Recombinant Human/Mouse/Rat Activin A Protein

A single-cell transcriptome atlas of human euploid and aneuploid blastocysts
Authors: Wang, S;Leng, L;Wang, Q;Gu, Y;Li, J;An, Y;Deng, Q;Xie, P;Cheng, C;Chen, X;Zhou, Q;Lu, J;Chen, F;Liu, L;Yang, H;Wang, J;Xu, X;Hou, Y;Gong, F;Hu, L;Lu, G;Shang, Z;Lin, G;
Nature genetics
Species: Human
Sample Types: Embryo
Applications: Bioassay

Virological characteristics of a SARS-CoV-2-related bat coronavirus, BANAL-20-236
Authors: Fujita, S;Plianchaisuk, A;Deguchi, S;Ito, H;Nao, N;Wang, L;Nasser, H;Tamura, T;Kimura, I;Kashima, Y;Suzuki, R;Suzuki, S;Kida, I;Tsuda, M;Oda, Y;Hashimoto, R;Watanabe, Y;Uriu, K;Yamasoba, D;Guo, Z;Hinay, AA;Kosugi, Y;Chen, L;Pan, L;Kaku, Y;Chu, H;Donati, F;Temmam, S;Eloit, M;Yamamoto, Y;Nagamoto, T;Asakura, H;Nagashima, M;Sadamasu, K;Yoshimura, K;Suzuki, Y;Genotype to Phenotype Japan (G2P-Japan) Consortium, ;Ito, J;Ikeda, T;Tanaka, S;Matsuno, K;Fukuhara, T;Takayama, K;Sato, K;
EBioMedicine
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine Production
Authors: O'Connell, AE;Raveenthiraraj, S;Oliveira, LFS;Adegboye, C;Dasuri, VS;Qi, W;Khetani, RS;Singh, A;Sundaram, N;Lin, J;Nandivada, P;Rincón-Cruz, L;Goldsmith, JD;Thiagarajah, JR;Carlone, DL;Turner, JR;Agrawal, PB;Helmrath, M;Breault, DT;
Cellular and molecular gastroenterology and hepatology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
Authors: Namoto, K;Baader, C;Orsini, V;Landshammer, A;Breuer, E;Dinh, KT;Ungricht, R;Pikiolek, M;Laurent, S;Lu, B;Aebi, A;Schönberger, K;Vangrevelinghe, E;Evrova, O;Sun, T;Annunziato, S;Lachal, J;Redmond, E;Wang, L;Wetzel, K;Capodieci, P;Turner, J;Schutzius, G;Unterreiner, V;Trunzer, M;Buschmann, N;Behnke, D;Machauer, R;Scheufler, C;Parker, CN;Ferro, M;Grevot, A;Beyerbach, A;Lu, WY;Forbes, SJ;Wagner, J;Bouwmeester, T;Liu, J;Sohal, B;Sahambi, S;Greenbaum, LE;Lohmann, F;Hoppe, P;Cong, F;Sailer, AW;Ruffner, H;Glatthar, R;Humar, B;Clavien, PA;Dill, MT;George, E;Maibaum, J;Liberali, P;Tchorz, JS;
Cell stem cell
Species: Human
Sample Types: Organoid
Applications: Bioassay

The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
Authors: Farahani, E;Reinert, LS;Narita, R;Serrero, MC;Skouboe, MK;van der Horst, D;Assil, S;Zhang, B;Iversen, MB;Gutierrez, E;Hazrati, H;Johannsen, M;Olagnier, D;Kunze, R;Denham, M;Mogensen, TH;Lappe, M;Paludan, SR;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes
Authors: Johnson, BB;Cosson, MV;Tsansizi, LI;Holmes, TL;Gilmore, T;Hampton, K;Song, OR;Vo, NTN;Nasir, A;Chabronova, A;Denning, C;Peffers, MJ;Merry, CLR;Whitelock, J;Troeberg, L;Rushworth, SA;Bernardo, AS;Smith, JGW;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling RET-Rearranged Non-Small Cell Lung Cancer (NSCLC): Generation of Lung Progenitor Cells (LPCs) from Patient-Derived Induced Pluripotent Stem Cells (iPSCs)
Authors: Marcoux, P;Hwang, JW;Desterke, C;Imeri, J;Bennaceur-Griscelli, A;Turhan, AG;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Insulin regulates human pancreatic endocrine cell differentiation in vitro
Authors: Cota, P;Caliskan, ÖS;Bastidas-Ponce, A;Jing, C;Jaki, J;Saber, L;Czarnecki, O;Taskin, D;Blöchinger, AK;Kurth, T;Sterr, M;Burtscher, I;Krahmer, N;Lickert, H;Bakhti, M;
Molecular metabolism
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells
Authors: Tao, Y;Li, X;Dong, Q;Kong, L;Petersen, AJ;Yan, Y;Xu, K;Zima, S;Li, Y;Schmidt, DK;Ayala, M;Mathivanan, S;Sousa, AMM;Chang, Q;Zhang, SC;
Nature biotechnology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells
Authors: Chen, Y;Chen, Y;Li, Q;Liu, H;Han, J;Zhang, H;Cheng, L;Lin, G;
Cell reports
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of CTCF loop formation during pancreatic cell differentiation
Authors: Lyu, X;Rowley, MJ;Kulik, MJ;Dalton, S;Corces, VG;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Using extended growth of cattle embryos in culture to gain insights into bovine developmental events on embryonic days 8 to 10
Authors: Isaac, E;Berg, DK;Pfeffer, PL;
Theriogenology
Species: Bovine
Sample Types: Embryo
Applications: IHC

AAV-Mediated Targeting of the Activin A-ACVR1R206H Signaling in Fibrodysplasia Ossificans Progressiva
Authors: Yang, YS;Lin, C;Ma, H;Xie, J;Kaplan, FS;Gao, G;Shim, JH;
Biomolecules
Species: Transgenic Mouse
Sample Types: Transduced Whole Cells
Applications: Bioassay

Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction
Authors: Shimizu, K;Kikuta, J;Ohta, Y;Uchida, Y;Miyamoto, Y;Morimoto, A;Yari, S;Sato, T;Kamakura, T;Oshima, K;Imai, R;Liu, YC;Okuzaki, D;Hara, T;Motooka, D;Emoto, N;Inohara, H;Ishii, M;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease
Authors: Mullari, M;Fossat, N;Skotte, NH;Asenjo-Martinez, A;Humphreys, DT;Bukh, J;Kirkeby, A;Scheel, TKH;Nielsen, ML;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals
Authors: Lázaro, J;Costanzo, M;Sanaki-Matsumiya, M;Girardot, C;Hayashi, M;Hayashi, K;Diecke, S;Hildebrandt, TB;Lazzari, G;Wu, J;Petkov, S;Behr, R;Trivedi, V;Matsuda, M;Ebisuya, M;
Cell stem cell
Species: Human, Bovine, Mouse, Primate - Callithrix jacchus (Common Marmoset)
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
Authors: Alber, AB;Marquez, HA;Ma, L;Kwong, G;Thapa, BR;Villacorta-Martin, C;Lindstrom-Vautrin, J;Bawa, P;Wang, F;Luo, Y;Ikonomou, L;Shi, W;Kotton, DN;
Nature communications
Species: Transgenic Mouse
Sample Types: Organoid
Applications: Bioassay

A distal lung organoid model to study interstitial lung disease, viral infection and human lung development
Authors: Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW;
Nature protocols
Species: Human
Sample Types: Organoid
Applications: Bioassay

Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components
Authors: E Ugur, A de la Port, W Qin, S Bultmann, A Ivanova, M Drukker, M Mann, M Wierer, H Leonhardt
Nucleic Acids Research, 2023-04-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Strength of CAR signaling determines T�cell versus ILC differentiation from pluripotent stem cells
Authors: S Li, CS Wang, A Montel-Hag, HC Chen, S Lopez, O Zhou, K Dai, S Tsai, W Satyadi, C Botero, C Wong, D Casero, GM Crooks, CS Seet
Cell Reports, 2023-03-11;42(3):112241.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
Authors: AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, W Liedtke, CG Nichols, CL Wu, F Guilak
Elife, 2023-02-22;12(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5
Authors: EB Choi, M Vodnala, P Saini, S Anugula, M Zerbato, JJ Ho, J Wang, SJ Ho Sui, J Yoon, M Roels, C Inouye, YW Fong
The Journal of Biological Chemistry, 2023-02-09;0(0):102996.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
Authors: A Landshamme, A Bolondi, H Kretzmer, C Much, R Buschow, A Rose, HJ Wu, SD Mackowiak, B Braendl, P Giesselman, R Tornisiell, KM Parsi, J Huey, T Mielke, D Meierhofer, R Maehr, D Hnisz, F Michor, JL Rinn, A Meissner
Elife, 2023-01-31;12(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
Authors: P Madrigal, S Deng, Y Feng, S Militi, KJ Goh, R Nibhani, R Grandy, A Osnato, D Ortmann, S Brown, S Pauklin
Nature Communications, 2023-01-25;14(1):405.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype
Authors: PP Shah, KC Keough, K Gjoni, GT Santini, RJ Abdill, NM Wickramasi, CE Dundes, A Karnay, A Chen, REA Salomon, PJ Walsh, SC Nguyen, S Whalen, EF Joyce, KM Loh, N Dubois, KS Pollard, R Jain
Genome Biology, 2023-01-23;24(1):16.
Species: Human
Sample Types: Embryoid Bodies
Applications: Bioassay

In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma
Authors: S Taniguchi, T Matsui, K Kimura, S Funaki, Y Miyamoto, Y Uchida, T Sudo, J Kikuta, T Hara, D Motooka, YC Liu, D Okuzaki, E Morii, N Emoto, Y Shintani, M Ishii
Nature Communications, 2023-01-17;14(1):143.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of Reoviral Cytolysis (II): Cellular Stemness
Authors: Bourhill, T;Rohani, L;Kumar, M;Bose, P;Rancourt, D;Johnston, R;
Viruses
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin B and Activin C Have Opposing Effects on Prostate Cancer Progression and Cell Growth
Authors: KL Reader, S John-McHaf, S Zellhuber-, T Jowett, DG Mottershea, HE Cunliffe, EJ Gold
Cancers, 2022-12-27;15(1):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comparative study of differentiating human pluripotent stem cells into vascular smooth muscle cells in hydrogel-based culture methods
Authors: Q Liu, Z Liu, H Gu, Y Ge, X Wu, F Zuo, Q Du, Y Lei, Z Wang, H Lin
Regenerative Therapy, 2022-12-21;22(0):39-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin A Reduces Porcine Granulosa Cells Apoptosis via ERbeta-Dependent ROS Modulation
Authors: F Chen, X Zhu
Veterinary sciences, 2022-12-18;9(12):.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Programming Multicellular Assembly with Synthetic Cell Adhesion Molecules
Authors: AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux, JT Ramirez, WL McKeithan, F Fattahi, OD Klein, DA Fletcher, WA Lim
Nature, 2022-12-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Production of parathyroid-like cells from thyroid stem cells in co-culture environment
Authors: Ö Karabiyik, GD Nozhatzade, A Tuncer, G Torun Köse, E Hacihasano, F Sahin, E Aysan
Medicine, 2022-12-02;101(48):e32009.
Species: Human
Sample Types: Organoids
Applications: Bioassay

PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders
Authors: D Shang, T Lan, Y Wang, X Li, Q Liu, H Dong, B Xu, H Cheng, R Zhou
Cell & bioscience, 2022-12-01;12(1):194.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system
Authors: AB Menéndez, Z Du, TPP van den Bo, A Othman, N Gaio, C Silvestri, W Quirós, H Lin, S Korevaar, A Merino, J Mulder, MJ Hoogduijn
Scientific Reports, 2022-11-30;12(1):20699.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Stem-Cell-Derived beta-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity
Authors: TM Triolo, JQ Matuschek, R Castro-Gut, AH Shilleh, SPM Williams, MS Hansen, K McDaniel, JM Barra, A Michels, HA Russ
Cells, 2022-11-30;11(23):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage
Authors: S Raad, A David, M Sagniez, B Paré, Z Orfi, NA Dumont, MA Smith, C Faure
Disease Models & Mechanisms, 2022-11-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE
Authors: JA Watts, C Grunseich, Y Rodriguez, Y Liu, D Li, JT Burdick, A Bruzel, RJ Crouch, RW Mahley, SH Wilson, VG Cheung
Nucleic Acids Research, 2022-11-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis
Authors: R Lesage, MN Ferrao Bla, R Narcisi, T Welting, GJVM van Osch, L Geris
Bmc Biology, 2022-11-09;20(1):253.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Membrane Attack Complex Mediates Retinal Pigment Epithelium Cell Death in Stargardt Macular Degeneration
Authors: ESY Ng, N Kady, J Hu, A Dave, Z Jiang, J Pei, MB Gorin, A Matynia, RA Radu
Cells, 2022-11-02;11(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery
Authors: YS Yang, JM Kim, J Xie, S Chaugule, C Lin, H Ma, E Hsiao, J Hong, H Chun, EM Shore, FS Kaplan, G Gao, JH Shim
Oncogene, 2022-10-19;13(1):6175.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A
Authors: A Beucher, I Miguel-Esc, D Balboa, MG De Vas, MA Maestro, J Garcia-Hur, A Bernal, R Gonzalez-F, P Vargiu, H Heyn, P Ravassard, S Ortega, J Ferrer
Nature Cell Biology, 2022-10-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants
Authors: Y Han, L Tan, T Zhou, L Yang, L Carrau, LA Lacko, M Saeed, J Zhu, Z Zhao, BE Nilsson-Pa, FT Lira Neto, C Cahir, AM Giani, JC Chai, Y Li, X Dong, D Moroziewic, NYSCF Glob, D Paull, T Zhang, S Koo, C Tan, R Danziger, Q Ba, L Feng, Z Chen, A Zhong, GJ Wise, JZ Xiang, H Wang, RE Schwartz, BR tenOever, SA Noggle, CM Rice, Q Qi, T Evans, S Chen
Cell Stem Cell, 2022-10-06;29(10):1475-1490.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm
Authors: Z Wang, R Fan, A Russo, FM Cernilogar, A Nuber, S Schirge, I Shcherbako, I Dzhilyanov, E Ugur, T Anton, L Richter, H Leonhardt, H Lickert, G Schotta
Nature Communications, 2022-09-19;13(1):5447.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modeling human multi-lineage heart field development with pluripotent stem cells
Authors: D Yang, J Gomez-Garc, S Funakoshi, T Tran, I Fernandes, GD Bader, MA Laflamme, GM Keller
Cell Stem Cell, 2022-09-01;29(9):1382-1401.e8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7
Authors: A Rössig, K Hill, W Nörenberg, S Weidenbach, S Zierler, M Schaefer, T Gudermann, V Chubanov
Cell Calcium, 2022-08-17;106(0):102640.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Regulation of both transcription and RNA turnover contribute to germline specification
Authors: K Tan, MF Wilkinson
Oncogene, 2022-07-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells
Authors: D Ávila-Gonz, W Portillo, CP Barragán-Á, G Hernandez-, E Flores-Gar, A Molina-Her, NE Díaz-Martí, NF Díaz
Elife, 2022-07-11;11(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation
Authors: S Pulcrano, R De Gregori, C De Sanctis, L Lahti, C Perrone-Ca, D Ponti, U di Porzio, T Perlmann, M Caiazzo, F Volpicelli, GC Bellenchi
International Journal of Molecular Sciences, 2022-06-23;23(13):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Species-Specific Enhancer Activity of OCT4 in Porcine Pluripotency: The Porcine OCT4 Reporter System Could Monitor Pluripotency in Porcine Embryo Development and Embryonic Stem Cells
Authors: SH Kim, M Lee, KH Choi, J Jeong, DK Lee, JN Oh, GC Choe, CK Lee
Stem Cells International, 2022-06-11;2022(0):6337532.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting
Authors: Y Tsujisaka, T Hatani, C Okubo, R Ito, A Kimura, M Narita, K Chonabayas, S Funakoshi, A Lucena-Cac, T Toyoda, K Osafune, T Kimura, H Saito, Y Yoshida
Stem Cell Reports, 2022-06-09;0(0):.
Species: Human
Sample Types: Embryoid Bodies
Applications: Bioassay

Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate
Authors: WS Fagg, N Liu, U Braunschwe, KL Pereira de, X Chen, FS Ditmars, SG Widen, JP Donohue, K Modis, WK Russell, JH Fair, MT Weirauch, BJ Blencowe, MA Garcia-Bla
Nucleic Acids Research, 2022-05-20;50(9):5313-5334.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic Visualization of TGF-beta/SMAD3 Transcriptional Responses in Single Living Cells
Authors: DL Marvin, L You, L Bornes, M van Dinthe, N Peters, H Dang, SK Hakuno, M Hornsveld, O Kranenburg, J van Rheene, JHT Rohling, MP Chien, P Ten Dijke, L Ritsma
Cancers, 2022-05-19;14(10):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chemosynthetic ethanolamine plasmalogen stimulates gonadotropin secretion from bovine gonadotrophs by acting as a potential GPR61 agonist
Authors: H Kadokawa, R Yoshino, R Saito, T Hirokawa
Animal reproduction science, 2022-05-13;241(0):106992.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
Authors: MK Samanta, S Gayen, C Harris, E Maclary, Y Murata-Nak, RM Malcore, RS Porter, PM Garay, CN Vallianato, PB Samollow, S Iwase, S Kalantry
Nature Communications, 2022-05-11;13(1):2602.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Preventing erosion of X-chromosome inactivation in human embryonic stem cells
Authors: M Cloutier, S Kumar, E Buttigieg, L Keller, B Lee, A Williams, S Mojica-Per, I Erliandri, AMD Rocha, K Cadigan, GD Smith, S Kalantry
Nature Communications, 2022-05-06;13(1):2516.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells
Authors: SA Luff, JP Creamer, S Valsoni, C Dege, R Scarfò, A Dacunto, S Cascione, LN Randolph, E Cavalca, I Merelli, SA Morris, A Ditadi, CM Sturgeon
Nature Cell Biology, 2022-04-28;0(0):.
Species: Human
Sample Types: Spheroid
Applications: Bioassay

Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians
Authors: AK Nair, M Traurig, JR Sutherland, YL Muller, ED Grellinger, L Saporito, RG Nelson, C Bogardus, LJ Baier
Cells, 2022-04-25;11(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mapping human haematopoietic stem cells from haemogenic endothelium to birth
Authors: V Calvanese, S Capellera-, F Ma, I Fares, S Liebscher, ES Ng, S Ekstrand, J Aguadé-Gor, A Vavilina, D Lefaudeux, B Nadel, JY Li, Y Wang, LK Lee, R Ardehali, ML Iruela-Ari, M Pellegrini, EG Stanley, AG Elefanty, K Schenke-La, HKA Mikkola
Nature, 2022-04-13;604(7906):534-540.
Species: Human
Sample Types: Transduced Whole Cells
Applications: Bioassay

Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes
Authors: H Kojima, H Yagi, H Kushige, Y Toda, K Takayama, S Masuda, T Morisaku, T Tsuchida, K Kuroda, K Hirukawa, J Inui, K Nishi, Y Nakano, M Tanaka, S Hori, Y Hasegawa, Y Abe, M Kitago, S Adachi, M Tomi, K Matsuura, H Mizuguchi, Y Kitagawa
Cells, 2022-04-07;11(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors
Authors: BK Gage, S Merlin, C Olgasi, A Follenzi, GM Keller
Cell Reports, 2022-04-05;39(1):110621.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cell type determination for cardiac differentiation occurs soon after seeding of human-induced pluripotent stem cells
Authors: CL Jiang, Y Goyal, N Jain, Q Wang, RE Truitt, AJ Coté, B Emert, IA Mellis, K Kiani, W Yang, R Jain, A Raj
Genome Biology, 2022-04-05;23(1):90.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
Authors: S Kim, S Min, YS Choi, SH Jo, JH Jung, K Han, J Kim, S An, YW Ji, YG Kim, SW Cho
Nature Communications, 2022-03-30;13(1):1692.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The effect of docetaxel on retinal pigment epithelial cells
Authors: J Li, X Liu, Q Yang, J Huang, W Zhou, Z Tan, Z Li, D Zhou
Toxicology reports, 2022-03-22;9(0):670-678.
Species: Human
Sample Types: Spheroid
Applications: Bioassay

Orally-active, clinically-translatable senolytics restore alpha-Klotho in mice and humans
Authors: Y Zhu, LGPL Prata, EOW Gerdes, JME Netto, T Pirtskhala, N Giorgadze, U Tripathi, CL Inman, KO Johnson, A Xue, AK Palmer, T Chen, K Schaefer, JN Justice, AM Nambiar, N Musi, SB Kritchevsk, J Chen, S Khosla, D Jurk, MJ Schafer, T Tchkonia, JL Kirkland
EBioMedicine, 2022-03-13;0(0):103912.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T�cells
Authors: Z Wang, HP McWilliams, H Reza, JR Ostberg, W Chen, X Wang, C Huynh, V Vyas, WC Chang, R Starr, JR Wagner, B Aguilar, X Yang, X Wu, J Wang, W Chen, E Koelker-Wo, CS Seet, A Montel-Hag, GM Crooks, SJ Forman, CE Brown
Cell Stem Cell, 2022-03-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ultraefficient extracellular vesicle-guided direct reprogramming of fibroblasts into functional cardiomyocytes
Authors: H Kim, BW Song, SJ Park, SW Choi, H Moon, KC Hwang, SW Kang, SH Moon, Y Yang, IC Kwon, SH Kim
Science Advances, 2022-02-25;8(8):eabj6621.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suspension culture promotes serosal mesothelial development in human intestinal organoids
Authors: MM Capeling, S Huang, CJ Childs, JH Wu, YH Tsai, A Wu, N Garg, EM Holloway, N Sundaram, C Bouffi, M Helmrath, JR Spence
Cell Reports, 2022-02-15;38(7):110379.
Species: Human
Sample Types: Organoids
Applications: Bioassay

Development of Surgically Transplantable Parathyroid Hormone-Releasing Microbeads
Authors: HY Kim, JM Seok, SY Jung, MJ Lee, AN Tran, SJ Yeo, SA Park, HS Kim
Biomedicines, 2022-02-14;10(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Authors: XJ Li, C Morgan, LA Goff, A Doetzlhofe
Science Advances, 2022-02-11;8(6):eabj7651.
Species: Mouse
Sample Types: Organoids
Applications: Bioassay

Leveraging interacting signaling pathways to robustly improve the quality and yield of human pluripotent stem cell-derived hepatoblasts and hepatocytes
Authors: C Raggi, MA M'Callum, QT Pham, P Gaub, S Selleri, NV Baratang, CL Mangahas, G Cagnone, B Reversade, JS Joyal, M Paganelli
Stem Cell Reports, 2022-02-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kinase inhibitor-induced cardiotoxicity assessed in vitro with human pluripotent stem cell derived cardiomyocytes
Authors: HQ Xian, C Blanco, K Bonham, HR Snodgrass
Toxicology and Applied Pharmacology, 2022-01-15;437(0):115886.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats
Authors: T Tada, H Ohnishi, N Yamamoto, F Kuwata, Y Hayashi, H Okuyama, T Morino, Y Kasai, H Kojima, K Omori
Regenerative Therapy, 2022-01-14;19(0):77-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Density-Dependent Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Parathyroid-Hormone-Releasing Cells
Authors: JY Kim, S Park, SY Oh, YH Nam, YM Choi, Y Choi, HY Kim, SY Jung, HS Kim, I Jo, SC Jung
International Journal of Molecular Sciences, 2022-01-10;23(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Offspring production of haploid spermatid-like cells derived from mouse female germline stem cells with chromatin condensation
Authors: X Hu, H Wang, GG Tian, C Hou, B Xu, X Zhao, Y Zhao, Q Fang, X Li, L He, X Chen, S Li, J Wu
Cell & bioscience, 2022-01-04;12(1):5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells
Authors: K Zhao, Y Shi, J Yu, L Yu, A Mael, Y Li, A Kolton, T Joyce, J Odorico, PO Berggren, SN Yang
Cell Transplantation, 2022-01-01;31(0):9636897211066.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Programming Multicellular Assembly with Synthetic Cell Adhesion Molecules
Authors: AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux, JT Ramirez, WL McKeithan, F Fattahi, OD Klein, DA Fletcher, WA Lim
Nature, 2022;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TGFBR3L is an inhibin B co-receptor that regulates female fertility
Authors: E Brûlé, Y Wang, Y Li, YF Lin, X Zhou, L Ongaro, CAI Alonso, ERS Buddle, AL Schneyer, CH Byeon, CS Hinck, N Mendelev, JP Russell, M Cowan, U Boehm, F Ruf-Zamojs, M Zamojski, CL Andoniadou, SC Sealfon, CA Harrison, KL Walton, AP Hinck, DJ Bernard
Science Advances, 2021-12-15;7(51):eabl4391.
Species: Hamster
Sample Types: Whole Cells
Applications: Bioassay

Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model
Authors: R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, D Bose, R Dejene, G Liang, Q Wan, J Chang, BS Jha, O Memon, KJ Miyagishim, A Rising, M Lal, E Hanson, R King, MM Campos, M Ferrer, J Amaral, D McGaughey, K Bharti
Nature Communications, 2021-12-15;12(1):7293.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
Authors: V Chesnokova, S Zonis, A Apostolou, HQ Estrada, S Knott, K Wawrowsky, K Michelsen, A Ben-Shlomo, R Barrett, V Gorbunova, K Karalis, S Melmed
Cell Reports, 2021-12-14;37(11):110068.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
Authors: Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, O Elemento, S Chen, D Huangfu, T Evans
Cell Reports, 2021-12-07;37(10):110095.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids
Authors: S Xia, Z Bozóky, M Di Paola, O Laselva, S Ahmadi, JX Jiang, AL Pitstick, C Jiang, D Rotin, CN Mayhew, NL Jones, CE Bear
Cells, 2021-12-04;10(12):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
Authors: F Xu, C Deng, Z Ren, L Sun, Y Meng, W Liu, J Wan, G Chen
Cell Reports, 2021-11-30;37(9):110063.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
Authors: R Ungricht, L Guibbal, MC Lasbennes, V Orsini, M Beibel, A Waldt, R Cuttat, W Carbone, A Basler, G Roma, F Nigsch, JS Tchorz, D Hoepfner, PS Hoppe
Cell Stem Cell, 2021-11-29;0(0):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors
Authors: RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandrat, DA Roberts, J Wang, S Kefalopoul, A Ramirez, Y Qiu, J Chiou, KJ Gaulton, B Ren, DN Kotton, M Sander
Nature Communications, 2021-11-17;12(1):6636.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo
Authors: JOR Hernandez, X Wang, M Vazquez-Se, M Lopez-Marf, MF Sobral-Rey, A Moran-Horo, M Sundberg, DO Lopez-Cant, CK Probst, GU Ruiz-Espar, K Giannikou, R Abdi, EP Henske, DJ Kwiatkowsk, M Sahin, DR Lemos
Nature Communications, 2021-11-11;12(1):6496.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients
Authors: AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles
Cells, 2021-11-10;10(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modulating mesendoderm competence during human germ layer differentiation
Authors: JR Valcourt, RE Huang, S Kundu, D Venkatasub, RE Kingston, S Ramanathan
Cell Reports, 2021-11-09;37(6):109990.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells
Authors: C Gil-Recio, S Montori, S Al Demour, MA Ababneh, E Ferrés-Pad, C Marti, E Ferrés-Ama, M Barajas, A Al Madhoun, M Atari
Stem Cells International, 2021-11-08;2021(0):5212852.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals
Authors: C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunanda, DM Gonzalez, R Dariolli, SL D'Souza, AS Yadaw, J Hansen, G Jayaraman, B Mathew, M Machado, SI Berger, J Tripodig, V Najfeld, J Garg, M Miller, CS Surlyn, KC Michelis, NC Tangirala, H Weerahandi, DC Thomas, KG Beaumont, R Sebra, M Mahajan, E Schadt, D Vidovic, SC Schürer, J Goldfarb, EU Azeloglu, MR Birtwistle, EA Sobie, JC Kovacic, NC Dubois, R Iyengar
Stem Cell Reports, 2021-11-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Auto/paracrine factors and early Wnt inhibition promote cardiomyocyte differentiation from human induced pluripotent stem cells at initial low cell density
Authors: MNT Le, M Takahi, K Ohnuma
Scientific Reports, 2021-11-02;11(1):21426.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of gammadeltaT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells
Authors: N Hosaka, S Kanda, T Shimono, T Nishiyama
Journal of Cellular and Molecular Medicine, 2021-10-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

An airway organoid-based screen identifies a role for the HIF1alpha-glycolysis axis in SARS-CoV-2 infection
Authors: X Duan, X Tang, MS Nair, T Zhang, Y Qiu, W Zhang, P Wang, Y Huang, J Xiang, H Wang, RE Schwartz, DD Ho, T Evans, S Chen
Cell Reports, 2021-10-15;37(6):109920.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells
Authors: J Lim, E Sakai, F Sakurai, H Mizuguchi
Scientific Reports, 2021-10-06;11(1):19820.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
Authors: Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, BJ Cox, SS Nunes, MC Nostro
Cell Stem Cell, 2021-09-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Derivation of Mouse Parthenogenetic Advanced Stem Cells
Authors: M Wei, J Zhang, J Liu, C Zhao, S Cao, X Yan, B Wu, S Bao
International Journal of Molecular Sciences, 2021-08-20;22(16):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
Authors: AV Parent, G Faleo, J Chavez, M Saxton, DI Berrios, NR Kerper, Q Tang, M Hebrok
Cell Reports, 2021-08-17;36(7):109538.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Improving In Vitro Culture of Human Male Fetal Germ Cells
Authors: M Martin-Ina, M Ferreira, J Taelman, C Eguizabal, SM Chuva De S
Cells, 2021-08-09;10(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes
Authors: T Grancharov, KA Gerbin, AB Rosenberg, CM Roco, JE Arakaki, CM DeLizo, SQ Dinh, RM Donovan-Ma, M Hirano, AM Nelson, J Tang, JA Theriot, C Yan, V Menon, SP Palecek, G Seelig, RN Gunawardan
Scientific Reports, 2021-08-04;11(1):15845.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of insulin-producing pancreatic beta cells from multiple human stem cell lines
Authors: NJ Hogrebe, KG Maxwell, P Augsornwor, JR Millman
Nature Protocols, 2021-08-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells
Authors: MO Lee, SG Lee, CR Jung, YS Son, JW Ryu, KB Jung, JH Ahn, JH Oh, HA Lee, JH Lim, J Kim, I Jang, J Choi, J Jung, K Park, B Lee, DS Kim, MY Son, HS Cho
Nature Communications, 2021-07-23;12(1):4492.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes
Authors: K Sattler, I El-Battraw, L Cyganek, S Lang, H Lan, X Li, Z Zhao, J Utikal, T Wieland, M Borggrefe, X Zhou, I Akin
Scientific Reports, 2021-07-19;11(1):14689.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models
Authors: EJ Grow, BD Weaver, CM Smith, J Guo, P Stein, SC Shadle, PG Hendrickso, NE Johnson, RJ Butterfiel, R Menafra, SL Kloet, SM van der Ma, CJ Williams, BR Cairns
Nature Genetics, 2021-07-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cardiac fibrosis models using human induced pluripotent stem cell-derived cardiac tissues allow anti-fibrotic drug screening in vitro
Authors: H Iseoka, S Miyagawa, Y Sakai, Y Sawa
Stem Cell Research, 2021-06-11;54(0):102420.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The development of a functional human small intestinal epithelium model for drug absorption
Authors: O Kwon, KB Jung, KR Lee, YS Son, H Lee, JJ Kim, K Kim, S Lee, YK Song, J Jung, K Park, DS Kim, MJ Son, MO Lee, TS Han, HS Cho, SJ Oh, H Chung, SH Kim, KS Chung, J Kim, CR Jung, MY Son
Science Advances, 2021-06-02;7(23):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
Authors: S Funakoshi, I Fernandes, O Mastikhina, D Wilkinson, T Tran, W Dhahri, A Mazine, D Yang, B Burnett, J Lee, S Protze, GD Bader, SS Nunes, M Laflamme, G Keller
Nature Communications, 2021-05-26;12(1):3155.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Simplification of culture conditions and feeder-free expansion of bovine embryonic stem cells
Authors: DA Soto, M Navarro, C Zheng, MM Halstead, C Zhou, C Guiltinan, J Wu, PJ Ross
Scientific Reports, 2021-05-26;11(1):11045.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes
Authors: E Zahmatkesh, MH Ghanian, I Zarkesh, Z Farzaneh, M Halvaei, Z Heydari, F Moeinvazir, A Othman, M Ruo beta, A Piryaei, R Gramignoli, S Yakhkeshi, A Nüssler, M Najimi, H Baharvand, M Vosough
Cells, 2021-05-21;10(6):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Sex-Specific Isolation and Propagation of Human Premeiotic Fetal Germ Cells and Germ Cell-Like Cells
Authors: S Mishra, J Taelman, YW Chang, A Boel, P De Sutter, B Heindryckx, SM Chuva De S
Cells, 2021-05-16;10(5):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Single nucleus multi-omics regulatory landscape of the murine pituitary
Authors: F Ruf-Zamojs, Z Zhang, M Zamojski, GR Smith, N Mendelev, H Liu, G Nudelman, M Moriwaki, H Pincas, RG Castanon, VD Nair, N Seenarine, MAS Amper, X Zhou, L Ongaro, C Toufaily, G Schang, JR Nery, A Bartlett, A Aldridge, N Jain, GV Childs, OG Troyanskay, JR Ecker, JL Turgeon, CK Welt, DJ Bernard, SC Sealfon
Nature Communications, 2021-05-11;12(1):2677.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1
Authors: M Huang, Z Liao, X Li, Z Yang, X Fan, Y Li, Z Zhao, S Lang, L Cyganek, X Zhou, I Akin, M Borggrefe, I El-Battraw
Frontiers in Pharmacology, 2021-05-07;12(0):675003.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of candidate PAX2-regulated genes implicated in human kidney development
Authors: Y Yamamura, K Furuichi, Y Murakawa, S Hirabayash, M Yoshihara, K Sako, S Kitajima, T Toyama, Y Iwata, N Sakai, K Hosomichi, PM Murphy, A Tajima, K Okita, K Osafune, S Kaneko, T Wada
Scientific Reports, 2021-04-27;11(1):9123.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role of stromal activin A in human pancreatic cancer and metastasis in mice
Authors: G Mancinelli, C Torres, N Krett, J Bauer, K Castellano, R McKinney, D Dawson, G Guzman, R Hwang, S Grimaldo, P Grippo, B Jung
Scientific Reports, 2021-04-12;11(1):7986.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Capturing human trophoblast development with naive pluripotent stem cells in�vitro
Authors: S Io, M Kabata, Y Iemura, K Semi, N Morone, A Minagawa, B Wang, I Okamoto, T Nakamura, Y Kojima, C Iwatani, H Tsuchiya, B Kaswandy, E Kondoh, S Kaneko, K Woltjen, M Saitou, T Yamamoto, M Mandai, Y Takashima
Cell Stem Cell, 2021-04-07;28(6):1023-1039.e13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK
Authors: CS Lee, HJ Cho, JW Lee, H Son, J Chai, HS Kim
Stem Cell Reports, 2021-04-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in�vitro
Authors: M Chiara Per, N Bellitto, ERS Maylem, F Caloni, LJ Spicer
Theriogenology, 2021-03-28;168(0):1-12.
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

Heterozygous APC germline mutations impart predisposition to colorectal cancer
Authors: L Preisler, A Habib, G Shapira, L Kuznitsov-, Y Mayshar, I Carmel-Gro, M Malcov, F Azem, N Shomron, R Kariv, D Hershkovit, D Ben-Yosef
Scientific Reports, 2021-03-04;11(1):5113.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D
Authors: AL Rodrigues, HY Liu, YW Chen, M Porotto, A Moscona, HW Snoeck
Nature Protocols, 2021-03-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reduced gonadotroph stimulation by ethanolamine plasmalogens in old bovine brains
Authors: H Kadokawa, M Kotaniguch, O Kereilwe, S Kitamura
Scientific Reports, 2021-02-26;11(1):4757.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

Retinoic acid regulates erythropoietin production cooperatively with hypoxia-inducible factors in human iPSC-derived erythropoietin-producing cells
Authors: N Katagiri, H Hitomi, SI Mae, M Kotaka, L Lei, T Yamamoto, A Nishiyama, K Osafune
Scientific Reports, 2021-02-16;11(1):3936.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
Authors: A Mischler, V Karakis, J Mahinthaku, CK Carberry, A San Miguel, JE Rager, RC Fry, BM Rao
The Journal of Biological Chemistry, 2021-02-05;0(0):100386.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
Authors: PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, R Linares-Sa, JG Heffler, N Sayed, D Thomas, Q Wang, LJ Stanton, K Bedi, MP Morley, TP Cappola, AT Owens, KB Margulies, DB Frank, JC Wu, DJ Rader, W Yang, BL Prosser, K Musunuru, R Jain
Cell Stem Cell, 2021-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors
Authors: Q Yan, Y Zhang, X Fang, B Liu, TL Wong, L Gong, S Liu, D Yu, M Liu, L Jiang, X Wang, T Wei, Y Jia, L Li, L Sun, Y Tang, N Zhou, YF Yuan, Y Li, S Ma, XY Guan
Cell Death and Differentiation, 2021-01-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
Authors: CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak
Nature Communications, 2021-01-13;12(1):362.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids
Authors: M Souidi, Y Sleiman, I Acimovic, J Pribyl, A Charrabi, V Baecker, V Scheuerman, M Pesl, S Jelinkova, P Skladal, P Dvorak, A Lacampagne, V Rotrekl, AC Meli
International Journal of Molecular Sciences, 2021-01-11;22(2):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors
Authors: LTG Harland, CS Simon, AD Senft, I Costello, L Greder, I Imaz-Rossh, B Göttgens, JC Marioni, EK Bikoff, C Porcher, MFTR de Bruijn, EJ Robertson
Nature Cell Biology, 2021-01-08;23(1):61-74.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells
Authors: H Fang, S Geng, M Hao, Q Chen, M Liu, C Liu, Z Tian, C Wang, T Takebe, JL Guan, Y Chen, Z Guo, W He, J Diao
Nature Communications, 2021-01-04;12(1):109.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling
Authors: K Uchimura, H Wu, Y Yoshimura, BD Humphreys
Cell Reports, 2020-12-15;33(11):108514.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A microfluidics-based stem cell model of early post-implantation human development
Authors: Y Zheng, Y Shao, J Fu
Nature Protocols, 2020-12-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of a human induced pluripotent stem cell line (iPSC) from peripheral blood mononuclear cells of a patient with a myasthenic syndrome due to mutation in COLQ
Authors: S Barbeau, R Desprat, B Eymard, C Martinat, JM Lemaitre, C Legay
Stem Cell Research, 2020-12-02;49(0):102106.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs
Authors: F Michielin, GG Giobbe, C Luni, Q Hu, I Maroni, MR Orford, A Manfredi, L Di Filippo, AL David, D Cacchiarel, P De Coppi, S Eaton, N Elvassore
Cell Rep, 2020-12-01;33(9):108453.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antagonistic effects of activin A and TNF-&alpha on the activation of L929 fibroblast cells via Smad3-independent signaling
Authors: L Jiang, B Liu, Y Qi, L Zhu, X Cui, Z Liu
Sci Rep, 2020-11-26;10(1):20623.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Authors: CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yi?it, IM Glück, C Trummer, W Qin, MD Bartoschek, FR Traube, E Parsa, E Ugur, M Modic, A Acharya, P Stolz, C Ziegenhain, M Wierer, W Enard, T Carell, DC Lamb, H Takeda, M Nakanishi, S Bultmann, H Leonhardt
Nature Communications, 2020-11-24;11(1):5972.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Authors: RM Samuel, H Majd, MN Richter, Z Ghazizadeh, SM Zekavat, A Navickas, JT Ramirez, H Asgharian, CR Simoneau, LR Bonser, KD Koh, M Garcia-Kni, M Tassetto, S Sunshine, S Farahvashi, A Kalantari, W Liu, R Andino, H Zhao, P Natarajan, DJ Erle, M Ott, H Goodarzi, F Fattahi
Cell Stem Cell, 2020-11-17;27(6):876-889.e12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy
Authors: M Gartz, CW Lin, MA Sussman, MW Lawlor, JL Strande
Dis Model Mech, 2020-11-13;13(11):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
Authors: YS Hwang, S Suzuki, Y Seita, J Ito, Y Sakata, H Aso, K Sato, BP Hermann, K Sasaki
Nat Commun, 2020-11-09;11(1):5656.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into &beta-Like Cells and the Identification of Key miRNAs for Differentiation
Authors: P Mandal, D De, DU Im, SH Um, KK Kim
Biomedicines, 2020-11-09;8(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass
Authors: A Hagg, S Kharoud, G Goodchild, CA Goodman, JL Chen, RE Thomson, H Qian, P Gregorevic, CA Harrison, KL Walton
Front Physiol, 2020-11-04;11(0):560225.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells
Authors: H Fukushima, M Yoshioka, M Kawatou, V López-Dávi, M Takeda, Y Kanda, Y Sekino, Y Yoshida, JK Yamashita
PLoS ONE, 2020-11-02;15(11):e0241287.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Machine learning identifies abnormal Ca2+ transients in human induced pluripotent stem cell-derived cardiomyocytes
Authors: H Hwang, R Liu, JT Maxwell, J Yang, C Xu
Sci Rep, 2020-10-12;10(1):16977.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development
Authors: EI Crosse, S Gordon-Key, S Rybtsov, A Binagui-Ca, H Felchle, NC Nnadi, K Kirschner, T Chandra, S Tamagno, DJ Webb, F Rossi, RA Anderson, A Medvinsky
Cell Stem Cell, 2020-09-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
Res Sq, 2020-09-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Drug-Induced Na�ve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic &beta-Cell Lineage
Authors: Y Kiyokawa, M Sato, H Noguchi, E Inada, Y Iwase, N Kubota, T Sawami, M Terunuma, T Maeda, H Hayasaki, I Saitoh
Journal of Clinical Medicine, 2020-09-02;9(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State
Authors: L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton
Cell Stem Cell, 2020-08-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel ex vivo disease model for extramammary Paget�s disease using the cancer tissue-originated spheroid method
Authors: T Arita, J Kondo, Y Kaneko, M Tsutsumi, M Kanemaru, M Matsui, Y Arakawa, N Katoh, M Inoue, J Asai
J. Dermatol. Sci., 2020-08-05;0(0):.
Species: Human
Sample Types: Spheroids, Whole Cells
Applications: Bioassay

Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells
Authors: M Chen, M Maimaitili, M Habekost, KP Gill, N Mermet-Jor, S Nabavi, F Febbraro, M Denham
Stem Cell Res, 2020-08-03;48(0):101945.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential
Authors: SI Mae, M Ryosaka, S Sakamoto, K Matsuse, A Nozaki, M Igami, R Kabai, A Watanabe, K Osafune
Cell Rep, 2020-07-28;32(4):107963.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells
Authors: NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton
Cell Rep, 2020-07-14;32(2):107894.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Targeting all transforming growth factor-&beta isoforms with a Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer
Authors: K Takahashi, Y Akatsu, KA Podyma-Ino, T Matsumoto, H Takahashi, Y Yoshimatsu, D Koinuma, M Shirouzu, K Miyazono, T Watabe
J. Biol. Chem., 2020-07-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
Authors: LTP Khoa, YC Tsan, F Mao, DM Kremer, P Sajjakulnu, L Zhang, B Zhou, X Tong, NV Bhanu, C Choudhary, BA Garcia, L Yin, GD Smith, TL Saunders, SL Bielas, CA Lyssiotis, Y Dou
Cell Stem Cell, 2020-06-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
Authors: M Yagi, M Kabata, A Tanaka, T Ukai, S Ohta, K Nakabayash, M Shimizu, K Hata, A Meissner, T Yamamoto, Y Yamada
Nat Commun, 2020-06-24;11(1):3199.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
Authors: JW Blanchard, M Bula, J Davila-Vel, LA Akay, L Zhu, A Frank, MB Victor, JM Bonner, H Mathys, YT Lin, T Ko, DA Bennett, HP Cam, M Kellis, LH Tsai
Nat. Med., 2020-06-08;26(6):952-963.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
Authors: K Takeishi, A Collin de, Y Wang, K Handa, J Guzman-Lep, K Matsubara, K Morita, S Jang, N Haep, RM Florentino, F Yuan, K Fukumitsu, K Tobita, W Sun, J Franks, ER Delgado, EM Shapiro, NA Fraunhoffe, AW Duncan, H Yagi, T Mashimo, IJ Fox, A Soto-Gutie
Cell Rep, 2020-06-02;31(9):107711.
Species: Human
Sample Types: cell culture

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells
Authors: M Nafria, P Keane, ES Ng, EG Stanley, AG Elefanty, C Bonifer
Cell Rep, 2020-05-26;31(8):107691.
Species: Human
Sample Types:
Applications: Bioassay

TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes
Authors: H Liang, P Zhang, HJ Bai, J Huang, HT Yang
Stem Cell Res Ther, 2020-05-24;11(1):196.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Involvement of activin signal pathway in cyclic apoptosis of the oviductal isthmic epithelium in cows
Authors: Y Yamamoto, S Ito, K Okuda, K Kimura
Theriogenology, 2020-05-18;153(0):143-150.
Species: Bovine
Sample Types: Whole Cells
Applications: Cell Culture

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Authors: LSW Loo, AAP Soetedjo, HH Lau, NHJ Ng, S Ghosh, L Nguyen, VG Krishnan, H Choi, X Roca, S Hoon, AKK Teo
Cell Death Dis, 2020-05-18;11(5):378.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
Authors: Kumar Gupta A, Sarkar P, Wertheim J, Pan X, Carroll T, Oxburgh L
Commun Biol, 2020-05-11;3(1):231.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index
Authors: AL Thomas, K Castellano, G Mancinelli, Y Xia, J Bauer, C Yazici, G Fantuzzi, RF Hwang, NL Krett, GI Papachrist, DC Whitcomb, B Jung
Clin Transl Gastroenterol, 2020-05-01;11(5):e00152.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
Authors: NK Vinckier, NA Patel, RJ Geusz, A Wang, J Wang, I Matta, AR Harrington, M Wortham, N Wetton, J Wang, US Jhala, MG Rosenfeld, CW Benner, HP Shih, M Sander
Nat Commun, 2020-04-29;11(1):2082.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation
Authors: M Grosch, S Ittermann, E Rusha, T Greisle, C Ori, DJ Truong, AC O'Neill, A Pertek, GG Westmeyer, M Drukker
BMC Biol., 2020-04-22;18(1):42.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Notch signalling drives synovial fibroblast identity and arthritis pathology
Authors: K Wei, I Korsunsky, JL Marshall, A Gao, GFM Watts, T Major, AP Croft, J Watts, PE Blazar, JK Lange, TS Thornhill, A Filer, K Raza, LT Donlin, CW Siebel, CD Buckley, S Raychaudhu, MB Brenner
Nature, 2020-04-22;582(7811):259-264.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation
Authors: A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller
Mol Ther Methods Clin Dev, 2020-04-18;17(0):858-870.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells
Authors: H Tsujimoto, T Kasahara, SI Sueta, T Araoka, S Sakamoto, C Okada, SI Mae, T Nakajima, N Okamoto, D Taura, M Nasu, T Shimizu, M Ryosaka, Z Li, M Sone, M Ikeya, A Watanabe, K Osafune
Cell Rep, 2020-04-07;31(1):107476.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of intestinal organoids derived from human pluripotent stem cells for drug testing
Authors: S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi
Sci Rep, 2020-04-06;10(1):5989.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The translational landscape of ground state pluripotency
Authors: Y Atlasi, SM Jafarnejad, CG Gkogkas, M Vermeulen, N Sonenberg, HG Stunnenber
Nat Commun, 2020-04-01;11(1):1617.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Programmed Cell Death-1: Programmed Cell Death-Ligand 1 Interaction Protects Human Cardiomyocytes Against T-Cell Mediated Inflammation and Apoptosis Response In Vitro
Authors: WT Tay, YH Fang, ST Beh, YW Liu, LW Hsu, CJ Yen, PY Liu
Int J Mol Sci, 2020-03-31;21(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice
Authors: MJ Jeyarajah, G Jaju Bhatt, DM Hillier, SJ Renaud
Cells, 2020-03-31;9(4):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
Authors: A Plaza Reye, S Petrus-Reu, S Padrell Sá, P Kumar, I Douagi, H Bartuma, M Aronsson, S Westman, E Lardner, H André, A Falk, EF Nandrot, A Kvanta, F Lanner
Nat Commun, 2020-03-30;11(1):1609.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vascularized cardiac tissue construction with orientation by layer-by-layer method and 3D printer
Authors: Y Tsukamoto, T Akagi, M Akashi
Sci Rep, 2020-03-26;10(1):5484.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells
Authors: JL Hu, H Liang, H Zhang, MZ Yang, W Sun, P Zhang, L Luo, JX Feng, H Bai, F Liu, T Zhang, JY Yang, Q Gao, Y Long, XY Ma, Y Chen, Q Zhong, B Yu, S Liao, Y Wang, Y Zhao, MS Zeng, N Cao, J Wang, W Chen, HT Yang, S Gao
Nucleic Acids Res., 2020-03-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming
Authors: M Cangkrama, M Wietecha, N Mathis, R Okumura, L Ferrarese, D Al-Nuaimi, M Antsiferov, R Dummer, M Innocenti, S Werner
EMBO Mol Med, 2020-03-09;0(0):e11466.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
Authors: N Chanthra, T Abe, M Miyamoto, K Sekiguchi, C Kwon, Y Hanazono, H Uosaki
Sci Rep, 2020-03-06;10(1):4249.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets
Authors: M Liu, Q Yan, Y Sun, Y Nam, L Hu, JH Loong, Q Ouyang, Y Zhang, HL Li, FE Kong, L Li, Y Li, MM Li, W Cheng, LX Jiang, S Fang, XD Yang, JQ Mo, YF Gong, YQ Tang, Y Li, YF Yuan, NF Ma, G Lin, S Ma, JG Wang, XY Guan
Proc. Natl. Acad. Sci. U.S.A., 2020-03-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance
Authors: Y Toba, S Deguchi, N Mimura, A Sakamoto, K Harada, K Hirata, K Takayama, H Mizuguchi
PLoS ONE, 2020-02-27;15(2):e0229654.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
Authors: NJ Hogrebe, P Augsornwor, KG Maxwell, L Velazco-Cr, JR Millman
Nat. Biotechnol., 2020-02-24;0(0):.
Species: Human
Sample Types: Cells
Applications: Cell Culture

In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids
Authors: Y Yuan, L Li, Q Cheng, F Diao, Q Zeng, X Yang, Y Wu, H Zhang, M Huang, J Chen, Q Zhou, Y Zhu, R Hua, J Tian, X Wang, Z Zhou, J Hao, J Yu, D Hua, J Liu, X Guo, Q Zhou, J Sha
Cell Res., 2020-02-21;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
Authors: JP Gleeson, HQ Estrada, M Yamashita, CN Svendsen, SR Targan, RJ Barrett
Int J Mol Sci, 2020-02-20;21(4):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
Authors: Y Wang, L Lifshitz, K Gellatly, CL Vinton, K Busman-Sah, S McCauley, P Vangala, K Kim, A Derr, S Jaiswal, A Kucukural, P McDonel, PW Hunt, T Greenough, J Houghton, M Somsouk, JD Estes, JM Brenchley, M Garber, SG Deeks, J Luban
Nat. Immunol., 2020-02-17;21(3):274-286.
Species: Human
Sample Types: Cells

ER stress reliever enhances functionalities of in vitro cultured hepatocytes
Authors: JS Kim, SI Hwang, JL Ryu, HS Hong, JM Lee, SM Lee, X Jin, C Han, JH Kim, J Han, MR Lee, DH Woo
Stem Cell Res, 2020-02-12;43(0):101732.
Species: Human
Sample Types: cell culture
Applications: Bioassay

Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy
Authors: F Buljubasic, I El-Battraw, H Lan, SK Lomada, A Chatterjee, Z Zhao, X Li, R Zhong, Q Xu, M Huang, Z Liao, S Lang, L Cyganek, X Zhou, T Wieland, M Borggrefe, I Akin
J Clin Med, 2020-02-10;9(2):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors
Authors: LSW Loo, H Vethe, AAP Soetedjo, JA Paulo, J Jasmen, N Jackson, Y Bjørlykke, IA Valdez, M Vaudel, H Barsnes, SP Gygi, H Raeder, AKK Teo, RN Kulkarni
Stem Cells, 2020-01-22;0(0):.
Species: Human
Sample Types:
Applications: Bioassay

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca)
Authors: A Horváth, T Christ, JT Koivumäki, M Prondzynsk, ATL Zech, M Spohn, U Saleem, I Mannhardt, B Ulmer, E Girdauskas, C Meyer, A Hansen, T Eschenhage, MD Lemoine
Cells, 2020-01-20;9(1):.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts
Authors: JJ Weyers, JJ Gunaje, B Van Biber, A Martinson, H Reinecke, WM Mahoney, SM Schwartz, TC Cox, CE Murry
PLoS ONE, 2020-01-16;15(1):e0227780.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling
Authors: J Bauer, MAB Emon, JJ Staudacher, AL Thomas, J Zessner-Sp, G Mancinelli, N Krett, MT Saif, B Jung
Sci Rep, 2020-01-09;10(1):50.
Species: Human
Sample Types: cell culture
Applications: Cell Culture

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
Authors: A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley
Nat. Cell Biol., 2020-01-06;22(1):60-73.
Species: Mouse
Sample Types: Whole Cell
Applications: Cell Culture

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
Authors: W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho
Stem Cells, 2019-12-30;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BMPR2 acts as a�gatekeeper to protect endothelial cells from increased TGF&beta�responses and altered cell mechanics
Authors: C Hiepen, J Jatzlau, S Hildebrand, B Kampfrath, M Goktas, A Murgai, JL Cuellar Ca, R Haag, C Ruppert, G Sengle, EA Cavalcanti, KG Blank, P Knaus
PLoS Biol., 2019-12-11;17(12):e3000557.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Synergistic modulation of signaling pathways to expand and maintain the bipotency of human hepatoblasts
Authors: T Pan, Y Chen, Y Zhuang, F Yang, Y Xu, J Tao, K You, N Wang, Y Wu, X Lin, F Wu, Y Liu, Y Li, G Wang, YX Li
Stem Cell Res Ther, 2019-12-02;10(1):364.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
Authors: A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka
Nat Commun, 2019-11-29;10(1):5462.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies
Authors: K Kawai, R Negoro, M Ichikawa, T Yamashita, S Deguchi, K Harada, K Hirata, K Takayama, H Mizuguchi
Mol Ther Methods Clin Dev, 2019-11-21;17(0):49-57.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations
Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
Stem Cell Res, 2019-11-13;42(0):101657.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Involvement of CHOP in activin A?induced myeloma NS?1 cell apoptosis
Authors: J Ge, H Sun, J Li, Y Shan, Y Zhao, F Liao, Y Yang, X Cui, Z Liu
Oncol. Rep., 2019-10-22;0(0):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
Authors: T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim
Nat Commun, 2019-10-11;10(1):4647.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Engineering transferrable microvascular meshes for subcutaneous islet transplantation
Authors: W Song, A Chiu, LH Wang, RE Schwartz, B Li, N Bouklas, DT Bowers, D An, SH Cheong, JA Flanders, Y Pardo, Q Liu, X Wang, VK Lee, G Dai, M Ma
Nat Commun, 2019-10-10;10(1):4602.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved
Authors: I Guerriero, MT De Angelis, F D'Angelo, R Leveque, E Savignano, L Roberto, V Lucci, P Mazzone, S Laurino, G Storto, A Nardelli, A Sgambato, M Ceccarelli, M De Felice, E Amendola, G Falco
Int J Mol Sci, 2019-10-03;20(19):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation
Authors: Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, CJA Ramachandr, DJ Hausenloy, TW Soong, Y Zhang
Nat Commun, 2019-09-27;10(1):4416.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2
Authors: FM Cernilogar, S Hasenöder, Z Wang, K Scheibner, I Burtscher, M Sterr, P Smialowski, S Groh, IM Evenroed, GD Gilfillan, H Lickert, G Schotta
Nucleic Acids Res., 2019-09-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling
Authors: M Luo, J Bai, B Liu, P Yan, F Zuo, H Sun, Y Sun, X Xu, Z Song, Y Yang, J Massagué, X Lan, Z Lu, YG Chen, H Deng, W Xie, Q Xi
Stem Cell Reports, 2019-09-26;13(4):642-656.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals
Authors: GE Gentsch, T Spruce, NDL Owens, JC Smith
Nat Commun, 2019-09-19;10(1):4269.
Species: Xenopus
Sample Types: Tissue Explant
Applications: Bioassay

Controlled modelling of human epiblast and amnion development using stem cells
Authors: Y Zheng, X Xue, Y Shao, S Wang, SN Esfahani, Z Li, JM Muncie, JN Lakins, VM Weaver, DL Gumucio, J Fu
Nature, 2019-09-11;573(7774):421-425.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes
Authors: HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang
Stem Cells, 2019-08-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
Authors: C Song, F Xu, Z Ren, Y Zhang, Y Meng, Y Yang, S Lingadahal, E Cheung, G Li, W Liu, J Wan, Y Zhao, G Chen
Stem Cell Reports, 2019-07-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Authors: S Pecha, K Yorgan, M Röhl, B Geertz, A Hansen, F Weinberger, S Sehner, H Ehmke, H Reichenspu, T Eschenhage, AP Schwoerer
Sci Rep, 2019-07-08;9(1):9831.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells
Authors: KB Jung, O Kwon, MO Lee, H Lee, YS Son, O Habib, JH Oh, HS Cho, CR Jung, J Kim, MY Son
J Clin Med, 2019-07-04;8(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chemically Defined Media Can Maintain Pig Pluripotency Network In�Vitro
Authors: KH Choi, DK Lee, SW Kim, SH Woo, DY Kim, CK Lee
Stem Cell Reports, 2019-06-27;13(1):221-234.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay

Generation of human iPS cell-derived intestinal epithelial cell monolayers by CDX2 transduction
Authors: K Takayama, R Negoro, T Yamashita, K Kawai, M Ichikawa, T Mori, N Nakatsu, K Harada, S Ito, H Yamada, Y Yamaura, K Hirata, S Ishida, H Mizuguchi
Cell Mol Gastroenterol Hepatol, 2019-06-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Authors: M Prajapati-, A Benito-Gon, EJ Golden, S Zhang, A Doetzlhofe
Elife, 2019-06-12;8(0):.
Species: Mouse, Transgenic Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Cell cycle dynamics of human pluripotent stem cells primed for differentiation
Authors: A Shcherbina, J Li, C Narayanan, W Greenleaf, A Kundaje, S Chetty
Stem Cells, 2019-06-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture
Authors: M Shinohara, H Choi, M Ibuki, SG Yabe, H Okochi, A Miyajima, Y Sakai
Regen Ther, 2019-05-30;12(0):14-19.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice
Authors: Q Jin, C Qiao, J Li, B Xiao, J Li, X Xiao
Skelet Muscle, 2019-05-27;9(1):16.
Species: Human
Sample Types: Cell Lysates
Applications: Bioassay

Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development
Authors: N Sharon, J Vanderhoof, J Straubhaar, J Mueller, R Chawla, Q Zhou, EN Engquist, C Trapnell, DK Gifford, DA Melton
Cell Rep, 2019-05-21;27(8):2281-2291.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency
Authors: Y Atlasi, W Megchelenb, T Peng, E Habibi, O Joshi, SY Wang, C Wang, C Logie, I Poser, H Marks, HG Stunnenber
Nat. Cell Biol., 2019-04-29;21(5):568-578.
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Adequate taylor couette flow-mediated shear stress is useful for dissociating human iPS cell-derived cell aggregates
Authors: K Matsuura, M Wada, K Sakaguchi, Y Matsuhashi, T Shimizu
Regen Ther, 2019-04-25;12(0):6-13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

User-defined morphogen patterning for directing human cell fate stratification
Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
Sci Rep, 2019-04-23;9(1):6433.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animals
Authors: JH Kim, JH Kim, LA Sutikno, SB Lee, DH Jin, YK Hong, YS Kim, HJ Jin
PLoS ONE, 2019-04-18;14(4):e0215298.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
Cell Rep, 2019-04-16;27(3):708-718.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Delivery of pancreatic digestive enzymes into the gastrointestinal tract by pancreatic exocrine tissue transplant
Authors: K Ito, K Matsuura, Y Mihara, Y Sakamoto, K Hasegawa, N Kokudo, T Shimizu
Sci Rep, 2019-04-11;9(1):5922.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
Cell Rep, 2019-04-09;27(2):599-615.e12.
Species: Human
Sample Types: cell culture
Applications: Differentiation, Differentiation

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing ? cells
Authors: EA Rosado-Oli, K Anderson, JH Kenty, DA Melton
Nat Commun, 2019-04-01;10(1):1464.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold
Authors: T Minami, T Ishii, K Yasuchika, K Fukumitsu, S Ogiso, Y Miyauchi, H Kojima, T Kawai, R Yamaoka, Y Oshima, H Kawamoto, M Kotaka, K Yasuda, K Osafune, S Uemoto
Regen Ther, 2019-03-30;10(0):127-133.
Species: Human
Sample Types: Liver hiPSCs
Applications: Cell Culture

Point mutations in the PDX1 transactivation domain impair human ?-cell development and function
Authors: X Wang, M Sterr, Ansarullah, I Burtscher, A Böttcher, J Beckenbaue, J Siehler, T Meitinger, HU Häring, H Staiger, FM Cernilogar, G Schotta, M Irmler, J Beckers, CVE Wright, M Bakhti, H Lickert
Mol Metab, 2019-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
Cell Stem Cell, 2019-03-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FGF signal is not required for hepatoblast differentiation of human iPS cells
Authors: Y Toba, A Kiso, S Nakamae, F Sakurai, K Takayama, H Mizuguchi
Sci Rep, 2019-03-06;9(1):3713.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair
Authors: T Colunga, M Hayworth, S Kre beta, DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton
Cell Rep, 2019-03-05;26(10):2566-2579.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on L-Dopa induced dyskinesia
Authors: P Rentsch, S Stayte, GP Morris, B Vissel
BMC Neurosci, 2019-02-13;20(1):5.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
Authors: E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa
Sci Rep, 2019-02-13;9(1):1881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Excess growth hormone suppresses DNA damage repair in epithelial cells
Authors: V Chesnokova, S Zonis, R Barrett, H Kameda, K Wawrowsky, A Ben-Shlomo, M Yamamoto, J Gleeson, C Bresee, V Gorbunova, S Melmed
JCI Insight, 2019-02-07;4(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cell population balance of cardiovascular spheroids derived from human induced pluripotent stem cells
Authors: Y Yan, J Bejoy, J Xia, K Griffin, J Guan, Y Li
Sci Rep, 2019-02-04;9(1):1295.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of lung organoids from human pluripotent stem cells in vitro
Authors: AJ Miller, BR Dye, D Ferrer-Tor, DR Hill, AW Overeem, LD Shea, JR Spence
Nat Protoc, 2019-02-01;14(2):518-540.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differentiation and isolation of iPSC-derived remodeling ductal plate-like cells by use of an AQP1-GFP reporter human iPSC line
Authors: S Matsui, M Ochiai, K Yasuda, SI Mae, M Kotaka, T Toyoda, T Yamamoto, K Osafune
Stem Cell Res, 2019-01-31;35(0):101400.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors
Authors: H Noguchi, C Miyagi-Shi, Y Nakashima, T Kinjo, N Kobayashi, I Saitoh, M Watanabe, AMJ Shapiro, T Kin
Mol Ther Methods Clin Dev, 2019-01-29;13(0):243-252.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An in vitro model for studying CNS white matter: functional properties and experimental approaches
Authors: S Bijland, G Thomson, M Euston, K Michail, K Thümmler, S Mücklisch, CL Crawford, SC Barnett, M McLaughlin, TJ Anderson, C Linington, ER Brown, ER Kalkman, JM Edgar
F1000Res, 2019-01-29;8(0):117.
Species: Mouse
Sample Types: Embryonic Spinal Cord Cells
Applications: Bioassay

An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
Authors: L Liu, L Leng, C Liu, C Lu, Y Yuan, L Wu, F Gong, S Zhang, X Wei, M Wang, L Zhao, L Hu, J Wang, H Yang, S Zhu, F Chen, G Lu, Z Shang, G Lin
Nat Commun, 2019-01-21;10(1):364.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells
Authors: A Montel-Hag, CS Seet, S Li, B Chick, Y Zhu, P Chang, S Tsai, V Sun, S Lopez, HC Chen, C He, CJ Chin, D Casero, GM Crooks
Cell Stem Cell, 2019-01-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Establishing Liposome-Immobilized Dexamethasone-Releasing PDMS Membrane for the Cultivation of Retinal Pigment Epithelial Cells and Suppression of Neovascularization
Authors: TW Lin, Y Chien, YY Lin, ML Wang, AA Yarmishyn, YP Yang, DK Hwang, CH Peng, CC Hsu, SJ Chen, KH Chien
Int J Mol Sci, 2019-01-09;20(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
Authors: MA Scavuzzo, J Chmielowie, D Yang, K Wamble, LS Chaboub, L Duraine, B Tepe, SM Glasgow, BR Arenkiel, C Brou, B Deneen, M Borowiak
Cell Rep, 2018-12-26;25(13):3811-3827.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family
Authors: J Li, C Narayanan, J Bian, D Sambo, T Brickler, W Zhang, S Chetty
PLoS ONE, 2018-12-12;13(12):e0208110.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies
Authors: R Negoro, K Takayama, K Kawai, K Harada, F Sakurai, K Hirata, H Mizuguchi
Stem Cell Reports, 2018-11-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Klf5 suppresses ERK signaling in mouse pluripotent stem cells
Authors: T Azami, K Matsumoto, H Jeon, T Waku, M Muratani, H Niwa, S Takahashi, M Ema
PLoS ONE, 2018-11-19;13(11):e0207321.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
Authors: H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys
Cell Stem Cell, 2018-11-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis
Authors: A Jørgensen, J Macdonald, JE Nielsen, KR Kilcoyne, S Perlman, L Lundvall, L Langhoff T, K Juul Hare, H Frederikse, AM Andersson, NE Skakkebæk, A Juul, RM Sharpe, E Rajpert-De, RT Mitchell
Cell Rep, 2018-11-13;25(7):1924-1937.e4.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The plant alkaloid conophylline inhibits matrix formation of fibroblasts
Authors: T Tezuka, A Ota, S Karnan, K Matsuura, K Yokoo, Y Hosokawa, D Vigetti, A Passi, S Hatano, K Umezawa, H Watanabe
J. Biol. Chem., 2018-10-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Stimulation

Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors
Authors: H Ida, T Akiyama, K Ishiguro, SK Goparaju, Y Nakatake, N Chikazawa-, S Sato, H Kimura, Y Yokoyama, M Nagino, MSH Ko, SBH Ko
Stem Cell Res Ther, 2018-10-25;9(1):277.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
Elife, 2018-10-12;7(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analyzing bovine OCT4 and NANOG enhancer activity in pluripotent stem cells using fluorescent protein reporters
Authors: D Huang, L Wang, NC Talbot, C Huang, L Pu, X Zhao, X Tian, M Zhang, Y Tang
PLoS ONE, 2018-10-05;13(10):e0203923.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
Cell Stem Cell, 2018-09-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects
Authors: A Yoshida, JK Lee, S Tomoyama, K Miwa, K Shirakawa, S Hamanaka, T Yamaguchi, H Nakauchi, S Miyagawa, Y Sawa, I Komuro, Y Sakata
Europace, 2018-09-01;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.
Authors: Bajaj P, Rodrigues A, Steppan C, Engle S, Mathialagan S, Schroeter T
Drug Metab Dispos, 2018-08-31;46(11):1703-1711.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of a Graphene Oxide-Incorporated Polydimethylsiloxane Membrane with Hexagonal Micropillars
Authors: YY Lin, Y Chien, JH Chuang, CC Chang, YP Yang, YH Lai, WL Lo, KH Chien, TI Huo, CY Wang
Int J Mol Sci, 2018-08-25;19(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis
Authors: MA Scavuzzo, MC Hill, J Chmielowie, D Yang, J Teaw, K Sheng, Y Kong, M Bettini, C Zong, JF Martin, M Borowiak
Nat Commun, 2018-08-22;9(1):3356.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes
Authors: A Skrzypczyk, S Kehr, I Krystel, SH Bernhart, S Giri, A Bader, PF Stadler
Stem Cells Int, 2018-08-19;2018(0):5692840.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA
Authors: C Miyagi-Shi, Y Nakashima, N Kobayashi, I Saitoh, M Watanabe, H Noguchi
Sci Rep, 2018-08-17;8(1):12341.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tributyltin Inhibits Neural Induction of Human Induced Pluripotent Stem Cells
Authors: S Yamada, Y Kubo, D Yamazaki, Y Sekino, Y Nomura, S Yoshida, Y Kanda
Sci Rep, 2018-08-14;8(1):12155.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cardiomyocytes Derived from Human CardiopoieticAmniotic Fluids
Authors: A Di Baldass, MA D'Amico, P Izzicupo, G Gaggi, S Guarnieri, MA Mariggiò, I Antonucci, B Corneo, D Sirabella, L Stuppia, B Ghinassi
Sci Rep, 2018-08-13;8(1):12028.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
Authors: Z Xu, X He, X Shi, Y Xia, X Liu, H Wu, P Li, H Zhang, W Yin, X Du, L Li, Y Li
Stem Cell Res Ther, 2018-08-09;9(1):211.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Precardiac organoids form two heart fields via Bmp/Wnt signaling
Authors: P Andersen, E Tampakakis, DV Jimenez, S Kannan, M Miyamoto, HK Shin, A Saberi, S Murphy, E Sulistio, SP Chelko, C Kwon
Nat Commun, 2018-08-07;9(1):3140.
Species: Mouse
Sample Types: Spheroids
Applications: Bioassay

A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo
Authors: A Spangler, EY Su, AM Craft, P Cahan
Stem Cell Res, 2018-07-29;31(0):201-215.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells
Authors: M Shoji, H Minato, S Ogaki, M Seki, Y Suzuki, S Kume, T Kuzuhara
PLoS ONE, 2018-07-26;13(7):e0201239.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids
Authors: E Magro-Lope, C Palmer, J Manso, I Liste, A Zambrano
Stem Cell Res Ther, 2018-07-11;9(1):186.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Preparation of iPS cell-derived CD31+ endothelial cells using three-dimensional suspension culture
Authors: S Masuda, K Matsuura, T Shimizu
Regen Ther, 2018-07-07;9(0):1-9.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis
Authors: MA Deutsch, SA Doppler, X Li, H Lahm, G Santamaria, G Cuda, S Eichhorn, T Ratschille, E Dzilic, M Dre beta en, A Eckart, K Stark, S Massberg, A Bartels, C Rischpler, R Gilsbach, L Hein, BK Fleischman, SM Wu, R Lange, M Krane
Cardiovasc. Res., 2018-07-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
Authors: K Koefoed, J Skat-Rørda, P Andersen, CB Warzecha, M Pye, TA Andersen, KD Ajbro, E Bendsen, M Narimatsu, F Vilhardt, LB Pedersen, JL Wrana, RH Anderson, K Møllgård, ST Christense, LA Larsen
Sci Rep, 2018-06-22;8(1):9542.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells
Authors: F Zambelli, J Mertens, D Dziedzicka, J Sterckx, C Markouli, A Keller, P Tropel, L Jung, S Viville, H Van de Vel, M Geens, S Seneca, K Sermon, C Spits
Stem Cell Reports, 2018-06-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages
Authors: J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao
Cell Transplant, 2018-06-13;0(0):9636897187803.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TGF? signaling hyperactivation-induced tumorigenicity during the derivation of neural progenitors from mouse ESCs
Authors: X Yang, R Wang, X Wang, G Cai, Y Qian, S Feng, F Tan, K Chen, K Tang, X Huang, N Jing, Y Qiao
J Mol Cell Biol, 2018-06-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
Authors: RP Russell, Y Fu, Y Liu, P Maye
Stem Cell Res, 2018-05-22;30(0):85-95.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Functional comparison of distinct Brachyury+ states in a renal differentiation assay
Authors: J Zhou, A Plagge, P Murray
Biol Open, 2018-05-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
Cell Stem Cell, 2018-05-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
Authors: L Galvan, L Francelle, MC Gaillard, L de Longpre, MA Carrillo-d, G Liot, K Cambon, L Stimmer, S Luccantoni, J Flament, J Valette, M de Chaldée, G Auregan, M Guillermie, C Joséphine, F Petit, C Jan, M Jarrige, N Dufour, G Bonvento, S Humbert, F Saudou, P Hantraye, K Merienne, AP Bemelmans, AL Perrier, N Déglon, E Brouillet
Brain, 2018-05-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
Authors: J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, WM Cao, D Sun, R Xie, Y Huang
Nucleic Acids Res., 2018-04-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery
Authors: Y Jin, Y Liu, Z Li, K Santostefa, J Shi, X Zhang, D Wu, Z Cheng, W Wu, N Terada, S Jin, F Bai
PLoS ONE, 2018-03-26;13(3):e0194895.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells
Authors: J Tu, G Tian, HH Cheung, W Wei, TL Lee
Stem Cell Res Ther, 2018-03-21;9(1):71.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Beta-Catenin maintains lung epithelial progenitors after lung specification
Authors: EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen
Development, 2018-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes
Authors: A Schöbel, K Rösch, E Herker
Sci Rep, 2018-03-01;8(1):3893.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
Authors: RR Zhang, M Koido, T Tadokoro, R Ouchi, T Matsuno, Y Ueno, K Sekine, T Takebe, H Taniguchi
Stem Cell Reports, 2018-02-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
Front Cell Dev Biol, 2018-02-06;6(0):5.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Activin receptors regulate the oligodendrocyte lineage in health and disease
Authors: A Dillenburg, G Ireland, RK Holloway, CL Davies, FL Evans, M Swire, ME Bechler, D Soong, TJ Yuen, GH Su, JC Becher, C Smith, A Williams, VE Miron
Acta Neuropathol., 2018-02-03;0(0):.
Species: Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: Bioassay, Cell Culture, Tissue Culture

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva
Authors: JB Lees-Shepa, M Yamamoto, AA Biswas, SJ Stoessel, SE Nicholas, CA Cogswell, PM Devarakond, MJ Schneider, SM Cummins, NP Legendre, S Yamamoto, V Kaartinen, JW Hunter, DJ Goldhamer
Nat Commun, 2018-02-02;9(1):471.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells
Authors: T Yamashita, K Takayama, F Sakurai, H Mizuguchi
Biochem. Biophys. Res. Commun., 2018-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation

Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B
Authors: R Okamoto, K Takayama, N Akita, Y Nagamoto, D Hosokawa, S Iizuka, F Sakurai, H Suemizu, K Ohashi, H Mizuguchi
Cell Transplant, 2018-02-01;27(2):299-309.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
Authors: C Long, H Li, M Tiburcy, C Rodriguez-, V Kyrychenko, H Zhou, Y Zhang, YL Min, JM Shelton, PPA Mammen, NY Liaw, WH Zimmermann, R Bassel-Dub, JW Schneider, EN Olson
Sci Adv, 2018-01-31;4(1):eaap9004.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors
Authors: X Wang, M Sterr, I Burtscher, S Chen, A Hieronimus, F Machicao, H Staiger, HU Häring, G Lederer, T Meitinger, FM Cernilogar, G Schotta, M Irmler, J Beckers, M Hrab? de A, M Ray, CVE Wright, M Bakhti, H Lickert
Mol Metab, 2018-01-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
Mol. Syst. Biol., 2018-01-29;14(1):e7952.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
Sci Rep, 2018-01-24;8(1):1561.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein-Gremlin signaling pathways
Authors: KE Tumelty, N Higginson-, X Fan, P Bajaj, KM Knowlton, M Shamashkin, AJ Coyle, W Lu, SP Berasi
J. Biol. Chem., 2018-01-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Overlapping functions of Krüppel-like factor family members: targeting multiple transcription factors to maintain the naïve pluripotency of mouse embryonic stem cells
Authors: Mariko Yamane, Satoshi Ohtsuka, Kumi Matsuura, Akira Nakamura, Hitoshi Niwa
Development
Species: Transgenic Mouse
Sample Types: Whole Cells, Transfected Whole Cells
Applications: Bioassay

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
Cellular and Molecular Gastroenterology and Hepatology, 2017-12-29;0(0):2352-345X.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells
Authors: MG Perino, S Yamanaka, DR Riordon, Y Tarasova, KR Boheler
PLoS ONE, 2017-12-12;12(12):e0188569.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cells
Authors: M Kotaka, T Toyoda, K Yasuda, Y Kitano, C Okada, A Ohta, A Watanabe, M Uesugi, K Osafune
Sci Rep, 2017-12-01;7(1):16734.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver
Authors: WS Fagg, N Liu, MJ Yang, K Cheng, E Chung, JS Kim, G Wu, J Fair
Cell Transplant, 2017-12-01;26(12):1868-1877.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice
Authors: YY Sin, LL Ballantyne, CR Richmond, CD Funk
Mol Ther Nucleic Acids, 2017-12-01;10(0):122-130.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rapid DNA replication origin licensing protects stem cell pluripotency
Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
Elife, 2017-11-17;6(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
Authors: A Taguchi, R Nishinakam
Cell Stem Cell, 2017-11-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Derivation of hypermethylated pluripotent embryonic stem cells with high potency
Authors: S Bao, WW Tang, B Wu, S Kim, J Li, L Li, T Kobayashi, C Lee, Y Chen, M Wei, S Li, S Dietmann, F Tang, X Li, MA Surani
Cell Res., 2017-10-27;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effects of Aminoglycoside Antibiotics on Human Embryonic Stem Cell Viability during Differentiation In Vitro
Authors: DS Varghese, S Parween, MT Ardah, BS Emerald, SA Ansari
Stem Cells Int, 2017-09-24;2017(0):2451927.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes
Authors: N Merienne, G Vachey, L de Longpre, C Meunier, V Zimmer, G Perriard, M Canales, A Mathias, L Herrgott, T Beltramine, A Maulet, T Dequesne, C Pythoud, M Rey, L Pellerin, E Brouillet, AL Perrier, R du Pasquie, N Déglon
Cell Rep, 2017-09-19;20(12):2980-2991.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening
Authors: ZQ He, BL Xia, YK Wang, J Li, GH Feng, LL Zhang, YH Li, HF Wan, TD Li, K Xu, XW Yuan, YF Li, XX Zhang, Y Zhang, L Wang, W Li, Q Zhou
Cell Rep, 2017-08-29;20(9):2227-2237.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
Authors: KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro
Nat Commun, 2017-08-24;8(1):331.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
Authors: NG Kooreman, PE de Almeida, JP Stack, RV Nelakanti, S Diecke, NY Shao, RJ Swijnenbur, V Sanchez-Fr, E Matsa, C Liu, AJ Connolly, JF Hamming, PHA Quax, MA Brehm, DL Greiner, LD Shultz, JC Wu
Cell Rep, 2017-08-22;20(8):1978-1990.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity
Authors: S Merfeld-Cl, H Lu, X Wu, KL March, DO Traktuev
J. Cell. Mol. Med., 2017-08-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
Sci Rep, 2017-08-17;7(1):8491.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
Cell Rep, 2017-08-15;20(7):1597-1608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased expression of apoptosis-related genes
Authors: Y Hosokawa, T Toyoda, K Fukui, MY Baden, M Funato, Y Kondo, T Sudo, H Iwahashi, M Kishida, C Okada, A Watanabe, I Asaka, K Osafune, A Imagawa, I Shimomura
J Diabetes Investig, 2017-08-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A pluripotent stem cell-based model for post-implantation human amniotic sac development
Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
Nat Commun, 2017-08-08;8(1):208.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell Stem Cell, 2017-08-03;21(2):179-194.e4.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors
Authors: M Sambi, T Chow, J Whiteley, M Li, S Chua, V Raileanu, IM Rogers
Stem Cell Rev, 2017-08-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
Authors: K Hino, K Horigome, M Nishio, S Komura, S Nagata, C Zhao, Y Jin, K Kawakami, Y Yamada, A Ohta, J Toguchida, M Ikeya
J. Clin. Invest., 2017-07-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells
Authors: C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat
J. Biol. Chem., 2017-07-26;0(0):.
Species: Ovine
Sample Types: Whole Cells
Applications: Bioassay

Activin signaling is an essential component of the TGF-? induced pro-metastatic phenotype in colorectal cancer
Authors: JJ Staudacher, J Bauer, A Jana, J Tian, T Carroll, G Mancinelli, Ö Özden, N Krett, G Guzman, D Kerr, P Grippo, B Jung
Sci Rep, 2017-07-17;7(1):5569.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation
Authors: M Ito, S Sun, T Fukuhara, R Suzuki, M Tamai, T Yamauchi, K Nakashima, YI Tagawa, S Okazaki, Y Matsuura, T Wakita, T Suzuki
Oncotarget, 2017-07-08;8(33):53899-53915.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin Receptor Type IIA (ACVR2A) Functions Directly in Osteoblasts as a Negative Regulator of Bone Mass
Authors: BC Goh, V Singhal, AJ Herrera, RE Tomlinson, S Kim, MC Faugere, EL Germain-Le, TL Clemens, SJ Lee, DJ DiGirolamo
J. Biol. Chem., 2017-06-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
Authors: AG Freire, A Waghray, F Soares-da-, TP Resende, DF Lee, CF Pereira, DS Nascimento, IR Lemischka, P Pinto-do-Ó
Stem Cell Reports, 2017-06-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Authors: M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, NH Pipalia, HJ Chen, M Witherspoo, M Gordillo, JZ Xiang, FR Maxfield, S Lipkin, T Evans, S Chen
Nat. Med., 2017-06-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology
Authors: K Sakamoto, Y Kanematsu-, Y Kamada, M Oka, T Ohnishi, M Miwa, T Asami, H Inooka
Biochem Biophys Rep, 2017-06-10;11(0):33-39.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
Authors: G Yücel, Z Zhao, I El-Battraw, H Lan, S Lang, X Li, F Buljubasic, WH Zimmermann, L Cyganek, J Utikal, U Ravens, T Wieland, M Borggrefe, XB Zhou, I Akin
Sci Rep, 2017-06-07;7(1):2935.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Follistatin is a metastasis suppressor in a mouse model of HER2-positive breast cancer
Authors: DD Seachrist, ST Sizemore, E Johnson, FW Abdul-Kari, KL Weber Bonk, RA Keri
Breast Cancer Res., 2017-06-05;19(1):66.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols
Authors: D Jeziorowsk, V Fontaine, C Jouve, E Villard, S Dussaud, D Akbar, V Letang, P Cervello, JM Itier, MP Pruniaux, JS Hulot
Int J Mol Sci, 2017-06-01;18(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
Authors: YY Sin, PR Price, LL Ballantyne, CD Funk
Sci Rep, 2017-05-31;7(1):2585.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture
Authors: A Arauchi, K Matsuura, T Shimizu, T Okano
Front Endocrinol (Lausanne), 2017-05-22;8(0):103.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The N-glycome of embryonic stem cells and thereof differentiated hepatic cells
Authors: H Montacir, N Freyer, F Knoespel, T Urbaniak, T Dedova, M Berger, G Damm, R Tauber, K Zeilinger, V Blanchard
Chembiochem, 2017-05-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differentiation of cardiomyocytes and generation of human engineered heart tissue
Authors: K Breckwoldt, D Letuffe-Br, I Mannhardt, T Schulze, B Ulmer, T Werner, A Benzin, B Klampe, MC Reinsch, S Laufer, A Shibamiya, M Prondzynsk, G Mearini, D Schade, S Fuchs, C Neuber, E Krämer, U Saleem, ML Schulze, ML Rodriguez, T Eschenhage, A Hansen
Nat Protoc, 2017-05-11;12(6):1177-1197.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations
Authors: Q Gu, J Wang, L Wang, ZX Liu, WW Zhu, YQ Tan, WF Han, J Wu, CJ Feng, JH Fang, L Liu, L Wang, W Li, XY Zhao, BY Hu, J Hao, Q Zhou
Stem Cell Reports, 2017-05-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5
Authors: LK Bollum, K Huse, MP Oksvold, B Bai, VI Hilden, L Forfang, SO Yoon, S Wälchli, EB Smeland, JH Myklebust
PLoS ONE, 2017-05-10;12(5):e0177188.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency
Authors: M Sone, N Morone, T Nakamura, A Tanaka, K Okita, K Woltjen, M Nakagawa, JE Heuser, Y Yamada, S Yamanaka, T Yamamoto
Cell Metab., 2017-05-02;25(5):1103-1117.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells
Authors: JA Heslop, R Kia, CS Pridgeon, RL Sison-Youn, T Liloglou, M Elmasry, SW Fenwick, JS Mills, NR Kitteringh, CE Goldring, BK Park
Stem Cells Transl Med, 2017-05-01;6(5):1321-1331.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin A more prominently regulates muscle mass in primates than does GDF8
Authors: E Latres, J Mastaitis, W Fury, L Miloscio, J Trejos, J Pangilinan, H Okamoto, K Cavino, E Na, A Papatheodo, T Willer, Y Bai, J Hae Kim, A Rafique, S Jaspers, T Stitt, AJ Murphy, GD Yancopoulo, J Gromada
Nat Commun, 2017-04-28;8(0):15153.
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance

Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
Authors: K Low, LY Wong, M Maldonado, C Manjunath, CB Horner, M Perez, NV Myung, J Nam
Stem Cell Reports, 2017-04-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling
Authors: S Mitani, K Takayama, Y Nagamoto, K Imagawa, F Sakurai, M Tachibana, R Sumazaki, H Mizuguchi
Mol. Ther., 2017-04-24;25(6):1420-1433.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Authors: S Warrier, M Van der Je, G Duggal, L Tilleman, E Sutherland, J Taelman, M Popovic, S Lierman, S Chuva De S, A Van Soom, L Peelman, F Van Nieuwe, DIM De Coninck, B Menten, P Mestdagh, J Van de Som, D Deforce, P De Sutter, B Heindryckx
Nat Commun, 2017-04-21;8(0):15055.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells
Authors: K Hirano, S Konagaya, A Turner, Y Noda, S Kitamura, H Kotera, H Iwata
Biochem. Biophys. Res. Commun., 2017-04-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
Authors: EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, J Arbelaez, M Hernandez, N Kuperwasse, W Li, Z Lian, Y Liu, W Lv, SL Lytle-Gabb, DH Marchadier, P Rogov, J Shi, KJ Slovik, IM Stylianou, L Wang, R Yan, X Zhang, S Kathiresan, SA Duncan, TS Mikkelsen, EE Morrisey, DJ Rader, CD Brown, K Musunuru
Cell Stem Cell, 2017-04-06;20(4):558-570.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Supraphysiological levels of GDF11 induce striated muscle atrophy
Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
EMBO Mol Med, 2017-04-01;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
Nat Protoc, 2017-03-23;12(4):814-827.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
Authors: S Tousa, M Semitekolo, I Morianos, A Banos, AI Trochoutso, TM Brodie, N Poulos, K Samitas, M Kapasa, D Konstantop, G Paraskevop, M Gaga, CM Hawrylowic, F Sallusto, G Xanthou
Proc. Natl. Acad. Sci. U.S.A, 2017-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
Authors: A Asai, E Aihara, C Watson, R Mourya, T Mizuochi, P Shivakumar, K Phelan, C Mayhew, M Helmrath, T Takebe, J Wells, JA Bezerra
Development, 2017-03-15;144(6):1056-1064.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transplantation of multipotent Isl1+ cardiac progenitor cells preserves infarcted heart function in mice
Authors: Y Li, S Tian, I Lei, L Liu, P Ma, Z Wang
Am J Transl Res, 2017-03-15;9(3):1530-1542.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modelling urea-cycle disorder citrullinemia type 1 with disease-specific iPSCs
Authors: EY Yoshitoshi, T Toyoda, K Yasuda, M Kotaka, K Nomoto, K Okita, K Yasuchika, S Okamoto, N Takubo, T Nishikubo, T Soga, S Uemoto, K Osafune
Biochem. Biophys. Res. Commun, 2017-03-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGF? and Activin pathways
Authors: M García, R Barrio, M García-Lav, AR Garcia-Ren, A Escudero, E Díaz-Rodrí, D Gorbenko D, A Fernández, YB de Rijke, E Vallespín, J Nevado, P Lapunzina, V Matre, PM Hinkle, AC Hokken-Koe, MP de Miguel, JM Cameselle-, M Nistal, CV Alvarez, JC Moreno
Sci Rep, 2017-03-06;7(0):42937.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
Authors: K Yamamizu, M Iwasaki, H Takakubo, T Sakamoto, T Ikuno, M Miyoshi, T Kondo, Y Nakao, M Nakagawa, H Inoue, JK Yamashita
Stem Cell Reports, 2017-02-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
Authors: B Ulmer, M Tingler, S Kurz, M Maerker, P Andre, D Mönch, M Campione, K Dei beta ler, M Lewandoski, T Thumberger, A Schweicker, A Fainsod, H Steinbei beta e, M Blum
Sci Rep, 2017-02-21;7(0):43010.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
Development, 2017-02-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors
Authors: G Valenti, HM Quinn, GJ Heynen, L Lan, JD Holland, R Vogel, A Wulf-Golde, W Birchmeier
Cancer Res, 2017-02-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
Authors: N Cerdá-Este, H Naumann, S Ruzittu, N Mah, IM Pongrac, C Cozzitorto, A Hommel, MA Andrade-Na, E Bonifacio, FM Spagnoli
Nat Commun, 2017-02-13;8(0):14127.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentiation and characterization of rhesus monkey atrial and ventricular cardiomyocytes from induced pluripotent stem cells
Authors: X Zhang, H Cao, S Bai, W Huo, Y Ma
Stem Cell Res, 2017-02-11;20(0):21-29.
Species: Primate - Rhesus macaque
Sample Types: Whole Cells
Applications: Bioassay

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo
Authors: CS Simon, DJ Downes, ME Gosden, J Telenius, DR Higgs, JR Hughes, I Costello, EK Bikoff, EJ Robertson
Development, 2017-02-07;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Development of a human cardiac organoid injury model reveals innate regenerative potential
Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
Development, 2017-02-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair
Authors: M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, E Levent, F Raad, S Zeidler, E Wingender, J Riegler, M Wang, JD Gold, I Kehat, E Wettwer, U Ravens, P Dierickx, LW van Laake, MJ Goumans, S Khadjeh, K Toischer, G Hasenfuss, LA Couture, A Unger, WA Linke, T Araki, B Neel, G Keller, L Gepstein, JC Wu, WH Zimmermann
Circulation, 2017-02-06;135(19):1832-1847.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
Cell Stem Cell, 2017-01-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
Authors: Y Choudhury, YC Toh, J Xing, Y Qu, J Poh, L Huan, HS Tan, R Kanesvaran, H Yu, MH Tan
Sci Rep, 2017-01-25;7(0):41238.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo
Authors: S Stayte, P Rentsch, AR Tr”scher, M Bamberger, KM Li, B Vissel
PLoS ONE, 2017-01-25;12(1):e0167211.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Conserved miR-10 family represses proliferation and induces apoptosis in ovarian granulosa cells
Authors: T Jiajie, Y Yanzhou, AC Hoi-Hung, C Zi-Jiang, C Wai-Yee
Sci Rep, 2017-01-23;7(0):41304.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
Authors: S Kadota, L Pabon, H Reinecke, CE Murry
Stem Cell Reports, 2017-01-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TAZ induction directs differentiation of thyroid follicular cells from human embryonic stem cells
Authors: Terry F Davies
Thyroid, 2017-01-03;0(0):.
Species: Human
Sample Types: Whole Cells

Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages
EMBO Mol Med, 2017-01-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells
Nat Protoc, 2016-12-22;12(1):195-207.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Repressed SIRT1/PGC-1? pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration
J Transl Med, 2016-12-20;14(1):344.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SMAD3 Regulates Follicle-Stimulating Hormone Synthesis by Pituitary Gonadotrope Cells In Vivo
Authors: Yining Li
J. Biol. Chem, 2016-12-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events
Authors: Silvia Parisi
FASEB J, 2016-12-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
Nat Protoc, 2016-12-01;12(1):15-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Are Adipose-Derived Stem Cells From Liver Falciform Ligaments Another Possible Source of Mesenchymal Stem Cells?
Authors: SW Lee, JU Chong, SO Min, SY Bak, KS Kim
Cell Transplant, 2016-11-24;26(5):855-866.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells
Authors: Joan Massagué
Cell Stem Cell, 2016-11-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016-11-14;22(12):1421-1427.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nemo-like kinase 1 (Nlk1) and paraxial protocadherin (PAPC) cooperatively control Xenopus gastrulation through regulation of Wnt/planar cell polarity (PCP) signaling
Authors: Lilian T Kaufmann
Differentiation, 2016-10-28;93(0):27-38.
Applications: Bioassay

Activin A/Smads signaling pathway negatively regulates Oxygen Glucose Deprivation-induced autophagy via suppression of JNK and p38 MAPK pathways in neuronal PC12 cells
Authors: Long-Xing Xue
Biochem. Biophys. Res. Commun, 2016-10-18;480(3):355-361.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Transient RUNX1 Expression during Early Mesendodermal Differentiation of�hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling
Stem Cell Reports, 2016-10-06;7(5):884-896.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose
PLoS ONE, 2016-09-23;11(9):e0163580.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A strategy to ensure safety of stem cell-derived retinal pigment epithelium cells
Stem Cell Res Ther, 2016-09-02;7(1):127.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fscn1 is required for the trafficking of TGF-? family type I receptors during endoderm formation
Nat Commun, 2016-08-22;7(0):12603.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
Stem Cell Res Ther, 2016-08-17;7(1):115.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification
Proc Natl Acad Sci USA, 2016-08-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells
PLoS ONE, 2016-07-13;11(7):e0159246.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin A programs the differentiation of human TFH cells
Nat Immunol, 2016-07-04;17(8):976-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Growth hormone is permissive for neoplastic colon growth
Proc Natl Acad Sci USA, 2016-05-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Response to Extrinsic Bone Morphogenetic Protein (BMP) Signaling
Authors: L Song, J Chen, G Peng, K Tang, N Jing
J. Biol. Chem., 2016-05-16;291(29):15212-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
Stem Cells Transl Med, 2016-01-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transplantation of Donor-Origin Mouse Embryonic Stem Cell-Derived Thymic Epithelial Progenitors Prevents the Development of Chronic Graft-Versus-Host Disease in Mice
Stem Cells Transl Med, 2016-01-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
Authors: Robert Thomas
Biotechnol. Prog., 2015-11-28;32(1):215-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nephron organoids derived from human pluripotent stem cells model kidney development and injury.
Authors: Morizane R, Lam A, Freedman B, Kishi S, Valerius M, Bonventre J
Nat Biotechnol, 2015-11-01;33(11):1193-200.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice.
Authors: Latres E, Pangilinan J, Miloscio L, Bauerlein R, Na E, Potocky T, Huang Y, Eckersdorff M, Rafique A, Mastaitis J, Lin C, Murphy A, Yancopoulos G, Gromada J, Stitt T
Skelet Muscle, 2015-10-09;5(0):34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.
Authors: Bufalino A, Cervigne N, de Oliveira C, Fonseca F, Rodrigues P, Macedo C, Sobral L, Miguel M, Lopes M, Paes Leme A, Lambert D, Salo T, Kowalski L, Graner E, Coletta R
PLoS ONE, 2015-08-28;10(8):e0136599.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells.
Authors: Nagaoka M, Kobayashi M, Kawai C, Mallanna S, Duncan S
PLoS ONE, 2015-08-26;10(8):e0136350.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells.
Authors: Yang W, Liu Y, Slovik K, Wu J, Duncan S, Rader D, Morrisey E
PLoS ONE, 2015-08-17;10(8):e0134995.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy.
Authors: Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y
PLoS ONE, 2015-07-30;10(7):e0133713.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure.
Authors: Calderon-Gierszal E, Prins G
PLoS ONE, 2015-07-29;10(7):e0133238.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin Regulates Self-renewal and Differentiation of Trophoblast Stem Cells by Down-regulating the X Chromosome Gene Bcor.
Authors: Zhu G, Fei T, Li Z, Yan X, Chen Y
J Biol Chem, 2015-07-28;290(36):22019-29.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.
Authors: Gerbin K, Yang X, Murry C, Coulombe K
PLoS ONE, 2015-07-10;10(7):e0131446.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A.
Authors: Merfeld-Clauss S, Lupov I, Lu H, March K, Traktuev D
Stem Cells, 2015-07-03;33(10):3039-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alternative Routes to Induce Naive Pluripotency in Human Embryonic Stem Cells.
Authors: Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker R, Heijmans B, Deforce D, De Sutter P, de Sousa Lopes S, Heindryckx B
Stem Cells, 2015-06-24;33(9):2686-98.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DNA methylation directs functional maturation of pancreatic beta cells.
Authors: Dhawan S, Tschen S, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A
J Clin Invest, 2015-06-22;125(7):2851-60.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Follistatin288 Regulates Germ Cell Cyst Breakdown and Primordial Follicle Assembly in the Mouse Ovary.
Authors: Wang Z, Niu W, Wang Y, Teng Z, Wen J, Xia G, Wang C
PLoS ONE, 2015-06-15;10(6):e0129643.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity.
Authors: Gancarz A, Wang Z, Schroeder G, Damez-Werno D, Braunscheidel K, Mueller L, Humby M, Caccamise A, Martin J, Dietz K, Neve R, Dietz D
Nat Neurosci, 2015-06-01;18(7):959-61.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of Receptor-regulated Smads (R-Smads) to Ensure Transforming Growth Factor beta (TGFbeta)-mediated Germ Layer Induction in Xenopus Embryos.
Authors: Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen Y, Zhang M, Tao Q, Wu W
J Biol Chem, 2015-05-26;290(28):17239-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of articular chondrocytes from human pluripotent stem cells.
Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
Nat Biotechnol, 2015-05-11;33(6):638-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells.
Authors: Yang J, Wang W, Ooi J, Campos L, Lu L, Liu P
Stem Cells, 2015-05-01;33(5):1390-404.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease.
Authors: Stayte S, Rentsch P, Li K, Vissel B
PLoS ONE, 2015-04-22;10(4):e0124325.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
J Biol Chem, 2015-04-06;290(21):13053-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression.
Authors: Katano M, Ema M, Nakachi Y, Mizuno Y, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Takahashi S, Okazaki Y, Okuda A
Stem Cells, 2015-04-01;33(4):1089-101.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
Development, 2015-03-26;142(8):1528-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro generation of human pluripotent stem cell derived lung organoids.
Authors: Dye, Briana R, Hill, David R, Ferguson, Michael, Tsai, Yu-Hwai, Nagy, Melinda, Dyal, Rachel, Wells, James M, Mayhew, Christop, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R
Elife, 2015-03-24;4(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Reprogramming of HUVECs into induced pluripotent stem cells (HiPSCs), generation and characterization of HiPSC-derived neurons and astrocytes.
Authors: Haile, Yohannes, Nakhaei-Nejad, Maryam, Boakye, Paul A, Baker, Glen, Smith, Peter A, Murray, Allan G, Giuliani, Fabrizio, Jahroudi, Nadia
PLoS ONE, 2015-03-19;10(3):e0119617.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
Authors: Pezzolla D, Lopez-Beas J, Lachaud C, Dominguez-Rodriguez A, Smani T, Hmadcha A, Soria B
PLoS ONE, 2015-03-16;10(3):e0119904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
Authors: Yoon, Se-Jin, Foley, Joseph W, Baker, Julie C
Nat Commun, 2015-03-16;6(0):6546.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
Authors: Sugawa F, Arauzo-Bravo M, Yoon J, Kim K, Aramaki S, Wu G, Stehling M, Psathaki O, Hubner K, Scholer H
EMBO J, 2015-03-06;34(8):1009-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes.
Authors: Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, Anselmi F, Rapelli S, Grillo M, Borghi S, Oliviero S
Stem Cells, 2015-03-01;33(3):742-50.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
PLoS ONE, 2015-02-23;10(2):e0118670.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcription factor binding dynamics during human ES cell differentiation.
Authors: Tsankov, Alexande, Gu, Hongcang, Akopian, Veronika, Ziller, Michael, Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexande
Nature, 2015-02-19;518(7539):344-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The differential anti-tumour effects of zoledronic acid in breast cancer - evidence for a role of the activin signaling pathway.
Authors: Wilson C, Ottewell P, Coleman R, Holen I
BMC Cancer, 2015-02-14;15(0):55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DMSO efficiently down regulates pluripotency genes in human embryonic stem cells during definitive endoderm derivation and increases the proficiency of hepatic differentiation.
Authors: Czysz, Katherin, Minger, Stephen, Thomas, Nick
PLoS ONE, 2015-02-06;10(2):e0117689.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
Nat Protoc, 2015-02-05;10(3):413-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures.
Authors: Fowler T, Kamalakar A, Akel N, Kurten R, Suva L, Gaddy D
J Cell Sci, 2015-01-20;128(4):683-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.
Authors: Krawchuk D, Anani S, Honma-Yamanaka N, Polito S, Shafik M, Yamanaka Y
J Cell Sci, 2015-01-14;128(5):1011-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Overexpression of activin-A and -B in malignant mesothelioma - attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth.
Authors: Tamminen J, Yin M, Ronty M, Sutinen E, Pasternack A, Ritvos O, Myllarniemi M, Koli K
Exp Cell Res, 2014-12-31;332(1):102-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells.
Authors: Wu J, Fan Y, Tzanakakis E
Stem Cells Dev, 2014-12-22;24(7):892-903.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro.
Authors: Gao W, Zhou P, Ma X, Tschudy-Seney B, Chen J, Magner N, Revzin A, Nolta J, Zern M, Duan Y
PLoS ONE, 2014-11-13;9(11):e112698.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs.
Authors: Wile B, Ban K, Yoon Y, Bao G
Nat Protoc, 2014-09-18;9(10):2411-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection.
Authors: Noguchi, H, Saitoh, I, Tsugata, T, Kataoka, H, Watanabe, M, Noguchi, Y
Cell Death Differ, 2014-09-05;22(1):145-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveals differentially expressed microRNAs and novel IsomiRs with distinct targets.
Authors: Hinton A, Hunter S, Afrikanova I, Jones G, Lopez A, Fogel G, Hayek A, King C
Stem Cells, 2014-09-01;32(9):2360-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
PLoS Biol, 2014-08-26;12(8):e1001937.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity.
Authors: Guo T, Marmol P, Moliner A, Bjornholm M, Zhang C, Shokat K, Ibanez C
Elife, 2014-08-25;3(0):e03245.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Alteration of skin wound healing in keratinocyte-specific mediator complex subunit 1 null mice.
Authors: Noguchi F, Nakajima T, Inui S, Reddy J, Itami S
PLoS ONE, 2014-08-14;9(8):e102271.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells.
Authors: Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, Skerjanc I
Stem Cell Reports, 2014-08-07;3(3):516-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors.
Authors: Mitchell R, Szabo E, Shapovalova Z, Aslostovar L, Makondo K, Bhatia M
Stem Cells, 2014-08-01;32(8):2178-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes.
Authors: Hua X, Wang Y, Tang Y, Yu S, Jin S, Meng X, Li H, Liu F, Sun Q, Wang H, Li J
PLoS ONE, 2014-07-10;9(7):e102198.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes.
Authors: Dambrot C, Braam S, Tertoolen L, Birket M, Atsma D, Mummery C
J Cell Mol Med, 2014-07-01;18(8):1509-18.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways.
Authors: Zhu Q, Song L, Peng G, Sun N, Chen J, Zhang T, Sheng N, Tang W, Qian C, Qiao Y, Tang K, Han J, Li J, Jing N
Elife, 2014-06-14;3(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
Authors: Onishi K, Tonge P, Nagy A, Zandstra P
Stem Cell Reports, 2014-06-06;3(1):156-68.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.
Authors: Liu Y, Kaneda R, Leja T, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz R, Barahona M, Schneider M
Stem Cells, 2014-06-01;32(6):1515-26.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generation of organized germ layers from a single mouse embryonic stem cell.
Authors: Poh Y, Chen J, Hong Y, Yi H, Zhang S, Chen J, Wu D, Wang L, Jia Q, Singh R, Yao W, Tan Y, Tajik A, Tanaka T, Wang N
Nat Commun, 2014-05-30;5(0):4000.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Authors: Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K
Stem Cells Transl Med, 2014-05-29;3(8):911-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer.
Authors: Togashi, Yosuke, Sakamoto, Hiroki, Hayashi, Hidetosh, Terashima, Masato, de Velasco, Marco A, Fujita, Yoshihik, Kodera, Yasuo, Sakai, Kazuko, Tomida, Shuta, Kitano, Masayuki, Ito, Akihiko, Kudo, Masatosh, Nishio, Kazuto
Mol Cancer, 2014-05-27;13(0):126.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro.
Authors: Pethe, Prasad, Nagvenkar, Punam, Bhartiya, Deepa
BMC Cell Biol, 2014-05-24;15(0):18.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nodal.Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation.
Authors: Fuerer C, Nostro M, Constam D
J Biol Chem, 2014-05-05;289(25):17854-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.
Authors: Chong J, Yang X, Don C, Minami E, Liu Y, Weyers J, Mahoney W, Van Biber B, Cook S, Palpant N, Gantz J, Fugate J, Muskheli V, Gough G, Vogel K, Astley C, Hotchkiss C, Baldessari A, Pabon L, Reinecke H, Gill E, Nelson V, Kiem H, Laflamme M, Murry C
Nature, 2014-04-30;510(7504):273-7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche.
Authors: Jorgensen A, Young J, Nielsen J, Joensen U, Toft B, Rajpert-De Meyts E, Loveland K
Br J Cancer, 2014-04-29;110(10):2604-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice.
Authors: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
PLoS ONE, 2014-04-15;9(4):e95329.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo.
Authors: Luo J, Weaver M, Cao B, Dennis J, Van Biber B, Laflamme M, Allen M
Stem Cells Transl Med, 2014-04-15;3(6):734-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.
Authors: Ohnuma, Kiyoshi, Fujiki, Ayaka, Yanagihara, Kana, Tachikawa, Saoko, Hayashi, Yohei, Ito, Yuzuru, Onuma, Yasuko, Chan, Techuan, Michiue, Tatsuo, Furue, Miho K, Asashima, Makoto
Sci Rep, 2014-04-11;4(0):4646.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria.
Authors: Kowno, Megumi, Watanabe-Susaki, Kanako, Ishimine, Hisako, Komazaki, Shinji, Enomoto, Kei, Seki, Yasuhiro, Wang, Ying Yin, Ishigaki, Yohei, Ninomiya, Naoto, Noguchi, Taka-aki, Kokubu, Yuko, Ohnishi, Keigoh, Nakajima, Yoshiro, Kato, Kaoru, Intoh, Atsushi, Takada, Hitomi, Yamakawa, Norio, Wang, Pi-Chao, Asashima, Makoto, Kurisaki, Akira
PLoS ONE, 2014-04-07;9(4):e81552.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors.
Authors: Lippmann E, Estevez-Silva M, Ashton R
Stem Cells, 2014-04-01;32(4):1032-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.
Authors: Watanabe, Hitoshi, Takayama, Kazuo, Inamura, Mitsuru, Tachibana, Masashi, Mimura, Natsumi, Katayama, Kazufumi, Tashiro, Katsuhis, Nagamoto, Yasuhito, Sakurai, Fuminori, Kawabata, Kenji, Furue, Miho Kus, Mizuguchi, Hiroyuki
PLoS ONE, 2014-03-20;9(3):e90791.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin.
Authors: Carrancio S, Markovics J, Wong P, Leisten J, Castiglioni P, Groza M, Raymon H, Heise C, Daniel T, Chopra R, Sung V
Br J Haematol, 2014-03-18;165(6):870-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Signaling by the extracellular matrix protein Reelin promotes granulosa cell proliferation in the chicken follicle.
Authors: Eresheim, Christin, Leeb, Christia, Buchegger, Patricia, Nimpf, Johannes
J Biol Chem, 2014-02-26;289(14):10182-91.
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
BMC Cancer, 2014-02-20;14(0):113.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.
Authors: Hakim F, Kaitsuka T, Raeed J, Wei F, Shiraki N, Akagi T, Yokota T, Kume S, Tomizawa K
J Biol Chem, 2014-02-19;289(14):9623-38.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A single-cell and feeder-free culture system for monkey embryonic stem cells.
Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
PLoS ONE, 2014-02-05;9(2):e88346.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
Authors: Seth A, Ye J, Yu N, Guez F, Bedford D, Neale G, Cordi S, Brindle P, Lemaigre F, Kaestner K, Sosa-Pineda B
Development, 2014-02-01;141(3):538-47.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
Nat Protoc, 2014-01-23;9(2):396-409.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods.
Authors: Araoka, Toshikaz, Mae, Shin-ich, Kurose, Yuko, Uesugi, Motonari, Ohta, Akira, Yamanaka, Shinya, Osafune, Kenji
PLoS ONE, 2014-01-15;9(1):e84881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells.
Authors: Massumi M, Hoveizi E, Baktash P, Hooti A, Ghazizadeh L, Nadri S, Pourasgari F, Hajarizadeh A, Soleimani M, Nabiuni M, Khorramizadeh M
Exp Cell Res, 2014-01-13;322(1):51-61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
J Am Soc Nephrol, 2013-12-19;25(6):1211-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
Cell Stem Cell, 2013-12-12;14(1):53-67.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells.
Authors: Singh A, Chappell J, Trost R, Lin L, Wang T, Tang J, Matlock B, Weller K, Wu H, Zhao S, Jin P, Dalton S
Stem Cell Reports, 2013-12-05;1(6):532-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.
Authors: Fortin J, Boehm U, Weinstein M, Graff J, Bernard D
FASEB J, 2013-12-05;28(3):1474-85.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
Nat Biotechnol, 2013-12-01;32(1):84-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.
Authors: Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei F, Hakim F, Kume S, Tomizawa K
Stem Cells Transl Med, 2013-11-29;3(1):114-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CCAAT/enhancer binding protein-mediated regulation of TGFbeta receptor 2 expression determines the hepatoblast fate decision.
Authors: Takayama K, Kawabata K, Nagamoto Y, Inamura M, Ohashi K, Okuno H, Yamaguchi T, Tashiro K, Sakurai F, Hayakawa T, Okano T, Furue M, Mizuguchi H
Development, 2013-11-27;141(1):91-100.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHbeta gene expression.
Authors: Garrel G, Simon V, Denoyelle C, Ishaq M, Rouch C, Dairou J, Magnan C, Migrenne S, Cruciani-Guglielmacci C, Cohen-Tannoudji J
Endocrinology, 2013-11-18;155(2):592-604.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells.
Authors: Lin P, Hung S, Yang Y, Liao L, Hsieh Y, Yen H, Lu H, Lee M, Chu I, Hwang S
Stem Cells Dev, 2013-11-16;23(4):372-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
Authors: Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, Senyei G, Gordon R, Li R, Akar F, Hajjar R, Hulot J, Costa K
FASEB J, 2013-10-30;28(2):644-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enabling autologous human liver regeneration with differentiated adipocyte stem cells.
Authors: Xu, Dan, Nishimura, Toshihik, Zheng, Ming, Wu, Manhong, Su, Hua, Sato, Noboru, Lee, Gordon, Michie, Sara, Glenn, Jeffrey, Peltz, Gary
Cell Transplant, 2013-10-21;23(12):1573-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.
Authors: Takayama K, Nagamoto Y, Mimura N, Tashiro K, Sakurai F, Tachibana M, Hayakawa T, Kawabata K, Mizuguchi H
Stem Cell Reports, 2013-10-03;1(4):322-35.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
Authors: Navarrete E, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge P, Patlolla B, Lee A, Wu H, Beygui R, Wu S, Robbins R, Bers D, Wu J
Circulation, 2013-09-10;128(11):S3-13.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
Authors: Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes S, De Sutter P
Stem Cells Dev, 2013-08-14;22(23):3141-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
Authors: Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V
Cell Stem Cell, 2013-06-06;12(6):748-60.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.
Authors: Buchholz, David E, Pennington, Britney, Croze, Roxanne, Hinman, Cassidy, Coffey, Peter J, Clegg, Dennis O
Stem Cells Transl Med, 2013-04-18;2(5):384-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA.
Authors: Zhang Q, Sun H, Jiang Y, Ding L, Wu S, Fang T, Yan G, Hu Y
PLoS ONE, 2013-03-20;8(3):e59667.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.
Authors: Hoffman J, Wu C, Merrill B
Development, 2013-03-13;140(8):1665-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Human embryonic stem cells differentiate into functional renal proximal tubular-like cells.
Authors: Narayanan, Karthike, Schumacher, Karl M, Tasnim, Farah, Kandasamy, Karthike, Schumacher, Annegret, Ni, Ming, Gao, Shujun, Gopalan, Began, Zink, Daniele, Ying, Jackie Y
Kidney Int, 2013-02-06;83(4):593-603.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.
Authors: Mae, Shin-Ich, Shono, Akemi, Shiota, Fumihiko, Yasuno, Tetsuhik, Kajiwara, Masatosh, Gotoda-Nishimura, Nanaka, Arai, Sayaka, Sato-Otubo, Aiko, Toyoda, Taro, Takahashi, Kazutosh, Nakayama, Naoki, Cowan, Chad A, Aoi, Takashi, Ogawa, Seishi, McMahon, Andrew P, Yamanaka, Shinya, Osafune, Kenji
Nat Commun, 2013-01-01;4(0):1367.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Production of hepatocyte-like cells from human pluripotent stem cells.
Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
Nat Protoc, 2013-01-01;8(2):430-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.
Authors: White M, Rufaihah A, Liu L, Ghebremariam Y, Ivey K, Cooke J, Srivastava D
Stem Cells, 2013-01-01;31(1):92-103.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
Authors: Brafman D, Phung C, Kumar N, Willert K
Cell Death Differ, 2012-11-16;20(3):369-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
Authors: Sneddon, Julie B, Borowiak, Malgorza, Melton, Douglas
Nature, 2012-10-07;491(7426):765-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
Authors: Pereira P, Dobreva M, Maas E, Cornelis F, Moya I, Umans L, Verfaillie C, Camus A, de Sousa Lopes S, Huylebroeck D, Zwijsen A
Development, 2012-09-01;139(18):3343-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells.
Authors: Sui L, Mfopou J, Geens M, Sermon K, Bouwens L
Biochem Biophys Res Commun, 2012-08-29;426(3):380-5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway.
Authors: Bruce D, Macartney T, Yong W, Shou W, Sapkota G
Cell Signal, 2012-07-07;24(11):1999-2006.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cellular basis of tissue regeneration by omentum.
Authors: Shah S, Lowery E, Braun RK
PLoS ONE, 2012-06-06;7(6):e38368.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model.
Authors: Jeon, Kilsoo, Lim, Hyejin, Kim, Jung-Hyu, Thuan, Nguyen V, Park, Seung Hw, Lim, Yu-Mi, Choi, Hye-Yeon, Lee, Eung-Ryo, Kim, Jin-Hoi, Lee, Myung-Sh, Cho, Ssang-Go
Stem Cells Dev, 2012-06-01;21(14):2642-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

APELIN promotes hematopoiesis from human embryonic stem cells.
Blood, 2012-05-18;119(26):6243-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
Authors: Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S
Stem Cells Dev, 2012-02-29;21(12):2273-87.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
Stem Cells Dev, 2012-02-21;21(12):2312-21.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells.
Authors: Prabakar K, Dominguez-Bendala J, Molano R, Pileggi A, Villate S, Ricordi C, Inverardi L
Cell Transplant, 2011-12-21;21(6):1321-39.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15.
Authors: Mottershead D, Ritter L, Gilchrist R
Mol Hum Reprod, 2011-09-12;18(3):121-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
J. Biol. Chem., 2011-07-07;286(34):30034-46.
Species: Human, Mouse
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance

Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.
Authors: Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR, Rendl M
Stem Cells, 2011-06-01;29(6):964-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
Authors: Spence JR, Mayhew CN, Rankin SA
Nature, 2010-12-12;470(7332):105-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals.
Authors: Zhang Q, Jiang J, Han P, Yuan Q, Zhang J, Zhang X, Xu Y, Cao H, Meng Q, Chen L, Tian T, Wang X, Li P, Hescheler J, Ji G, Ma Y
Cell Res., 2010-11-23;21(4):579-87.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Authors: Klim JR, Li L, Wrighton PJ
Nat. Methods, 2010-11-14;7(12):989-94.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.
Authors: Emre N, Vidal JG, Elia J
PLoS ONE, 2010-08-13;5(8):e12148.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
PLoS ONE, 2010-08-11;5(8):e12101.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture, Differentiation, Differentiation

BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation.
Authors: Tramullas M, Lantero A, Diaz A, Morchon N, Merino D, Villar A, Buscher D, Merino R, Hurle JM, Izpisua-Belmonte JC, Hurle MA
J. Neurosci., 2010-01-27;30(4):1502-11.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
Authors: Chng Z, Teo A, Pedersen RA, Vallier L
Cell Stem Cell, 2010-01-08;6(1):59-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
Authors: Chayosumrit M, Tuch B, Sidhu K
Biomaterials, 2009-10-14;31(3):505-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Scaffold-free human cardiac tissue patch created from embryonic stem cells.
Authors: Stevens KR, Pabon L, Muskheli V
Tissue Eng Part A, 2009-06-01;15(6):1211-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.
Authors: Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P
Dev. Biol., 2009-04-07;330(2):286-304.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA
Cell Stem Cell, 2009-04-03;4(4):348-58.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells: implications for luteolysis.
Authors: Dickinson RE, Stewart AJ, Myers M, Millar RP, Duncan WC
Endocrinology, 2009-02-26;150(6):2873-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
Stem Cells, 2009-02-01;27(2):341-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.
Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V
Blood, 2008-07-29;112(8):3154-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells.
Authors: Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L
J. Biol. Chem., 2008-07-02;283(36):24991-5002.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
Cell Stem Cell, 2008-06-05;2(6):602-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
Nature, 2008-04-23;453(7194):524-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm.
Authors: Shiraki N, Yoshida T, Araki K, Umezawa A, Higuchi Y, Goto H, Kume K, Kume S
Stem Cells, 2008-01-31;26(4):874-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A large-scale proteomic analysis of human embryonic stem cells.
Authors: Schulz TC, Swistowska AM, Liu Y
BMC Genomics, 2007-12-27;8(0):478.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells.
Authors: Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, Park KS, Lee HK
Biochem. Biophys. Res. Commun., 2007-12-04;366(1):129-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
Cell, 2007-11-30;131(5):861-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lrp6 is required for convergent extension during Xenopus gastrulation.
Authors: Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E
Development, 2007-11-01;134(22):4095-106.
Species: Xenopus
Sample Types: Whole Tissue
Applications: Bioassay

Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
Authors: Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J
Arthritis Rheum., 2007-11-01;56(11):3715-25.
Species: Human, Porcine
Sample Types: Whole Cells
Applications: Bioassay

Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.
Authors: Oki S, Hashimoto R, Okui Y, Shen MM, Mekada E, Otani H, Saijoh Y, Hamada H
Development, 2007-10-03;134(21):3893-904.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Predicting evolutionary patterns of mammalian teeth from development.
Authors: Kavanagh KD, Evans AR, Jernvall J
Nature, 2007-09-27;449(7161):427-32.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.
Authors: Wang L, Schulz TC, Sherrer ES, Dauphin DS, Shin S, Nelson AM, Ware CB, Zhan M, Song CZ, Chen X, Brimble SN, McLean A, Galeano MJ, Uhl EW, D'Amour KA, Chesnut JD, Rao MS, Blau CA, Robins AJ
Blood, 2007-08-29;110(12):4111-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases.
Authors: Kupershmidt L, Amit T, Bar-Am O, Youdim MB, Blumenfeld Z
J. Neurochem., 2007-08-06;103(3):962-71.
Species: Human
Sample Types: N/A, Whole Cells
Applications: Bioassay, Western Blot

New cell lines from mouse epiblast share defining features with human embryonic stem cells.
Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
Nature, 2007-06-27;448(7150):196-9.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effect of insulin-like growth factor-binding protein 7 on steroidogenesis in granulosa cells derived from equine chorionic gonadotropin-primed immature rat ovaries.
Authors: Tamura K, Matsushita M, Endo A, Kutsukake M, Kogo H
Biol. Reprod., 2007-05-23;77(3):485-91.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Stem cells derived from human fetal membranes display multilineage differentiation potential.
Authors: Ilancheran S, Michalska A, Peh G, Wallace EM, Pera M, Manuelpillai U
Biol. Reprod., 2007-05-09;77(3):577-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The activin A-follistatin system: potent regulator of human extracellular matrix mineralization.
Authors: Eijken M, Swagemakers S, Koedam M, Steenbergen C, Derkx P, Uitterlinden AG, van der Spek PJ, Visser JA, de Jong FH, Pols HA, van Leeuwen JP
FASEB J., 2007-04-20;21(11):2949-60.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Conditional gene expression in human embryonic stem cells.
Authors: Vallier L, Alexander M, Pedersen R
Stem Cells, 2007-02-22;25(6):1490-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Authors: Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA
Dev. Biol., 2007-01-12;304(2):541-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
Authors: McLean AB, D'Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S
Stem Cells, 2007-01-01;25(1):29-38.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
Authors: Greber B, Lehrach H, Adjaye J
Stem Cells, 2006-10-12;25(2):455-64.
Applications: ELISA (Standard)

The role of the activin system in keloid pathogenesis.
Authors: Mukhopadhyay A, Chan SY, Lim IJ, Phillips DJ, Phan TT
Am. J. Physiol., Cell Physiol., 2006-09-13;292(4):C1331-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
Stem Cells, 2006-05-25;24(9):2014-22.
Species: Primate - Callitrix jacchus (Common Marmoset)
Sample Types: Whole Cells
Applications: Bioassay

Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
Dev. Biol., 2006-04-27;295(2):473-85.
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay

Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
Proc. Natl. Acad. Sci. U.S.A., 2006-04-21;103(18):6907-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The activin-follistatin system and in vitro early follicle development in goats.
Authors: Silva JR, Tharasanit T, Taverne MA, van der Weijden GC, Santos RR, Figueiredo JR, van den Hurk R
J. Endocrinol., 2006-04-01;189(1):113-25.
Species: Goat
Sample Types: Whole Tissue
Applications: Bioassay

Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer.
Authors: Ng RK, Gurdon JB
Proc. Natl. Acad. Sci. U.S.A., 2005-01-31;102(6):1957-62.
Species: Xenopus
Sample Types: Whole Cells
Applications: Bioassay

Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
Authors: Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J
Arthritis Rheum., 2004-08-01;50(8):2521-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.
Authors: Gilchrist RB, Ritter LJ, Cranfield M, Jeffery LA, Amato F, Scott SJ, Myllymaa S, Kaivo-Oja N, Lankinen H, Mottershead DG, Groome NP, Ritvos O
Biol. Reprod., 2004-05-05;71(3):732-9.
Species: Bovine, Mouse
Sample Types: Whole Cells
Applications: Bioassay

hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
Authors: Oren A, Toporik A, Biton S, Almogy N, Eshel D, Bernstein J, Savitsky K, Rotman G
Gene, 2004-04-28;331(0):17-31.
Species: Human
Sample Types:
Applications: Bioassay

Nuclear exclusion of Smad2 is a mechanism leading to loss of competence.
Authors: Grimm OH, 107326, Gurdon JB
Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-beta-induced EMT in human lung adenocarcinoma, 2002-07-01;4(7):519-22.
Species: Xenopus
Sample Types: Whole Cells
Applications: Bioassay

Paracrine regulation of FSH by follistatin in folliculostellate cell-enriched primate pituitary cell cultures.
Authors: Kawakami S, 2019, Fujii Y, Okada Y, Winters SJ
101203, 2002-06-01;143(6):2250-8.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay