Recombinant Human IFN-alpha B2 (alpha 8) Protein

Catalog #: 11115-1
2 Citations Datasheet / COA / SDS

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11115-1

R&D Systems Recombinant Proteins and Enzymes

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All IFN-alpha B2/IFNA8 Proteins and Enzymes

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Citations (2)

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Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human IFN-alpha B2 (alpha 8) Protein Summary

Product Specifications

Product Datasheets

11115-1

Product Datasheet

COA

SDS

11115-1

Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Reconstitution Calculator

Background: IFN-alpha B2/IFNA8

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name

Interferon alpha 8

Entrez Gene IDs

3445 (Human)

Alternate Names

IFNA8; IFN-alpha 8; IFNalpha B2; IFN-alpha B2; IFN-alpha-8; IFN-alphaB; interferon alpha type 201; interferon alpha-8; Interferon alpha-B; interferon alpha-B'; Interferon alpha-B2; interferon, alpha 8; LeIF B

Related Research Areas

Interferons

Citations for Recombinant Human IFN-alpha B2 (alpha 8) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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Melanoma NOS1 expression promotes dysfunctional IFN signaling.
Authors: Liu Q, Tomei S, Ascierto M, De Giorgi V, Bedognetti D, Dai C, Uccellini L, Spivey T, Pos Z, Thomas J, Reinboth J, Murtas D, Zhang Q, Chouchane L, Weiss G, Slingluff C, Lee P, Rosenberg S, Alter H, Yao K, Wang E, Marincola F
J Clin Invest, 2014-04-01;124(5):2147-59.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
Nature, 2012-07-26;487(7408):505-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay