Oxytocin
Purity: ≥95%
Biological Activity
Oxytocin is a neurohypophyseal peptide. Stimulates uterine contraction and lactation.Technical Data
(Modifications: Gly-9 = C-terminal amide, disulfide bridge: 1-6)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Vasopressin and oxyt. receptors in the central nervous system.
Barberis and Tribolle
Crit.Rev.Neurobiol., 1996;10:119 -
Signal transduction pathways of the human V1-vascular V2-renal, V3-pituitary vasopressin and oxyt. receptors.
Thibonnier et al.
Prog.Brain Res., 1998;119:147
Product Datasheets
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Citations for Oxytocin
The citations listed below are publications that use Tocris products. Selected citations for Oxytocin include:
6 Citations: Showing 1 - 6
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Central and peripheral GLP-1 systems independently and additively suppress eating.
Authors: Brierley Et al.
Nat Metab 2021;3:258
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OXT can regulate myometrial smooth muscle excitability by inhibiting the Na+ -activated K+ channel, Slo2.1.
Authors: Ferreira Et al.
J Physiol 2019;597:137
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OXT functions as a spatiotemporal filter for excitatory synaptic inputs to VTA DA neurons.
Authors: Xiao Et al.
Elife 2018;7
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Targeted Interneuron Depletion in the Dorsal Striatum Produces Autism-like Behavioral Abnormalities in Male but Not Female Mice.
Authors: Rapanelli Et al.
Biol Psychiatry 2017;82:194
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The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Authors: Nøhr Et al.
Neurochem Int 2017;102:105
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Serotonergic neuron regulation informed by in vivo single-cell transcriptomics.
Authors: Spaethling Et al.
Hypertension 2014;28:771
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