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PD 4'-piperazine

Catalog #: 7859 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7859/50
PD 4'-piperazine | Degrader Building Blocks
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Description: Stable cereblon ligand, for PROTAC synthesis

Chemical Name: Dihydro-1-[4-(1-piperazinyl)phenyl]-2,4(1H,3H)-pyrimidinedione dihydrochloride

Purity: ≥95%

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Biological Activity

PD 4'-piperazine is a cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PD-PROTAC molecules that exhibit improved stability and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
347.24
Formula:
C14H18N4O2.2HCl
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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