Oxymetazoline hydrochloride
Discontinued Product
Chemical Name: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride
Purity: ≥99%
Biological Activity
Partial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Cardiovascular effects of oxymetazoline and UK14,304 in conscious and pithed rats.
Bayorh et al.
Clin.Exp.Hypertens., 1997;19:445 -
Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes.
Horie et al.
Br.J.Pharmacol., 1995;116:1611 -
Interaction of the α-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors.
Schoeffter et al.
Eur.J.Pharmacol., 1991;196:213
Product Datasheets
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Citations for Oxymetazoline hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Oxymetazoline hydrochloride include:
2 Citations: Showing 1 - 2
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A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.
Authors: Schihada Et al.
Commun Biol 2018;1:105
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An Alpha-1A Adrenergic Receptor Agonist Prevents Acute dox. Cardiomyopathy in Male Mice.
Authors: Montgomery
Plos One 2017;12:e0168409
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