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PLpro inhibitor 19

Catalog #: 7505 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7505/5
PLpro inhibitor 19 | CAS No. 2863607-73-0 | Papain-like Protease
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Description: SARS-CoV-2 PLpro and replication inhibitor

Chemical Name: (R)-N-(3-Fluoro-5-((1-(1-(naphthalen-1-yl)ethyl)piperidine-4-carboxamido)methyl)phenyl)-4-methylpiperazine-1-carboxamide

Purity: ≥98%

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Biological Activity

PLpro inhibitor 19 is a SARS-CoV-2 inhibitor that inhibits viral replication and PLpro enzymatic activity in vitro (IC50 values are 0.18 μM and 0.44 μM respectively). PLpro inhibitor 19 is selective for PLpro over human deubiquitinating enzymes (DUBs) and DUB-like proteases and displays no cytotoxicity at up to 10 μM.

Technical Data

M.Wt:
531.68
Formula:
C31H38FN5O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2863607-73-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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