Recombinant Human beta-NGF Protein

Carrier Free

Catalog # Availability Size / Price Qty
256-GF-100/CF

With Carrier

Catalog # Availability Size / Price Qty
256-GF-100
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Recombinant Human beta-NGF Protein Bioactivity
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Product Details
Citations (59)
FAQs
Reviews (3)

Recombinant Human beta-NGF Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is 0.2‑2 ng/mL.
Source
Mouse myeloma cell line, NS0-derived human beta-NGF protein
Ser122-Ala241
Accession #
N-terminal Sequence
Analysis
Ser122
Predicted Molecular Mass
13.5 kDa (monomer)
SDS-PAGE
13 kDa, reducing conditions

Product Datasheets

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256-GF (with carrier)

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256-GF/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

256-GF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetic Acid with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

256-GF/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetic Acid.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Recombinant Human beta-NGF Protein Bioactivity View Larger

Recombinant Human beta -NGF (Catalog # 256-GF) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50 for this effect is 0.2‑2 ng/mL.

SDS-PAGE Recombinant Human beta-NGF Protein SDS-PAGE View Larger

1 µg/lane of Recombinant Human beta -NGF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: beta-NGF

NGF was initially isolated in the mouse submandibular gland as a 7S complex composed of three non-covalently linked subunits, alpha, beta, and  gamma. Both the alpha and  gamma subunits of NGF are members of the kallikrein family of serine proteases while the beta  subunit, called beta -NGF or 2.5S NGF, exhibits all the biological activities ascribed to NGF. Recombinant human beta -NGF is a homodimer of two 120 amino acid polypeptides. The human protein shares approximately 90% homology at the amino acid level with both the mouse and rat beta -NGF and exhibits cross-species activity.

NGF is a well-characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF has also been shown to have biological effects on non-neuronal tissues. NGF is mitogenic for a factor‑dependent human erythroleukemic cell line, TF-1. NGF has been found to increase the number of mast cells in neonatal rats and to induce histamine release from peritoneal mast cells. NGF will enhance histamine release and strongly modulate the formation of lipid mediators by basophils in response to various stimuli. NGF will also induce the growth and differentiation of human B lymphocytes as well as suppress apoptosis of murine peritoneal neutrophils. These results, taken together, suggest that NGF is a pleiotropic cytokine which, in addition to its neurotropic activities, may have an important role in the regulation of the immune system.

Long Name
beta Nerve Growth Factor
Entrez Gene IDs
4803 (Human); 18049 (Mouse); 310738 (Rat); 403402 (Canine); 103350089 (Rabbit)
Alternate Names
Beta nerve growth factor precursor; beta-nerve growth factor; betaNGF; beta-NGF; HSAN5; MGC161426; nerve growth factor (beta polypeptide); nerve growth factor, beta subunit; NGFB; NGFBMGC161428

Citations for Recombinant Human beta-NGF Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

59 Citations: Showing 1 - 10
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  1. Saxitoxin potentiates human neuronal cell death induced by Zika virus while sparing neural progenitors and astrocytes
    Authors: Souza, LRQ;Pedrosa, CGDS;Puig-Pijuan, T;da Silva Dos Santos, C;Vitória, G;Delou, JMA;Setti-Perdigão, P;Higa, LM;Tanuri, A;Rehen, SK;Guimarães, MZP;
    Scientific reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Neuro-mesenchymal interaction mediated by a ?2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression
    Authors: Kobayashi, H;Iida, T;Ochiai, Y;Malagola, E;Zhi, X;White, RA;Qian, J;Wu, F;Waterbury, QT;Tu, R;Zheng, B;LaBella, JS;Zamechek, LB;Ogura, A;Woods, SL;Worthley, DL;Enomoto, A;Wang, TC;
    Cancer discovery
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons
    Authors: Held, A;Adler, M;Marques, C;Reyes, CJ;Kavuturu, AS;Quadros, ARAA;Ndayambaje, IS;Lara, E;Ward, M;Lagier-Tourenne, C;Wainger, BJ;
    Cell reports
    Species: Human
    Sample Types: Whole Cell
    Applications: Cell Culture
  4. Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis
    Authors: Bai, Z;Bartelo, N;Aslam, M;Hale, C;Blachere, NE;Parveen, S;Spolaore, E;DiCarlo, E;Gravallese, E;Smith, MH;Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, ;Frank, MO;Jiang, CS;Zhang, H;Lewis, MJ;Sikandar, S;Pitzalis, C;Malfait, AM;Miller, RE;Zhang, F;Goodman, S;Darnell, R;Wang, F;Orange, DE;
    medRxiv : the preprint server for health sciences
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Actin cytoskeletal dynamics do not impose an energy drain on growth cone bioenergetics
    Authors: Holland, SM;Gallo, G;
    Journal of cell science
    Applications: Cell Culture
  6. Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress
    Authors: Onda-Ohto, A;Hasegawa-Ogawa, M;Matsuno, H;Shiraishi, T;Bono, K;Hiraki, H;Kanegae, Y;Iguchi, Y;Okano, HJ;
    Molecular brain
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Regenerative capacity of trophoblast stem cell-derived extracellular vesicles on mesenchymal stem cells
    Authors: Go, YY;Lee, CM;Chae, SW;Song, JJ;
    Biomaterials research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. An LRP1-binding motif in cellular prion protein replicates cell-signaling activities of the full-length protein
    Authors: Mantuano, E;Zampieri, C;Azmoon, P;Gunner, CB;Heye, KR;Gonias, SL;
    JCI insight
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  9. Analysis of ?-nerve growth factor and its precursor during human pregnancy by immunoaffinity-liquid chromatography tandem mass spectrometry
    Authors: Walsh, J;Palandra, J;Goihberg, E;Deng, S;Hurst, S;Neubert, H;
    Scientific reports
    Species: Human
    Sample Types: Serum
  10. IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries
    Authors: Tam, KW;Wong, CY;Wu, KL;Lam, G;Liang, X;Wong, WT;Li, MT;Liu, WY;Cai, S;Shea, GK;Shum, DK;Chan, YS;
    Cells
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Stem cell-nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy
    Authors: YH Lai, CY Su, HW Cheng, CY Chu, LB Jeng, CS Chiang, WC Shyu, SY Chen
    Nature Communications, 2023-01-18;14(1):285.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. The expression of nerve growth factor in healthy and inflamed equine chondrocytes analysed by capillary western immunoassay
    Authors: S Nyström, A Kendall, S Adepu, A Lindahl, E Skiöldebra
    Research in Veterinary Science, 2022-08-22;151(0):156-163.
    Species: Horse
    Sample Types: Cell Lysates
    Applications: Control
  13. Specific Attenuation of Purinergic Signaling during Bortezomib-Induced Peripheral Neuropathy In Vitro
    Authors: AK Holzer, I Suciu, C Karreman, T Goj, M Leist
    International Journal of Molecular Sciences, 2022-03-29;23(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  14. Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice
    Authors: D Segelcke, HK Fischer, M Hütte, S Dennerlein, F Benseler, N Brose, EM Pogatzki-Z, M Schmidt
    Cell Reports, 2021-12-21;37(12):110152.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits
    Authors: P Göttle, K Schichel, L Reiche, L Werner, A Zink, A Prigione, P Küry
    Frontiers in Cellular Neuroscience, 2021-11-23;15(0):777542.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  16. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers
    Authors: AT Regua, NR Aguayo, SA Jalboush, DL Doheny, SG Manore, D Zhu, GL Wong, A Arrigo, CJ Wagner, Y Yu, A Thomas, MD Chan, J Ruiz, G Jin, R Strowd, P Sun, J Lin, HW Lo
    Cancers, 2021-05-12;13(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency
    Authors: B Sun, X Yang, F Hou, X Yu, Q Wang, HS Oh, P Raja, JM Pesola, EAH Vanni, S McCarron, J Morris-Lov, AHM Ng, GM Church, DM Knipe, DM Coen, D Pan
    Nature Microbiology, 2021-02-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro
    Authors: KM Prautsch, A Schmidt, V Paradiso, DJ Schaefer, R Guzman, DF Kalbermatt, S Madduri
    Cells, 2020-08-21;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  19. Mechanical stimulation of Schwann cells promote peripheral nerve regeneration via extracellular vesicle-mediated transfer of microRNA 23b-3p
    Authors: B Xia, J Gao, S Li, L Huang, L Zhu, T Ma, L Zhao, Y Yang, K Luo, X Shi, L Mei, H Zhang, Y Zheng, L Lu, Z Luo, J Huang
    Theranostics, 2020-07-11;10(20):8974-8995.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  20. Establishment of a simple one-step method for oligodendrocyte progenitor cell preparation from rodent brains
    Authors: A Yoshida, K Takashima, T Shimonaga, M Kadokura, S Nagase, S Koda
    J. Neurosci. Methods, 2020-05-30;0(0):108798.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Generation of Multipotent Stem Cells from Adult Human Peripheral Blood Following the Treatment with Platelet-Derived Mitochondria
    Authors: H Yu, W Hu, X Song, Y Zhao
    Cells, 2020-05-29;9(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. An in vivo platform to select and evolve aggregation-resistant proteins
    Authors: JS Ebo, JC Saunders, PWA Devine, AM Gordon, AS Warwick, B Schiffrin, SE Chin, E England, JD Button, C Lloyd, NJ Bond, AE Ashcroft, SE Radford, DC Lowe, DJ Brockwell
    Nat Commun, 2020-04-14;11(1):1816.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  23. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells
    Authors: AR Nickolls, MM Lee, DF Espinoza, M Szczot, RM Lam, Q Wang, J Beers, J Zou, MQ Nguyen, HJ Solinski, AA AlJanahi, KR Johnson, ME Ward, AT Chesler, CG Bönnemann
    Cell Rep, 2020-01-21;30(3):932-946.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  24. Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor
    Authors: N Uesato, N Miyagawa, K Inagaki, R Kakefuda, Y Kitagawa, Y Matsuo, T Yamaguchi, T Hata, K Ikegashira, M Matsushita
    Biol. Pharm. Bull., 2020-01-01;43(2):325-333.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  25. Extracellular Vesicles Derived From Olfactory Ensheathing Cells Promote Peripheral Nerve Regeneration in Rats
    Authors: B Xia, J Gao, S Li, L Huang, T Ma, L Zhao, Y Yang, J Huang, Z Luo
    Front Cell Neurosci, 2019-12-06;13(0):548.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  26. Promotion of Axon Growth by the Secreted End of a Transcription Factor
    Authors: EP McCurdy, KM Chung, CR Benitez-Ag, U Hengst
    Cell Rep, 2019-10-08;29(2):363-377.e5.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  27. No evidence for altered plasma NGF and BDNF levels in fibromyalgia patients
    Authors: D Baumeister, W Eich, S Saft, O Geisel, R Hellweg, A Finn, CI Svensson, J Tesarz
    Sci Rep, 2019-09-20;9(1):13667.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Standard
  28. Differentiation of Motor Neuron-Like Cells from Tonsil-Derived Mesenchymal Stem Cells and Their Possible Application to Neuromuscular Junction Formation
    Authors: S Park, JY Kim, S Myung, N Jung, Y Choi, SC Jung
    Int J Mol Sci, 2019-06-01;20(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis
    Authors: A Kizilyer, MV Singh, VB Singh, S Suwunnakor, J Palis, SB Maggirwar
    Sci Rep, 2019-02-26;9(1):2781.
    Species: Human
    Sample Types:
    Applications: Bioassay
  30. A C-terminal cysteine residue is required for peptide-based inhibition of the NGF/TrkA interaction at nM concentrations: implications for peptide-based analgesics
    Authors: AJ Poole, L Frigotto, ME Smith, C Baar, G Ivanova-Be, A Jaulent, C Stace, CG Ullman, AV Hine
    Sci Rep, 2019-01-30;9(1):930.
    Species: Human
    Sample Types: Peptide, Recombinant Protein
    Applications: ELISA (Capture), ELISA (Standard)
  31. Modeling Diabetic Corneal Neuropathy in a 3D In Vitro Cornea System
    Authors: PM Deardorff, TB McKay, S Wang, CE Ghezzi, DM Cairns, RD Abbott, JL Funderburg, KR Kenyon, DL Kaplan
    Sci Rep, 2018-11-23;8(1):17294.
    Species: Human
    Sample Types: Complex Sample Type
    Applications: Bioassay
  32. Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition
    Authors: K Kirino, T Nakahata, T Taguchi, MK Saito
    Sci Rep, 2018-08-27;8(1):12865.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma
    Authors: JW Martin, JC Chen, J Neidleman, K Tatsumi, J Hu, LC Giudice, WC Greene, NR Roan
    Biol. Reprod., 2018-08-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer
    Authors: DR Gomez, LA Byers, M Nilsson, L Diao, J Wang, L Li, P Tong, M Hofstad, B Saigal, I Wistuba, N Kalhor, S Swisher, Y Fan, WK Hong, M Suraokar, C Behrens, C Moran, JV Heymach
    Oncotarget, 2018-01-30;9(18):14268-14284.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain
    Authors: T Miladinovi, RG Ungard, K Linher-Mel, S Popovic, G Singh
    Mol Pain, 2018-01-01;14(0):1744806918776.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Immunohistochemical and immunocytochemical study of mechanoreceptors in anterior cruciate ligament reconstruction with the remnant-preserving technique using Achilles tendon allografts
    Authors: KC Chun, SH Lee, JW Kim, EJ Jin, KM Kim, CH Chun
    J Orthop Surg Res, 2017-06-14;12(1):93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo
    Sci Rep, 2016-12-20;6(0):38644.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function
    Proc. Natl. Acad. Sci. U.S.A, 2016-12-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Nerve Growth Factor Attenuates Apoptosis and Inflammation in the Diabetic Cornea
    Invest. Ophthalmol. Vis. Sci, 2016-12-01;57(15):6767-6775.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models
    Sci Rep, 2016-09-19;6(0):33427.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury
    Authors: S Delbary-Go, S Lee, M Baroni, I Lamarche, M Arnone, B Canolle, A Lin, J Sacramento, EA Salegio, MN Castel, N Delesque-T, A Alam, P Laboudie, B Ferzaz, P Savi, JM Herbert, GT Manley, AR Ferguson, JC Bresnahan, F Bono, MS Beattie
    Brain, 2016-04-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Isolation, expansion and neural differentiation of stem cells from human plucked hair: a further step towards autologous nerve recovery
    Authors: Margriet A Huisman
    Cytotechnology, 2015-12-24;68(5):1849-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Effects of Reducing Suppressors of Cytokine Signaling-3 (SOCS3) Expression on Dendritic Outgrowth and Demyelination after Spinal Cord Injury.
    Authors: Park K, Lin C, Li K, Lee Y
    PLoS ONE, 2015-09-18;10(9):e0138301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy.
    Authors: Schwab, Andrew J, Ebert, Allison
    PLoS ONE, 2014-07-23;9(7):e103112.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms.
    Authors: Wan C, Liu J, Nie X, Zhao J, Zhou S, Duan Z, Tang C, Liang L, Xu G
    PLoS ONE, 2014-02-24;9(2):e89811.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury.
    Authors: Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, Sieber-Blum M
    Stem Cells Transl Med, 2014-01-17;3(3):334-45.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Neuropeptides released from trigeminal neurons promote the stratification of human corneal epithelial cells.
    Authors: Ko J, Mizuno Y, Ohki C, Chikama T, Sonoda K, Kiuchi Y
    Invest Ophthalmol Vis Sci, 2014-01-07;55(1):125-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation.
    Authors: Bowers P, Neben T, Tomlinson G, Dalton J, Altobell L, Zhang X, Macomber J, Wu B, Toobian R, McConnell A, Verdino P, Chau B, Horlick R, King D
    J Biol Chem, 2013-01-25;288(11):7688-96.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  49. EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells.
    Authors: Delcroix GJ, Curtis KM, Schiller PC, Montero-Menei CN
    Differentiation, 2010-09-01;80(4):213-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Gottingen minipig basal forebrain.
    Authors: Fjord-Larsen L, Kusk P, Tornoe J, Juliusson B, Torp M, Bjarkam CR, Nielsen MS, Handberg A, Sorensen JC, Wahlberg LU
    Mol. Ther., 2010-07-27;18(12):2164-72.
    Species: Porcine, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  51. A multiplex immunoassay for human adipokine profiling.
    Authors: Schipper HS, De Jager W, van Dijk ME, Meerding J, Zelissen PM, Adan RA, Prakken BJ, Kalkhoven E
    Clin. Chem., 2010-06-08;56(0):1320.
    Applications: ELISA (Standard)
  52. Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis.
    Authors: Foveau B, Ancot F, Leroy C, Petrelli A, Reiss K, Vingtdeux V, Giordano S, Fafeur V, Tulasne D
    Mol. Biol. Cell, 2009-03-18;20(9):2495-507.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function.
    Authors: Samah B, Porcheray F, Gras G
    Clin. Exp. Immunol., 2008-01-08;151(3):476-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat.
    Authors: Paredes D, Granholm AC, Bickford PC
    Brain Res., 2007-01-12;1141(0):56-64.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  55. RhoA-kinase coordinates F-actin organization and myosin II activity during semaphorin-3A-induced axon retraction.
    Authors: Gallo G
    J. Cell. Sci., 2006-08-15;119(0):3413-23.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Elicitation of immunity to HIV type 1 Gag is determined by Gag structure.
    Authors: Young KR, Ross TM
    AIDS Res. Hum. Retroviruses, 2006-01-01;22(1):99-108.
    Applications: Western Blot
  57. Nerve growth factor expression by PLG-mediated lipofection.
    Authors: Whittlesey KJ, Shea LD
    Biomaterials, 2005-11-28;27(11):2477-86.
    Applications: Western Blot
  58. Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide.
    Authors: Adams DN, Kao EY, Hypolite CL, Distefano MD, Hu WS, Letourneau PC
    J. Neurobiol., 2005-01-01;62(1):134-47.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Nerve growth factor overexpression and autocrine loop in breast cancer cells.
    Authors: Dolle L, El Yazidi-Belkoura I, Adriaenssens E, Nurcombe V, Hondermarck H
    Oncogene, 2003-08-28;22(36):5592-601.
    Species: Chicken
    Sample Types: N/A, Whole Cells
    Applications: Bioassay, ELISA (Standard)

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Average Rating: 4.7 (Based on 3 Reviews)

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Recombinant Human beta-NGF Protein
By Anonymous on 05/19/2021
Application: Cell migration/motility

Recombinant Human beta-NGF Protein
By Anonymous on 05/20/2017
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human beta-NGF Protein
By Pratima Rawat on 04/21/2017
Application: grow microglia cells in cell culture media.
Reason for Rating: I found R&D growth factors quality much more superior than other sources.