PMPA (NAALADase inhibitor)

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1380/10 Contact your distributor for availability.10 mg / Please Inquire
1380/50 Contact your distributor for availability.50 mg / Please Inquire
PMPA (NAALADase inhibitor) | CAS No. 173039-10-6 | Carboxypeptidase Inhibitors
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Description: GCP II inhibitor

Chemical Name: 2-(Phosphonomethyl)pentane-1,5-dioic acid

Product Details
Citations (1)
Reviews

Biological Activity

PMPA (NAALADase inhibitor) is a highly potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/N-acetylated α-linked dipeptidase/NAALADase) with a Ki value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).

Technical Data

M.Wt:
226.12
Formula:
C6H11O7P
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at RT
CAS No:
173039-10-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca Ltd.

Product Datasheets

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Citation for PMPA (NAALADase inhibitor)

The citations listed below are publications that use Tocris products. Selected citations for PMPA (NAALADase inhibitor) include:

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