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Phentolamine Mesylate

Catalog #: 6431
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6431/100
Phentolamine Mesylate | CAS No. 65-28-1 | Adrenergic alpha-1 Receptor Antagonists
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Description: Adrenergic α receptor antagonist; antihypertensive

Chemical Name: 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol methanesulfonate

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Phentolamine Mesylate is a non-selective adrenergic α receptor antagonist (pKB = 8.07). Intravenous injection causes hypotension and tachycardia in rats. Intraperitoneal injection in mice increases plasma FGF21 levels.

Technical Data

M.Wt:
377.46
Formula:
C17H19N3O.CH4O3S
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
65-28-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Phentolamine Mesylate

The citations listed below are publications that use Tocris products. Selected citations for Phentolamine Mesylate include:

2 Citations: Showing 1 - 2

  1. Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors.
    Authors: Kira E Et al.
    Cell Rep  2022;40:111426
  2. Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux.
    Authors: David R Et al.
    Front Oncol  2021;10:614288

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