PACAP 1-27
Purity: ≥95%
Biological Activity
PACAP 1-27 is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase.Technical Data
(Modifications: Leu-27 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Pituitary adenylate cyclase-activating polypeptide-27 causes a biphasic chronotropic effect and atrial fibrillation in autonomically decentralized, anaesthetized dogs.
Hirose et al.
J.Pharmacol.Exp.Ther., 1997;283:478 -
XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.
Michel et al.
Pharmacol.Rev., 1998;50:143 -
Pituitary adenylate cyclase-activating polypeptide increase [Ca2+]i in rat gonadotrophs through an inositol trisphosphate-dependent mechanism.
Rawlings et al.
J.Biol.Chem., 1994;269:5680
Product Datasheets
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Citation for PACAP 1-27
The citations listed below are publications that use Tocris products. Selected citations for PACAP 1-27 include:
1 Citation: Showing 1 - 1
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Sonic hedgehog expression in the postnatal brain.
Authors: Rivell Et al.
Biol Open 2019;8
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