(±)-Palmitoylcarnitine chloride
Description: Intermediate in fatty acid oxidation
Biological Activity
(±)-Palmitoylcarnitine chloride is an intermediate in mitochondrial fatty acid oxidation. Has a wide range of biological actions including the inhibition of protein kinase C and cell membrane disruption.Technical Data
M.Wt:
436.07
Formula:
C23H46ClNO4
Solubility:
Soluble to 25 mM in water
Storage:
Desiccate at RT
CAS No:
6865-14-1
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
The effects of novel vasodilator long chain acyl carnitine esters in the isolated perfused heart of the rat.
Criddle et al.
Br.J.Pharmacol., 1990;99:477 -
Interactions of palmitoyl carnitine with the endothelium in rat aorta.
Dainty et al.
Br.J.Pharmacol., 1990;100:241 -
Modulation by palmitoylcarnitine of protein kinase C activation.
Nakadate and Blumberg
Cancer Res., 1987;47:6537 -
The membrane-perturbing properties of palmitoyl-coenzyme A and palmitoylcarnitine. A comparative study.
Requero et al.
Biochemistry, 1995;34:10400
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