Home / Voltage-gated Sodium Channel Modulators / Phrixotoxin 3

Phrixotoxin 3

Catalog #: 4914 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4914/100U
Phrixotoxin 3
1 Image
Description: Potent blocker of NaV1.2, NaV1.3 and NaV1.5 channels

Purity: ≥95%

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Biological Activity

Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels (IC50 values are 0.6, 42, and 72 nM for NaV1.2, NaV1.3 and NaV1.5 respectively). Blocks inward sodium currents in a voltage-dependent manner.

Technical Data

M.Wt:
4059.74
Formula:
C176H269N51O48S6
Sequence:
DCLGFLWKCNPSNDKCCRPNLVCSRKDKWCKYQI

(Modifications: Disulfide bridges: 2-17, 9-23, 16-30)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
880886-00-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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