Matsuura, Y Oda, S Ohga, T Tajiri, T Taguchi, T Yamaza
Molecular Metabolism, 2022-09-13;66(0):101599.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Integrin beta1, PDGFRbeta, and type II collagen are essential for meniscus regeneration by synovial mesenchymal stem cells in rats
Authors: T Kitahashi, R Kogawa, K Nakamura, I Sekiya
Scientific Reports, 2022-08-19;12(1):14148.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
Stress Granules Determine the Development of Obesity-Associated Pancreatic Cancer
Authors: Guillaume Fonteneau, Alexandra Redding, Hannah Hoag-Lee, Edward S. Sim, Stefan Heinrich, Matthias M. Gaida et al.
Cancer Discovery
-
IL-24 intrinsically regulates Th17 cell pathogenicity in mice
Authors: Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl et al.
Journal of Experimental Medicine
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Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood–brain barrier in acute ischemic stroke
Authors: Daniel Spitzer, Sylvaine Guérit, Tim Puetz, Maryam I. Khel, Moritz Armbrust, Maika Dunst et al.
Acta Neuropathologica
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Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells
Authors: Y Xu, M Twarog, N Li, A Banks, J Schustak, Y Bao, Q Huang, QG Medley
PLoS ONE, 2022-07-28;17(7):e0271656.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Kallistatin prevents ovarian hyperstimulation syndrome by regulating vascular leakage
Authors: J Huang, Y Mao, Q Li, H Hong, N Tang, X Kang, Y Huang, J Liu, Q Gong, Y Yao, L Li
Journal of Cellular and Molecular Medicine, 2022-07-21;26(16):4613-4623.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death
Authors: Andy Shao, Antonio Jacobo Lopez, JiaJia Chen, Addy Tham, Seanne Javier, Alejandra Quiroz et al.
Disease Models & Mechanisms
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Sulfavant A as the first synthetic TREM2 ligand discloses a homeostatic response of dendritic cells after receptor engagement
Authors: Carmela Gallo, Emiliano Manzo, Giusi Barra, Laura Fioretto, Marcello Ziaco, Genoveffa Nuzzo et al.
Cellular and Molecular Life Sciences
-
Neuroinflammation in the anterior cingulate cortex: the potential supraspinal mechanism underlying the mirror-image pain following motor fiber injury
Authors: QY Li, SX Chen, JY Liu, PW Yao, YW Duan, YY Li, Y Zang
Journal of Neuroinflammation, 2022-06-20;19(1):162.
Species: Rat
Sample Types: In Vivo
Applications: Isotype Control -
Metabolic Syndrome in Psoriasis Is Associated With Upregulation of CXCL16 on Monocytes and a Dysbalance in Innate Lymphoid Cells
Authors: Lisa Schielke, Nick Zimmermann, Sarah Hobelsberger, Julian Steininger, Anne Strunk, Kristin Blau et al.
Frontiers in Immunology
-
CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues
Authors: Micha L. Davila, Ming Xu, Chengyu Huang, Erin R. Gaddes, Levi Winter, Margherita T. Cantorna et al.
iScience
-
PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
Authors: D Thumkeo, S Punyawatth, S Prasongtan, R Matsuura, K Arima, H Nie, R Yamamoto, N Aoyama, H Hamaguchi, S Sugahara, S Takeda, V Charoensaw, A Tanaka, S Sakaguchi, S Narumiya
Cell Reports, 2022-06-07;39(10):110914.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control -
Podocalyxin Expressed in Antigen Presenting Cells Promotes Interaction With T Cells and Alters Centrosome Translocation to the Contact Site
Authors: Laura Amo, Javier Díez-García, Estíbaliz Tamayo-Orbegozo, Natalia Maruri, Susana Larrucea
Frontiers in Immunology
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Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis
Authors: Rajia Bahri, Orsolya Kiss, Ian Prise, Karen M. Garcia-Rodriguez, Haris Atmoko, Julia M. Martínez-Gómez et al.
Frontiers in Immunology
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Insulin-like growth factor 5 associates with human A� plaques and promotes cognitive impairment
Authors: S Rauskolb, T Andreska, S Fries, CR von Collen, R Blum, CM Monoranu, C Villmann, M Sendtner
Acta neuropathologica communications, 2022-05-05;10(1):68.
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: IHC Control -
Insect cell expression and purification of recombinant SARS‐COV‐2 spike proteins that demonstrate ACE2 binding
Authors: Lucas R. Struble, Audrey L. Smith, William E. Lutz, Gabrielle Grubbs, Satish Sagar, Kenneth W. Bayles et al.
Protein Science
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Effects of oral glutamine supplementation on jejunal morphology, development, and amino acid profiles in male low birth weight suckling piglets
Authors: J Schregel, J Schulze Ho, QL Sciascia, Z Li, S Görs, A Eggert, A Tuchschere, J Zentek, CC Metges
PLoS ONE, 2022-04-27;17(4):e0267357.
Species: Porcine
Sample Types: Whole Tissue
Applications: IHC -
FcgammaR-mediated SARS-CoV-2 infection of monocytes activates inflammation
Authors: C Junqueira, Â Crespo, S Ranjbar, LB de Lacerda, M Lewandrows, J Ingber, B Parry, S Ravid, S Clark, MR Schrimpf, F Ho, C Beakes, J Margolin, N Russell, K Kays, J Boucau, U Das Adhika, SM Vora, V Leger, L Gehrke, L Henderson, E Janssen, D Kwon, C Sander, J Abraham, MB Goldberg, H Wu, G Mehta, S Bell, AE Goldfeld, MR Filbin, J Lieberman
Nature, 2022-04-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Neutralization Control -
Inhibition of Integrin alpha v beta 6 Activation of TGF‐ beta Attenuates Tendinopathy
Authors: Xiao Wang, Shen Liu, Tao Yu, Senbo An, Ruoxian Deng, Xiaohua Tan et al.
Advanced Science
-
Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling
Authors: A Skopál, T Kéki, PÁ Tóth, B Csóka, B Koscsó, ZH Német, L Antonioli, A Ivessa, F Ciruela, L Virág, G Haskó, E Kókai
The Journal of Biological Chemistry, 2022-03-31;0(0):101888.
Species: Mouse
Sample Types: Cell Lysates
Applications: Immunoprecipitation Control -
Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
Authors: Ying Yu, Yingjie Shen, Siyi Zhang, Nan Wang, Lan Luo, Xinyi Zhu et al.
International Journal of Molecular Sciences
-
SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids
Authors: Y Menuchin-L, A Schreiber, A Lecanda, A Mecate-Zam, L Brunotte, OE Psathaki, S Ludwig, T Rauen, HR Schöler
Stem Cell Reports, 2022-03-24;0(0):.
Species: Human
Sample Types: Organoid
Applications: Neutralization -
Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury
Authors: K Molnár, B Nógrádi, R Kristóf, Á Mészáros, K Pajer, L Siklós, A Nógrádi, I Wilhelm, IA Krizbai
Journal of Neuroinflammation, 2022-03-19;19(1):68.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot -
Functional in vivo assessment of stem cell-secreted pro-oligodendroglial factors
Authors: Patrick Schira-Heinen, Iria Samper Schira-Heinen, IriaSamper Estrada, Veronica Estrada
Neural Regeneration Research
-
CD8+ T cell-derived IL-13 increases macrophage IL-10 to resolve neuropathic pain
Authors: SK Singh, K Krukowski, GO Laumet, D Weis, JF Alexander, CJ Heijnen, A Kavelaars
JCI Insight, 2022-03-08;7(5):.
Species: Mouse
Sample Types: Whole Cell
Applications: Functional Assay, In Vivo -
Limited extent and consequences of pancreatic SARS-CoV-2 infection
Authors: Verena van der Heide, Sonia Jangra, Phillip Cohen, Raveen Rathnasinghe, Sadaf Aslam, Teresa Aydillo et al.
Cell Reports
-
Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche
Authors: K Kos, MA Aslam, R van de Ven, MD Wellenstei, W Pieters, A van Weverw, DEM Duits, K van Pul, CS Hau, K Vrijland, D Kaldenbach, EAM Raeven, SA Quezada, R Beyaert, H Jacobs, TD de Gruijl, KE de Visser
Cell Reports, 2022-03-01;38(9):110447.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NF kappa B activation
Authors: Hyun-Jung Kim, Woo-Jin Kim, Hye-Rim Shin, Hee-In Yoon, Jae-I Moon, Eunji Lee et al.
Cellular and Molecular Life Sciences
-
Nucleotide Excision Repair Pathway Activity Is Inhibited by Airborne Particulate Matter (PM10) through XPA Deregulation in Lung Epithelial Cells
Authors: EM Quezada-Ma, YI Chirino, ME Gonsebatt, R Morales-Bá, Y Sánchez-Pé, CM García-Cue
International Journal of Molecular Sciences, 2022-02-17;23(4):.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection
Authors: X Liu, W Chen, G Zhu, H Yang, W Li, M Luo, C Shu, Z Zhou
Cell Discovery, 2022-02-08;8(1):11.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC Control -
Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry
Authors: Mathieu Claireaux, Rémy Robinot, Jérôme Kervevan, Mandar Patgaonkar, Isabelle Staropoli, Anne Brelot et al.
Nature Communications
-
Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency
Authors: Evgeniia Borisova, Ken Nishimura, Yuri An, Miho Takami, Jingyue Li, Dan Song et al.
iScience
-
Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain
Authors: LJ Fan, HM Kan, XT Chen, YY Sun, LP Chen, W Shen
Molecular pain, 2022-01-01;18(0):1744806922107.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo Control -
B7-H3 Suppresses Antitumor Immunity via the CCL2–CCR2–M2 Macrophage Axis and Contributes to Ovarian Cancer Progression
Authors: Taito Miyamoto, Ryusuke Murakami, Junzo Hamanishi, Kenji Tanigaki, Yuko Hosoe, Nathan Mise et al.
Cancer Immunology Research
-
Establishment of large canine hepatocyte spheroids by mixing vascular endothelial cells and canine adipose-derived mesenchymal stem cells
Authors: A Ichikawa, S Neo, R Nukui, Y Yamada, S Nitta, H Iwaki, Y Yanagi, K Nakayama, S Sato, S Tateishi, M Hisasue
Regenerative Therapy, 2021-12-29;19(0):1-8.
Species: Canine
Sample Types: Spheroids
Applications: IHC Control -
Neutrophil-Mediated Lung Injury Both via TLR2-Dependent Production of IL-1 alpha and IL-12 p40, and TLR2-Independent CARDS Toxin after Mycoplasma pneumoniae Infection in Mice
Authors: Shigeyuki Tamiya, Eisuke Yoshikawa, Monami Ogura, Etsushi Kuroda, Koichiro Suzuki, Yasuo Yoshioka
Microbiology Spectrum
-
Pro-Resolving Factors Released by Macrophages After Efferocytosis Promote Mucosal Wound Healing in Inflammatory Bowel Disease
Authors: Omayra Martin-Rodriguez, Thierry Gauthier, Francis Bonnefoy, Mélanie Couturier, Anna Daoui, Cécile Chagué et al.
Frontiers in Immunology
-
TGF-beta 1 potentiates V gamma 9Vδ2 T cell adoptive immunotherapy of cancer
Authors: Richard E. Beatson, Ana C. Parente-Pereira, Leena Halim, Domenico Cozzetto, Caroline Hull, Lynsey M. Whilding et al.
Cell Reports Medicine
-
Absence of COVID-19-associated changes in plasma coagulation proteins and pulmonary thrombosis in the ferret model
Authors: IC Kreft, RRA Winiarczyk, FJ Tanis, C van der Zw, KS Schmitz, AJ Hoogendijk, RL de Swart, A Moscona, M Porotto, DCF Salvatori, RD de Vries, MPM de Maat, M van den Bi, BJM van Vlijme, Dutch Covi
Thrombosis Research, 2021-12-21;210(0):6-11.
Species: Ferret
Sample Types: Whole Tissue
Applications: IHC Control -
Intestinal ischemia‑reperfusion induces the release of IL‑17A to regulate cell inflammation, apoptosis and barrier damage
Authors: Li Xiao, Wan-Hua Zhang, Yin Huang, Peng Huang
Experimental and Therapeutic Medicine
-
AXL receptor is required for Zika virus strain MR-766 infection in human glioblastoma cell lines
Authors: Samuel D. Zwernik, Beau H. Adams, Daniel A. Raymond, Catherine M. Warner, Amin B. Kassam, Richard A. Rovin et al.
Molecular Therapy - Oncolytics
-
SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells
Authors: J Wang, G Yang, X Wang, Z Wen, L Shuai, J Luo, C Wang, Z Sun, R Liu, J Ge, X He, R Hua, X Wang, X Yang, W Chen, G Zhong, Z Bu
Cell Discovery, 2021-12-14;7(1):119.
Species: Human, Primate - C. aethiops
Sample Types: Whole Cells
Applications: Neutralization -
Interleukin-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis
Authors: JE Miller, H Lingegowda, LK Symons, O Bougie, SL Young, BA Lessey, M Koti, C Tayade
JCI Insight, 2021-12-08;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
Authors: Zhiguang Xiao, Stephen R. Hammes
iScience
-
LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy
Authors: P Li, Q Li, N Biswas, H Xin, T Diemer, L Liu, L Perez Guti, G Paternostr, C Piermarocc, S Domanskyi, RK Wang, N Ferrara
Embo Molecular Medicine, 2021-11-15;0(0):e14511.
Species: Bovine
Sample Types: Whole Cells
Applications: Neutralization Control -
Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics
Authors: D Olmeda, D Cerezo-Wal, C Mucientes, TG Calvo, E Cañón, D Alonso-Cur, N Ibarz, J Muñoz, JL Rodriguez-, P Ortiz-Rome, S Ortega, MS Soengas
Embo Molecular Medicine, 2021-11-11;0(0):e12924.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Incorporation of apolipoprotein E into HBV-HCV subviral envelope particles to improve the hepatitis vaccine strategy
Authors: E Gomez-Esco, J Burlaud-Ga, C Visdeloup, ARE Silva, P Coutant, P Roingeard, E Beaumont
Scientific Reports, 2021-11-08;11(1):21856.
Species: Hamster
Sample Types: Cell Lysates
Applications: Co-Immunoprecipitation -
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Authors: Zhang HF, Hughes CS, Li W et al.
Cancer Discovery
-
PERK signaling through C/EBPdelta contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells
Authors: N Sheshadri, DK Poria, S Sharan, Y Hu, C Yan, VN Koparde, K Balamuruga, E Sterneck
Cell Death & Disease, 2021-11-01;12(11):1038.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model
Authors: KM Lugo-Cintr, JM Ayuso, M Humayun, MM Gong, SC Kerr, SM Ponik, PM Harari, M Virumbrale, DJ Beebe
EBioMedicine, 2021-10-18;73(0):103634.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Authors: Haichuan H, Zofia P, Patricia H et al.
Cancer Cell.
-
PLCgamma2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages
Authors: J Obst, HL Hall-Rober, TB Smith, M Kreuzer, L Magno, E Di Daniel, JB Davis, E Mead
Scientific Reports, 2021-10-06;11(1):19842.
Species: Human
Sample Types: Whole Cells
Applications: Control -
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
Authors: Y Wang, Y Zhang, S Zhang, B Kim, VL Hull, J Xu, P Prabhu, M Gregory, V Martinez-C, X Zhan, W Deng, F Guo
Cell Reports, 2021-10-05;37(1):109695.
Species: Mouse
Sample Types: Recombinant Protein
Applications: Immunoprecipitation -
Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer
Authors: Theo Z. Hirsch, Jill Pilet, Guillaume Morcrette, Amélie Roehrig, Benedict J.E. Monteiro, Laura Molina et al.
Cancer Discovery
-
Activated macrophages promote invasion by early colorectal cancer via an interleukin 1 beta ‐serum amyloid A1 axis
Authors: Gota Sudo, Hironori Aoki, Eiichiro Yamamoto, Akira Takasawa, Takeshi Niinuma, Ayano Yoshido et al.
Cancer Science
-
The inflammatory signalling mediator TAK1 mediates lymphocyte recruitment to lipopolysaccharide-activated murine mesenchymal stem cells through interleukin-6
Authors: Beatrice Oelze, Kirsten Elger, Patrik Schadzek, Laura Burmeister, Anika Hamm, Sandra Laggies et al.
Molecular and Cellular Biochemistry
-
Targeting hepatocyte growth factor in epithelial–stromal interactions in an in vitro experimental model of human periodontitis
Authors: Yoko Yamaguchi, Akira Saito, Masafumi Horie, Akira Aoki, Patrick Micke, Mitsuhiro Ohshima et al.
Odontology
-
CXCL13 expression in mouse 4T1 breast cancer microenvironment elicits antitumor immune response by regulating immune cell infiltration
Authors: Qizhi Ma, Yue Chen, Qing Qin, Fuchun Guo, Yong-sheng Wang, Dan Li
Precision Clinical Medicine
-
Obesity-associated leptin promotes chemoresistance in colorectal cancer through YAP-dependent AXL upregulation
Authors: YC Chen, CY Chien, CC Hsu, CH Lee, YT Chou, SG Shiah, SY Liu, CY Yen, AC Hsieh, M Wabitsch, YS Shieh
American journal of cancer research, 2021-09-15;11(9):4220-4240.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Osteocyte Wnt/beta-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
Authors: E Jackson, N Lara-Casti, MP Akhter, M Dallas, JM Scott, T Ganesh, ML Johnson
Bone Reports, 2021-09-14;15(0):101129.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC Control -
Metallothionein 2A Expression in Cancer-Associated Fibroblasts and Cancer Cells Promotes Esophageal Squamous Cell Carcinoma Progression
Authors: M Shimizu, YI Koma, H Sakamoto, S Tsukamoto, Y Kitamura, S Urakami, K Tanigawa, T Kodama, N Higashino, M Nishio, M Shigeoka, Y Kakeji, H Yokozaki
Cancers, 2021-09-10;13(18):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
Authors: K Wu, J Feng, F Lyu, F Xing, S Sharma, Y Liu, SY Wu, D Zhao, A Tyagi, RP Deshpande, X Pei, MG Ruiz, H Takahashi, S Tsuzuki, T Kimura, YY Mo, Y Shiozawa, R Singh, K Watabe
Nature Communications, 2021-08-31;12(1):5196.
Species: Human
Sample Types:
Applications: Binding Assay -
Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease
Authors: Daniela Regensburger, Clara Tenkerian, Victoria Pürzer, Benjamin Schmid, Thomas Wohlfahrt, Iris Stolzer et al.
Inflammatory Bowel Diseases
-
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
Authors: P Szodoray, TK Andersen, J Heinzelbec, JF Imbery, PC Huszthy, SM Stanford, B Bogen, OB Landsverk, N Bottini, A Tveita, LA Munthe, B Nakken
Cell Reports, 2021-08-10;36(6):109525.
Species: Human
Sample Types: Cell Lysates
Applications: Isotype Control -
HO‑1 knockdown upregulates the expression of VCAM‑1 to induce neutrophil recruitment during renal ischemia‑reperfusion injury
Authors: Yecheng He, Huadong Li, Juan Yao, Hua Zhong, Yanbin Kuang, Xin Li et al.
International Journal of Molecular Medicine
-
Extracellular CIRP Activates the IL-6R alpha /STAT3/Cdk5 Pathway in Neurons
Authors: Archna Sharma, Max Brenner, Asha Jacob, Philippe Marambaud, Ping Wang
Molecular Neurobiology
-
Investigation of fascin1, a marker of mature dendritic cells, reveals a New role for IL-6 signaling in CCR7-mediated chemotaxis.
Authors: Fumio Matsumura, Robin Polz, Sukhwinder Singh, Aya Matsumura, Jürgen Scheller, Shigeko Yamashiro
The Journal of Immunology
-
Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein
Authors: Jillian M. DiMuzio, Baron C. Heimbach, Raymond J. Howanski, John P. Dowling, Nirja B. Patel, Noeleya Henriquez et al.
Vaccine: X
-
Local administration of anti-hepatocyte growth factor-neutralizing antibody reverts naturally occurring periodontitis
Authors: Y Yamaguchi, M Ohshima
Journal of oral biosciences, 2021-07-22;0(0):.
Species: Human
Sample Types: Collagen gel
Applications: Functional Assay Control -
SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
Authors: Chihiro Motozono, Mako Toyoda, Jiri Zahradnik, Akatsuki Saito, Hesham Nasser, Toong Seng Tan et al.
Cell Host & Microbe
-
Toxoplasma gondii Matrix Antigen 1 Is a Secreted Immunomodulatory Effector
Authors: Tadakimi Tomita, Debanjan Mukhopadhyay, Bing Han, Rama Yakubu, Vincent Tu, Joshua Mayoral et al.
mBio
-
CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype
Authors: C Xie, F Ye, N Zhang, Y Huang, Y Pan, X Xie
Journal of Cellular and Molecular Medicine, 2021-06-29;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture
Authors: P Lian, S Braber, S Varasteh, HJ Wichers, G Folkerts
Scientific Reports, 2021-06-23;11(1):13186.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair
Authors: GHP Ngo, JW Grimstead, DM Baird
Nature Communications, 2021-06-22;12(1):3849.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ChIP Control -
TNFalpha-Induced LDL Cholesterol Accumulation Involve Elevated LDLR Cell Surface Levels and SR-B1 Downregulation in Human Arterial Endothelial Cells
Authors: EU Okoro
International Journal of Molecular Sciences, 2021-06-09;22(12):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Testicular germ cell-specific lncRNA, Teshl, is required for complete expression of Y chromosome genes and a normal offspring sex ratio
Authors: SH Hong, G Han, SJ Lee, J Cocquet, C Cho
Science Advances, 2021-06-09;7(24):.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: ChIP, RNA immunoprecipitation -
ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin
Authors: Lynda J. Partridge, Lucy Urwin, Martin J. H. Nicklin, David C. James, Luke R. Green, Peter N. Monk
Cells
-
Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence
Authors: V Grotheer, N Skrynecki, L Oezel, J Grassmann, J Windolf, CV Suschek
Scientific Reports, 2021-06-07;11(1):11968.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
ADAM17 Boosts Cholesterol Efflux and Downstream Effects of High-Density Lipoprotein on Inflammatory Pathways in Macrophages
Authors: Vishal Kothari, Jingjing Tang, Yi He, Farah Kramer, Jenny E. Kanter, Karin E. Bornfeldt
Arteriosclerosis, Thrombosis, and Vascular Biology
-
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
Authors: Hani Harb, Mehdi Benamar, Peggy S. Lai, Paola Contini, Jason W. Griffith, Elena Crestani et al.
Immunity
-
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
Authors: S Ghosh, NB Nataraj, A Noronha, S Patkar, A Sekar, S Mukherjee, S Winograd-K, L Kramarski, A Verma, M Lindzen, DD Garcia, J Green, G Eisenberg, H Gil-Henn, A Basu, Y Lender, S Weiss, M Oren, M Lotem, B Geiger, E Ruppin, Y Yarden
Cell Reports, 2021-05-25;35(8):109181.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation, Western Blot -
Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages
Authors: F Wanke, S Gutbier, A Rümmelin, M Steinberg, LD Hughes, M Koenen, J Komuczki, D Regan-Komi, S Wagage, J Hesselmann, R Thoma, D Brugger, T Christopei, H Wang, F Point, R Hallet, S Ghosh, CV Rothlin, C Patsch, B Geering
Cell Death & Disease, 2021-05-25;12(6):538.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Heroin Seeking and Extinction From Seeking Activate Matrix Metalloproteinases at Synapses on Distinct Subpopulations of Accumbens Cells
Authors: Vivian C. Chioma, Anna Kruyer, Ana-Clara Bobadilla, Ariana Angelis, Zachary Ellison, Ritchy Hodebourg et al.
Biological Psychiatry
-
SMAD-specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis
Authors: Mengjun Ma, Wen Yang, Zhaopeng Cai, Peng Wang, Hongyu Li, Rujia Mi et al.
Stem Cells
-
Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation
Authors: Daniela C. Ivan, Sabrina Walthert, Giuseppe Locatelli
Frontiers in Immunology
-
MicroLet-7b Regulates Neutrophil Function and Dampens Neutrophilic Inflammation by Suppressing the Canonical TLR4/NF-kappa B Pathway
Authors: Binzhen Chen, Jia Han, Shaoheng Chen, Rufeng Xie, Jie Yang, Tongming Zhou et al.
Frontiers in Immunology
-
Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification
Authors: Tao Yu, Jianguo Zhang, Wei Zhu, Xiao Wang, Yun Bai, Bin Feng et al.
Bone Research
-
Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis
Authors: Simon D. Fraser, Michael G. Crooks, Paul M. Kaye, Simon P. Hart
ERJ Open Research
-
RGS10 physically and functionally interacts with STIM2 and requires store-operated calcium entry to regulate proinflammatory gene expression in microglia
Authors: M Wendimu, M Alqinyah, S Vella, P Dean, F Almutairi, RD Rivera, S Rayatpishe, J Wohlschleg, S Moreno, SB Hooks
Cellular Signalling, 2021-03-09;0(0):109974.
Species: Mouse
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface
Authors: A Chu, SY Kok, J Tsui, MC Lin, B Aguirre, M Wadehra
Journal of reproductive immunology, 2021-03-09;145(0):103309.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Helicobacter pylori-induced Rev-erb&alpha fosters gastric bacteria colonization by impairing host innate and adaptive defense
Authors: FY Mao, YP Lv, CJ Hao, YS Teng, YG Liu, P Cheng, SM Yang, W Chen, T Liu, QM Zou, R Xie, JY Xu, Y Zhuang
Cellular and Molecular Gastroenterology and Hepatology, 2021-03-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
PAI-1 derived from cancer-associated fibroblasts in esophageal squamous cell carcinoma promotes the invasion of cancer cells and the migration of macrophages
Authors: Hiroki Sakamoto, Yu-ichiro Koma, Nobuhide Higashino, Takayuki Kodama, Kohei Tanigawa, Masaki Shimizu et al.
Laboratory Investigation
-
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
Authors: Yohei Takahashi, Hidenori Wake, Masakiyo Sakaguchi, Yukinori Yoshii, Kiyoshi Teshigawara, Dengli Wang et al.
The Journal of Immunology
-
An Inflammatory Loop Between Spleen-Derived Myeloid Cells and CD4+ T Cells Leads to Accumulation of Long-Lived Plasma Cells That Exacerbates Lupus Autoimmunity
Authors: Eunkyeong Jang, Somi Cho, Sungjin Pyo, Jin-Wu Nam, Jeehee Youn
Frontiers in Immunology
-
Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer
Authors: JJ McGuire, JS Frieling, CH Lo, T Li, A Muhammad, HR Lawrence, NJ Lawrence, LM Cook, CC Lynch
Nature Communications, 2021-02-01;12(1):723.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer
Authors: Jing Chen, Hong-Wei Sun, Yan-Yan Yang, Hai-Tian Chen, Xing-Juan Yu, Wen-Chao Wu et al.
Signal Transduction and Targeted Therapy
-
Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy
Authors: RV Broad, SJ Jones, MC Teske, LM Wastall, AM Hanby, JL Thorne, TA Hughes
British Journal of Cancer, 2021-01-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Design and Functional Validation of a Mutant Variant of the LncRNA HOTAIR to Counteract Snail Function in Epithelial-to-Mesenchymal Transition
Authors: Battistelli C, Garbo S, Riccioni V et al.
Cancer Research
-
Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes
Authors: Z Wang, Y Wang, N Bradbury, C Gonzales B, B Schnabl, A Di Nardo
Scientific Reports, 2020-12-10;10(1):21732.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras
Authors: Szu-Wei Lee, Cosimo Commisso
Biochemical and Biophysical Research Communications
-
Fibroblast-derived IL-33 facilitates breast cancer metastasis by modifying the immune microenvironment and driving type-2 immunity
Authors: Ophir Shani, Tatiana Vorobyov, Lea Monteran, Dor Lavie, Noam Cohen, Yael Raz et al.
Cancer Research
-
Prevention of CaCl2-induced aortic inflammation and subsequent aneurysm formation by the CCL3-CCR5 axis
Authors: Y Ishida, Y Kuninaka, M Nosaka, A Kimura, A Taruya, M Furuta, N Mukaida, T Kondo
Nat Commun, 2020-11-25;11(1):5994.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
TNF-&alpha-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats
Authors: S Ren, L Breuillaud, W Yao, T Yin, KA Norris, SP Zehntner, L D'Adamio
The Journal of Biological Chemistry, 2020-11-21;296(0):100089.
Species: Rat, Transgenic Rat
Sample Types: Whole Tissue
Applications: Neutralization Control -
Immortalized stem cell-derived hepatocyte-like cells: An alternative model for studying dengue pathogenesis and therapy
Authors: K Kongmanas, N Punyadee, K Wasuworawo, A Songjaeng, T Prommool, Y Pewkliang, S Manocheewa, S Thiemmeca, K Sa-Ngiamsu, C Puttikhunt, KF Faull, S Hongeng, P Avirutnan
PLoS Negl Trop Dis, 2020-11-20;14(11):e0008835.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Synthetic lethality between MyD88 loss and mutations in Wnt/&beta-catenin pathway in intestinal tumor epithelial cells
Authors: R Kajino-Sak, T Fujishita, MM Taketo, M Aoki
Oncogene, 2020-11-12;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Low concentration IL-1 beta promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro
Authors: Andrew T. Templin, Mahnaz Mellati, Daniel T. Meier, Nathalie Esser, Meghan F. Hogan, Joseph J. Castillo et al.
Diabetologia
-
Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
J Neuroinflammation, 2020-10-29;17(1):324.
Species: Mouse
Sample Types: In Vivo
Applications: Functional Assay -
&alpha2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline
Authors: E Kawashita, K Ishihara, H Miyaji, Y Tanishima, A Kiriyama, O Matsuo, S Akiba
Mol Brain, 2020-10-15;13(1):140.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner
Authors: YY Liang, XB Deng, XT Lin, LL Jiang, XT Huang, ZW Mo, YW Yuan, MT Teh
Cell Death Dis, 2020-10-14;11(10):855.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23
Authors: PL Mulcrone, SKE Edwards, DN Petrusca, LS Haneline, J Delgado-Ca, GD Roodman
Sci Rep, 2020-10-14;10(1):17319.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis
Authors: CH Pai, SR Lin, CH Liu, SY Pan, H Hsu, YT Chen, CT Yen, IS Yu, HL Wu, SL Lin, SW Lin
Sci Rep, 2020-10-08;10(1):16772.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: ICC, Isotype Control -
Pharmacological Modulation of Blood–Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions
Authors: Dina Sikpa, Lisa Whittingstall, Martin Savard, Réjean Lebel, Jérôme Côté, Stephen McManus et al.
Pharmaceuticals (Basel)
-
The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/&beta-catenin signaling pathway
Authors: R Deng, C Zuo, Y Li, B Xue, Z Xun, Y Guo, X Wang, Y Xu, R Tian, S Chen, Q Liu, J Chen, J Wang, X Huang, H Li, M Guo, X Wang, M Yang, Z Wu, J Wang, J Ma, J Hu, G Li, S Tang, Z Tu, H Ji, H Zhu
Cell. Mol. Immunol., 2020-09-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
The c‑Jun signaling pathway has a protective effect on nucleus pulposus cells in patients with intervertebral disc degeneration
Authors: Ming Lei, Kun Wang, Shuai Li, Kangcheng Zhao, Wenbin Hua, Xinghuo Wu et al.
Experimental and Therapeutic Medicine
-
Characterization of zika virus infection of human fetal cardiac mesenchymal stromal cells
Authors: F Rossi, B Josey, EC Sayitoglu, R Potens, T Sultu, AD Duru, V Beljanski
PLoS ONE, 2020-09-17;15(9):e0239238.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner
Authors: QF Zhang, J Li, K Jiang, R Wang, JL Ge, H Yang, SJ Liu, LT Jia, L Wang, BL Chen
Theranostics, 2020-08-25;10(23):10619-10633.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris
Authors: M Bruno, S Kersten, JM Bain, M Jaeger, D Rosati, MD Kruppa, DW Lowman, PJ Rice, B Graves, Z Ma, YN Jiao, A Chowdhary, G Renieris, FL van de Vee, BJ Kullberg, EJ Giamarello, A Hoischen, NAR Gow, AJP Brown, JF Meis, DL Williams, MG Netea
Nat Microbiol, 2020-08-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Glutamine deprivation alters the origin and function of cancer cell exosomes
Authors: Shih‐Jung Fan, Benjamin Kroeger, Pauline P Marie, Esther M Bridges, John D Mason, Kristie McCormick et al.
The EMBO Journal
-
Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines
Authors: JS Yi, SK Perla, LE Enyenihi, AM Bennett
JCI Insight, 2020-08-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity
Authors: A Filiberti, GB Gmyrek, ML Montgomery, R Sallack, DJJ Carr
Invest. Ophthalmol. Vis. Sci., 2020-08-03;61(10):24.
Species: Mouse, Transgenic Mouse
Sample Types: In Vivo
Applications: In Vivo -
Mediation of Cartilage Matrix Degeneration and Fibrillation by Decorin in Post‐traumatic Osteoarthritis
Authors: Qing Li, Biao Han, Chao Wang, Wei Tong, Yulong Wei, Wei‐Ju Tseng et al.
Arthritis & Rheumatology
-
SNAIL Promotes Metastatic Behavior of Rhabdomyosarcoma by Increasing EZRIN and AKT Expression and Regulating MicroRNA Networks
Authors: Klaudia Skrzypek, Marta Kot, Paweł Konieczny, Artur Nieszporek, Anna Kusienicka, Małgorzata Lasota et al.
Cancers (Basel)
-
Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis
Authors: B Moon, J Lee, SA Lee, C Min, H Moon, D Kim, S Yang, H Moon, J Jeon, YE Joo, D Park
Cells, 2020-07-06;9(7):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-alpha levels
Authors: Siqiang Ren, Wen Yao, Marc D Tambini, Tao Yin, Kelly A Norris, Luciano D'Adamio
eLife
-
Secretome Analysis of Mesenchymal Stem Cell Factors Fostering Oligodendroglial Differentiation of Neural Stem Cells In Vivo
Authors: Iria Samper Agrelo, Jessica Schira-Heinen, Felix Beyer, Janos Groh, Christine Bütermann, Veronica Estrada et al.
International Journal of Molecular Sciences
-
IGF1R is an entry receptor for respiratory syncytial virus
Authors: CD Griffiths, LM Bilawchuk, JE McDonough, KC Jamieson, F Elawar, Y Cen, W Duan, C Lin, H Song, JL Casanova, S Ogg, LD Jensen, B Thienpont, A Kumar, TC Hobman, D Proud, TJ Moraes, DJ Marchant
Nature, 2020-06-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways
Authors: T Kodama, YI Koma, N Arai, A Kido, N Urakawa, M Nishio, M Shigeoka, H Yokozaki
Lab. Invest., 2020-05-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues
Authors: A Klingler, D Regensburg, C Tenkerian, N Britzen-La, A Hartmann, M Stürzl, E Naschberge
PLoS ONE, 2020-05-21;15(5):e0233422.
Species: Human
Sample Types: Whole Tissue
Applications: Isotype Control -
Positive Effect of Gushukang on Type-H Vessel and Bone Formation
Authors: Wantao Li, Xiaoqing Zhou, Tiejian Jiang, Hongbo He, Ting Wen
Frontiers in Cell and Developmental Biology
-
Platelets Fuel the Inflammasome Activation of Innate Immune Cells
Authors: V Rolfes, LS Ribeiro, I Hawwari, L Böttcher, N Rosero, S Maasewerd, MLS Santos, T Próchnicki, CMS Silva, CWS Wanderley, M Rothe, SV Schmidt, HJ Stunden, D Bertheloot, MN Rivas, CJ Fontes, LH Carvalho, FQ Cunha, E Latz, M Arditi, BS Franklin
Cell Rep, 2020-05-12;31(6):107615.
Species: Human
Sample Types:
Applications: Control -
Nerve growth factor receptor role on rabbit sperm storage
Authors: C Castellini, S Mattioli, AD Bosco, E Cotozzolo, A Cartoni Ma, M Rende, AM Stabile, A Pistilli
Theriogenology, 2020-05-11;153(0):54-61.
Species: Rabbit
Sample Types: Whole Cells
Applications: Flow Cytometry -
Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier
Authors: J Kim, B Alejandro, M Hetman, EM Hattab, J Joiner, H Schroten, H Ishikawa, DH Chung
PLoS Pathog., 2020-05-01;16(5):e1008204.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma
Authors: D Bararia, JA Hildebrand, S Stolz, S Haebe, S Alig, CP Trevisani, F Osorio-Bar, MD Bartoschek, M Mentz, A Pastore, E Gaitzsch, M Heide, V Jurinovic, K Rautter, J Gunawardan, MB Sabdia, M Szczepanow, J Richter, W Klapper, A Louissaint, C Ludwig, S Bultmann, H Leonhardt, S Eustermann, KP Hopfner, W Hiddemann, M von Bergwe, C Steidl, R Kridel, JWD Tobin, MK Gandhi, DM Weinstock, M Schmidt-Su, MB Sárosi, M Rudelius, V Passerini, J Mautner, O Weigert
Cell Rep, 2020-04-23;31(5):107522.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Mouse models of neutropenia reveal progenitor-stage-specific defects
Authors: DE Muench, A Olsson, K Ferchen, G Pham, RA Serafin, S Chutipongt, P Dwivedi, B Song, S Hay, K Chetal, LR Trump-Durb, J Mookerjee-, K Zhang, JC Yu, C Lutzko, KC Myers, KL Nazor, KD Greis, DJ Kappes, SS Way, N Salomonis, HL Grimes
Nature, 2020-04-22;582(7810):109-114.
Species: Human
Sample Types: Whole Tissue
Applications: IHC Control -
RETRACTED: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
Authors: Ken Morita, Shuning He, Radosław P. Nowak, Jinhua Wang, Mark W. Zimmerman, Cong Fu et al.
Cell
-
Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21
Authors: L Mercurio, D Lulli, F Mascia, E Dellambra, C Scarponi, M Morelli, C Valente, ML Carbone, S Pallotta, G Girolomoni, C Albanesi, S Pastore, S Madonna
Aging (Albany NY), 2020-04-17;12(8):6823-6851.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization -
Assessment of Thrombotic and Bleeding Tendency in Two Mouse Models of Chronic Kidney Disease: Adenine-Diet and 5/6th Nephrectomy
Authors: Camélia Makhloufi, Lydie Crescence, Roxane Darbousset, Nathalie McKay, Ziad A. Massy, Christophe Dubois et al.
TH Open
-
High circulating elafin levels are associated with Crohn's disease-associated intestinal strictures
Authors: J Wang, C Ortiz, L Fontenot, Y Xie, W Ho, SA Mattai, DQ Shih, HW Koon
PLoS ONE, 2020-04-14;15(4):e0231796.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4
Authors: K Kuronuma, A Yokoi, T Fukuoka, M Miyata, A Maekawa, S Tanaka, L Matsubara, C Goto, M Matsuo, HW Han, M Tsuruta, H Murata, H Okamoto, N Hasegawa, S Asano, M Ito
Heliyon, 2020-04-12;6(4):e03743.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
The critical role of MMP14 in adipose tissue remodeling during obesity
Authors: X Li, Y Zhao, C Chen, L Yang, HH Lee, Z Wang, N Zhang, MG Kolonin, Z An, X Ge, PE Scherer, K Sun
Mol. Cell. Biol., 2020-03-30;0(0):.
Species: Human
Sample Types: Chromatin
Applications: ChIP (chromatin immunoprecipit -
Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress
Authors: BR Kim, BJ Kim, YH Kook, BJ Kim
PLoS Pathog., 2020-03-25;16(3):e1008294.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma
Authors: N Muthalagu, T Monteverde, X Raffo-Irao, R Wiesheu, D Whyte, A Hedley, S Laing, B Kruspig, R Upstill-Go, R Shaw, S Neidler, C Rink, SA Karim, K Gyuraszova, C Nixon, W Clark, AV Biankin, LM Carlin, SB Coffelt, OJ Sansom, JP Morton, DJ Murphy
Cancer Discov, 2020-03-21;0(0):.
Species: Mouse
Sample Types:
Applications: In Vivo -
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
Authors: M Pein, J Insua-Rodr, T Hongu, A Riedel, J Meier, L Wiedmann, K Decker, MAG Essers, HP Sinn, S Spaich, M Sütterlin, A Schneeweis, A Trumpp, T Oskarsson
Nat Commun, 2020-03-20;11(1):1494.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture -
Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation
Authors: M Zhou, M Aziz, NL Denning, HT Yen, G Ma, P Wang
JCI Insight, 2020-03-12;0(0):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Control, Flow Cytometry, ICC -
IL-15R alpha membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling
Authors: Agnès Quéméner, Sébastien Morisseau, Rui P. Sousa, Kilian Trillet, Mike Maillasson, Isabelle Leray et al.
Journal of Cell Science
-
Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation
Authors: Mi Yang, Chang‐Jun Li, Ye Xiao, Qi Guo, Yan Huang, Tian Su et al.
Cell Proliferation
-
AREG mediates the epithelial?mesenchymal transition in pancreatic cancer cells via the EGFR/ERK/NF?&kappaB signalling pathway
Authors: L Wang, L Wang, H Zhang, J Lu, Z Zhang, H Wu, Z Liang
Oncol. Rep., 2020-02-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin in?ammation
Authors: Z Wang, H Zhou, H Zheng, X Zhou, G Shen, X Teng, X Liu, J Zhang, X Wei, Z Hu, F Zeng, Y Hu, J Hu, X Wang, S Chen, J Cheng, C Zhang, Y Gui, S Zou, Y Hao, Q Zhao, W Wu, Y Zhou, K Cui, N Huang, Y Wei, W Li, J Li
Autophagy, 2020-02-16;0(0):1-24.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Systemic HIV and SIV latency reversal via non-canonical NF-kappaB signalling in vivo
Authors: CC Nixon, M Mavigner, GC Sampey, AD Brooks, RA Spagnuolo, DM Irlbeck, C Mattingly, PT Ho, N Schoof, CG Cammon, GK Tharp, M Kanke, Z Wang, RA Cleary, AA Upadhyay, C De, SR Wills, SD Falcinelli, C Galardi, H Walum, NJ Schramm, J Deutsch, JD Lifson, CM Fennessey, BF Keele, S Jean, S Maguire, B Liao, EP Browne, RG Ferris, JH Brehm, D Favre, TH Vanderford, SE Bosinger, CD Jones, JP Routy, NM Archin, DM Margolis, A Wahl, RM Dunham, G Silvestri, A Chahroudi, JV Garcia
Nature, 2020-01-22;578(7793):160-165.
Species: Human
Sample Types: Whole Tissue
Applications: IHC Control -
Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization
Authors: CD Lemke-Milt, SE Blackwell, C Yin, AE Krug, AJ Morris, AM Krieg, GJ Weiner
J. Immunol., 2020-01-17;204(5):1386-1394.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
TNF-&alpha-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H �rats
Authors: S Ren, L Breuillaud, W Yao, T Yin, KA Norris, SP Zehntner, L D'Adamio
J Biol Chem, 2020-01-01;0(0):.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC -
TGF-beta 3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway
Authors: Yun Zhang, Hong-Mei Tang, Chun-Feng Liu, Xie-Fang Yuan, Xiao-Yun Wang, Ning Ma et al.
Mediators of Inflammation
-
Ex vivo culture of lesional psoriasis skin for pharmacological testing
Authors: ML Tiirikaine, A Woetmann, H Norsgaard, LF Santamaria, P Lovato
J. Dermatol. Sci., 2019-12-27;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Tissue Culture -
Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology
Authors: A Mendsaikha, I Tooyama, JP Bellier, GE Serrano, LI Sue, LF Lue, TG Beach, DG Walker
Acta Neuropathol Commun, 2019-12-21;7(1):215.
Species: Human
Sample Types: Tissue Homogenates
Applications: Western Blot -
Sevoflurane promotes the proliferation of HUVECs by activating VEGF signaling
Authors: Zengtao Wang, Cui Wu, Min Zhang, Aiping Dong, Ruibin Niu, Jie Zhang
Experimental and Therapeutic Medicine
-
Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice
Authors: Sergio M. Borghi, Victor Fattori, Felipe A. Pinho-Ribeiro, Talita P. Domiciano, Milena M. Miranda-Sapla, Tiago H. Zaninelli et al.
Journal of Neuroinflammation
-
Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation
Authors: Eugene Kim, Ming Jiang, Huachao Huang, Yongchun Zhang, Natalie Tjota, Xia Gao et al.
Developmental Cell
-
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons
Authors: Max Koppers, Roberta Cagnetta, Toshiaki Shigeoka, Lucia CS Wunderlich, Pedro Vallejo-Ramirez, Julie Qiaojin Lin et al.
eLife
-
Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model
Authors: Hector R. Wong, J. Timothy Caldwell, Natalie Z. Cvijanovich, Scott L. Weiss, Julie C. Fitzgerald, Michael T. Bigham et al.
Science Translational Medicine
-
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
Authors: V Frodermann, D Rohde, G Courties, N Severe, MJ Schloss, H Amatullah, CS McAlpine, S Cremer, FF Hoyer, F Ji, ID van Koever, F Herisson, L Honold, GS Masson, S Zhang, J Grune, Y Iwamoto, SP Schmidt, GR Wojtkiewic, IH Lee, K Gustafsson, G Pasterkamp, SCA de Jager, RI Sadreyev, J MacFadyen, P Libby, P Ridker, DT Scadden, K Naxerova, KL Jeffrey, FK Swirski, M Nahrendorf
Nat. Med., 2019-11-07;25(11):1761-1771.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
A FUNCTIONAL ROLE OF GAS6/TAM IN NON-ALCOHOLIC STEATOHEPATITIS PROGRESSION IMPLICATES AXL AS THERAPEUTIC TARGET
Authors: A Tutusaus, E de Gregori, B Cucarull, H Cristóbal, C Aresté, I Graupera, M Coll, A Colell, G Gausdal, JB Lorens, P García de, A Morales, M Marí
Cell Mol Gastroenterol Hepatol, 2019-11-02;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation
Authors: Shuvasree SenGupta, Madhavi J Rane, Silvia M Uriarte, Cassandra Woolley, Thomas C Mitchell
Innate Immunity
-
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126
Authors: Md. Riaj Mahamud, Xin Geng, Yen-Chun Ho, Boksik Cha, Yuenhee Kim, Jing Ma et al.
Development
-
Uterine SOX17: a key player in human endometrial receptivity and embryo implantation
Authors: S Kinnear, LA Salamonsen, M Francois, V Harley, J Evans
Sci Rep, 2019-10-29;9(1):15495.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
Nature, 2019-10-23;574(7779):553-558.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps
Authors: N Ogasawara, JA Poposki, AI Klingler, BK Tan, KE Hulse, WW Stevens, AT Peters, LC Grammer, KC Welch, SS Smith, DB Conley, JR Raviv, P Soroosh, KI Takano, T Himi, RC Kern, RP Schleimer, A Kato
Mucosal Immunol, 2019-10-22;13(1):86-95.
Species: Human
Sample Types: nasal ployps-lymphoid cells
Applications: Cell Culture -
Responses of primary osteoblasts and osteoclasts from hemizygous beta-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3
Authors: N Charoenpha, R Aeimlapa, S Sooksawanw, J Thongbunch, J Teerapornp, S Svasti, K Wongdee
Sci Rep, 2019-09-27;9(1):13963.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Sustained intraocular vascular endothelial growth factor neutralisation does not affect retinal and choroidal vasculature in Ins2Akita diabetic mice
Authors: Judith Lechner, Jose R Hombrebueno, Edoardo Pedrini, Mei Chen, Heping Xu
Diabetes and Vascular Disease Research
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Type 2 innate lymphoid cells participate in IL‑33‑stimulated Th2‑associated immune response in chronic obstructive pulmonary disease
Authors: Min Jiang, Simin Tao, Shaohua Zhang, Jing Wang, Fengbo Zhang, Fengsen Li et al.
Experimental and Therapeutic Medicine
-
Aminoguanidine reduces diabetes‑associated cardiac fibrosis
Authors: Fernando Magdaleno, Chuck Christopher Blajszczak, Claudia Lisette Charles‑Ni�o, Alma Marlene Guadr�n‑Llanos, Alan Omar V�zquez‑�lvarez, Alejandra Guillermina Miranda‑D�az et al.
Experimental and Therapeutic Medicine
-
Longitudinal Molecular Magnetic Resonance Imaging of Endothelial Activation after Severe Traumatic Brain Injury
Authors: Gloria Vegliante, Daniele Tolomeo, Antoine Drieu, Marina Rubio, Edoardo Micotti, Federico Moro et al.
Journal of Clinical Medicine
-
Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice
Authors: A Carestia, HA Mena, CM Olexen, JM Ortiz Wilc, S Negrotto, AE Errasti, RM Gómez, CN Jenne, EA Carrera Si, M Schattner
Cell Rep, 2019-07-23;28(4):896-908.e5.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells
Authors: DP Strange, B Jiyarom, N Pourhabibi, X Xie, C Baker, H Sadri-Arde, PY Shi, S Verma
MBio, 2019-07-16;10(4):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Statins can suppress dendritic cell-mediated Th2 responses through the repression of OX40-ligand and CCL17 expression
Authors: N Inagaki-Ka, T Ito, M Inaba, Y Azuma, A Tanaka, PTX Vien, K Kibata, A Satake, S Nomura
Eur. J. Immunol., 2019-07-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain
Authors: LJ Zhou, J Peng, YN Xu, WJ Zeng, J Zhang, X Wei, CL Mai, ZJ Lin, Y Liu, M Murugan, UB Eyo, AD Umpierre, WJ Xin, T Chen, M Li, H Wang, JR Richardson, Z Tan, XG Liu, LJ Wu
Cell Rep, 2019-06-25;27(13):3844-3859.e6.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain
Authors: M Richner, LT Pallesen, M Ulrichsen, ET Poulsen, TH Holm, H Login, A Castonguay, LE Lorenzo, NP Gonçalves, OM Andersen, K Lykke-Hart, JJ Enghild, LCB Rønn, IJ Malik, Y De Koninck, OJ Bjerrum, CB Vægter, A Nykjær
Sci Adv, 2019-06-19;5(6):eaav9946.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens
Authors: R Hatano, T Yamada, H Madokoro, H Otsuka, E Komiya, T Itoh, Y Narita, S Iwata, H Yamazaki, S Matsuoka, NH Dang, K Ohnuma, C Morimoto
PLoS ONE, 2019-06-13;14(6):e0218330.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration
Authors: A Vaquié, A Sauvain, M Duman, G Nocera, B Egger, F Meyenhofer, L Falquet, L Bartesaghi, R Chrast, CM Lamy, S Bang, SR Lee, NL Jeon, S Ruff, C Jacob
Cell Rep, 2019-06-11;27(11):3152-3166.e7.
Species: Rat
Sample Types: Whole Cell
Applications: Neutralization -
Aberrantly elevated Bmi1 promotes cervical cancer tumorigenicity and tumor sphere formation via enhanced transcriptional regulation of Sox2 genes
Authors: R Xu, L Chen, WT Yang
Oncol. Rep., 2019-06-06;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis
Authors: C Miyabe, Y Miyabe, L Moreno, J Lian, RA Rahimi, NN Miura, N Ohno, Y Iwakura, T Kawakami, AD Luster
J. Clin. Invest., 2019-06-06;130(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection
Authors: A Zychlinsky, M Rousseau, L Lacerda Ma, T Canton, CR Consiglio, ML Albert, M Fontes, D Duffy, MA Ingersoll
JCI Insight, 2019-05-30;5(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization
Authors: J Cao, R Yang, TE Smith, S Evans, GW McCollum, SC Pomerantz, T Petley, IR Harris, JS Penn
Mol Ther Methods Clin Dev, 2019-05-22;14(0):37-46.
Species: Human
Sample Types: Recombinant Protein
Applications: Western Blot -
IL-4R?-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
Authors: LK Dubey, B Ludewig, SA Luther, NL Harris
Cell Rep, 2019-05-21;27(8):2442-2458.e5.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-F -
EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells
Authors: S Grainger, N Nguyen, J Richter, J Setayesh, B Lonquich, CH Oon, JM Wozniak, R Barahona, CN Kamei, J Houston, M Carrillo-T, IA Drummond, D Gonzalez, K Willert, D Traver
Nat. Cell Biol., 2019-05-20;21(6):721-730.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
Authors: Mercedes Segovia, Sofia Russo, Mathias Jeldres, Yamil D. Mahmoud, Valentina Perez, Maite Duhalde et al.
Cancer Cell
-
Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T�cells
Authors: M William, LP Leroux, V Chaparro, TE Graber, T Alain, M Jaramillo
Eur. J. Immunol., 2019-05-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells
Authors: Stella J. Berendam, Alexander F. Koeppel, Nicole R. Godfrey, Sherin J. Rouhani, Amber N. Woods, Anthony B. Rodriguez et al.
Frontiers in Immunology
-
Experimental non-alcoholic steatohepatitis in G�ttingen Minipigs: consequences of high fat-fructose-cholesterol diet and diabetes
Authors: C Schumacher, BØ Christoffe, RK Kirk, TP Ludvigsen, NE Zois, HD Pedersen, M Vyberg, LH Olsen
J Transl Med, 2019-04-03;17(1):110.
Species: Porcine
Sample Types: Whole Tissue
Applications: IHC -
Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility
Authors: Yunhao Tan, Jonathan C. Kagan
Cell
-
Sox7 negatively regulates prostate‐specific membrane antigen (PSMA) expression through PSMA‐enhancer
Authors: Wei Peng, Lizheng Guo, Ruoyi Tang, Xiuju Liu, Rui Jin, Jin‐Tang Dong et al.
The Prostate
-
Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion
Authors: B Li, TN Song, FR Wang, C Yin, Z Li, JP Lin, YQ Meng, HM Feng, T Jing
Oncogenesis, 2019-02-22;8(3):17.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC
Authors: B John, C Naczki, C Patel, A Ghoneum, S Qasem, Z Salih, N Said
Oncogene, 2019-02-14;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina
Authors: C Balser, A Wolf, M Herb, T Langmann
J Neuroinflammation, 2019-02-07;16(1):26.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma.
Authors: Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park et al.
Cancer Discovery
-
Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation
Authors: Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan
Sci Rep, 2019-01-31;9(1):1022.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer
Authors: WL Hwang, HY Lan, WC Cheng, SC Huang, MH Yang
J Hematol Oncol, 2019-01-25;12(1):10.
Species: Mouse
Sample Types:
-
CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance
Authors: SM Turpin-Nol, P Hammerschm, W Chen, A Jais, K Timper, M Awazawa, S Brodesser, JC Brüning
Cell Rep, 2019-01-02;26(1):1-10.e7.
Species: Mouse
Sample Types: In Vivo
-
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux
Authors: DG Thomas, AC Doran, P Fotakis, M Westerterp, P Antonson, H Jiang, XC Jiang, JÅ Gustafsson, I Tabas, AR Tall
Cell Rep, 2018-12-26;25(13):3774-3785.e4.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy
Authors: Yi-Chun Tsai, Po-Lin Kuo, Wei-Wen Hung, Ling-Yu Wu, Ping-Hsun Wu, Wei-An Chang et al.
Molecular Therapy - Nucleic Acids
-
microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11
Authors: Wei-Luo Cai, Wen-Ding Huang, Bo Li, Tian-Rui Chen, Zhen-Xi Li, Cheng-Long Zhao et al.
Molecular Cancer
-
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
Authors: T Hadi, L Boytard, M Silvestro, D Alebrahim, S Jacob, J Feinstein, K Barone, W Spiro, S Hutchison, R Simon, D Rateri, F Pinet, D Fenyo, M Adelman, KJ Moore, HK Eltzschig, A Daugherty, B Ramkhelawo
Nat Commun, 2018-11-27;9(1):5022.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation
Authors: F De Falco, B Del Papa, S Baldoni, R Sabatini, F Falzetti, M Di Ianni, MP Martelli, F Mezzasoma, M Pelullo, P Marconi, P Sportolett, I Screpanti, E Rosati
Cell Death Dis, 2018-11-26;9(12):1160.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
IL-34 promotes foam cell formation by enhancing CD36 expression through p38 MAPK pathway
Authors: Q Liu, J Fan, J Bai, L Peng, T Zhang, L Deng, G Wang, Y Zhao, J Nong, M Zhang, Y Wang
Sci Rep, 2018-11-26;8(1):17347.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
A20-binding inhibitor of NF-kappa B (ABIN) 2 negatively regulates allergic airway inflammation
Authors: Sonia Ventura, Florencia Cano, Yashaswini Kannan, Felix Breyer, Michael J. Pattison, Mark S. Wilson et al.
Journal of Experimental Medicine
-
Neutrophils drive type I interferon production and autoantibodies in patients with Wiskott-Aldrich syndrome
Authors: Karla E. Cervantes-Luevano, Nicoletta Caronni, Maria C. Castiello, Elena Fontana, Giulia M. Piperno, Asma Naseem et al.
Journal of Allergy and Clinical Immunology
-
Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism
Authors: LY Hung, D Sen, TK Oniskey, J Katzen, NA Cohen, AE Vaughan, W Nieves, A Urisman, MF Beers, MF Krummel, DR Herbert
Mucosal Immunol, 2018-10-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion
Authors: LE Hillers, JV D'Amato, T Chamberlin, G Paderta, LM Arendt
Neoplasia, 2018-10-12;20(11):1161-1174.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection
Authors: Behdad Zarnegar, Annika Westin, Syrmoula Evangelidou, Jenny Hallgren
Frontiers in Immunology
-
Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
Authors: Haobin Ye, Biniam Adane, Nabilah Khan, Erica Alexeev, Nichole Nusbacher, Mohammad Minhajuddin et al.
Cancer Cell
-
A new signaling cascade linking BMP4, BMPR1A, ?Np73 and NANOG impacts on stem-like human cell properties and patient outcome
Authors: T Voeltzel, M Flores-Vio, F Zylberszte, S Lefort, M Billandon, S Jeanpierre, S Joly, G Fossard, M Milenkov, F Mazurier, A Nehme, A Belhabri, E Paubelle, X Thomas, M Michallet, F Louache, FE Nicolini, C Caron de F, V Maguer-Sat
Cell Death Dis, 2018-09-27;9(10):1011.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Functional Assay -
Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
Authors: Ping Yang, Shan Lv, Yan Wang, Yi Peng, Zixing Ye, Zhuying Xia et al.
Bone
-
Sensitive and Specific Detection of Platelet-Derived and Tissue Factor–Positive Extracellular Vesicles in Plasma Using Solid-Phase Proximity Ligation Assay
Authors: Åsa Thulin, Junhong Yan, Mikael Åberg, Christina Christersson, Masood Kamali-Moghaddam, Agneta Siegbahn
TH Open
-
Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation
Authors: F Ferrandino, G Bernardini, G Tsaouli, P Grazioli, AF Campese, C Noce, A Ciuffetta, A Vacca, ZM Besharat, D Bellavia, I Screpanti, MP Felli
Oncogene, 2018-07-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
TCR transgenic mice reveal step-wise, multi-site acquisition of the distinctive fat-Treg phenotype
Authors: Chaoran Li, Joanna R. DiSpirito, David Zemmour, Raul German Spallanzani, Wilson Kuswanto, Christophe Benoist et al.
Cell
-
Idiopathic infertility in women is associated with distinct changes in proliferative phase uterine fluid proteins
Authors: HC Fitzgerald, J Evans, N Johnson, G Infusini, A Webb, LJR Rombauts, BJ Vollenhove, LA Salamonsen, TA Edgell
Biol. Reprod., 2018-06-01;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression
Authors: F Wang, B Li, Y Wei, Y Zhao, L Wang, P Zhang, J Yang, W He, H Chen, Z Jiao, Y Li
Oncogenesis, 2018-05-25;7(5):41.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer
Authors: Q Guo, T Grimmig, G Gonzalez, A Giobbie-Hu, G Berg, N Carr, BJ Wilson, P Banerjee, J Ma, JS Gold, B Nandi, Q Huang, AM Waaga-Gass, CG Lian, GF Murphy, MH Frank, M Gasser, NY Frank
J. Biol. Chem., 2018-05-22;0(0):.
Species: Xenograft
Sample Types: Whole Cells
Applications: Flow Cytometry -
Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1?
Authors: HM Hsiao, R Fernandez, S Tanaka, W Li, JH Spahn, S Chiu, M Akbarpour, D Ruiz-Perez, Q Wu, C Turam, D Scozzi, T Takahashi, HP Luehmann, V Puri, GRS Budinger, AS Krupnick, AV Misharin, KJ Lavine, Y Liu, AE Gelman, A Bharat, D Kreisel
J. Clin. Invest., 2018-05-21;128(7):2833-2847.
Species: Mouse
Sample Types: Whole Cells
-
Gdnf, Neurturin and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute To Inflammatory Bone Pain
Authors: S Nencini, M Ringuet, DH Kim, C Greenhill, JJ Ivanusic
J. Neurosci., 2018-04-30;0(0):.
Species: Rat
Sample Types: In Vivo
Applications: Isotype Control -
Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models
Authors: CEJ Waterborg, S Beermann, MGA Broeren, MB Bennink, MI Koenders, PLEM van Lent, WB van den Be, PM van der Kr, FAJ van de Loo
Front Immunol, 2018-04-13;9(0):742.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Human IgG Increases Virulence of Streptococcus pyogenes through Complement Evasion.
Authors: Ermert D, Weckel A, Magda M, Morgelin M, Shaughnessy J, Rice P, Bjorck L, Ram S, Blom A
J Immunol, 2018-04-06;200(10):3495-3505.
Species: Bacteria - Streptococcus pyogenes
Sample Types: Bacteria
Applications: Control -
Asparaginyl endopeptidase enhances pancreatic ductal adenocarcinoma cell invasion in an exosome-dependent manner and correlates with poor prognosis
Authors: Qiang Yan, Wen-Bin Yuan, Xu Sun, Ming-Jie Zhang, Feng Cen, Shi-Yu Zhou et al.
International Journal of Oncology
-
Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
Authors: X Qu, X Dang, W Wang, Y Li, D Xu, D Shang, Y Chang
Mediators Inflamm., 2018-03-13;2018(0):7501851.
Species: Human
Sample Types: Cell Culture Supernates, Protein
Applications: Isotype Control -
The SMAD2/3 interactome reveals that TGF? controls m6A mRNA methylation in pluripotency
Authors: A Bertero, S Brown, P Madrigal, A Osnato, D Ortmann, L Yiangou, J Kadiwala, NC Hubner, IR de Los Moz, C Sadée, AS Lenaerts, S Nakanoh, R Grandy, E Farnell, J Ule, HG Stunnenber, S Mendjan, L Vallier
Nature, 2018-02-28;555(7695):256-259.
Species: Human
Sample Types: Protein
Applications: Immunoprecipitation -
Osteopontin contributes to effective neutrophils recruitment, IL-1? production, and apoptosis in Aspergillus fumigatus keratitis
Authors: G Zhao, M Hu, C Li, J Lee, K Yuan, G Zhu, C Che
Immunol. Cell Biol., 2018-02-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Authors: JP Böttcher, E Bonavita, P Chakravart, H Blees, M Cabeza-Cab, S Sammicheli, NC Rogers, E Sahai, S Zelenay, C Reis E Sou
Cell, 2018-02-08;172(5):1022-1037.e14.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Exercise Protects Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J Mice
Authors: Laura N. Castellani, Willem T. Peppler, Paula M. Miotto, Natasha Bush, David C. Wright
Scientific Reports
-
DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients
Authors: Leen J M Seys, W Widagdo, Fien M Verhamme, Alex Kleinjan, Wim Janssens, Guy F Joos et al.
Clinical Infectious Diseases
-
Eosinophil persistence in vivo and sustained viability ex vivo in response to respiratory challenge with fungal allergens
Authors: Wendy E. Geslewitz, Caroline M. Percopo, Helene F. Rosenberg
Clinical & Experimental Allergy
-
The reduced osteogenic potential of Nf1-deficient osteoprogenitors is EGFR-independent
Authors: S.E. Tahaei, G. Couasnay, Y. Ma, N. Paria, J. Gu, B. F. Lemoine et al.
Bone
-
Interleukin-22 participates in the inflammatory process of vitiligo
Authors: Jinjin Dong, Xiaohong An, Hui Zhong, Yichuan Wang, Jing Shang, Jia Zhou
Oncotarget
-
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
Authors: I Gregersen, Ø Sandanger, ET Askevold, EL Sagen, K Yang, S Holm, TM Pedersen, M Skjelland, K Krohg-Søre, TV Hansen, TB Dahl, K Otterdal, T Espevik, P Aukrust, A Yndestad, B Halvorsen
PLoS ONE, 2017-11-27;12(11):e0188387.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372
Authors: Claudio Coddou, Rodrigo Sandoval, Patricio Castro, Pablo Lazcano, Maria José Hevia, Milos Rokic et al.
Pain
-
IFN-?4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling
Authors: AA Obajemu, N Rao, KA Dilley, JM Vargas, F Sheikh, RP Donnelly, RS Shabman, EG Meissner, L Prokunina-, OO Onabajo
J. Immunol., 2017-10-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Chronic hepatitis C liver microenvironment: role of the Th17/Treg interplay related to fibrogenesis
Authors: DA Rios, P Valva, PC Casciato, S Frias, M Soledad Ca, MI Gaillard, L Bezrodnik, J Bandi, O Galdame, B Ameigeiras, D Krasniansk, C Brodersen, E Mullen, EN Matteo, MV Preciado
Sci Rep, 2017-10-16;7(1):13283.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation
Authors: SN Cross, JA Potter, P Aldo, JY Kwon, M Pitruzzell, M Tong, S Guller, CV Rothlin, G Mor, VM Abrahams
J. Immunol., 2017-09-15;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Neutralization -
Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma
Authors: Blake A. Jacobson, Ahad A. Sadiq, Shaogeng Tang, Joe Jay-Dixon, Manish R. Patel, Jeremy Drees et al.
Oncotarget
-
Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
JCI Insight, 2017-09-07;2(17):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
JCI Insight, 2017-09-07;2(17):.
Species: Mouse
Sample Types: Complex Sample Type
Applications: Isotype Control -
IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury
Authors: M Geha, MG Tsokos, RE Bosse, T Sannikova, Y Iwakura, JJ Dalle Lucc, R De Waal Ma, GC Tsokos
J. Immunol., 2017-09-06;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells
Authors: Y Shlyakhtin, V Pavet, H Gronemeyer
Cell Death Dis, 2017-08-31;8(8):e3025.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Gpr158 mediates osteocalcin's regulation of cognition
Authors: L Khrimian, A Obri, M Ramos-Bros, A Rousseaud, S Moriceau, AS Nicot, P Mera, S Kosmidis, T Karnavas, F Saudou, XB Gao, F Oury, E Kandel, G Karsenty
J. Exp. Med., 2017-08-29;214(10):2859-2873.
Species: Mouse
Sample Types: Beads
Applications: Binding Control -
Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms
Authors: Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst et al.
Nature Communications
-
Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea
Authors: P Mirabelli, A Mukwaya, A Lennikov, M Xeroudaki, B Peebo, M Schaupper, N Lagali
Sci Rep, 2017-08-15;7(1):7616.
Species: Rat
Sample Types: In Vivo
Applications: Neutralization -
IL-33 Signaling Regulates Innate IL-17A and IL-22 Production via Suppression of Prostaglandin E2 during Lung Fungal Infection
Authors: JM Garth, KM Reeder, MS Godwin, JJ Mackel, CW Dunaway, JP Blackburn, C Steele
J. Immunol., 2017-08-07;199(6):2140-2148.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
Stem Cell Reports, 2017-08-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus
Authors: Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson
PLoS Pathog., 2017-07-31;13(7):e1006536.
Species: Mouse
Sample Types: In Vivo
-
Integrin ?3/Akt signaling contributes to platelet-induced hemangioendothelioma growth
Authors: R Gu, X Sun, Y Chi, Q Zhou, H Xiang, DB Bosco, X Lai, C Qin, KF So, Y Ren, XM Chen
Sci Rep, 2017-07-25;7(1):6455.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness
Authors: M Bugge, B Bergstrom, OK Eide, H Solli, IF Kjønstad, J Stenvik, T Espevik, NJ Nilsen
J. Biol. Chem., 2017-07-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity
Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo
Nat Commun, 2017-07-07;8(0):16003.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression
Authors: M Rokavec, M Kaller, D Horst, H Hermeking
Sci Rep, 2017-07-05;7(1):4687.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease
Authors: Stefan Uderhardt, Jochen A. Ackermann, Tobias Fillep, Victoria J. Hammond, Johann Willeit, Peter Santer et al.
Journal of Experimental Medicine
-
Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis
Authors: AP Vicari, AM Schoepfer, B Meresse, L Goffin, O Léger, S Josserand, N Guégan, S Yousefi, A Straumann, N Cerf-Bensu, HU Simon, Y Chvatchko
MAbs, 2017-06-05;0(0):0.
-
SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer
Authors: Lúcia L. Correia, Jo-Anne Johnson, Peter McErlean, Julien Bauer, Hassan Farah, Doris M. Rassl et al.
American Journal of Respiratory and Critical Care Medicine
-
A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells
Authors: MM Varnum, KA Clayton, A Yoshii-Kit, G Yonemoto, L Koro, S Ikezu, T Ikezu
J. Biol. Chem., 2017-05-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Functional Assay -
IL‐10‐producing, ST2‐expressing Foxp3 + T cells in multiple sclerosis brain lesions
Authors: Stephanie Elizabeth Johanna Zandee, Richard Anthony O'Connor, Iris Mair, Melanie Dawn Leech, Anna Williams, Stephen Mark Anderton
Immunology & Cell Biology
-
Hypoxia-induced HIF1 alpha targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis
Authors: Stacie K. Loftus, Laura L. Baxter, Julia C. Cronin, Temesgen D. Fufa, William J. NISC Comparative Sequencing Program, William J. NISC Comparative Sequencing Program
Pigment Cell & Melanoma Research
-
Gene expression profiling in bladder cancer identifies potential therapeutic targets
Authors: Syed A. Hussain, Daniel H. Palmer, Wing-Kin Syn, Joseph J. Sacco, Richard M.D. Greensmith, Taha Elmetwali et al.
International Journal of Oncology
-
Netrin 1 mediates protective effects exerted by insulin-like growth factor 1 on cochlear hair cells
Authors: K Yamahara, T Nakagawa, J Ito, K Kinoshita, K Omori, N Yamamoto
Neuropharmacology, 2017-04-01;119(0):26-39.
Species: Mouse
Sample Types: Whole Cells
Applications: Functional Assay, Neutralization -
Tumor necrosis factor alpha derived from classically activated “M1” macrophages reduces interstitial cell of Cajal numbers
Authors: Seth T. Eisenman, Simon J. Gibbons, Pieter-Jan Verhulst, Gianluca Cipriani, Dieter Saur, Gianrico Farrugia
Neurogastroenterology & Motility
-
Human Immunodeficiency Virus Type-1 Myeloid Derived Suppressor Cells Inhibit Cytomegalovirus Inflammation through Interleukin-27 and B7-H4
Authors: A Garg, R Trout, SA Spector
Sci Rep, 2017-03-24;7(0):44485.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes
Authors: JF Bogie, J Mailleux, E Wouters, W Jorissen, E Grajchen, J Vanmol, K Wouters, N Hellings, J Van Horsen, T Vanmierlo, JJ Hendriks
Sci Rep, 2017-03-20;7(0):44794.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A
Authors: R Velázquez-, M Law, J Bukh, J Prentoe
PLoS Pathog, 2017-02-23;13(2):e1006214.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele
Authors: Su Hwa Jang, Helen Chen, Peter K. Gregersen, Betty Diamond, Sun Jung Kim
JCI Insight
-
Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation
Authors: S Esnault, EE Torr, K Bernau, MW Johansson, EA Kelly, N Sandbo, NN Jarjour
PLoS ONE, 2017-01-17;12(1):e0170207.
Species: Human
Sample Types: Whole Cells
Applications: ICC Control -
Combined Effects of Androgen and Growth Hormone on Osteoblast Marker Expression in Mouse C2C12 and MC3T3-E1 Cells Induced by Bone Morphogenetic Protein
Authors: K Kimura, T Terasaka, N Iwata, T Katsuyama, M Komatsubar, R Nagao, K Inagaki, F Otsuka
J Clin Med, 2017-01-05;6(1):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
Autophagy, 2017-01-01;0(0):0.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Sclerostin does not play a major role in the pathogenesis of skeletal complications in type 2 diabetes mellitus
Authors: M. Pereira, S. Gohin, N. Lund, A. Hvid, P. J. Smitham, M. J. Oddy et al.
Osteoporosis International
-
Osteopontin Blockade Attenuates Renal Injury After Ischemia Reperfusion by Inhibiting NK Cell Infiltration
Authors: Cindy Cen, Monowar Aziz, Weng-Lang Yang, Jeffrey M. Nicastro, Gene F. Coppa, Ping Wang
Shock
-
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Authors: Hoeke A Baarsma
J. Exp. Med, 2016-12-15;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms
Nat. Med, 2016-12-05;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Zika virus cell tropism in the developing human brain and inhibition by azithromycin
Proc. Natl. Acad. Sci. U.S.A., 2016-11-29;113(50):14408-14413.
Species: Human, Primate
Sample Types: Whole Cells
Applications: Neutralization -
Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver
Authors: Leslie E Rogler
J. Histochem. Cytochem., 2016-11-24;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: ICC -
PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently
Authors: L Zheng, C Zhao, Y Du, X Lin, Y Jiang, C Lee, G Tian, J Mi, X Li, Q Chen, Z Ye, L Huang, S Wang, X Ren, L Xing, W Chen, D Huang, Z Gao, S Zhang, W Lu, Z Tang, B Wang, R Ju, X Li
Oncotarget, 2016-11-22;7(47):77902-77915.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy
Sci Rep, 2016-11-17;6(0):37209.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Novel anti-EPHA2 antibody, DS-8895a for cancer treatment
Authors: Jun Hasegawa, Mayumi Sue, Michiko Yamato, Junya Ichikawa, Saori Ishida, Tomoko Shibutani et al.
Cancer Biology & Therapy
-
A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo.
Authors: Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, Feldman B
Sci Signal, 2016-10-25;9(451):ra103.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay -
Neutralization of Osteopontin Ameliorates Acute Lung Injury Induced by Intestinal Ischemia-Reperfusion
Authors: Yohei Hirano, Monowar Aziz, Weng-Lang Yang, Mahendar Ochani, Ping Wang
Shock
-
Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner
Authors: Nana Owusu-Boai
Immun Inflamm Dis, 2016-08-28;4(4):413-426.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
Mol Ther Methods Clin Dev, 2016-08-24;3(0):16056.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function
PLoS ONE, 2016-08-16;11(8):e0161235.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Antihypoxic Potentiation of Standard Therapy for Experimental Colorectal Liver Metastasis through Myo-Inositol Trispyrophosphate
Clin Cancer Res, 2016-08-03;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia
Authors: Justin S. Ko, Kelly A. Eddinger, Mila Angert, Andrei V. Chernov, Jennifer Dolkas, Alex Y. Strongin et al.
Brain, Behavior, and Immunity
-
Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways
Authors: E. Rebecca Longbottom, Hew D. T. Torrance, Helen C. Owen, Paraskevi C. Fragkou, Charles J. Hinds, Rupert M. Pearse et al.
Annals of Surgery
-
CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells
Authors: Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft et al.
Blood
-
HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1?
Mol Cell Biol, 2016-07-14;0(0):.
Species: Human
Sample Types: Chromatin
Applications: ChIP -
STAT3/5-Dependent IL9 Overexpression Contributes to Neoplastic Cell Survival in Mycosis Fungoides
Authors: Pablo A. Vieyra-Garcia, Tianling Wei, David Gram Naym, Simon Fredholm, Regina Fink-Puches, Lorenzo Cerroni et al.
Clinical Cancer Research
-
Interleukin-33 in human gliomas: Expression and prognostic significance
Authors: DOROTHEE GRAMATZKI, KARL FREI, GIERI CATHOMAS, HOLGER MOCH, MICHAEL WELLER, KIRSTEN DIANA MERTZ
Oncology Letters
-
Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33
Authors: Sara Khaleghparast Athari
Arthritis Res Ther, 2016-06-18;18(1):143.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model
Authors: Hiroki Tashiro
PLoS ONE, 2016-06-16;11(6):e0157571.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Expression and function of IL-1R8 (TIR8/SIGIRR), a regulatory member of the IL-1 receptor family in platelets
Authors: Achille Anselmo
Cardiovasc Res, 2016-06-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Ficolins Promote Fungal Clearance in vivo and Modulate the Inflammatory Cytokine Response in Host Defense against Aspergillus fumigatus
Authors: Ninette Genster, Elisabeth Præstekjær Cramer, Anne Rosbjerg, Katrine Pilely, Jack Bernard Cowland, Peter Garred
Journal of Innate Immunity
-
Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1
Authors: L Zanotti, R Angioni, B Calì, C Soldani, C Ploia, F Moalli et al.
Leukemia
-
IFN-gamma induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense
Authors: Shanshan Cai, Sanjay Batra, Ingeborg Langohr, Yochiro Iwakura, Samithamby Jeyaseelan
Mucosal Immunology
-
Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity
Authors: Shimin Wang, Xiang Gao, Guobo Shen, Wei Wang, Jingyu Li, Jingyi Zhao et al.
Scientific Reports
-
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation
Authors: C Cerri, S Genovesi, M Allegra, F Pistillo, U Püntener, A Guglielmot, VH Perry, Y Bozzi, M Caleo
J Neurosci, 2016-03-30;36(13):3777-88.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome
Authors: Lauren W. Wood, Nicole I. Cox, Cody A. Phelps, Shao-Chiang Lai, Arjun Poddar, Conover Talbot et al.
Scientific Reports
-
p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells
Authors: A J Browne, A Göbel, S Thiele, L C Hofbauer, M Rauner, T D Rachner
Cell Death & Disease
-
Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family
Authors: Sabine Stindt, Patricia Cebula, Ute Albrecht, Verena Keitel, Jan Schulte am Esch, Wolfram T. Knoefel et al.
PLOS ONE
-
Convergence of cMyc and beta-catenin on Tcf7l1 enables endoderm specification.
Authors: Morrison G, Scognamiglio R, Trumpp A, Smith A
EMBO J, 2015-12-16;35(3):356-68.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2(Akita) diabetic mouse
Authors: Jose R. Hombrebueno, Imran HA. Ali, Heping Xu, Mei Chen
Scientific Reports
-
DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements
Authors: Matthew S Wilken, Joseph A Brzezinski, Anna La Torre, Kyle Siebenthall, Robert Thurman, Peter Sabo et al.
Epigenetics & Chromatin
-
Neutralization of osteopontin attenuates neutrophil migration in sepsis-induced acute lung injury
Authors: Yohei Hirano, Monowar Aziz, Weng-Lang Yang, Zhimin Wang, Mian Zhou, Mahendar Ochani et al.
Critical Care
-
Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells
Authors: Amanda L. Hernandez, Alexandra Kitz, Chuan Wu, Daniel E. Lowther, Donald M. Rodriguez, Nalini Vudattu et al.
Journal of Clinical Investigation
-
Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets
Authors: Desirée Edén, Agneta Siegbahn, Dariush Mokhtari
Diabetologia
-
Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.
Authors: Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, Buchheit K, Bhattacharya N, Laidlaw T, Katz H, Boyce J
J Immunol, 2015-09-04;195(8):3537-45.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model
Authors: Meher Majety, Leon P. Pradel, Manuela Gies, Carola H. Ries
PLOS ONE
-
A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain
Authors: Deepitha Selvaraj, Vijayan Gangadharan, Christoph W. Michalski, Martina Kurejova, Sebastian Stösser, Kshitij Srivastava et al.
Cancer Cell
-
P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.
Authors: Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, Lu N, Wang C, Ahmed M, Lu Y, Liu Z, Shi W, Lai E, Wilcox C, Han F
Cell Res, 2015-05-22;25(6):674-90.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death
Authors: K Kataoka, H Matsumoto, H Kaneko, S Notomi, K Takeuchi, J H Sweigard et al.
Cell Death & Disease
-
The Tissue Fibrinolytic System Contributes to the Induction of Macrophage Function and CCL3 during Bone Repair in Mice.
Authors: Kawao N, Tamura Y, Horiuchi Y, Okumoto K, Yano M, Okada K, Matsuo O, Kaji H
PLoS ONE, 2015-04-20;10(4):e0123982.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
Authors: Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G
Br J Cancer, 2015-04-16;112(10):1675-86.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Discovery of molecular markers to discriminate corneal endothelial cells in the human body.
Authors: Yoshihara M, Ohmiya H, Hara S, Kawasaki S, Hayashizaki Y, Itoh M, Kawaji H, Tsujikawa M, Nishida K
PLoS ONE, 2015-03-25;10(3):e0117581.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients.
Authors: Martinez L, Labovsky V, Calcagno M, Davies K, Garcia Rivello H, Bianchi M, Wernicke A, Fernandez Vallone V, Chasseing N
PLoS ONE, 2015-03-24;10(3):e0121421.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71.
Authors: Leong, Shi Yun, Ong, Bryan Ki, Chu, Justin J
PLoS Pathog, 2015-03-06;11(3):e1004686.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers.
Authors: Walker W, Kurscheid S, Joshi S, Lopez C, Goh G, Choi M, Barakat L, Francis J, Fisher A, Kozal M, Zapata H, Shaw A, Lifton R, Sutton R, Fikrig E
J Virol, 2015-03-04;89(10):5502-14.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitis.
Authors: Araujo-Pires A, Vieira A, Francisconi C, Biguetti C, Glowacki A, Yoshizawa S, Campanelli A, Trombone A, Sfeir C, Little S, Garlet G
J Bone Miner Res, 2015-03-01;30(3):412-22.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
Authors: Chien C, Lee M, Liou H, Liou H, Fu W
PLoS ONE, 2015-02-23;10(2):e0115827.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium.
Authors: Xu J, Singhera G, Dorscheid D
Respir Res, 2015-02-15;16(0):26.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.
Authors: Ortiz M, Kumar V, Martner A, Mony S, Donthireddy L, Condamine T, Seykora J, Knight S, Malietzis G, Lee G, Moorghen M, Lenox B, Luetteke N, Celis E, Gabrilovich D
J Exp Med, 2015-02-09;212(3):351-67.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Spinal NF-kappaB and chemokine ligand 5 expression during spinal glial cell activation in a neuropathic pain model.
Authors: Yin Q, Fan Q, Zhao Y, Cheng M, Liu H, Li J, Lu F, Jia J, Cheng W, Yan C
PLoS ONE, 2015-01-30;10(1):e0115120.
Species: Rat
Sample Types: In Vivo
Applications: Neutralization, Neutralization Control -
IL-1alpha signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge.
Authors: Caffrey A, Lehmann M, Zickovich J, Espinosa V, Shepardson K, Watschke C, Hilmer K, Thammahong A, Barker B, Rivera A, Cramer R, Obar J
PLoS Pathog, 2015-01-28;11(1):e1004625.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M
J Virol, 2015-01-21;89(7):3859-69.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Crucial role of IL1beta and C3a in the in vitro-response of multipotent mesenchymal stromal cells to inflammatory mediators of polytrauma.
Authors: Hengartner N, Fiedler J, Schrezenmeier H, Huber-Lang M, Brenner R
PLoS ONE, 2015-01-06;10(1):e0116772.
Species: Human
Sample Types: Whole Cells
Applications: Blocking -
Treatment with Anti-EGF Ab Ameliorates Experimental Autoimmune Encephalomyelitis via Induction of Neurogenesis and Oligodendrogenesis
Authors: Yifat Amir-Levy, Karin Mausner-Fainberg, Arnon Karni
Multiple Sclerosis International
-
Lymphotoxin beta receptor signaling induces IL-8 production in human bronchial epithelial cells.
Authors: Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y
PLoS ONE, 2014-12-11;9(12):e114791.
Species: Human
Sample Types: Cell Lysates
Applications: Isotype Control -
Fatty Acid Binding Protein 7 Is a Molecular Marker in Adenoid Cystic Carcinoma of the Salivary Glands: Implications for Clinical Significance12
Authors: Janyaporn Phuchareon, Jonathan B. Overdevest, Frank McCormick, David W. Eisele, Annemieke van Zante, Osamu Tetsu
Translational Oncology
-
The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
Authors: Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister H, Alexander T, Hiepe F, Kumpfel T, Crawford H, Wekerle H, Hohlfeld R, Lichtenthaler S, Meinl E
J Immunol, 2014-12-10;194(2):542-52.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Immunoprecipitation -
Monocyte chemoattractant protein 1 (MCP-1/CCL2) contributes to thymus atrophy in acute myeloid leukemia.
Authors: Driss V, Quesnel B, Brinster C
Eur J Immunol, 2014-12-04;45(2):396-406.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells.
Authors: Crosley, Erin J, Dunk, Caroline, Beristain, Alexande, Christians, Julian K
Reprod Biol Endocrinol, 2014-12-04;12(0):123.
Species: Human
Sample Types: Whole Tissue
Applications: IHC Control -
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes
Authors: Menna R. Clatworthy, Caren E. Petrie Aronin, Rebeccah J. Mathews, Nicole Y Morgan, Kenneth G.C. Smith, Ronald N. Germain
Nature Medicine
-
An anti-inflammatory property of Candida albicans beta-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Authors: Smeekens S, Gresnigt M, Becker K, Cheng S, Netea S, Jacobs L, Jansen T, van de Veerdonk F, Williams D, Joosten L, Dinarello C, Netea M
Cytokine, 2014-11-20;71(2):215-22.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Stromal TGF-beta signaling induces AR activation in prostate cancer
Authors: Feng Yang, Yizhen Chen, Tao Shen, Dan Guo, Olga Dakhova, Michael M. Ittmann et al.
Oncotarget
-
Cytokine signaling by grafted neuroectodermal stem cells rescues motoneurons destined to die
Authors: Krisztián Pajer, Georg A. Feichtinger, Gábor Márton, Sonja Sabitzer, Dieter Klein, Heinz Redl et al.
Experimental Neurology
-
HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation
Authors: Y Huang, J Chen, C Lu, J Han, G Wang, C Song et al.
Cell Death & Disease
-
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
Nature, 2014-10-22;515(7525):130-3.
Species: Mouse
Sample Types: In Vivo
-
Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production.
Authors: Gringhuis S, Kaptein T, Wevers B, van der Vlist M, Klaver E, van Die I, Vriend L, de Jong M, Geijtenbeek T
Nat Commun, 2014-10-03;5(0):5074.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling.
Authors: Hwang D, Shin H, Kwon M, Choi J, Ryu B, Kim B
J Neurosci, 2014-09-17;34(38):12788-800.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Diversification of TAM receptor tyrosine kinase function.
Authors: Zagorska A, Traves P, Lew E, Dransfield I, Lemke G
Nat Immunol, 2014-09-07;15(10):920-8.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7.
Authors: Su, Boxing, Zhao, Wei, Shi, Bentao, Zhang, Zhongyua, Yu, Xi, Xie, Feng, Guo, Zhongqia, Zhang, Xiaoyu, Liu, Jin, Shen, Qi, Wang, Jinghua, Li, Xuesong, Zhang, Zhiqian, Zhou, Liqun
Mol Cancer, 2014-09-06;13(0):206.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Measles Vaccine Strains for Virotherapy of Non–Small-Cell Lung Carcinoma
Authors: Manish R. Patel, Blake A. Jacobson, Holly Belgum, Ahmad Raza, Ahad Sadiq, Jeremy Drees et al.
Journal of Thoracic Oncology
-
Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients.
Authors: Haga E, Endo Y, Haruta M, Koba C, Matsumura K, Takamatsu K, Ikeda T, Nishimura Y, Senju S
J Immunol, 2014-07-16;193(4):2024-33.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia.
Authors: Le D, Rochlitzer S, Fischer A, Heck S, Tschernig T, Sester M, Bals R, Welte T, Braun A, Dinh Q
Respir Res, 2014-06-30;15(0):73.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Brain glycolipids suppress T helper cells and inhibit autoimmune demyelination.
Authors: Mycko M, Sliwinska B, Cichalewska M, Cwiklinska H, Raine C, Selmaj K
J Neurosci, 2014-06-18;34(25):8646-58.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
Am J Physiol Endocrinol Metab, 2014-06-03;307(2):E186-98.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1–6
Authors: Christian K. Mathiesen, Tanja B. Jensen, Jannick Prentoe, Henrik Krarup, Alfredo Nicosia, Mansun Law et al.
Virology
-
Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils.
Authors: Wen T, Mingler M, Wahl B, Khorki M, Pabst O, Zimmermann N, Rothenberg M
J Immunol, 2014-05-07;192(12):5481-9.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability.
Authors: Hendel, Alon, Hsu, Ivy, Granville, David J
Lab Invest, 2014-05-05;94(7):716-25.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects
Authors: Stelios Vittorakis, Konstantinos Samitas, Sofia Tousa, Eleftherios Zervas, Maria Aggelakopoulou, Maria Semitekolou et al.
BioMed Research International
-
Gene Expression Pattern of Cells From Inflamed and Normal Areas of Osteoarthritis Synovial Membrane
Authors: Cécile Lambert, Jean‐Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël et al.
Arthritis & Rheumatology
-
The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck.
Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M
PLoS Pathog, 2014-03-20;10(3):e1004026.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth.
Authors: Mogami, Haruta, Keller, Patrick, Shi, Haolin, Word, R Ann
J Biol Chem, 2014-03-20;289(19):13295-307.
Species: Human
Sample Types: Cell Lysates
Applications: Neutralization Control -
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
Nat Med, 2014-03-02;20(4):377-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Attenuation of intestinal inflammation in interleukin-10-deficient mice infected with Citrobacter rodentium.
Authors: Dann, Sara M, Le, Christin, Choudhury, Barun K, Liu, Houpu, Saldarriaga, Omar, Hanson, Elaine M, Cong, Yingzi, Eckmann, Lars
Infect Immun, 2014-02-24;82(5):1949-58.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Authors: Paolino, Magdalen, Choidas, Axel, Wallner, Stephani, Pranjic, Blanka, Uribesalgo, Iris, Loeser, Stefanie, Jamieson, Amanda M, Langdon, Wallace, Ikeda, Fumiyo, Fededa, Juan Pab, Cronin, Shane J, Nitsch, Roberto, Schultz-Fademrecht, Carsten, Eickhoff, Jan, Menninger, Sascha, Unger, Anke, Torka, Robert, Gruber, Thomas, Hinterleitner, Reinhard, Baier, Gottfrie, Wolf, Dominik, Ullrich, Axel, Klebl, Bert M, Penninger, Josef M
Nature, 2014-02-19;507(7493):508-12.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone.
Authors: Shigemoto-Mogami Y, Hoshikawa K, Goldman J, Sekino Y, Sato K
J Neurosci, 2014-02-05;34(6):2231-43.
Species: Rat
Sample Types: Whole Cells
Applications: Neutralization -
Quantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity.
Authors: Wang H, Yang Z, Jiang Y, Flannery J, Hammond S, Kafri T, Vemuri S, Jones B, Hartnett M
Invest Ophthalmol Vis Sci, 2014-02-04;55(2):737-44.
Species: Rat
Sample Types: In Vivo
Applications: Control -
Hypervariable Region 1 Deletion and Required Adaptive Envelope Mutations Confer Decreased Dependency on Scavenger Receptor Class B Type I and Low-Density Lipoprotein Receptor for Hepatitis C Virus
Authors: Jannick Prentoe, Stéphanie B. N. Serre, Santseharay Ramirez, Alfredo Nicosia, Judith M. Gottwein, Jens Bukh
Journal of Virology
-
IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis.
Authors: Liu J, Harberts E, Tammaro A, Girardi N, Filler R, Fishelevich R, Temann A, Licona-Limon P, Girardi M, Flavell R, Gaspari A
J Invest Dermatol, 2014-01-31;134(7):1903-11.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Authors: Bulau A, Nold M, Li S, Nold-Petry C, Fink M, Mansell A, Schwerd T, Hong J, Rubartelli A, Dinarello C, Bufler P
Proc Natl Acad Sci U S A, 2014-01-30;111(7):2650-5.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage.
Authors: Menkhorst E, Gamage T, Cuman C, Kaitu'u-Lino T, Tong S, Dimitriadis E
Placenta, 2014-01-24;35(3):195-201.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Cytoplasmic protein methylation is essential for neural crest migration.
Authors: Vermillion K, Lidberg K, Gammill L
J Cell Biol, 2013-12-30;204(1):95-109.
Species: Chicken
Sample Types: Cell Lysates
Applications: Neutralization -
The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1.
Authors: Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman B, Fauci A, Lusso P
PLoS Pathog, 2013-12-26;9(12):e1003852.
Species: Human
Sample Types: Recombinant Protein
Applications: Co-Immunoprecipitation -
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival
Authors: Michail S. Lionakis, Muthulekha Swamydas, Brett G. Fischer, Theo S. Plantinga, Melissa D. Johnson, Martin Jaeger et al.
Journal of Clinical Investigation
-
Protein Kinase Inhibitor gamma Reciprocally Regulates Osteoblast and Adipocyte Differentiation by Downregulating Leukemia Inhibitory Factor
Authors: Xin Chen, Bryan S. Hausman, Guangbin Luo, Guang Zhou, Shunichi Murakami, Janet Rubin et al.
Stem Cells
-
High-Content Analysis to Leverage a Robust Phenotypic Profiling Approach to Vascular Modulation
Authors: Beverley J. Isherwood, Rebecca E. Walls, Mark E. Roberts, Thomas M. Houslay, Sandra R. Brave, Simon T. Barry et al.
J Biomol Screen
-
IL-11 produced by breast cancer cells augments osteoclastogenesis by sustaining the pool of osteoclast progenitor cells
Authors: Erin M McCoy, Huixian Hong, Hawley C Pruitt, Xu Feng
BMC Cancer
-
Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes.
Authors: Boku, Shuken, Hisaoka-Nakashima, Kazue, Nakagawa, Shin, Kato, Akiko, Kajitani, Naoto, Inoue, Takeshi, Kusumi, Ichiro, Takebayashi, Minoru
PLoS ONE, 2013-11-18;8(11):e79371.
Species: Rat
Sample Types: Whole Cells
Applications: Neutralization Control -
NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S
PLoS ONE, 2013-11-11;8(11):e78728.
Applications: Isotype Control -
Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.
Authors: Lee, Cleo Yi-, Lin, Yuan, Bratman, Scott V, Feng, Weiguo, Kuo, Angera H, Scheeren, Ferenc A, Engreitz, Jesse M, Varma, Sushama, West, Robert B, Diehn, Maximili
Cancer Res, 2013-10-31;74(1):341-52.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.
Authors: Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, Ruan J, Xia L
Cancer Res, 2013-10-24;73(24):7254-64.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization Control -
IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice.
Authors: Visperas A, Do J, Bulek K, Li X, Min B
Mucosal Immunol, 2013-10-16;7(3):625-33.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence.
Authors: Brzezinski J, Uoon Park K, Reh T
Dev Biol, 2013-10-12;384(2):194-204.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Immunoprecipitation -
ROR1 Flow Cytometry
Authors: Vincent T Bicocca, Jeffrey W Tyner
BIO-PROTOCOL
-
Immunoprecipitation of ROR1
Authors: Vincent T Bicocca, Jeffrey W Tyner
BIO-PROTOCOL
-
A distant, cis-acting enhancer drives induction of Arf by Tgf beta in the developing eye
Authors: Yanbin Zheng, Caitlin Devitt, Jing Liu, Jie Mei, Stephen X. Skapek
Developmental Biology
-
T cell-derived microvesicles induce mast cell production of IL-24: relevance to inflammatory skin diseases.
Authors: Shefler I, Pasmanik-Chor M, Kidron D, Mekori Y, Hershko A
J Allergy Clin Immunol, 2013-06-12;133(1):217-24.e1-3.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Lack of oncostatin M receptor beta leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype.
Authors: Komori T, Tanaka M, Senba E, Miyajima A, Morikawa Y
J Biol Chem, 2013-06-11;288(30):21861-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
OX40L/Jagged1 Cosignaling by GM-CSF–Induced Bone Marrow-Derived Dendritic Cells Is Required for the Expansion of Functional Regulatory T Cells
Authors: Anupama Gopisetty, Palash Bhattacharya, Christine Haddad, Joseph C. Bruno, Chenthamarakshan Vasu, Lucio Miele et al.
The Journal of Immunology
-
Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice.
Authors: Mizutani N, Nabe T, Yoshino S
Immunology, 2013-06-01;139(2):205-18.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
A role for PVRL4-driven cell-cell interactions in tumorigenesis.
Authors: Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, Elledge S
Elife, 2013-04-30;2(0):e00358.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-22 exacerbates the severity of CVB3-induced acute viral myocarditis in IL-17A-deficient mice
Authors: QING KONG, YIMIN XUE, WEIFENG WU, FAN YANG, YANLI LIU, MENGSHA GAO et al.
Molecular Medicine Reports
-
Interaction between CX3CL1 and CX3CR1 regulates vasculitis induced by immune complex deposition.
Authors: Morimura S, Sugaya M, Sato S
Am J Pathol, 2013-03-05;182(5):1640-7.
Species: Mouse
Sample Types: Whole Tissue
-
Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma.
Authors: Kan-o K, Matsunaga Y, Fukuyama S, Moriwaki A, Hirai-Kitajima H, Yokomizo T, Aritake K, Urade Y, Nakanishi Y, Inoue H, Matsumoto K
Respir Res, 2013-03-04;14(0):28.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Spatiotemporal Expression of Repulsive Guidance Molecules (RGMs) and Their Receptor Neogenin in the Mouse Brain
Authors: Dianne M. A. van den Heuvel, Anita J. C. G. M. Hellemons, R. Jeroen Pasterkamp
PLoS ONE
-
Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells.
Authors: Loebbermann, Jens, Durant, Lydia, Thornton, Hannah, Johansson, Cecilia, Openshaw, Peter J
Proc Natl Acad Sci U S A, 2013-02-04;110(8):2987-92.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.
Authors: Yang, Guang, Holl, T Matt, Liu, Yang, Li, Yi, Lu, Xiaozhi, Nicely, Nathan I, Kepler, Thomas B, Alam, S Munir, Liao, Hua-Xin, Cain, Derek W, Spicer, Leonard, VandeBerg, John L, Haynes, Barton F, Kelsoe, Garnett
J Exp Med, 2013-01-28;210(2):241-56.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression.
Authors: Iida, Yasunori, Xu, Baohui, Xuan, Haojun, Glover, Keith J, Tanaka, Hiroki, Hu, Xiaolei, Fujimura, Naoki, Wang, Wei, Schultz, Joshua R, Turner, Court R, Dalman, Ronald L
Arterioscler Thromb Vasc Biol, 2013-01-03;33(4):718-26.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Increased Expressions of IL-22 and Th22 cells in the coxsackievirus B3-Induced mice acute viral myocarditis
Authors: Qing Kong, Weifeng Wu, Fan Yang, Yanli Liu, Yimin Xue, Mengsha Gao et al.
Virology Journal
-
Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
J Biol Chem, 2012-11-26;288(3):1953-66.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Transforming growth factor Beta 3 is required for excisional wound repair in vivo.
Authors: Le M, Naridze R, Morrison J, Biggs L, Rhea L, Schutte B, Kaartinen V, Dunnwald M
PLoS ONE, 2012-10-26;7(10):e48040.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.
Authors: Langer, Marybeth, Duggan, Elizabet, Booth, John Lel, Patel, Vineet I, Zander, Ryan A, Silasi-Mansat, Robert, Ramani, Vijay, Veres, Tibor Zo, Prenzler, Frauke, Sewald, Katherin, Williams, Daniel M, Coggeshall, Kenneth, Awasthi, Shanjana, Lupu, Florea, Burian, Dennis, Ballard, Jimmy Da, Braun, Armin, Metcalf, Jordan P
Infect Immun, 2012-10-01;80(12):4374-87.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model.
Authors: Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L
Am J Pathol, 2012-09-07;181(5):1540-59.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling.
Authors: Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, Gonzalez A, Panjwani N
PLoS ONE, 2012-09-04;7(9):e44400.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
CCR6 is required for epidermal trafficking of gammadelta-T cells in an IL-23-induced model of psoriasiform dermatitis.
Authors: Mabuchi T, Singh T, Takekoshi T, Jia G, Wu X, Kao M, Weiss I, Farber J, Hwang S
J Invest Dermatol, 2012-08-16;133(1):164-71.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cells
Authors: Hyun-Jung Park, Ji-Yeon Baen, Ye-Ji Lee, Youn-Hee Choi, Jihee Lee Kang
Molecular Biology of the Cell
-
Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis.
J. Clin. Invest., 2012-08-06;122(9):3184-96.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE
Authors: Dirk Jochmans, Pieter Leyssen, Johan Neyts
Journal of Virological Methods
-
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.
Nat. Med., 2012-07-22;18(0):1217.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
Rodent Models of HAND and Drug Abuse: Exogenous Administration of Viral Protein(s) and Cocaine
Authors: Honghong Yao, Shilpa Buch
Journal of Neuroimmune Pharmacology
-
Leukemia inhibitory factor signaling is required for lung protection during pneumonia.
Authors: Quinton LJ, Mizgerd JP, Hilliard KL
J. Immunol., 2012-05-11;188(12):6300-8.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation.
Authors: Crawford J, Pilling D, Gomer R
J Leukoc Biol, 2012-04-09;92(4):699-711.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc.
Authors: Sakai, Daisuke, Nakamura, Yoshihik, Nakai, Tomoko, Mishima, Taishi, Kato, Shunichi, Grad, Sibylle, Alini, Mauro, Risbud, Makarand, Chan, Danny, Cheah, Kathryn, Yamamura, Ken-ichi, Masuda, Koichi, Okano, Hideyuki, Ando, Kiyoshi, Mochida, Joji
Nat Commun, 2012-01-01;3(0):1264.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation.
Authors: Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK
Immunity, 2011-12-15;35(6):986-96.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease
Authors: Ying Chang, Jessica Nadigel, Nicholas Boulais, Jean Bourbeau, François Maltais, David H Eidelman et al.
Respiratory Research
-
Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study
Authors: Michael Lichtenauer, Michael Mildner, Konrad Hoetzenecker, Matthias Zimmermann, Bruno Karl Podesser, Wolfgang Sipos et al.
Basic Research in Cardiology
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Authors: Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E
Nat. Med., 2011-10-30;17(11):1498-503.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy.
Authors: Schreurs MP, Houston EM, May V, Cipolla MJ
FASEB J., 2011-09-12;26(1):355-62.
Species: Rat
Sample Types: In Vivo
Applications: Control -
The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Authors: Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T
Nature, 2011-08-31;477(7362):90-4.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.
Authors: Noyce RS, Bondre DG, Ha MN
PLoS Pathog., 2011-08-25;7(8):e1002240.
Species: Hamster
Sample Types: Whole Cells
Applications: Control -
FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo
Authors: Rachel Sharpe, Alex Pearson, Maria T. Herrera-Abreu, Damian Johnson, Alan Mackay, Jonathan C. Welti et al.
Clinical Cancer Research
-
Secretome Signature of Invasive Glioblastoma Multiforme
Authors: Catherine A. Formolo, Russell Williams, Heather Gordish-Dressman, Tobey J. MacDonald, Norman H. Lee, Yetrib Hathout
Journal of Proteome Research
-
Role of Interleukin 17 in Inflammation, Atherosclerosis, and Vascular Function in Apolipoprotein E–Deficient Mice
Authors: Meena S. Madhur, Samuel A. Funt, Li Li, Antony Vinh, Wei Chen, Heinrich E. Lob et al.
Arteriosclerosis, Thrombosis, and Vascular Biology
-
Inhibitory actions of Anti-Mullerian Hormone (AMH) on ovarian primordial follicle assembly.
Authors: Nilsson EE, Schindler R, Savenkova MI, Skinner MK
PLoS ONE, 2011-05-27;6(5):e20087.
Species: Rat
Sample Types: Whole Tissue
Applications: Control -
The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation.
Authors: Byrne SN, Beaugie C, O'Sullivan C, Leighton S, Halliday GM
Am. J. Pathol., 2011-05-13;179(1):211-22.
Species: Human, Mouse
Sample Types: Whole Tissue
Applications: Control -
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
J. Biol. Chem., 2011-04-22;286(23):20991-1001.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma.
Authors: Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C
PLoS Pathog., 2011-04-14;7(4):e1002016.
Species: Human
Sample Types: Whole Cells
Applications: Control -
IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
Brain Behav. Immun., 2011-03-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
Authors: Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, Tesniere A, Ibrahim N, Dechanet-Merville J, Chaput N, Smyth MJ, Kroemer G, Zitvogel L
J. Exp. Med., 2011-03-07;208(3):491-503.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells.
Authors: Yamakawa N, Uchida T, Matthay MA, Makita K
Am. J. Physiol. Lung Cell Mol. Physiol., 2011-01-21;300(4):L516-25.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression.
Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
J. Immunol., 2011-01-17;186(4):2613-22.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype.
Authors: Ouwehand K, Oosterhoff D, Breetveld M
J. Invest. Dermatol., 2010-11-11;131(2):418-25.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis.
Authors: Yoshida H, Russell J, Senchenkova EY, Almeida Paula LD, Granger DN
Am. J. Pathol., 2010-10-22;177(6):2774-81.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.
Authors: Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ
Cancer Prev Res (Phila), 2010-09-21;3(10):1222-34.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice.
Authors: Tsai M, Chen CC, Mukai K
Am. J. Pathol., 2010-09-09;177(5):2411-20.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.
Authors: Hudecek M, Schmitt TM, Baskar S
Blood, 2010-08-11;116(22):4532-41.
Species: Human
Sample Types: Whole Cells
Applications: Control -
IL-33 is produced by mast cells and regulates IgE-dependent inflammation.
Authors: Hsu CL, Neilsen CV, Bryce PJ
PLoS ONE, 2010-08-03;5(8):e11944.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling.
Authors: Tesio M, Golan K, Corso S
Blood, 2010-06-28;117(2):419-28.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells.
Authors: Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold CN, Blasius AL, Benedict CA, Moresco EM, Xia Y, Beutler B
Proc. Natl. Acad. Sci. U.S.A., 2010-05-10;107(21):9759-64.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Paternal recognition of adult offspring mediated by newly generated CNS neurons.
Authors: Mak GK, Weiss S
Nat. Neurosci., 2010-05-09;13(6):753-8.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
Authors: Cash JL, Christian AR, Greaves DR
J. Immunol., 2010-04-02;184(9):5315-24.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51.
Authors: Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME
J. Allergy Clin. Immunol., 2010-04-01;125(4):879-888.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
Authors: Heather A Himburg, Garrett G Muramoto, Pamela Daher, Sarah K Meadows, J Lauren Russell, Phuong Doan et al.
Nature Medicine
-
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
Eur. J. Immunol., 2009-12-01;39(12):3570-81.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
Authors: Reikvam H, Hatfield KJ, Oyan AM, Kalland KH, Kittang AO, Bruserud O
Eur. J. Haematol., 2009-11-17;84(3):239-51.
Species: Human
Sample Types: Whole Cells
Applications: Control -
GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche.
Authors: Shiozawa Y, Pedersen EA, Taichman RS
Exp. Hematol., 2009-11-14;38(2):132-40.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
Authors: St John AL, Abraham SN
Nat. Med., 2009-10-25;15(11):1259-65.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
Mucosal Immunol, 2009-10-07;3(1):40-8.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression.
Authors: Fujimoto H, Sangai T, Ishii G, Ikehara A, Nagashima T, Miyazaki M, Ochiai A
Int. J. Cancer, 2009-09-15;125(6):1276-84.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation.
Authors: Maeda T, Kiguchi N, Kobayashi Y, Ikuta T, Ozaki M, Kishioka S
Proc. Natl. Acad. Sci. U.S.A., 2009-07-20;106(31):13076-81.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
CCR7-CCL19/CCL21-regulated dendritic cells are responsible for effectiveness of sublingual vaccination.
Authors: Song JH, Kim JI, Kwon HJ, Shim DH, Parajuli N, Cuburu N, Czerkinsky C, Kweon MN
J. Immunol., 2009-06-01;182(11):6851-60.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway.
Authors: Weng TI, Wu HY, Lin PY, Liu SH
Infect. Immun., 2009-05-26;77(8):3312-9.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor.
Authors: Verbout NG, Jacoby DB, Gleich GJ, Fryer AD
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-05-15;297(2):L228-37.
Species: Guinea Pig
Sample Types: In Vivo
Applications: Control -
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Vascular endothelial growth factor-induced chemotaxis and IL-10 from T cells.
Authors: Shin JY, Yoon IH, Kim JS, Kim B, Park CG
Cell. Immunol., 2009-02-26;256(1):72-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells.
Authors: Brounais B, David E, Chipoy C, Trichet V, Ferre V, Charrier C, Duplomb L, Berreur M, Redini F, Heymann D, Blanchard F
Bone, 2009-01-03;44(5):830-9.
Species: Mouse, Rat
Sample Types: Cell Lysates
Applications: Control -
CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis.
Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S
Eur. J. Immunol., 2008-11-01;38(11):3050-9.
Species: Human
Sample Types: Ex Vivo
Applications: Control -
Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint.
Arthritis Rheum., 2008-11-01;58(0):3377-87.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo.
Authors: Sakatani S, Seto-Ohshima A, Shinohara Y, Yamamoto Y, Yamamoto H, Itohara S, Hirase H
J. Neurosci., 2008-10-22;28(43):10928-36.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Fibroblast-type reticular stromal cells regulate the lymph node vasculature.
Authors: Chyou S, Ekland EH, Carpenter AC, Tzeng TC, Tian S, Michaud M, Madri JA, Lu TT
J. Immunol., 2008-09-15;181(6):3887-96.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo.
Authors: Chen W, Tabata Y, Gibson AM, Daines MO, Warrier MR, Wills-Karp M, Hershey GK
J. Allergy Clin. Immunol., 2008-08-09;122(3):625-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.
Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V
Blood, 2008-07-29;112(8):3154-63.
Species: Human
Sample Types: Whole Cells
Applications: Control -
The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice.
Authors: Kiguchi N, Maeda T, Kobayashi Y, Kondo T, Ozaki M, Kishioka S
Eur. J. Pharmacol., 2008-07-10;592(1):87-92.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas.
Authors: Held-Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo HH, Ludwig A, Mehdorn HM
Glia, 2008-05-01;56(7):764-74.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Regulation of scar formation by vascular endothelial growth factor.
Authors: Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, DiPietro LA
Lab. Invest., 2008-04-21;88(6):579-90.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Authors: Jacobsen LC, Sorensen OE, Cowland JB, Borregaard N, Theilgaard-Monch K
J. Leukoc. Biol., 2008-02-19;83(5):1155-64.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha.
Authors: Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, Wang P, Messina JL
Endocrinology, 2008-01-10;149(5):2369-82.
Species: Rat
Sample Types: In Vivo
Applications: Control -
Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation.
Authors: Chandrasekar B, Patel DN, Mummidi S, Kim JW, Clark RA, Valente AJ
J. Biol. Chem., 2007-12-17;283(7):4200-9.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Control -
Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
Nature, 2007-12-06;450(7171):825-31.
Species: Mouse
Sample Types: Cell Lysates
Applications: Control -
12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells.
Authors: Jang BC, Park YK, Choi IH, Kim SP, Hwang JB, Baek WK, Suh MH, Mun KC, Suh SI
Int. J. Oncol., 2007-12-01;31(6):1439-47.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Amelioration of coxsackievirus B3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1.
Authors: Crocker SJ, Frausto RF, Whitmire JK, Benning N, Milner R, Whitton JL
Am. J. Pathol., 2007-11-30;171(6):1762-73.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxia.
Authors: Yeh WL, Lin CJ, Fu WM
Mol. Pharmacol., 2007-10-17;73(1):170-7.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
Crit. Care Med., 2007-09-01;35(9):2156-63.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions.
Authors: Advani A, Kelly DJ, Advani SL, Cox AJ, Thai K, Zhang Y, White KE, Gow RM, Marshall SM, Steer BM, Marsden PA, Rakoczy PE, Gilbert RE
Proc. Natl. Acad. Sci. U.S.A., 2007-08-28;104(36):14448-53.
Species: Rat
Sample Types: In Vivo
Applications: Control -
Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor.
Authors: Colston JT, de la Rosa SD, Koehler M, Gonzales K, Mestril R, Freeman GL, Bailey SR, Chandrasekar B
Am. J. Physiol. Heart Circ. Physiol., 2007-07-06;293(3):H1839-46.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
Distribution of the receptor for advanced glycation end products in the human male reproductive tract: prevalence in men with diabetes mellitus.
Authors: Mallidis C, Agbaje I, Rogers D, Glenn J, McCullough S, Atkinson AB, Steger K, Stitt A, McClure N
Hum. Reprod., 2007-06-21;22(8):2169-77.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain.
Authors: Clark AK, Yip PK, Grist J, Gentry C, Staniland AA, Marchand F, Dehvari M, Wotherspoon G, Winter J, Ullah J, Bevan S, Malcangio M
Proc. Natl. Acad. Sci. U.S.A., 2007-06-05;104(25):10655-60.
Species: Rat
Sample Types: In Vivo
Applications: Control -
CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses.
Authors: Calvert JG, Slade DE, Shields SL, Jolie R, Mannan RM, Ankenbauer RG, Welch SK
J. Virol., 2007-05-09;81(14):7371-9.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Control -
Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets.
Authors: Xanthou G, Alissafi T, Semitekolou M, Simoes DC, Economidou E, Gaga M, Lambrecht BN, Lloyd CM, Panoutsakopoulou V
Nat. Med., 2007-04-15;13(5):570-8.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor.
Authors: Skibinski G, Elborn JS, Ennis M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-03-23;293(1):L69-76.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth.
Authors: Chen H, Gordon MS, Campbell RA, Li M, Wang CS, Lee HJ, Sanchez E, Manyak SJ, Gui D, Shalitin D, Said J, Chang Y, Deuel TF, Baritaki S, Bonavida B, Berenson JR
Blood, 2007-03-16;110(1):287-95.
Species: Human
Sample Types: Whole Cells
Applications: Control -
The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.
Authors: Fuller GL, Williams JA, Tomlinson MG, Eble JA, Hanna SL, Pohlmann S, Suzuki-Inoue K, Ozaki Y, Watson SP, Pearce AC
J. Biol. Chem., 2007-03-05;282(17):12397-409.
Species: Chicken
Sample Types: Whole Cells
Applications: Control -
Vascular-derived artemin: a determinant of vascular sympathetic innervation?
Authors: Damon DH, Teriele JA, Marko SB
Am. J. Physiol. Heart Circ. Physiol., 2007-03-02;293(1):H266-73.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.
Authors: Zhong L, Bradley J, Schubert W, Ahmed E, Adamis AP, Shima DT, Robinson GS, Ng YS
Invest. Ophthalmol. Vis. Sci., 2007-03-01;48(3):1212-8.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
J. Immunol., 2007-02-15;178(4):2018-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.
Authors: Withers DR, Fiorini C, Fischer RT, Ettinger R, Lipsky PE, Grammer AC
Blood, 2007-02-13;109(11):4856-64.
Species: Human
Sample Types: Whole Cells
Applications: Control -
IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells.
Authors: Gleissner CA, Zastrow A, Klingenberg R, Kluger MS, Konstandin M, Celik S, Haemmerling S, Shankar V, Giese T, Katus HA, Dengler TJ
Eur. J. Immunol., 2007-01-01;37(1):177-92.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage.
Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH
J. Mol. Cell. Cardiol., 2006-12-16;42(3):620-30.
Species: Rat
Sample Types:
Applications: Control -
CCL2 regulates angiogenesis via activation of Ets-1 transcription factor.
Authors: Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV
J. Immunol., 2006-08-15;177(4):2651-61.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Induction of interleukin-6 by hepatitis C virus core protein in hepatitis C-associated mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma.
Authors: Feldmann G, Nischalke HD, Nattermann J, Banas B, Berg T, Teschendorf C, Schmiegel W, Duhrsen U, Halangk J, Iwan A, Sauerbruch T, Caselmann WH, Spengler U
Clin. Cancer Res., 2006-08-01;12(15):4491-8.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
Authors: Daryadel A, Grifone RF, Simon HU, Yousefi S
J. Biol. Chem., 2006-07-21;281(37):27653-61.
Species: Human
Sample Types: Whole Cells
Applications: Control -
TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells.
Authors: Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B
Biochem. Biophys. Res. Commun., 2006-07-13;347(4):1113-20.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions.
Authors: Cahill RA, Wang JH, Soohkai S, Redmond HP
Surgery, 2006-07-01;140(1):108-12.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration.
Authors: Li Y, Fan J, Chen M, Li W, Woodley DT
J. Invest. Dermatol., 2006-05-11;126(9):2096-105.
Species: Human
Sample Types: Serum
Applications: Control -
Junctional adhesion molecule 1 is a functional receptor for feline calicivirus.
Authors: Makino A, Shimojima M, Miyazawa T, Kato K, Tohya Y, Akashi H
J. Virol., 2006-05-01;80(9):4482-90.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
Authors: Nguyen AN, Stebbins EG, Henson M, O&apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
Exp. Cell Res., 2006-04-04;312(10):1909-23.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes.
Authors: Koelle DM, Huang J, Hensel MT, McClurkan CL
J. Virol., 2006-03-01;80(6):2863-72.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage.
Authors: Yang S, Hu S, Hsieh YC, Choudhry MA, Rue LW, Bland KI, Chaudry IH
J. Mol. Cell. Cardiol., 2006-02-24;40(4):570-9.
Species: Rat
Sample Types:
Applications: Control -
The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
Authors: Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
J. Allergy Clin. Immunol., 2005-12-02;117(1):103-10.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
Authors: Carpenter KJ, Hogaboam CM
Infect. Immun., 2005-11-01;73(11):7198-207.
Species: Mouse
Sample Types:
Applications: Control -
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005-11-01;175(9):6177-89.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Requirement for intercellular adhesion molecule 1 and caveolae in invasion of human oral epithelial cells by Porphyromonas gingivalis.
Authors: Tamai R, Asai Y, Ogawa T
Infect. Immun., 2005-10-01;73(10):6290-8.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Maladaptive role of IL-6 in ischemic acute renal failure.
Authors: Kielar ML, John R, Bennett M
J. Am. Soc. Nephrol., 2005-09-28;16(11):3315-25.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2.
Authors: Sakamoto E, Hato F, Kato T, Sakamoto C, Akahori M, Hino M, Kitagawa S
J. Leukoc. Biol., 2005-04-21;78(1):301-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Protection of human conjunctival fibroblasts from NO-induced apoptosis by interleukin-4 or interleukin-13.
Authors: Fujitsu Y, Fukuda K, Kimura K, Seki K, Kumagai N, Nishida T
Invest. Ophthalmol. Vis. Sci., 2005-03-01;46(3):797-802.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
Authors: Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA
J. Thromb. Haemost., 2005-02-23;3(4):733-41.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
J. Immunol., 2005-02-15;174(4):2376-86.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Variation in macrophage-migration-inhibitory-factor immunoreactivity during porcine gestation.
Authors: Paulesu L, Cateni C, Romagnoli R, Ietta F, Dantzer V
Biol. Reprod., 2004-11-24;72(4):949-53.
Species: Human, Porcine
Sample Types: Whole Tissue
Applications: Control -
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages.
Authors: Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M
J. Gen. Virol., 2004-09-01;85(0):2603-13.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
J. Immunol., 2004-05-01;172(9):5213-21.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
J. Immunol., 2004-05-01;172(9):5753-64.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Control -
Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype.
Authors: Leach RE, Kilburn B, Wang J, Liu Z, Romero R, Armant DR
Dev. Biol., 2004-02-15;266(2):223-37.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells.
Authors: Dimitriadis E, Robb L, Salamonsen LA
Mol. Hum. Reprod., 2002-07-01;8(7):636-43.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice.
Authors: Cashman J, Clark-Lewis I, Eaves A, Eaves C
Blood, 2002-02-01;99(3):792-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment.
Authors: Janatpour MJ, Hudak S, Sathe M, McEvoy LM
J. Exp. Med., 2001-11-05;194(9):1375-84.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.
Authors: Bertero A, Fields P A et al.
J Cell Biol
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OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators
Authors: Valente AJ, Irimpen AM, Siebenlist U et al.
Free Radic Biol Med
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Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors
Authors: NB Nataraj, A Noronha, JS Lee, S Ghosh, HR Mohan Raju, A Sekar, B Zuckerman, M Lindzen, E Tarcitano, S Srivastava, M Selitrenni, I Livneh, D Drago-Garc, O Rueda, C Caldas, S Lev, T Geiger, A Ciechanove, I Ulitsky, R Seger, E Ruppin, Y Yarden
Cell Reports, 2022-02-22;38(8):110418.
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Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression
Oncogene, 2016-02-15;35(36):4741-51.
-
ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death
Authors: M Ueno, T Shiomi, S Mochizuki, M Chijiiwa, M Shimoda, Y Kanai, F Kataoka, A Hirasawa, N Susumu, D Aoki, Y Okada
Cancer Sci., 2018-02-01;109(2):471-482.
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LeIF: a recombinant Leishmania protein that induces an IL-12-mediated Th1 cytokine profile.
Authors: Skeiky YA, Kennedy M, Kaufman D
J. Immunol., 1998-12-01;161(11):6171-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation
Authors: M Subileau, G Merdzhanov, D Ciais, V Collin-Fau, JJ Feige, S Bailly, D Vittet
Stem Cell Reports, 2018-12-27;0(0):.
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Molecular signaling pathways mediating osteoclastogenesis induced by prostate cancer cells.
Authors: Rafiei S, Komarova S
BMC Cancer, 2013-12-26;13(0):605.
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PRC2-mediated epigenetic suppression of type I IFN-STAT2 signaling impairs antitumor immunity in luminal breast cancer
Authors: J Hong, JH Lee, Z Zhang, Y Wu, M Yang, Y Liao, R de la Rosa, J Scheirer, D Pechacek, N Zhang, Z Xu, T Curiel, X Tan, TH Huang, K Xu
Cancer Research, 2022-12-16;0(0):.
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Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
Authors: Lachlan Harris
Development, 2016-12-15;143(24):4620-4630.
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The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue
Authors: KR Grau, AN Roth, S Zhu, A Hernandez, N Colliou, BB DiVita, DT Philip, C Riffe, B Giasson, SM Wallet, M Mohamadzad, SM Karst
Nat Microbiol, 2017-11-06;0(0):.
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RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production
Authors: JK Sprokholt, TM Kaptein, JL van Hamme, RJ Overmars, SI Gringhuis, TBH Geijtenbee
PLoS Pathog., 2017-11-29;13(11):e1006738.
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Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson's disease: removing axonal debris
Authors: Morales I, Puertas-Avendano R, Sanchez A Et al.
Translational neurodegeneration
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IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients.
Authors: Pennino D, Bhavsar P, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham S, Cavani A, Eyerich K, Chung K, Schmidt-Weber C, Eyerich S
J Allergy Clin Immunol, 2012-11-19;131(2):562-70.
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Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery
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Normal goat IgG control was used as an isotype control @ 2.5 ug/ml in a FITC-mediated permeability assay in transwells.
Neuronal cultures were incubated with fresh media (control) or with NA 10µM. Three hours later, the media were replaced with half the volume of fresh ones and incubated for five hours. The resultant neuronal conditioned media (CM) were transferred to microglia cultures alone or in combination with a neutralizing antibody (Ab) against CX3CL1 (10µg/ml) or with normal goat IgG. Five hours after the addition of CM, 1µl of LPS (final concentration 0.1 µg/ml) or water was added to all culture wells and incubated for 24h. The concentration of nitrites in the culture media was measured in microglial media.
Results published in:
Article title: Noradrenaline induces CX3CL1 production and release by neurons
Article reference: NP6524
Journal title: Neuropharmacology
Final version published online: 08-Dec-2016
DOI information: 10.1016/j.neuropharm.2016.12.001
Used for both FACS and IF. Worked well for both.