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Proteome Profiler Human Phospho-MAPK Array Kit

Catalog #: ARY002B
102 Citations 2 Reviews Datasheet / COA / SDS

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R&D Systems Proteome Profiler Antibody Array Kits
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Proteome Profiler Human Phospho-MAPK Array Kit Summary

Proteome Profiler™ Human Phospho-MAPK Array Kit

A membrane-based antibody array for the parallel determination of the relative phosphorylation of human mitogen-activated protein kinases.

Contains 4 membranes - each spotted in duplicate with 26 different MAPK antibodies.

Validated for analyte detection in cell lysates.

Troubleshooting Guide

Key Benefits

  • Detects phosphorylation of 26 human kinases simultaneously
  • Requires no specialized equipment

View Data Examples
 
 

Principle of the Assay

The Proteome Profiler Human Phospho-MAPK Array Kit is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated phospho-specific detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount phosphorylation in the bound analyte.

Why Use an Antibody Array to Detect Receptor Phosphorylation?

Determining the phosphorylation of multiple kinases in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple phosphorylations in a single sample can be cost-effective and also save time and sample.

 

Kit Contents
  • 4-Array Membranes
  • 4-Well Multi-dish
  • Lysis Buffer
  • Array Buffers
  • Wash Buffer
  • Detection Antibody Cocktail
  • Streptavidin-HRP
  • Chemiluminescent Detection Reagents
  • Transparency Overlay Template
  • Detailed product datasheet with protocol

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

Simultaneously detect the relative phosphorylation of these of these kinases in a single sample.
Akt1 HSP27 p38 beta
Akt2 JNK1 p38 delta
Akt3 JNK2 p38 gamma
Akt pan JNK3 p53
CREB JNK pan p70 S6K
ERK1 MKK3 RSK1
ERK2 MKK6 RSK2
GSK-3 alpha/beta MSK2 TOR
GSK-3 beta p38 alpha  

Assays for analytes represented in the Human Phospho-MAPK Array Kit

Analyte DuoSet® IC ELISA Development System (Total) DuoSet® IC ELISA Development Systems (Phospho) Cell-based ELISA Kits Surveyor™ IC ELISA Kits
Akt1 (S473) DYC1775 DYC2289C    
Akt2 (S474) DYC2315      
Akt3 (S472)        
Akt pan (S473, S474, S472) DYC887B KCB887 SUV887B  
CREB (S133)   DYC2510 KCB2510  
ERK1 (T202/Y204) DYC1940 DYC1825 KCB1018 SUV1018B
JNK1 (T183/Y185)        
JNK2 (T183/Y185) DYC1846 DYC2236    
JNK3 (T221/Y223)        
JNK pan (T183/Y185, T221/Y223) DYC1205 DYC1387 KCB1205  
MKK3 (S218/T222)   DYC5585    
MKK6 (S207/T211)   DYC5586    
MSK2 (S360)        
p38 alpha (T180/Y182) DYC8691B DYC869B KCB869 SUV869B
p38 beta (T180/Y182)     KCB869  
p38 delta (T180/Y182) DYC2124 DYC2124 KCB869  
p38 gamma (T183/Y185)   DYC1664    
p53 (S46) DYC1043 DYC1489    
p70 S6K (T421/S424) DYC8962 DYC8965    
RSK1 (S380)   DYC892B    
RSK2 (S386)        
TOR (S2448)   DYC1665   SUV1665
Stability and Storage

Store the unopened kit at 2°C to 8°C. Do not use past kit expiration date.

 

Data Examples
Figure 1.
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Figure 1.HeLa human cervical epithelial carcinoma cells were either untreated or exposed to 150 J/m2 of UV light followed by a 30 minute recovery period before lysis. Data shown are from a 2 minute exposure to X-ray film.
Figure 2
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Figure 2. : MCF-7 human breast cancer cells were either untreated or treated with 100 ng/mL of rhIGF-I (R&D Systems, Catalog # 291-G1) for 1 hour. Cells for rhIGF-I treatment either received a 1 hour pre-treatment with the PI3K inhibitor, LY294002, or received no pre-treatment. Data shown are from a 6 minute exposure to X-ray film.

BG01V human embryonic stem cells are licensed from ViaCyte, Inc.

 

Image Analysis Software

Quick Spots image analysis software

R&D Systems® now offers Quick Spots image analysis software designed specifically for your Proteome Profiler™ Arrays.

No more laborious set-up of templates in other imaging software, Quick Spots contains preloaded templates for each Proteome Profiler™ array. It knows where your results should be, and provides the data in less time and with less work.

Simplify your workflow today.

*Clicking on this button will navigate you away from the R&D Systems® website. Quick Spots image analysis software can be purchased through Western Vision Software.

 

Specifications

Source
N/A
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Human

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Citations for Proteome Profiler Human Phospho-MAPK Array Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

102 Citations: Showing 1 - 10
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  1. Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
    Authors: RJ da Silva-O, INF Gomes, LS da Silva, AVH Lengert, AC Laus, ME Melendez, CC Munari, FP Cury, GB Longato, RM Reis
    International Journal of Molecular Sciences, 2022-07-14;23(14):.  2022-07-14
  2. Aberrantly reduced expression of miR-342-5p contributes to CCND1-associated chronic myeloid leukemia progression and imatinib resistance
    Authors: YY Wu, HF Lai, TC Huang, YG Chen, RH Ye, PY Chang, SW Lai, YC Chen, CH Lee, WN Liu, MS Dai, JH Chen, CL Ho, YL Chiu
    Cell Death & Disease, 2021-10-05;12(10):908.  2021-10-05
  3. Effects of different ischemic preconditioning strategies on physiological and cellular mechanisms of intestinal ischemia/reperfusion injury: Implication from an isolated perfused rat small intestine model
    Authors: YL Wong, I Lautenschl, L Hummitzsch, K Zitta, F Cossais, T Wedel, R Rusch, R Berndt, M Gruenewald, N Weiler, M Steinfath, M Albrecht
    PLoS ONE, 2021-09-03;16(9):e0256957.  2021-09-03
  4. Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
    Authors: A Whitehead, FN Krause, A Moran, ADV MacCannell, JL Scragg, BD McNally, E Boateng, SA Murfitt, S Virtue, J Wright, J Garnham, GR Davies, J Dodgson, JE Schneider, AJ Murray, C Church, A Vidal-Puig, KK Witte, JL Griffin, LD Roberts
    Nature Communications, 2021-03-26;12(1):1905.  2021-03-26
  5. Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations
    Authors: B Royer-Poko, MA Busch, S Tenbusch, M Schmidt, M Beier, AD Woods, H Thiele, J Mora
    Cancers, 2020-12-28;13(1):.  2020-12-28
  6. LIMD2 Regulates Key Steps of Metastasis Cascade in Papillary Thyroid Cancer Cells via MAPK Crosstalk
    Authors: RP Araldi, TC de Melo, D Levy, DM de Souza, B Maurício, GA Colozza-Ga, SP Bydlowski, H Peng, FJ Rauscher, JM Cerutti
    Cells, 2020-11-23;9(11):.  2020-11-23
  7. Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway
    Authors: X Shi, M Xiao, Z Xie, Q Shi, Y Zhang, JW Leavenwort, B Yan, H Huang
    Parasit Vectors, 2020-04-08;13(1):183.  2020-04-08
  8. The roles of mechanosensitive ion channels and associated downstream MAPK signaling pathways in PDLC mechanotransduction
    Authors: Y Shen, Y Pan, S Guo, L Sun, C Zhang, L Wang
    Mol Med Rep, 2020-02-27;0(0):.  2020-02-27
  9. Serial Xenotransplantation in NSG Mice Promotes a Hybrid Epithelial/Mesenchymal Gene Expression Signature and Stemness in Rhabdomyosarcoma Cells
    Authors: J Skoda, J Neradil, I Staniczkov, A Nunukova, P Macsek, K Borankova, V Dobrotkova, P Nemec, J Sterba, R Veselska
    Cancers (Basel), 2020-01-13;12(1):.  2020-01-13
  10. Mechanisms of entrectinib resistance in a neuroblastoma xenograft model
    Authors: SP MacFarland, K Naraparaju, R Iyer, P Guan, V Kolla, Y Hu, K Tan, GM Brodeur
    Mol. Cancer Ther., 2019-12-23;0(0):.  2019-12-23
  11. The anti-inflammatory agent bindarit acts as a modulator of fatty acid-binding protein 4 in human monocytic cells
    Authors: S Oddi, L Scipioni, A Totaro, C Angelucci, B Dufrusine, A Sabatucci, D Tortolani, I Coletta, MA Alisi, L Polenzani, M Assfalg, C Caltagiron, E Dainese, M Maccarrone
    Sci Rep, 2019-10-22;9(1):15155.  2019-10-22
  12. Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells
    Authors: R Russo, N Matrone, V Belli, D Ciardiello, M Valletta, S Esposito, PV Pedone, F Ciardiello, T Troiani, A Chambery
    Cancers (Basel), 2019-09-25;11(10):.  2019-09-25
  13. Evaluation of Tumor Cell-Tumor Microenvironment Component Interactions as Potential Predictors of Patient Response to Napabucasin
    Authors: AY Chang, E Hsu, J Patel, Y Li, M Zhang, H Iguchi, HA Rogoff
    Mol. Cancer Res., 2019-05-01;0(0):.  2019-05-01
  14. Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach
    Authors: Z Xiao, B Sperl, S Gärtner, T Nedelko, E Stacher-Pr, A Ullrich, PG Knyazev
    Oncotarget, 2019-04-02;10(26):2546-2560.  2019-04-02
  15. Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts
    Authors: T Masuda, T Nakashima, M Namba, K Yamaguchi, S Sakamoto, Y Horimasu, S Miyamoto, H Iwamoto, K Fujitaka, Y Miyata, H Hamada, M Okada, N Hattori
    J. Cell. Mol. Med., 2019-02-07;0(0):.  2019-02-07
  16. Mechanical exposure and diacerein treatment modulates integrin-FAK-MAPKs mechanotransduction in human osteoarthritis chondrocytes
    Authors: B Lohberger, H Kaltenegge, L Weigl, A Mann, W Kullich, N Stuendl, A Leithner, B Steinecker
    Cell. Signal., 2018-12-21;56(0):23-30.  2018-12-21
  17. The small organic molecule C19 binds and strengthens the KRAS4b-PDE? complex and inhibits growth of colorectal cancer cells in vitro and in vivo
    Authors: P Cruz-Nova, M Schnoor, J Correa-Bas, M Bello, P Briseño-Di, A Rojo-Domín, CM Ortiz-Mend, J Guerrero-A, FJ García-Váz, R Hernández-, MDR Thompson-B, M Vargas
    BMC Cancer, 2018-11-01;18(1):1056.  2018-11-01
  18. Effects of Sunitinib and Other Kinase Inhibitors on Cells Harboring a PDGFRB Mutation Associated with Infantile Myofibromatosis
    Authors: M Sramek, J Neradil, P Macigova, P Mudry, K Polaskova, O Slaby, H Noskova, J Sterba, R Veselska
    Int J Mol Sci, 2018-09-01;19(9):.  2018-09-01
  19. Resveratrol-Linoleate protects from exacerbated endothelial permeability via a �drastic inhibition of the MMP-9 activity
    Authors: A Shamseddin, C Crauste, E Durand, P Villeneuve, G Dubois, T Pavlickova, T Durand, J Vercautere, F Veas
    Biosci. Rep., 2018-07-31;0(0):.  2018-07-31
  20. Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs
    Authors: B Haas, V Klinger, C Keksel, V Bonigut, D Kiefer, J Caspers, J Walther, M Wos-Magang, S Weickhardt, G Röhn, M Timmer, R Frötschl, N Eckstein
    Cancer Cell Int., 2018-05-04;18(0):69.  2018-05-04
  21. Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity
    Authors: Y Koizumi, K Nagai, L Gao, S Koyota, T Yamaguchi, M Natsui, Y Imai, K Hasumi, T Sugiyama, K Kuba
    Sci Rep, 2018-04-03;8(1):5472.  2018-04-03
  22. The role of atorvastatin in suppressing tumor growth of uterine fibroids
    Authors: Z Shen, S Li, B Sheng, Q Shen, LZ Sun, H Zhu, X Zhu
    J Transl Med, 2018-03-09;16(1):53.  2018-03-09
  23. Overexpression of the 14-3-3? protein in uterine leiomyoma cells results in growth retardation and increased apoptosis
    Authors: Q Shen, X Hu, L Zhou, S Zou, LZ Sun, X Zhu
    Cell. Signal., 2018-01-31;45(0):43-53.  2018-01-31
  24. Isolation and characterization of a new naturally immortalized human breast carcinoma cell line, KAIMRC1
    Authors: R Ali, N Samman, H Al Zahrani, A Nehdi, S Rahman, AL Khan, M Al Balwi, LA Alriyees, M Alzaid, A Al Askar, M Boudjelal
    BMC Cancer, 2017-11-29;17(1):803.  2017-11-29
  25. Lipoprotein(a) Induces Human Aortic Valve Interstitial Cell Calcification
    Authors: B Yu, A Hafiane, G Thanassoul, L Ott, N Filwood, M Cerruti, O Gourgas, D Shum-Tim, H Al Kindi, B de Varenne, A Alsheikh-A, J Genest, A Schwertani
    JACC Basic Transl Sci, 2017-08-28;2(4):358-371.  2017-08-28
  26. Survival of head and neck cancer cells relies upon LZK kinase-mediated stabilization of mutant p53
    Authors: ZC Edwards, EW Trotter, P Torres-Ayu, P Chapman, HM Wood, K Nyswaner, J Brognard
    Cancer Res., 2017-07-31;0(0):.  2017-07-31
  27. Effects of Secreted Mast Cell Mediators on Retinal Pigment Epithelial Cells: Focus on Mast Cell Tryptase
    Authors: R Arai, A Usui-Ouchi, Y Ito, K Mashimo, A Murakami, N Ebihara
    Mediators Inflamm., 2017-06-29;2017(0):3124753.  2017-06-29
  28. Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes
    Authors: M Mustapic, E Eitan, JK Werner, ST Berkowitz, MP Lazaropoul, J Tran, EJ Goetzl, D Kapogianni
    Front Neurosci, 2017-05-22;11(0):278.  2017-05-22
  29. HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype
    Authors: NPY Chung, X Ou, KMF Khan, J Salit, RJ Kaner, RG Crystal
    Cell Rep, 2017-05-09;19(6):1091-1100.  2017-05-09
  30. Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation
    Authors: SS Oh, S Park, KW Lee, H Madhi, SG Park, HG Lee, YY Cho, J Yoo, K Dong Kim
    Cell Death Dis, 2017-04-06;8(4):e2729.  2017-04-06
  31. The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation
    Authors: M McMillin, G Frampton, S Grant, S DeMorrow
    Am. J. Pathol, 2017-02-11;0(0):.  2017-02-11
  32. Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling
    Authors: AK Piper, SE Ross, GM Redpath, FA Lemckert, N Woolger, A Bournazos, PA Greer, RB Sutton, ST Cooper
    Cell. Signal, 2017-02-10;33(0):30-40.  2017-02-10
  33. Use of non-selective ?-blockers is associated with decreased tumor proliferative indices in early stage breast cancer
    Authors: A Montoya, CN Amaya, A Belmont, N Diab, R Trevino, G Villanueva, S Rains, LA Sanchez, N Badri, S Otoukesh, A Khammanivo, D Liss, ST Baca, RJ Aguilera, EB Dickerson, A Torabi, AK Dwivedi, A Abbas, K Chambers, BA Bryan, Z Nahleh
    Oncotarget, 2017-01-24;8(4):6446-6460.  2017-01-24
  34. Native matrix-based human lung alveolar tissue model in vitro: studies of the reparatory actions of mesenchymal stem cells
    Authors: Ieva Bruzauskai
    Cytotechnology, 2016-12-01;0(0):.  2016-12-01
  35. Selective p38? MAP kinase/MAPK14 inhibition in enzymatically-modified LDL-stimulated human monocytes: implications for atherosclerosis
    Authors: Michael Torzewski
    FASEB J., 2016-11-08;0(0):.  2016-11-08
  36. Chondrogenic Differentiation of Mesenchymal Stem Cells in Three-Dimensional Chitosan Film Culture
    Authors: TJ Lu, FY Chiu, HY Chiu, MC Chang, SC Hung
    Cell Transplant, 2016-10-12;26(3):417-427.  2016-10-12
  37. Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists
    Sci Rep, 2016-09-26;6(0):34145.  2016-09-26
  38. KLRC3, a Natural Killer receptor gene, is a key factor involved in glioblastoma tumourigenesis and aggressiveness
    J Cell Mol Med, 2016-09-19;0(0):.  2016-09-19
  39. IL-17A mediates inflammatory and tissue remodelling events in early human tendinopathy
    Authors: Neal L Millar
    Sci Rep, 2016-06-06;6(0):27149.  2016-06-06
  40. Metabolites involved in glycolysis and amino acid metabolism are altered in short children born small for gestational age
    Authors: Peter E Clayton
    Pediatr. Res., 2016-04-08;80(2):299-305.  2016-04-08
  41. Transmembrane TNF-alpha Reverse Signaling Inhibits Lipopolysaccharide-Induced Proinflammatory Cytokine Formation in Macrophages by Inducing TGF-beta: Therapeutic Implications.
    Authors: Pallai A, Kiss B, Vereb G, Armaka M, Kollias G, Szekanecz Z, Szondy Z
    J Immunol, 2016-01-04;196(3):1146-57.  2016-01-04
  42. Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma.
    Authors: Schmithals C, Koberle V, Korkusuz H, Pleli T, Kakoschky B, Augusto E, Ibrahim A, Arencibia J, Vafaizadeh V, Groner B, Korf H, Kronenberger B, Zeuzem S, Vogl T, Waidmann O, Piiper A
    Cancer Res, 2015-08-01;75(15):3147-54.  2015-08-01
  43. MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease.
    Authors: Millar N, Gilchrist D, Akbar M, Reilly J, Kerr S, Campbell A, Murrell G, Liew F, Kurowska-Stolarska M, McInnes I
    Nat Commun, 2015-04-10;6(0):6774.  2015-04-10
  44. A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture.
    Authors: Onuma, Yasuko, Higuchi, Kumiko, Aiki, Yasuhiko, Shu, Yujing, Asada, Masahiro, Asashima, Makoto, Suzuki, Masashi, Imamura, Toru, Ito, Yuzuru
    PLoS ONE, 2015-04-07;10(4):e0118931.  2015-04-07
  45. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.
    Authors: Lourenco S, Teixeira V, Kalber T, Jose R, Floto R, Janes S
    J Immunol, 2015-02-23;194(7):3463-74.  2015-02-23
  46. ADAM8 as a drug target in pancreatic cancer.
    Authors: Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia A, Hofling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem R, Moss M, Rasmussen F, Miller M, Lauffenburger D, Tuveson D, Nimsky C, Bartsch J
    Nat Commun, 2015-01-28;6(0):6175.  2015-01-28
  47. Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection.
    Authors: Royall E, Doyle N, Abdul-Wahab A, Emmott E, Morley S, Goodfellow I, Roberts L, Locker N
    J Biol Chem, 2015-01-05;290(8):4748-58.  2015-01-05
  48. Intracellular carbonic anhydrase activity sensitizes cancer cell pH signaling to dynamic changes in CO2 partial pressure.
    Authors: Hulikova A, Aveyard N, Harris A, Vaughan-Jones R, Swietach P
    J Biol Chem, 2014-07-24;289(37):25418-30.  2014-07-24
  49. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors.
    Authors: Wilson C, Naves T, Vincent F, Melloni B, Bonnaud F, Lalloue F, Jauberteau M
    J Cell Sci, 2014-07-18;127(0):3983-97.  2014-07-18
  50. DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes.
    Authors: Sakaguchi M, Murata H, Aoyama Y, Hibino T, Putranto E, Ruma I, Inoue Y, Sakaguchi Y, Yamamoto K, Kinoshita R, Futami J, Kataoka K, Iwatsuki K, Huh N
    J Biol Chem, 2014-07-07;289(34):23389-402.  2014-07-07
  51. The antiviral immune response in human conventional dendritic cells is controlled by the mammalian target of rapamycin.
    Authors: Fekete T, Pazmandi K, Szabo A, Bacsi A, Koncz G, Rajnavolgyi E
    J Leukoc Biol, 2014-07-07;96(4):579-89.  2014-07-07
  52. TGFbeta activated kinase 1 (TAK1) at the crossroad of B cell receptor and Toll-like receptor 9 signaling pathways in human B cells.
    Authors: Szili D, Banko Z, Toth E, Nagy G, Rojkovich B, Gati T, Simon M, Herincs Z, Sarmay G
    PLoS ONE, 2014-05-06;9(5):e96381.  2014-05-06
  53. Extract of Cordyceps militaris inhibits angiogenesis and suppresses tumor growth of human malignant melanoma cells.
    Authors: Ruma I, Putranto E, Kondo E, Watanabe R, Saito K, Inoue Y, Yamamoto K, Nakata S, Kaihata M, Murata H, Sakaguchi M
    Int J Oncol, 2014-04-24;45(1):209-18.  2014-04-24
  54. Genome-wide study of hypomethylated and induced genes in patients with liver cancer unravels novel anticancer targets.
    Authors: Stefanska B, Cheishvili D, Suderman M, Arakelian A, Huang J, Hallett M, Han Z, Al-Mahtab M, Akbar S, Khan W, Raqib R, Tanvir I, Khan H, Rabbani S, Szyf M
    Clin Cancer Res, 2014-04-24;20(12):3118-32.  2014-04-24
  55. Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3beta pathways in vivo.
    Authors: Fullar A, Baghy K, Deak F, Peterfia B, Zsak Y, Tatrai P, Schaff Z, Dudas J, Kiss I, Kovalszky I
    PLoS ONE, 2014-04-01;9(4):e93469.  2014-04-01
  56. COX-2-independent effects of celecoxib sensitize lymphoma B cells to TRAIL-mediated apoptosis.
    Authors: Gallouet A, Travert M, Bresson-Bepoldin L, Guilloton F, Pangault C, Caulet-Maugendre S, Lamy T, Tarte K, Guillaudeux T
    Clin Cancer Res, 2014-03-17;20(10):2663-73.  2014-03-17
  57. Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis.
    Authors: White N, Masui O, Newsted D, Scorilas A, Romaschin A, Bjarnason G, Siu K, Yousef G
    Br J Cancer, 2014-02-04;110(5):1250-9.  2014-02-04
  58. Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.
    Authors: Labidi-Galy S, Clauss A, Ng V, Duraisamy S, Elias K, Piao H, Bilal E, Davidowitz R, Lu Y, Badalian-Very G, Gyorffy B, Kang U, Ficarro S, Ganesan S, Mills G, Marto J, Drapkin R
    Oncogene, 2014-01-27;34(3):373-83.  2014-01-27
  59. Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability.
    Authors: Gutsaeva, Diana R, Montero-Huerta, Pedro, Parkerson, James B, Yerigenahally, Shobha D, Ikuta, Tohru, Head, C Alvin
    Blood, 2014-01-15;123(12):1917-26.  2014-01-15
  60. The niche component periostin is produced by cancer-associated fibroblasts, supporting growth of gastric cancer through ERK activation.
    Authors: Kikuchi Y, Kunita A, Iwata C, Komura D, Nishiyama T, Shimazu K, Takeshita K, Shibahara J, Kii I, Morishita Y, Yashiro M, Hirakawa K, Miyazono K, Kudo A, Fukayama M, Kashima T
    Am J Pathol, 2014-01-10;184(3):859-70.  2014-01-10
  61. EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy.
    Authors: Skoda J, Neradil J, Zitterbart K, Sterba J, Veselska R
    Oncol Rep, 2013-11-20;31(1):480-7.  2013-11-20
  62. A unifying mechanism for cancer cell death through ion channel activation by HAMLET.
    Authors: Storm P, Klausen T, Trulsson M, Ho C S J, Dosnon M, Westergren T, Chao Y, Rydstrom A, Yang H, Pedersen S, Svanborg C
    PLoS ONE, 2013-03-07;8(3):e58578.  2013-03-07
  63. Sunlight UV-induced skin cancer relies upon activation of the p38alpha signaling pathway.
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Proteome Profiler Human Phospho-MAPK Array Kit
By Anonymous on 05/24/2019

Good screening tool, would be nice if this was available for total levels and other species such as mouse.

Proteome Profiler Human Phospho-MAPK Array Kit
By Anonymous on 01/03/2017

This array is an excellent tool for screening potential phospho-MAPKs and related targets. However, it would be nice that if the total level of non-phosphorylated proteins be visualized at the same time on the membrane. In this case, the phosphorylated signals can be normalized.