Home / FGF-10 / Recombinant Human FGF-10 Protein

Recombinant Human FGF-10 Protein

Catalog #: 345-FG
103 Citations 1 Review Datasheet / COA / SDS

Carrier Free

Catalog # Availability Size / Price Qty
345-FG-025/CF

With Carrier

Catalog # Availability Size / Price Qty
345-FG-025
345-FG-250
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Recombinant Human FGF-10 Protein Bioactivity
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Product Details
Citations (103)
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Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human FGF-10 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells. Rubin, J.S. et al. (1989) Proc. Natl. Acad. Sci. USA 86:802. The ED50 for this effect is 20-100 ng/mL.
Source
E. coli-derived human FGF-10 protein
Cys37-Ser208 & Gly41-Ser208
Accession #
O15520
N-terminal Sequence
Analysis
Cys37 & Gly41
Predicted Molecular Mass
19.5 kDa
SDS-PAGE
19-22 kDa, reducing conditions

Product Datasheets

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345-FG (with carrier)

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COA
SDS

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345-FG/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

345-FG

Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

345-FG/CF

Formulation Lyophilized from a 0.2 μm filtered solution in MOPS, Na2SO4, EDTA and DTT.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

Bioactivity Recombinant Human FGF-10 Protein Bioactivity View Larger

Recombinant Human FGF-10 (Catalog # 345-FG) stimulates cell proliferation of the 4MBr‑5 rhesus monkey epithelial cell line. The ED50 for this effect is 20-100 ng/mL.

SDS-PAGE Recombinant Human FGF-10 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human FGF-10 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 21 kDa.

Bioactivity View Larger

Adult stem cells isolated from human lung biopsy tissue were embedded in Cultrex UltiMatrix RGF Basement Membrane Extract (BME001-05) and cultured for 20-60 days in lung organoid expansion medium, which includes Recombinant Human FGF-10 (Catalog # 345-FG), Recombinant Human KGF/FGF-7 (251-KG), Recombinant Human Noggin (6057-NG), and Recombinant Human R-Spondin 1 (4645-RS), along with the other reagents listed in the lung organoid expansion medium recipe in the lung organoid culture protocol. Lung organoids were able to differentiate and exhibit markers for various cell types of the lung. Lung organoids were stained with (A) a Rabbit Anti-Human Cytokeratin 5 (KRT5) Monoclonal Antibody (Novus Biologicals, Catalog # NB110-56916; green) and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, (B) a Hamster Anti-Mouse Podoplanin (PDPN) Monoclonal Antibody (Novus Biologicals, Catalog # NB600-1015; green) to visualize alveolar type I cells and a Goat Anti-Human p63/TP73L Polyclonal Antibody (AF1916; red) to visualize basal cells, and (C, D) a Mouse Anti-MUC5AC Monoclonal Antibody (Novus Biologicals, Catalog # NBP2-15196; green) to visualize Goblet cells and a Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (MAB2018; red). All samples were counterstained with DAPI (5748; blue).

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FGF-10

The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal, and epithelial origin. FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22 (1). Mature human FGF-10 is an approximately 20 kDa protein that contains a serine-rich region near its N-terminus (2, 3). It shares 93% and 96% amino acid sequence identity with mouse and rat FGF-10, respectively. FGF-10 is secreted by mesenchymal cells and associates with extracellular FGF-BP (1, 4). It preferentially binds and activates epithelial cell FGF R2 (IIIb) and interacts more weakly with FGF R1 (IIIb) (5). The mitogenic and chemotactic properties of FGF-10 are critical in many tissues during embryogenesis. This includes limb bud initiation (6), palate development (7), branching morphogenesis and directional outgrowth of lung buds (8, 9), formation of the otic vesicle and chochlea (10), adipogenesis (11), and the development of prostate, mammary, lacrimal, and submandibular salivary glands (12 - 15). FGF R2 (IIIb) signaling in these responsive tissues is similarly important during embryogenesis (7, 10, 13 ‑ 15). The expression and function of FGF-10 are negatively regulated by Shh and BMP-4 in the developing lung (8, 9). Overlapping expression patterns and activities with FGF-3, -7,  and -8 suggest at least a partial redundancy in FGF‑10 biology (7, 10, 14, 15). FGF-10 induced signaling through FGF R2 (IIIb) also contributes to the progression of pancreatic cancer (16).

References
  1. Beenken, A. and M. Mohammadi (2009) Nat. Rev. Drug Discov. 8:235.
  2. Igarashi, M. et al. (1998) J. Biol. Chem. 273:13230.
  3. Emoto, H. et al. (1997) J. Biol. Chem. 272:23191.
  4. Beer, H.-D. et al. (2005) Oncogene 24:5269.
  5. Zhang, X. et al. (2006) J. Biol. Chem. 281:15694.
  6. Min, H. et al. (1998) Genes Dev. 12:3156.
  7. Rice, R. et al. (2004) J. Clin. Invest. 113:1692.
  8. Bellusci, S. et al. (1997) Development 124:4867.
  9. Weaver, M. et al. (2000) Development 127:2695.
  10. Pirvola, U. et al. (2000) J. Neurosci. 20:6125.
  11. Sakaue, H. et al. (2002) Genes Dev. 16:908.
  12. Donjacour, A.A. et al. (2003) Dev. Biol. 261:39.
  13. Mailleux, A.A. et al. (2002) Development 129:53.
  14. Makarenkova, H.P. et al. (2000) Development 127:2563.
  15. Jaskoll, T. et al. (2005) BMC Dev. Biol. 5:11.
  16. Nomura, S. et al. (2008) Br. J. Cancer 99:305.
Long Name
Fibroblast Growth Factor 10
Entrez Gene IDs
2255 (Human); 14165 (Mouse); 25443 (Rat)
Alternate Names
FGF10; FGF-10; fibroblast growth factor 10; Keratinocyte growth factor 2; KGF2; KGF-2; produced by fibroblasts of urinary bladder lamina propria

Citations for Recombinant Human FGF-10 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

103 Citations: Showing 1 - 10
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  1. Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung
    Authors: Peak, KE;Rajaguru, P;Khan, A;Gleghorn, JP;Obaid, G;Ferruzzi, J;Varner, VD;
    bioRxiv : the preprint server for biology
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: Bioassay
  2. Optogenetically modified human embryonic stem cell-derived otic neurons establish functional synaptic connection with cochlear nuclei
    Authors: Chen, Y;Mu, W;Wu, Y;Xu, J;Li, X;Hu, H;Wang, S;Wang, D;Hui, B;Wang, L;Dong, Y;Chen, W;
    Journal of tissue engineering
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Reprogramming human urine cells into intestinal organoids with long-term expansion ability and barrier function
    Authors: Zhang, R;Chen, Y;Feng, Z;Cai, B;Cheng, Y;Du, Y;Ou, S;Chen, H;Pan, M;Liu, H;Pei, D;Cao, S;
    Heliyon
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  4. Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth
    Authors: Donahue, KL;Watkoske, HR;Kadiyala, P;Du, W;Brown, K;Scales, MK;Elhossiny, AM;Espinoza, CE;Lasse Opsahl, EL;Griffith, BD;Wen, Y;Sun, L;Velez-Delgado, A;Renollet, NM;Morales, J;Nedzesky, NM;Baliira, RK;Menjivar, RE;Medina-Cabrera, PI;Rao, A;Allen, B;Shi, J;Frankel, TL;Carpenter, ES;Bednar, F;Zhang, Y;Pasca di Magliano, M;
    Cancer discovery
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures
    Authors: Schäfer, TE;Knol, LI;Haas, FV;Hartley, A;Pernickel, SCS;Jády, A;Finkbeiner, MSC;Achberger, J;Arelaki, S;Modic, Ž;Schröer, K;Zhang, W;Schmidt, B;Schuster, P;Haferkamp, S;Doerner, J;Gebauer, F;Ackermann, M;Kvasnicka, HM;Kulkarni, A;Bots, STF;Kemp, V;Hawinkels, LJAC;Poetsch, AR;Hoeben, RC;Ehrhardt, A;Marchini, A;Ungerechts, G;Ball, CR;Engeland, CE;
    EBioMedicine
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. TGF? and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas
    Authors: Nipper, M;Xu, Y;Liu, J;Yin, X;Liu, Z;Ye, Z;Zhang, J;Chen, Y;Wang, P;
    Cells
    Species: Human
    Sample Types: BALF
    Applications: Cell Culture
  7. Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells
    Authors: Li, C;Liu, Z;Anderson, J;Liu, Z;Tang, L;Li, Y;Peng, N;Chen, J;Liu, X;Fu, L;Townes, TM;Rowe, SM;Bedwell, DM;Guimbellot, J;Zhao, R;
    PloS one
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa
    Authors: Yang, Y;McCullough, CG;Seninge, L;Guo, L;Kwon, WJ;Zhang, Y;Li, NY;Gaddam, S;Pan, C;Zhen, H;Torkelson, J;Glass, IA;Birth Defects Research Laboratory, ;Charville, G;Que, J;Stuart, J;Ding, H;Oro, A;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS
    Authors: Chen, HJ;Gardner, EE;Shah, Y;Zhang, K;Thakur, A;Zhang, C;Elemento, O;Varmus, H;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Intraperitoneal paclitaxel is a safe and effective therapeutic strategy for treating mucinous appendiceal adenocarcinoma
    Authors: Ito, I;Yousef, AMG;Chowdhury, S;Dickson, PN;Naini, ZA;White, MG;Fleten, KG;Flatmark, K;Fournier, KF;Fowlkes, NW;Shen, JP;
    Cancer research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
    Authors: Alber, AB;Marquez, HA;Ma, L;Kwong, G;Thapa, BR;Villacorta-Martin, C;Lindstrom-Vautrin, J;Bawa, P;Wang, F;Luo, Y;Ikonomou, L;Shi, W;Kotton, DN;
    Nature communications
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. A distal lung organoid model to study interstitial lung disease, viral infection and human lung development
    Authors: Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW;
    Nature protocols
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  13. A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors
    Authors: A Floerching, JE Klein, MSC Finkbeiner, TE Schäfer, G Fuchs, J Doerner, H Zirngibl, M Ackermann, HM Kvasnicka, KA Chester, D Jäger, CR Ball, G Ungerechts, CE Engeland
    Cell Death & Disease, 2023-02-10;14(2):104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Generation and expansion of transitional lung organoids from human pluripotent stem cells
    Authors: IM Leko, N Schrode, J Torres, M Pezet, TA Thimraj, KG Beaumont, HW Snoeck
    bioRxiv : the preprint server for biology, 2023-02-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
    Authors: J Tian, JH Chen, SX Chao, K Pelka, M Giannakis, J Hess, K Burke, V Jorgji, P Sindurakar, J Braverman, A Mehta, T Oka, M Huang, D Lieb, M Spurrell, JN Allen, TA Abrams, JW Clark, AC Enzinger, PC Enzinger, SJ Klempner, NJ McCleary, JA Meyerhardt, DP Ryan, MB Yurgelun, K Kanter, EE Van Sevent, I Baiev, G Chi, J Jarnagin, WB Bradford, E Wong, AG Michel, IJ Fetter, G Siravegna, AJ Gemma, A Sharpe, S Demehri, R Leary, CD Campbell, O Yilmaz, GA Getz, AR Parikh, N Hacohen, RB Corcoran
    Nature Medicine, 2023-01-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: likely intersectionality with other neurological conditions
    Authors: G Parthasara, MB Pattison, CC Midkiff
    Journal of Neuroinflammation, 2023-01-17;20(1):10.
    Species: Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Targeting TBK1 to overcome resistance to cancer immunotherapy
    Authors: Y Sun, OY Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, EJ Robitschek, TGR Davis, S Kim, A Fu, X Ma, J Gwee, P Tiwari, PP Du, P Sindurakar, J Tian, A Mehta, AM Schneider, K Yizhak, M Sade-Feldm, T LaSalle, T Sharova, H Xie, S Liu, WA Michaud, R Saad-Beret, KB Yates, A Iracheta-V, JKE Spetz, X Qin, KA Sarosiek, G Zhang, JW Kim, MY Su, AM Cicerchia, MQ Rasmussen, SJ Klempner, D Juric, SI Pai, DM Miller, A Giobbie-Hu, JH Chen, K Pelka, DT Frederick, S Stinson, E Ivanova, AR Aref, CP Paweletz, DA Barbie, DR Sen, DE Fisher, RB Corcoran, N Hacohen, PK Sorger, KT Flaherty, GM Boland, RT Manguso, RW Jenkins
    Nature, 2023-01-12;0(0):.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  18. iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage
    Authors: S Raad, A David, M Sagniez, B Paré, Z Orfi, NA Dumont, MA Smith, C Faure
    Disease Models & Mechanisms, 2022-11-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes
    Authors: H Wang, B Keepers, Y Qian, Y Xie, M Colon, J Liu, L Qian
    Cell Stem Cell, 2022-10-06;29(10):1491-1504.e9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants
    Authors: Y Han, L Tan, T Zhou, L Yang, L Carrau, LA Lacko, M Saeed, J Zhu, Z Zhao, BE Nilsson-Pa, FT Lira Neto, C Cahir, AM Giani, JC Chai, Y Li, X Dong, D Moroziewic, NYSCF Glob, D Paull, T Zhang, S Koo, C Tan, R Danziger, Q Ba, L Feng, Z Chen, A Zhong, GJ Wise, JZ Xiang, H Wang, RE Schwartz, BR tenOever, SA Noggle, CM Rice, Q Qi, T Evans, S Chen
    Cell Stem Cell, 2022-10-06;29(10):1475-1490.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis
    Authors: T Jiang, W Hu, S Zhang, C Ren, S Lin, Z Zhou, H Wu, J Yin, L Tan
    Respiratory Research, 2022-10-01;23(1):269.
    Species: Human
    Sample Types: Whole Cell
    Applications: Cell Culture
  22. Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line
    Authors: MC Jaboreck, JL Lühmann, M Mielenz, F Stanke, G Göhring, U Martin, R Olmer, S Merkert
    Stem Cell Research, 2022-09-14;64(0):102918.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Exposure to e-cigarette vapor extract induces vocal fold epithelial injury and triggers intense mucosal remodeling
    Authors: V Lungova, K Wendt, SL Thibeault
    Oncogene, 2022-08-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. In vitro culture at 39��C during hepatic maturation of human ES cells facilitates hepatocyte-like cell functions
    Authors: S Imamura, K Yoshimoto, S Terada, K Takamuro, KI Kamei
    Scientific Reports, 2022-03-25;12(1):5155.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Magnetic bioassembly platforms towards the generation of extracellular vesicles from human salivary gland functional organoids for epithelial repair
    Authors: A Chansaenro, C Adine, S Charoenlap, S Roytrakul, L Sariya, T Osathanon, S Rungarunle, G Urkasemsin, R Chaisupara, S Yodmuang, GR Souza, JN Ferreira
    Bioactive materials, 2022-02-16;18(0):151-163.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
    Authors: AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells
    Cell Stem Cell, 2021-12-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs
    Authors: L Johnson Ch, H Lahlou, C Steinacher, S Assou, Y Messat, J Dudás, A Edge, B Crespo, M Crosier, C Sergi, A Schrott-Fi, A Zine
    International Journal of Molecular Sciences, 2021-10-07;22(19):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
    Authors: K Gkatzis, P Panza, S Peruzzo, DY Stainier
    Elife, 2021-09-29;10(0):.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  29. Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
    Authors: Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, BJ Cox, SS Nunes, MC Nostro
    Cell Stem Cell, 2021-09-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells
    Authors: MO Lee, SG Lee, CR Jung, YS Son, JW Ryu, KB Jung, JH Ahn, JH Oh, HA Lee, JH Lim, J Kim, I Jang, J Choi, J Jung, K Park, B Lee, DS Kim, MY Son, HS Cho
    Nature Communications, 2021-07-23;12(1):4492.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D
    Authors: AL Rodrigues, HY Liu, YW Chen, M Porotto, A Moscona, HW Snoeck
    Nature Protocols, 2021-03-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas
    Authors: H Tomita, K Tanaka, A Hirata, H Okada, H Imai, Y Shirakami, K Ohnishi, S Sugie, H Aoki, Y Hatano, K Noguchi, T Kanayama, A Niwa, N Suzui, T Miyazaki, T Tanaka, H Akiyama, M Shimizu, K Yoshida, A Hara
    Cell Reports, 2021-02-23;34(8):108772.
    Species: Human
    Sample Types: Reference Standard
  33. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss
    Authors: L Cui, J Zheng, Q Zhao, JR Chen, H Liu, G Peng, Y Wu, C Chen, Q He, H Shi, S Yin, RA Friedman, Y Chen, MX Guan
    JCI Insight, 2020-12-03;5(23):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
    Authors: FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, C Villacorta, A Berical, JC Jean, J Le Suer, T Matte, C Simone-Roa, Y Tang, TM Schlaeger, AM Crane, N Matthias, SXL Huang, SH Randell, J Wu, JR Spence, G Carraro, BR Stripp, A Rab, EJ Sorsher, A Horani, SL Brody, BR Davis, DN Kotton
    Cell Stem Cell, 2020-10-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
    Authors: J Huang, AJ Hume, KM Abo, RB Werder, C Villacorta, KD Alysandrat, ML Beermann, C Simone-Roa, J Lindstrom-, J Olejnik, EL Suder, E Bullitt, A Hinds, A Sharma, M Bosmann, R Wang, F Hawkins, EJ Burks, M Saeed, AA Wilson, E Mühlberger, DN Kotton
    Cell Stem Cell, 2020-09-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
    Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
    Res Sq, 2020-09-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice
    Authors: MT Hoffman, SB Kemp, DJ Salas-Esca, Y Zhang, NG Steele, S The, D Long, S Benitz, W Yan, RF Margolskee, F Bednar, M Pasca di M, HJ Wen, HC Crawford
    Cell Mol Gastroenterol Hepatol, 2020-08-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  38. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
    Authors: J Huang, AJ Hume, KM Abo, RB Werder, C Villacorta, KD Alysandrat, ML Beermann, C Simone-Roa, J Olejnik, EL Suder, E Bullitt, A Hinds, A Sharma, M Bosmann, R Wang, F Hawkins, EJ Burks, M Saeed, AA Wilson, E Mühlberger, DN Kotton
    bioRxiv, 2020-08-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
    Authors: N Chanthra, T Abe, M Miyamoto, K Sekiguchi, C Kwon, Y Hanazono, H Uosaki
    Sci Rep, 2020-03-06;10(1):4249.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells
    Authors: R Matsumoto, H Suga, T Aoi, H Bando, H Fukuoka, G Iguchi, S Narumi, T Hasegawa, K Muguruma, W Ogawa, Y Takahashi
    J. Clin. Invest., 2020-02-03;130(2):641-654.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
    Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
    Cell Stem Cell, 2020;27(1):125-136.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
    Authors: W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho
    Stem Cells, 2019-12-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential
    Authors: A Sahabian, M Sgodda, O Naujok, R Dettmer, J Dahlmann, F Manstein, T Cantz, R Zweigerdt, U Martin, R Olmer
    Cells, 2019-12-04;8(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
    Authors: T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim
    Nat Commun, 2019-10-11;10(1):4647.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
    Authors: V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault
    Nat Commun, 2019-09-24;10(1):4161.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium
    Authors: K Suzuki, M Koyanagi-A, K Uehara, N Hinata, M Fujisawa, T Aoi
    Sci Rep, 2019-07-19;9(1):10506.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
    Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
    Cell Rep, 2019-04-16;27(3):708-718.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. FGF signal is not required for hepatoblast differentiation of human iPS cells
    Authors: Y Toba, A Kiso, S Nakamae, F Sakurai, K Takayama, H Mizuguchi
    Sci Rep, 2019-03-06;9(1):3713.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming
    Authors: N Muraoka, K Nara, F Tamura, H Kojima, H Yamakawa, T Sadahiro, K Miyamoto, M Isomi, S Haginiwa, H Tani, S Kurotsu, R Osakabe, S Torii, S Shimizu, H Okano, Y Sugimoto, K Fukuda, M Ieda
    Nat Commun, 2019-02-20;10(1):674.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Generation of lung organoids from human pluripotent stem cells in vitro
    Authors: AJ Miller, BR Dye, D Ferrer-Tor, DR Hill, AW Overeem, LD Shea, JR Spence
    Nat Protoc, 2019-02-01;14(2):518-540.
    Species: Human
    Sample Types: Spheroids
    Applications: Bioassay
  52. Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors
    Authors: H Noguchi, C Miyagi-Shi, Y Nakashima, T Kinjo, N Kobayashi, I Saitoh, M Watanabe, AMJ Shapiro, T Kin
    Mol Ther Methods Clin Dev, 2019-01-29;13(0):243-252.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
    Authors: C Kumtornrut, T Yamauchi, S Koike, S Aiba, K Yamasaki
    J. Dermatol. Sci., 2019-01-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Generation of human antral and fundic gastric organoids from pluripotent stem cells
    Authors: TR Broda, KW McCracken, JM Wells
    Nat Protoc, 2019-01-01;14(1):28-50.
    Species: Human
    Sample Types: Spheroids
    Applications: Bioassay
  55. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
    Authors: MA Scavuzzo, J Chmielowie, D Yang, K Wamble, LS Chaboub, L Duraine, B Tepe, SM Glasgow, BR Arenkiel, C Brou, B Deneen, M Borowiak
    Cell Rep, 2018-12-26;25(13):3811-3827.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells
    Authors: H Chagraoui, MS Kristianse, JP Ruiz, A Serra-Barr, J Richter, E Hall-Ponse, N Gray, D Waithe, K Clark, P Hublitz, E Repapi, G Otto, P Sopp, S Taylor, S Thongjuea, P Vyas, C Porcher
    Nat Commun, 2018-12-18;9(1):5375.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
    Cell Stem Cell, 2018-09-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation
    Authors: JP Ng-Blichfe, A Schrik, RK Kortekaas, JA Noordhoek, IH Heijink, PS Hiemstra, J Stolk, M Königshoff, R Gosens
    EBioMedicine, 2018-09-17;36(0):461-474.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  59. PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery
    Authors: R Cruz-Acuña, M Quirós, S Huang, D Siuda, JR Spence, A Nusrat, AJ García
    Nat Protoc, 2018-09-01;0(0):.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  60. Characteristics and multi?lineage differentiation of bone marrow mesenchymal stem cells derived from the Tibetan mastiff
    Authors: S Zhang, C Zhao, S Liu, Y Wang, Y Zhao, W Guan, Z Zhu
    Mol Med Rep, 2018-06-15;0(0):.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Modeling human early otic sensory cell development with induced pluripotent stem cells
    Authors: H Lahlou, A Lopez-Juar, A Fontbonne, E Nivet, A Zine
    PLoS ONE, 2018-06-14;13(6):e0198954.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
    Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
    Cell Stem Cell, 2018-05-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Beta-Catenin maintains lung epithelial progenitors after lung specification
    Authors: EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen
    Development, 2018-03-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
    Authors: B Memon, M Karam, S Al-Khawaga, EM Abdelalim
    Stem Cell Res Ther, 2018-01-23;9(1):15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Functional vascularized lung grafts for lung bioengineering
    Authors: NV Dorrello, BA Guenthart, JD O'Neill, J Kim, K Cunningham, YW Chen, M Biscotti, T Swayne, HM Wobma, SXL Huang, HW Snoeck, M Bacchetta, G Vunjak-Nov
    Sci Adv, 2017-08-30;3(8):e1700521.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
    Authors: KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro
    Nat Commun, 2017-08-24;8(1):331.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. ?E-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation
    Authors: AJ Jimenez-Ca, R Pillich, W Yang, GR Diaferia, P Meda, L Crisa, V Cirulli
    Cell Rep, 2017-08-08;20(6):1295-1306.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts
    Authors: CR Ball, F Oppel, KR Ehrenberg, TD Dubash, SM Dieter, CM Hoffmann, U Abel, F Herbst, M Koch, J Werner, F Bergmann, N Ishaque, M Schmidt, C von Kalle, C Scholl, S Fröhling, B Brors, W Weichert, J Weitz, H Glimm
    EMBO Mol Med, 2017-07-01;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  69. Ex vivo analysis of the contribution of FGF10(+) cells to airway smooth muscle cell formation during early lung development
    Authors: E El Agha, V Kheirollah, A Moiseenko, W Seeger, S Bellusci
    Dev. Dyn., 2017-06-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
    Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
    Cell Stem Cell, 2017-03-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Transcription factor Etv5 is essential for the maintenance of alveolar type II cells
    Authors: Z Zhang, K Newton, SK Kummerfeld, J Webster, DS Kirkpatric, L Phu, J Eastham-An, J Liu, WP Lee, J Wu, H Li, MR Junttila, VM Dixit
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-28;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  72. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway
    Authors: CE Weeden, Y Chen, SB Ma, Y Hu, G Ramm, KD Sutherland, GK Smyth, ML Asselin-La
    PLoS Biol, 2017-01-26;15(1):e2000731.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis
    Cell Rep, 2016-11-08;17(7):1832-1844.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Binding Assay
  74. TGF-?1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
    Sci Rep, 2016-08-03;6(0):30904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Photodynamic therapy inhibit Fibroblast Growth Factor-10 induced keratinocyte differentiation and proliferation through ROS in Fibroblast Growth Factor Receptor-2b pathway
    Authors: Maya Valeska Gozali
    Sci Rep, 2016-06-07;6(0):27402.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration
    Authors: Yasuhiro Ikeda
    Stem Cells Transl Med, 2016-03-17;5(5):694-702.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Unliganded fibroblast growth factor receptor 1 forms density-independent dimers.
    Authors: Comps-Agrar L, Dunshee D, Eaton D, Sonoda J
    J Biol Chem, 2015-08-13;290(40):24166-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure.
    Authors: Calderon-Gierszal E, Prins G
    PLoS ONE, 2015-07-29;10(7):e0133238.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cells.
    Authors: Maass K, Shekhar A, Lu J, Kang G, See F, Kim E, Delgado C, Shen S, Cohen L, Fishman G
    Stem Cells, 2015-04-01;33(4):1102-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.
    Authors: Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor A, Yasuda Y, Niki T
    BMC Cancer, 2015-02-25;15(0):82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.
    Authors: Wong, Amy P, Chin, Stephani, Xia, Sunny, Garner, Jodi, Bear, Christin, Rossant, Janet
    Nat Protoc, 2015-02-05;10(3):363-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
    Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
    Nat Protoc, 2015-02-05;10(3):413-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Leading and trailing cells cooperate in collective migration of the zebrafish posterior lateral line primordium.
    Authors: Dalle Nogare D, Somers K, Rao S, Matsuda M, Reichman-Fried M, Raz E, Chitnis A
    Development, 2014-07-25;141(16):3188-96.
    Species: Zebrafish
    Sample Types: Whole Organism
    Applications: In Vivo
  84. Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10.
    Authors: Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, Tamada T, Sugiura H, Harigae H, Ichinose M
    Mol Cell Biol, 2014-05-27;34(15):2848-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro.
    Authors: Pethe, Prasad, Nagvenkar, Punam, Bhartiya, Deepa
    BMC Cell Biol, 2014-05-24;15(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.
    Authors: Ohnuma, Kiyoshi, Fujiki, Ayaka, Yanagihara, Kana, Tachikawa, Saoko, Hayashi, Yohei, Ito, Yuzuru, Onuma, Yasuko, Chan, Techuan, Michiue, Tatsuo, Furue, Miho K, Asashima, Makoto
    Sci Rep, 2014-04-11;4(0):4646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture.
    Authors: Takeuchi, Hiroki, Nakatsuji, Norio, Suemori, Hirofumi
    Sci Rep, 2014-03-27;4(0):4488.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
    Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
    Nat Biotechnol, 2013-12-01;32(1):84-91.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  89. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
    Authors: Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann J, Miyazaki S, Miyazaki J, Szot G, Bottino R, Kim S
    Elife, 2013-11-19;2(0):e00940.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.
    Authors: Weedon M, Cebola I, Patch A, Flanagan S, De Franco E, Caswell R, Rodriguez-Segui S, Shaw-Smith C, Cho C, Lango Allen H, Houghton J, Roth C, Chen R, Hussain K, Marsh P, Vallier L, Murray A, Ellard S, Ferrer J, Hattersley A
    Nat Genet, 2013-11-10;46(1):61-4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Generation of multipotent foregut stem cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Fordham, Robert P, Syed, Yasir A, Moignard, Victoria, Berry, Andrew, Bautista, Ruben, Hanley, Neil A, Jensen, Kim B, Vallier, Ludovic
    Stem Cell Reports, 2013-10-10;1(4):293-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.
    Authors: Thatava T, Kudva Y, Edukulla R, Squillace K, De Lamo J, Khan Y, Sakuma T, Ohmine S, Terzic A, Ikeda Y
    Mol Ther, 2012-11-27;21(1):228-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
    Authors: Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S
    Stem Cells Dev, 2012-02-29;21(12):2273-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells.
    Authors: Prabakar K, Dominguez-Bendala J, Molano R, Pileggi A, Villate S, Ricordi C, Inverardi L
    Cell Transplant, 2011-12-21;21(6):1321-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  95. Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals.
    Authors: Patel N, Sharpe PT, Miletich I
    Dev. Biol., 2011-07-23;358(1):156-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer.
    Authors: Tomlinson DC, Knowles MA
    Am. J. Pathol., 2010-10-01;177(5):2379-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
    Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA
    Cell Stem Cell, 2009-04-03;4(4):348-58.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
    Authors: Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, Suzuki H, Aizawa S, Arakaki M, Yuasa K, Oka K, Chai Y, Nonaka K, Fukumoto S
    J. Biol. Chem., 2008-06-17;283(34):23139-49.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  99. Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.
    Authors: Patel VN, Likar KM, Zisman-Rozen S, Cowherd SN, Lassiter KS, Sher I, Yates EA, Turnbull JE, Ron D, Hoffman MP
    J. Biol. Chem., 2008-01-28;283(14):9308-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells.
    Authors: Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, Park KS, Lee HK
    Biochem. Biophys. Res. Commun., 2007-12-04;366(1):129-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.
    Authors: Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, Eftekhari S, Whitelock JM, Elkin M, Vlodavsky I, Hoffman MP
    Development, 2007-10-24;134(23):4177-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis.
    Authors: Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP
    Development, 2005-02-16;132(6):1223-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein.
    Authors: Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R
    Int. J. Dev. Biol., 2003-02-01;47(1):15-29.
    Species: Xenopus
    Sample Types: In Vivo
    Applications: In Vivo

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Recombinant Human FGF-10 Protein
By Anonymous on 12/28/2020
Application: CellProlif
Reason for Rating: For cell maintenance and protein production
Cell Proliferation Recombinant Human FGF-10 Protein 345-FG