Home / IFN-beta / Recombinant Human IFN-beta 1a (Mammalian) Protein

Recombinant Human IFN-beta 1a (Mammalian) Protein

Catalog #: 11415-1
8 Citations Datasheet / COA / SDS
Newer Version Available: 8499-IF
NEW
A New rh IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
Catalog # Availability Size / Price Qty
11415-1
R&D Systems Recombinant Proteins and Enzymes
1 Image
Product Details
Citations (8)
FAQs
Reviews
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human IFN-beta 1a (Mammalian) Protein Summary

Product Specifications

Accession #
V00534

Product Datasheets

You must select a language.

x

11415-1

Product Datasheet
COA
SDS

11415-1

Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name
Interferon beta
Entrez Gene IDs
3456 (Human); 15977 (Mouse); 24481 (Rat)
Alternate Names
Fibroblast interferon; IFB; IFBIFNB; IFF; IFNB; IFNB1; IFNbeta; IFN-beta; interferon beta; interferon, beta 1, fibroblast; MGC96956

Citations for Recombinant Human IFN-beta 1a (Mammalian) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
Filter your results:

Filter by:

  1. Functional characterization of Alzheimer's disease genetic variants in microglia
    Authors: Yang, X;Wen, J;Yang, H;Jones, IR;Zhu, X;Liu, W;Li, B;Clelland, CD;Luo, W;Wong, MY;Ren, X;Cui, X;Song, M;Liu, H;Chen, C;Eng, N;Ravichandran, M;Sun, Y;Lee, D;Van Buren, E;Jiang, MZ;Chan, CSY;Ye, CJ;Perera, RM;Gan, L;Li, Y;Shen, Y;
    Nature genetics
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Decreased expression of miR-29 family associated with autoimmune myasthenia gravis
    Authors: MA Cron, CA Payet, OM Fayet, S Maillard, F Truffault, E Fadel, J Guihaire, S Berrih-Akn, A Liston, R Le Panse
    J Neuroinflammation, 2020-10-08;17(1):294.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-beta Therapy.
    Authors: Rasouli J, Ciric B, Imitola J, Gonnella P, Hwang D, Mahajan K, Mari E, Safavi F, Leist T, Zhang G, Rostami A
    J Immunol, 2015-04-27;194(11):5085-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. A 20-amino-acid deletion in the neuraminidase stalk and a five-amino-acid deletion in the NS1 protein both contribute to the pathogenicity of H5N1 avian influenza viruses in mallard ducks.
    Authors: Li, Yanfang, Chen, Sujuan, Zhang, Xiaojian, Fu, Qiang, Zhang, Zhiye, Shi, Shaohua, Zhu, Yinbiao, Gu, Min, Peng, Daxin, Liu, Xiufan
    PLoS ONE, 2014-04-17;9(4):e95539.
    Species: Primate
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Dual regulation of osteopontin production by TLR stimulation in dendritic cells.
    Authors: Salvi V, Scutera S, Rossi S, Zucca M, Alessandria M, Greco D, Bosisio D, Sozzani S, Musso T
    J Leukoc Biol, 2013-04-22;94(1):147-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses.
    Authors: Wang, Bei, Xi, Xueyan, Lei, Xiaobo, Zhang, Xiaoyan, Cui, Sheng, Wang, Jianwei, Jin, Qi, Zhao, Zhendong
    PLoS Pathog, 2013-03-21;9(3):e1003231.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  7. Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans.
    Authors: Popugaeva E, Witkowski PT, Schlegel M, Ulrich RG, Auste B, Rang A, Kruger DH, Klempa B
    PLoS ONE, 2012-04-24;7(4):e35587.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  8. Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines.
    Authors: Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K
    Genes Immun., 2009-10-01;10(8):702-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Why is recombinant Human Interferon-beta 1a (Catalog #'s 11415-1 and 11410-2) formulated with acetic acid?

    • Acetic acid was added to prevent aggregation.

View all Proteins and Enzyme FAQs

Reviews for Recombinant Human IFN-beta 1a (Mammalian) Protein

There are currently no reviews for this product. Be the first to review Recombinant Human IFN-beta 1a (Mammalian) Protein and earn rewards!

Have you used Recombinant Human IFN-beta 1a (Mammalian) Protein?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review