Recombinant Mouse IL-12 Protein

Progressively enhancing stemness of adoptively transferred T cells with PI3K? blockade improves metabolism and anti-tumor immunity
Authors: Rangel Rivera, GO;Dwyer, CJ;Knochelmann, HM;Smith, AS;Aksoy, BA;Cole, AC;Wyatt, MM;Kumaresan, S;Thaxton, JE;Lesinski, GB;Paulos, CM;
Cancer research
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

Control of nutrient uptake by IRF4 orchestrates innate immune memory
Authors: Santosa, EK;Kim, H;Rückert, T;Le Luduec, JB;Abbasi, AJ;Wingert, CK;Peters, L;Frost, JN;Hsu, KC;Romagnani, C;Sun, JC;
Nature immunology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD40L modulates CD4+ T cell activation through receptor for activated C kinase 1
Authors: van Os, BW;Vos, WG;Bosmans, LA;van Tiel, CM;Toom, MD;Beckers, L;Admiraal, M;Hoeksema, MA;de Winther, MP;Lutgens, E;
European journal of immunology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system
Authors: Fazazi, MR;Ruda, GF;Brennan, PE;Rangachari, M;
Brain research bulletin
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Phasic regulation of the ATP/P2X7 receptor signaling pathway affects the function of antigen-presenting cells in experimental autoimmune uveitis
Authors: Peng, X;Zhang, Y;Bai, X;Li, X;Zhao, R;
International immunopharmacology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
Authors: KA Read, DM Jones, S Pokhrel, EDS Hales, A Varkey, JA Tuazon, CD Eisele, O Abdouni, A Saadey, MR Leonard, RT Warren, MD Powell, JM Boss, EA Hemann, JS Yount, G Xin, HE Ghoneim, CJ Lio, AG Freud, PL Collins, KJ Oestreich
Nature Communications, 2023-03-24;14(1):1652.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nsun2 coupling with RoRgammat shapes the fate of Th17 cells and promotes colitis
Authors: WL Yang, W Qiu, T Zhang, K Xu, ZJ Gu, Y Zhou, HJ Xu, ZZ Yang, B Shen, YL Zhao, Q Zhou, Y Yang, W Li, PY Yang, YG Yang
Nature Communications, 2023-02-16;14(1):863.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of Skin Inflammatory Responses by Aluminum Adjuvant
Authors: Y Liao, L Sun, M Nie, J Li, X Huang, S Heng, W Zhang, T Xia, Z Guo, Q Zhao, LJ Zhang
Pharmaceutics, 2023-02-08;15(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NR4A1 agonist cytosporone B attenuates neuroinflammation in a mouse model of multiple sclerosis
Authors: HZ Yu, BQ Zhu, L Zhu, S Li, LM Wang
Oncogene, 2022-12-01;17(12):2765-2770.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic drug screen identified IOX1 as an inhibitor of Th17-mediated inflammation through targeting TET2
Authors: X Hu, Y Zou, DA Copland, LP Schewitz-B, Y Li, PJP Lait, M Stimpson, Z Zhang, S Guo, J Liang, T Chen, JJ Li, S Yuan, S Li, P Zhou, Y Liu, AD Dick, X Wen, RWJ Lee, L Wei
EBioMedicine, 2022-11-03;86(0):104333.
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation
Authors: SA Park, YJ Lim, WL Ku, D Zhang, K Cui, LY Tang, C Chia, P Zanvit, Z Chen, W Jin, D Wang, J Xu, O Liu, F Wang, A Cain, N Guo, H Nakatsukas, C Wu, YE Zhang, K Zhao, W Chen
Nature Communications, 2022-10-14;13(1):6069.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Authors: M Hashimoto, K Araki, MA Cardenas, P Li, RR Jadhav, HT Kissick, WH Hudson, DJ McGuire, RC Obeng, A Wieland, J Lee, DT McManus, JL Ross, SJ Im, J Lee, JX Lin, B Hu, EE West, CD Scharer, GJ Freeman, AH Sharpe, SS Ramalingam, A Pellerin, V Teichgräbe, WJ Greenleaf, C Klein, JJ Goronzy, P Umaña, WJ Leonard, KA Smith, R Ahmed
Nature, 2022-09-28;610(7930):173-181.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Circular EZH2-encoded EZH2-92aa mediates immune evasion in glioblastoma via inhibition of surface NKG2D ligands
Authors: J Zhong, X Yang, J Chen, K He, X Gao, X Wu, M Zhang, H Zhou, F Xiao, L An, X Wang, Y Shi, N Zhang
Nature Communications, 2022-08-15;13(1):4795.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

hUC-EVs-ATO reduce the severity of acute GVHD by resetting inflammatory macrophages toward the M2 phenotype
Authors: Y Su, X Sun, X Liu, Q Qu, L Yang, Q Chen, F Liu, Y Li, Q Wang, B Huang, XJ Huang, XH Zhang
Journal of hematology & oncology, 2022-07-21;15(1):99.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects
Authors: R Mary, F Chalmin, T Accogli, M Bruchard, C Hibos, J Melin, C Truntzer, E Limagne, V Derangère, M Thibaudin, E Humblin, R Boidot, S Chevrier, L Arnould, C Richard, Q Klopfenste, A Bernard, Y Urade, JA Harker, L Apetoh, F Ghiringhel, F Végran
Cancer Immunology Research, 2022-07-01;0(0):OF1-OF17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Distinct roles of the meningeal layers in CNS autoimmunity
Authors: A Merlini, M Haberl, J Strau beta, L Hildebrand, N Genc, J Franz, D Chilov, K Alitalo, C Flügel-Koc, C Stadelmann, A Flügel, F Odoardi
Nature Neuroscience, 2022-06-30;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Acetylation licenses Th1 cell polarization to constrain Listeria monocytogenes infection
Authors: YS Zhang, DE Xin, Z Wang, W Peng, Y Zeng, J Liang, M Xu, N Chen, J Zhang, J Yue, M Cao, C Zhang, Y Wang, Z Chang, XM Lu, L Chang, YE Chinn
Cell Death and Differentiation, 2022-05-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
Authors: LEA Damasceno, GCM Cebinelli, MF Fernandes, DC Nascimento, GA Públio, MAR Vinolo, SC Oliveira, T Sparwasser, TM Cunha, FQ Cunha, JC Alves-Filh
Cell Reports, 2022-05-24;39(8):110838.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TH17 cells promote CNS inflammation by sensing danger signals via Mincle
Authors: Q Zhang, W Liu, H Wang, H Zhou, K Bulek, X Chen, CJ Zhang, J Zhao, R Zhang, C Liu, Z Kang, RA Bermel, G Dubyak, DW Abbott, TS Xiao, LE Nagy, X Li
Nature Communications, 2022-05-03;13(1):2406.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
Authors: A Krone, Y Fu, S Schreiber, J Kotrba, L Borde, A Nötzold, C Thurm, J Negele, T Franz, S Stegemann-, J Schreiber, C Garbers, A Shukla, R Geffers, B Schraven, D Reinhold, A Dudeck, A Reinhold, AJ Müller, S Kahlfuss
Scientific Reports, 2022-02-04;12(1):1943.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases
Authors: YH Chen, RH Liu, YZ Cui, A Hettinghou, WY Fu, L Zhang, C Zhang, CJ Liu
Arthritis Research & Therapy, 2022-01-19;24(1):27.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Irgm1 regulates metabolism and function in T cell subsets
Authors: Y Alwarawrah, K Danzaki, AG Nichols, BE Fee, C Bock, G Kucera, LP Hale, GA Taylor, NJ MacIver
Scientific Reports, 2022-01-17;12(1):850.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Epigenetic drug ameliorated type 1 diabetes via decreased generation of Th1 and Th17 subsets and restoration of self-tolerance in CD4+ T cells
Authors: V Patel, A Jayaraman, S Jayaraman
International immunopharmacology, 2021-12-23;103(0):108490.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators
Authors: M Gurusamy, D Tischner, J Shao, S Klatt, S Zukunft, R Bonnavion, S Günther, K Siebenbrod, RI Kestner, T Kuhlmann, I Fleming, S Offermanns, N Wettschure
Nature Communications, 2021-11-23;12(1):6798.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulatory T�cell differentiation is controlled by alphaKG-induced alterations in mitochondrial metabolism and lipid homeostasis
Authors: MI Matias, CS Yong, A Foroushani, C Goldsmith, C Mongellaz, E Sezgin, KR Levental, A Talebi, J Perrault, A Rivière, J Dehairs, O Delos, J Bertand-Mi, JC Portais, M Wong, JC Marie, A Kelekar, S Kinet, VS Zimmermann, I Levental, L Yvan-Charv, JV Swinnen, SA Muljo, H Hernandez-, S Tardito, N Taylor, V Dardalhon
Cell Reports, 2021-11-02;37(5):109911.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease
Authors: L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen
Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
Authors: A Osman, B Yan, Y Li, KD Pavelko, J Quandt, A Saadalla, MP Singh, M Kazemian, F Gounari, K Khazaie
Nature Immunology, 2021-08-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity
Authors: J Zhou, X Zhang, J Hu, R Qu, Z Yu, H Xu, H Chen, L Yan, C Ding, Q Zou, Y Ye, Z Wang, RA Flavell, HB Li
Science Advances, 2021-06-16;7(25):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function
Authors: S Sheppard, EK Santosa, CM Lau, S Violante, P Giovanelli, H Kim, JR Cross, MO Li, JC Sun
Cell Reports, 2021-06-01;35(9):109210.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bruton's tyrosine kinase regulates gut immune homeostasis through attenuating Th1 response
Authors: D Guan, Z Wang, J Huo, S Xu, KP Lam
Cell Death & Disease, 2021-04-30;12(5):431.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Deconvoluting global cytokine signaling networks in natural killer cells
Authors: GM Wiedemann, EK Santosa, S Grassmann, S Sheppard, JB Le Luduec, NM Adams, C Dang, KC Hsu, JC Sun, CM Lau
Nature Immunology, 2021-04-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
Authors: PMIA Doss, M Umair, J Baillargeo, R Fazazi, N Fudge, I Akbar, AP Yeola, JB Williams, M Leclercq, C Joly-Beaup, P Beauchemin, GF Ruda, M Alpaugh, AC Anderson, PE Brennan, A Droit, H Lassmann, CS Moore, M Rangachari
Cell Reports, 2021-03-09;34(10):108833.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases
Authors: A Sripada, K Sirohi, L Michalec, L Guo, JT McKay, S Yadav, M Verma, J Good, D Rollins, MM Gorska, R Alam
PloS Biology, 2021-03-08;19(3):e3001063.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential
Authors: R Contreras-, R Elizondo-V, N Luque-Camp, MJ Torres, C Pradenas, G Tejedor, MJ Paredes-Ma, AM Vega-Lette, M Campos-Mor, Y Rigual-Gon, K Oyarce, M Salgado, C Jorgensen, M Khoury, MLÁ Garcia-Rob, C Altamirano, F Djouad, P Luz-Crawfo
Theranostics, 2021-01-01;11(1):445-460.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells
Authors: GM Wiedemann, S Grassmann, CM Lau, M Rapp, AV Villarino, C Friedrich, G Gasteiger, JJ O'Shea, JC Sun
Cell Reports, 2020-12-15;33(11):108498.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Naringenin Attenuates Experimental Autoimmune Encephalomyelitis by Protecting the Intact of Blood-Brain Barrier and Controlling Inflammatory Cell Migration
Authors: X Niu, H Sang, J Wang
J Nutr Biochem, 2020-11-26;0(0):108560.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
Authors: H Zhang, A Madi, N Yosef, N Chihara, A Awasthi, C Pot, C Lambden, A Srivastava, PR Burkett, J Nyman, E Christian, Y Etminan, A Lee, H Stroh, J Xia, K Karwacz, PI Thakore, N Acharya, A Schnell, C Wang, L Apetoh, O Rozenblatt, AC Anderson, A Regev, VK Kuchroo
Cell Rep, 2020-11-24;33(8):108433.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

The frequency of follicular T helper cells differs in acute and chronic neuroinflammation
Authors: A Baniahmad, K Birkner, J Görg, J Loos, F Zipp, B Wasser, S Bittner
Sci Rep, 2020-11-24;10(1):20485.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Novel Selective Sphingosine Kinase 2 Inhibitor, HWG-35D, Ameliorates the Severity of Imiquimod-Induced Psoriasis Model by Blocking Th17 Differentiation of Na�ve CD4 T Lymphocytes
Authors: SH Shin, HY Kim, HS Yoon, WJ Park, DR Adams, NJ Pyne, S Pyne, JW Park
Int J Mol Sci, 2020-11-08;21(21):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PPP2R2D suppresses interleukin-2 production and regulatory T cell function
Authors: W Pan, A Sharabi, AP Ferretti, Y Zhang, C Burbano, N Yoshida, MG Tsokos, GC Tsokos
JCI Insight, 2020-10-02;5(19):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
Authors: MA Maqbool, L Pioger, AZ El Aabidin, N Karasu, AM Molitor, LTM Dao, G Charbonnie, F van Laethe, R Fenouil, F Koch, G Lacaud, I Gut, M Gut, S Amigorena, O Joffre, T Sexton, S Spicuglia, JC Andrau
Cell Rep, 2020-08-18;32(7):108048.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression
Authors: A Villegas-M, G Khandelwal, LM McGowan, RS Dookie, MJ Haley, C George, D Sims, GM Lord, LV Sinclair, RG Jenner, KN Couper
J. Immunol., 2020-08-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

PPAR&beta/&delta-dependent MSC metabolism determines their immunoregulatory properties
Authors: RA Contreras-, R Elizondo-V, MJ Torres, AM Vega-Lette, N Luque-Camp, MJ Paredes-Ma, C Pradenas, G Tejedor, K Oyarce, M Salgado, C Jorgensen, M Khoury, G Kronke, MA Garcia-Rob, C Altamirano, P Luz-Crawfo, F Djouad
Sci Rep, 2020-07-10;10(1):11423.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
Cell Rep, 2020-06-30;31(13):107820.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal
Authors: MND Svensson, M Zoccheddu, S Yang, G Nygaard, C Secchi, KM Doody, K Slowikowsk, F Mizoguchi, F Humby, R Hands, E Santelli, C Sacchetti, K Wakabayash, DJ Wu, C Barback, R Ai, W Wang, GP Sims, P Mydel, T Kasama, DL Boyle, F Galimi, D Vera, ML Tremblay, S Raychaudhu, MB Brenner, GS Firestein, C Pitzalis, AH Ekwall, SM Stanford, N Bottini
Sci Adv, 2020-06-26;6(26):eaba4353.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation
Authors: Y Liu, R Bockermann, M Hadi, I Safari, B Carrion, M Kveiborg, S Issazadeh-
Cell. Mol. Immunol., 2020-06-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins
Authors: CD Swaim, LA Canadeo, KJ Monte, S Khanna, DJ Lenschow, JM Huibregtse
Cell Rep, 2020-06-16;31(11):107772.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences
Authors: BS Gerstenber, ME Banker, JD Clark, ME Dowty, A Fensome, R Gifford, MC Griffor, M Hegen, BD Hollingshe, JD Knafels, TH Lin, JF Smith, FF Vajdos
Sci Rep, 2020-06-02;10(1):8974.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg
Authors: JS Dolina, J Lee, RQ Griswold, L Labarta-Ba, S Kannan, JA Greenbaum, N Bahia El I, MJ Pont, M Croft, SP Schoenberg
Cell Rep, 2020-04-07;31(1):107249.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
Authors: Z Li, EA Korhonen, A Merlini, J Strauss, E Wihuri, H Nurmi, S Antila, J Paech, U Deutsch, B Engelhardt, S Chintharla, GY Koh, A Flügel, K Alitalo
J. Clin. Invest., 2020-04-01;0(0):.
Species: Mouse
Sample Types: Whole Cell
Applications: Bioassay

TLR4 abrogates the Th1 immune response through IRF1 and IFN-&beta to prevent immunopathology during L. infantum infection
Authors: LA Sacramento, L Benevides, SR Maruyama, L Tavares, KF Fukutani, M Francozo, T Sparwasser, FQ Cunha, RP Almeida, JS da Silva, V Carregaro
PLoS Pathog., 2020-03-25;16(3):e1008435.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Innate T-&alpha&beta lymphocytes as new immunological components of anti-tumoral "off-target" effects of the tyrosine kinase inhibitor dasatinib
Authors: A Barbarin, M Abdallah, L Lefèvre, N Piccirilli, E Cayssials, L Roy, JM Gombert, A Herbelin
Sci Rep, 2020-02-24;10(1):3245.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Loss of NKG2D in murine NK cells leads to increased perforin production upon long-term stimulation with IL-2
Authors: D Prinz, K Klein, J List, VM Knab, I Menzl, N Leidenfros, G Heller, B Poli?, EM Putz, A Witalisz-S, V Sexl, D Gotthardt
Eur. J. Immunol., 2020-02-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells
Authors: S Steinmann, M Schoedsack, F Heinrich, PC Breda, A Ochel, G Tiegs, K Neumann
Sci Rep, 2020-01-23;10(1):1071.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental./hydatid cyst
Authors: M Rahdar, A Rafiei, R Valipour-N
Acta Trop., 2019-10-02;201(0):105206.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation
Authors: C Zhang, BJE Raveney, H Hohjoh, C Tomi, S Oki, T Yamamura
Proc. Natl. Acad. Sci. U.S.A., 2019-09-30;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-12 signaling drives the differentiation and function of a TH1-derived TFH1-like cell population
Authors: MD Powell, KA Read, BK Sreekumar, DM Jones, KJ Oestreich
Sci Rep, 2019-09-30;9(1):13991.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance
Authors: JK Fiege, IA Stone, RE Dumm, BM Waring, BT Fife, J Agudo, BD Brown, NS Heaton, RA Langlois
PLoS Pathog., 2019-09-26;15(9):e1008077.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells
Authors: LP Araujo, JT Maricato, MG Guereschi, MC Takenaka, VM Nascimento, FM de Melo, FJ Quintana, PC Brum, AS Basso
Cell Rep, 2019-09-17;28(12):3120-3130.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

KLF12 Regulates Mouse NK Cell Proliferation
Authors: VC Lam, L Folkersen, OA Aguilar, LL Lanier
J. Immunol., 2019-07-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation
Authors: JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo
J. Leukoc. Biol., 2019-07-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12
Authors: OE Weizman, E Song, NM Adams, AD Hildreth, L Riggan, C Krishna, OA Aguilar, CS Leslie, JR Carlyle, JC Sun, TE O'Sullivan
Nat. Immunol., 2019-07-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death
Authors: K Radulovic, CK Ayata, R Mak'Anyeng, K Lechner, P Wuggenig, B Kaya, P Hruz, M Gomez de A, P Broz, B Weigmann, JH Niess
J. Immunol., 2019-05-31;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Costimulation Induces CD4�T Cell Antitumor Immunity via an Innate-like Mechanism
Authors: C Morales De, JR Maxwell, MM Xu, A Menoret, P Mittal, N Tsurutani, AJ Adler, AT Vella
Cell Rep, 2019-04-30;27(5):1434-1445.e3.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function
Authors: TA Mace, MB Ware, SA King, S Loftus, MR Farren, E McMichael, S Scoville, C Geraghty, G Young, WE Carson, SK Clinton, GB Lesinski
Sci Rep, 2019-03-25;9(1):5068.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection
Authors: P Kumar, K Rajasekara, A Nanbakhsh, J Gorski, MS Thakar, S Malarkanna
Sci Rep, 2019-03-21;9(1):4984.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development
Authors: Y Liu, Y Song, D Lin, L Lei, Y Mei, Z Jin, H Gong, Y Zhu, B Hu, Y Zhang, L Zhao, HY Teo, J Qiu, W Jiang, C Dong, D Wu, Y Huang, H Liu
EBioMedicine, 2019-03-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity
Authors: M Ott, E Avendaño-G, E Ullrich, C Dreyer, J Strauss, M Harden, M Schön, MP Schön, G Bernhardt, C Stadelmann, C Wegner, W Brück, S Nessler
J Neuroinflammation, 2019-02-26;16(1):49.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity
Authors: N Simonovi?, A Witalisz-S, K Meissl, C Lassnig, U Reichart, T Kolbe, M Farlik, C Bock, V Sexl, M Müller, B Strobl
J. Immunol., 2019-02-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis
Authors: KL Graham, BJ Werner, KM Moyer, AK Patton, CR Krois, HS Yoo, M Tverskoy, M LaJevic, JL Napoli, RA Sobel, BA Zabel, EC Butcher
Proc. Natl. Acad. Sci. U.S.A., 2019-02-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
Authors: K Yasuda, Y Kitagawa, R Kawakami, Y Isaka, H Watanabe, G Kondoh, T Kohwi-Shig, S Sakaguchi, K Hirota
Nat Commun, 2019-02-01;10(1):549.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TCR Retrogenic Mice as a Model To Map Self-Tolerance Mechanisms to the Cancer Mucosa Antigen GUCY2C
Authors: TS Abraham, JC Flickinger, SA Waldman, AE Snook
J. Immunol., 2019-01-14;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

REV-ERB? Regulates TH17 Cell Development and Autoimmunity
Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
Cell Rep, 2018-12-26;25(13):3733-3749.e8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance
Authors: J Gilleron, G Bouget, S Ivanov, C Meziat, F Ceppo, B Vergoni, M Djedaini, A Soprani, K Dumas, A Jacquel, L Yvan-Charv, N Venteclef, JF Tanti, M Cormont
Cell Rep, 2018-12-18;25(12):3329-3341.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming
Authors: L Simula, I Pacella, A Colamatteo, C Procaccini, V Cancila, M Bordi, C Tregnago, M Corrado, M Pigazzi, V Barnaba, C Tripodo, G Matarese, S Piconese, S Campello
Cell Rep, 2018-12-11;25(11):3059-3073.e10.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
Authors: AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br
Nat. Med., 2018-11-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections
Authors: IJ Jensen, CS Winborn, MG Fosdick, P Shao, MM Tremblay, Q Shan, SK Tripathy, CM Snyder, HH Xue, TS Griffith, JC Houtman, VP Badovinac
PLoS Pathog., 2018-10-31;14(10):e1007405.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation
Authors: CJ Zhang, M Jiang, H Zhou, W Liu, C Wang, Z Kang, B Han, Q Zhang, X Chen, J Xiao, A Fisher, WJ Kaiser, MA Murayama, Y Iwakura, J Gao, J Carman, A Dongre, G Dubyak, DW Abbott, FD Shi, RM Ransohoff, X Li
J. Clin. Invest., 2018-10-29;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development
Authors: V Jelen?i?, M Šestan, I Kavazovi?, M Lenarti?, S Marinovi?, TD Holmes, M Prchal-Mur, B Lisni?, V Sexl, YT Bryceson, FM Wensveen, B Poli?
Nat. Immunol., 2018-09-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

GLK-IKK? signaling induces dimerization and translocation of the AhR-ROR?t complex in IL-17A induction and autoimmune disease
Authors: HC Chuang, CY Tsai, CH Hsueh, TH Tan
Sci Adv, 2018-09-12;4(9):eaat5401.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection
Authors: CD Geary, C Krishna, CM Lau, NM Adams, SV Gearty, Y Pritykin, AR Thomsen, CS Leslie, JC Sun
Cell Rep, 2018-08-21;24(8):1949-1957.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions
Authors: SK Varanasi, NK Rajasagi, U Jaggi, BT Rouse
Mucosal Immunol, 2018-08-07;0(0):.
Species: Mouse
Sample Types:

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
Authors: M Zhao, MND Svensson, K Venken, A Chawla, S Liang, I Engel, P Mydel, J Day, D Elewaut, N Bottini, M Kronenberg
Nat Commun, 2018-07-06;9(1):2627.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment.
Authors: A Martin, C Seignez, C Racoeur, N Isambert, Isambert N, N Mabrouk, Mabrouk N, A Scagliarin, Scagliarini A, S Reveneau, Reveneau S, L Arnould, Arnould L, A Bettaieb, JF Jeannin, Jeannin J, C Paul
Oncotarget, 2018-06-19;9(47):28364-28378.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs
Authors: OAW Haabeth, M Fauskanger, M Manzke, KU Lundin, A Corthay, B Bogen, AA Tveita
Cancer Res., 2018-05-11;0(0):.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

The localisation of the heparin binding sites of human and murine interleukin-12 within the carboxyterminal domain of the P40 subunit
Authors: P Garnier, R Mummery, MJ Forster, B Mulloy, RV Gibbs, CC Rider
Cytokine, 2018-05-10;110(0):159-168.
Species: Mouse
Sample Types: Complex Sample Type
Applications: Bioassay

The adaptor molecule CD2AP in CD4 T cells modulates differentiation of follicular helper T cells during chronic LCMV infection
Authors: S Raju, K Kometani, T Kurosaki, AS Shaw, T Egawa
PLoS Pathog., 2018-05-07;14(5):e1007053.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A new RelB-dependent CD117+CD172a+murine dendritic cell subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo
Authors: N Andreas, M Riemann, CN Castro, M Groth, I Koliesnik, C Engelmann, T Sparwasser, T Kamradt, R Haenold, F Weih
Eur. J. Immunol., 2018-04-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection
Authors: T Nabekura, Z Chen, C Schroeder, T Park, E Vivier, LL Lanier, D Liu
J. Immunol., 2018-04-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
Immunity, 2018-03-20;48(3):556-569.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Targeting tumor�vasculature�with TNF leads effector T cells to the tumor and enhances therapeutic efficacy of immune checkpoint blockers in combination with ACT
Authors: AR Elia, M Grioni, V Basso, F Curnis, M Freschi, A Corti, A Mondino, M Bellone
Clin. Cancer Res., 2018-02-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Reprograming Immunity to Food Allergens
Authors: AL St John, GWX Ang, APS Rathore, SN Abraham
J. Allergy Clin. Immunol., 2018-02-05;0(0):.
Species: Mouse
Sample Types: Nanoparticles
Applications: In Vivo

P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells
Authors: J Choi, DR Pease, S Chen, B Zhang, H Phee
Immunology, 2018-02-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hexokinase II may be dispensable for CD4 T cell responses against a virus infection
Authors: SK Varanasi, U Jaggi, N Hay, BT Rouse
PLoS ONE, 2018-01-19;13(1):e0191533.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Generating the Abscopal Effect by Combining Proapoptotic Peptides With IL-12-Based Immunotherapy
Authors: F Martins, G Stalder, M Obeid
Neoplasia, 2017-12-26;20(2):193-196.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target.
Authors: Jonas J Staudacher, Cemal Yazici, Timothy Carroll, Jessica Bauer, Jingbo Pang, Nancy Krett, Yinglin Xia, Annette Wilson, Georgios Papachris, Andrea Dirmeier, Claudia Kunst, David C Whitcomb, Giamila Fantuzzi, Barbara Jung
Scientific Reports, 2017-10-06;0(0):2045-2322.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Absence of Notch1 in murine myeloid cells attenuates the development of experimental autoimmune encephalomyelitis by affecting Th1 and Th17 priming
Authors: M Fernández, EM Monsalve, S López-Lópe, A Ruiz-Garcí, S Mellado, E Caminos, JJ García-Ram, J Laborda, P Tranque, MJM Díaz-Guerr
Eur. J. Immunol., 2017-08-31;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells
Authors: KA Read, MD Powell, CE Baker, BK Sreekumar, VM Ringel-Sca, H Bachus, RE Martin, ID Cooley, IC Allen, A Ballestero, KJ Oestreich
J. Immunol., 2017-08-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function
Authors: T Hosokawa, T Kimura, S Nada, T Okuno, D Ito, S Kang, S Nojima, K Yamashita, T Nakatani, Y Hayama, Y Kato, Y Kinehara, M Nishide, N Mikami, S Koyama, H Takamatsu, D Okuzaki, N Ohkura, S Sakaguchi, M Okada, A Kumanogoh
J. Immunol., 2017-08-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects
Authors: SK Varanasi, D Donohoe, U Jaggi, BT Rouse
J. Immunol., 2017-08-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells
Authors: J Chen, JL Martindale, C Cramer, M Gorospe, U Atasoy, PD Drew, S Yu
J. Biol. Chem., 2017-07-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy
Authors: J Ye, Y Wang, X Liu, L Li, A Opejin, EC Hsueh, H Luo, T Wang, D Hawiger, G Peng
J. Immunol., 2017-06-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The frequency of Th17�cells in the small intestine exhibits a day-night variation dependent on circadian clock activity
Authors: HP Thu Le, Y Nakamura, K Oh-Oka, K Ishimaru, S Nakajima, A Nakao
Biochem. Biophys. Res. Commun., 2017-06-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
Authors: B Afzali, J Grönholm, J Vandrovcov, C O'Brien, HW Sun, I Vanderleyd, FP Davis, A Khoder, Y Zhang, AN Hegazy, AV Villarino, IW Palmer, J Kaufman, NR Watts, M Kazemian, O Kamenyeva, J Keith, A Sayed, D Kasperavic, M Mueller, JD Hughes, IJ Fuss, MF Sadiyah, K Montgomery, J McElwee, NP Restifo, W Strober, MA Linterman, PT Wingfield, HH Uhlig, R Roychoudhu, TJ Aitman, P Kelleher, MJ Lenardo, JJ O'Shea, N Cooper, ADJ Laurence
Nat. Immunol., 2017-05-22;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties
Authors: A Van Acker, K Gronke, A Biswas, L Martens, Y Saeys, J Filtjens, S Taveirne, E Van Ammel, T Kerre, P Matthys, T Taghon, B Vandekerck, J Plum, IR Dunay, A Diefenbach, G Leclercq
Cell Rep, 2017-05-16;19(7):1431-1443.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
Authors: J Geng, S Yu, H Zhao, X Sun, X Li, P Wang, X Xiong, L Hong, C Xie, J Gao, Y Shi, J Peng, RL Johnson, N Xiao, L Lu, J Han, D Zhou, L Chen
Nat. Immunol., 2017-05-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis
Authors: ERO Allan, RI Campden, BW Ewanchuk, P Tailor, DR Balce, NT McKenna, CJ Greene, AL Warren, T Reinheckel, RM Yates
J Neuroinflammation, 2017-05-10;14(1):103.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells
Authors: R Singh, T Miao, ALJ Symonds, B Omodho, S Li, P Wang
J. Immunol., 2017-04-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suppression of murine tumor growth through CD8(+) CTLs via activated DEC-205(+) dendritic cells by sequential administration of ?-galactosylceramide in vivo
Authors: H Kogo, M Shimizu, Y Negishi, F Uchida, H Takahashi
Immunology, 2017-04-18;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor
Authors: K Oh-Oka, Y Kojima, K Uchida, K Yoda, K Ishimaru, S Nakajima, J Hemmi, H Kano, Y Fujii-Kuri, R Katoh, H Ito, A Nakao
Cell Mol Gastroenterol Hepatol, 2017-04-11;4(1):135-151.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1
Authors: G Fu, Q Xu, Y Qiu, X Jin, T Xu, S Dong, J Wang, Y Ke, H Hu, X Cao, D Wang, H Cantor, X Gao, L Lu
J. Exp. Med., 2017-04-11;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
Authors: D Daley, VR Mani, N Mohan, N Akkad, A Ochi, DW Heindel, KB Lee, CP Zambirinis, GSB Pandian, S Savadkar, A Torres-Her, S Nayak, D Wang, M Hundeyin, B Diskin, B Aykut, G Werba, RM Barilla, R Rodriguez, S Chang, L Gardner, LK Mahal, B Ueberheide, G Miller
Nat. Med., 2017-04-10;23(5):556-567.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity
Authors: AM Westendorf, K Skibbe, A Adamczyk, J Buer, R Geffers, W Hansen, E Pastille, V Jendrossek
Cell. Physiol. Biochem, 2017-03-08;41(4):1271-1284.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4(+) memory T cells
Authors: BA Szilagyi, J Triebus, C Kressler, M de Almeida, S Tierling, P Durek, M Mardahl, A Szilagyi, S Floess, J Huehn, U Syrbe, J Walter, JK Polansky, A Hamann
Mucosal Immunol, 2017-02-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Armc5 deletion causes developmental defects and compromises T-cell immune responses
Authors: Y Hu, L Lao, J Mao, W Jin, H Luo, T Charpentie, S Qi, J Peng, B Hu, MM Marcinkiew, A Lamarre, J Wu
Nat Commun, 2017-02-07;8(0):13834.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
Proc. Natl. Acad. Sci. U.S.A, 2017-01-09;114(4):E524-E533.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inflammation enhances the vaccination potential of CD40-activated B cells in mice
Eur. J. Immunol., 2016-12-27;0(0):2016.
Species: Mouse
Sample Types: In Vivo

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
Sci Rep, 2016-12-08;6(0):38387.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Immune signatures of protective spleen memory CD8 T cells
Sci Rep, 2016-11-24;6(0):37651.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells
Authors: W Dawicki, C Li, J Town, X Zhang, JR Gordon
J. Allergy Clin. Immunol., 2016-10-26;139(5):1608-1620.e3.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)

Adaptive immunity against gut microbiota enhances apoE-mediated immune regulation and reduces atherosclerosis and western-diet-related inflammation
Sci Rep, 2016-07-07;6(0):29353.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Interleukin-12 inhibits pathological neovascularization in mouse model of oxygen-induced retinopathy
Authors: Yedi Zhou
Sci Rep, 2016-06-17;6(0):28140.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
J. Biol. Chem., 2016-05-23;291(30):15830-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
PLoS ONE, 2016-05-19;11(5):e0155953.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells
Nat Commun, 2016-05-18;7(0):11626.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice
Authors: BW Li, MJ de Bruijn, I Tindemans, M Lukkes, A KleinJan, HC Hoogsteden, RW Hendriks
Eur J Immunol, 2016-05-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-18R?-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness
Authors: P Holmkvist, L Pool, K Hägerbrand, WW Agace, A Rivollier
Eur J Immunol, 2016-05-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2
Authors: U Schulze-To, M Varrin-Doy, K Pekarek, CM Spencer, A Shetty, SA Sagan, BA Cree, RA Sobel, BT Wipke, L Steinman, RH Scannevin, SS Zamvil
Proc Natl Acad Sci USA, 2016-04-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice
Authors: CM Larabee, Y Hu, S Desai, C Georgescu, JD Wren, RC Axtell, SM Plafker
Mol Vis, 2016-04-11;22(0):332-41.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
J Immunol, 2016-04-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease
Proc. Natl. Acad. Sci. U.S.A., 2016-03-08;113(12):3323-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis.
Authors: Lee J, Kannarkat G, Chung J, Joon Lee H, Graham K, Tansey M
J Neuroinflammation, 2016-02-01;13(1):24.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cutting Edge: MicroRNA-223 Regulates Myeloid Dendritic Cell-Driven Th17 Responses in Experimental Autoimmune Encephalomyelitis.
Authors: Ifergan I, Chen S, Zhang B, Miller S
J Immunol, 2016-01-18;196(4):1455-9.
Species: Mouse
Sample Types: In Vivo

NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine.
Authors: Luci C, Bekri S, Bihl F, Pini J, Bourdely P, Nouhen K, Malgogne A, Walzer T, Braud V, Anjuere F
PLoS ONE, 2015-12-02;10(12):e0143224.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
Authors: Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, Ghosh P
Eur J Immunol, 2015-11-19;46(1):212-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification and Analysis of Natural Killer Cells in Murine Nasal Passages.
Authors: Okada K, Sato S, Sato A, Mandelboim O, Yamasoba T, Kiyono H
PLoS ONE, 2015-11-17;10(11):e0142920.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-36gamma is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis.
Authors: Bozoyan L, Dumas A, Patenaude A, Vallieres L
J Neuroinflammation, 2015-09-17;12(0):173.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
J Immunol, 2015-09-09;195(8):3531-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesothelin-specific cell-based vaccine generates antigen-specific immunity and potent antitumor effects by combining with IL-12 immunomodulator.
Authors: Chang M, Chen Y, Chiang Y, Chen T, Tang Y, Chen C, Sun W, Cheng W
Gene Ther, 2015-08-11;23(1):38-49.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Adaptive Immune-like gamma/delta T Lymphocytes Share Many Common Features with Their alpha/beta T Cell Counterparts.
Authors: Lombes A, Durand A, Charvet C, Riviere M, Bonilla N, Auffray C, Lucas B, Martin B
J Immunol, 2015-06-29;195(4):1449-58.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dynamics of Circulating gammadelta T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
Authors: Beck B, Kim H, O'Brien R, Jadus M, Gillespie G, Cloud G, Hoa N, Langford C, Lopez R, Harkins L, Lamb L
PLoS ONE, 2015-05-08;10(5):e0122387.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection.
Authors: Nabekura T, Girard J, Lanier L
J Immunol, 2015-04-29;194(12):5948-52.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
J Immunol, 2015-03-13;194(8):3634-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGF-beta3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses.
Authors: Okamura T, Sumitomo S, Morita K, Iwasaki Y, Inoue M, Nakachi S, Komai T, Shoda H, Miyazaki J, Fujio K, Yamamoto K
Nat Commun, 2015-02-19;6(0):6329.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection.
Authors: Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl A, Siegmund B, Lochner M, Schmitz I
J Immunol, 2015-02-18;194(6):2888-98.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CXCL13 antibody for the treatment of autoimmune disorders.
Authors: Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, Jonason A, Mallow C, Doherty M, Paris M, Smith E, Zauderer M
BMC Immunol, 2015-02-12;16(0):6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge.
Authors: Monin L, Griffiths K, Slight S, Lin Y, Rangel-Moreno J, Khader S
Mucosal Immunol, 2015-01-28;8(5):1099-109.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CRK proteins selectively regulate T cell migration into inflamed tissues.
Authors: Huang, Yanping, Clarke, Fiona, Karimi, Mobin, Roy, Nathan H, Williamson, Edward K, Okumura, Mariko, Mochizuki, Kazuhiro, Chen, Emily J, Park, Tae-Ju, Debes, Gudrun F, Zhang, Yi, Curran, Tom, Kambayashi, Taku, Burkhardt, Janis K
J Clin Invest, 2015-01-26;125(3):1019-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.
Authors: Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan D, Wu C, Rangachari M, Pertel T, Jin H, Ahmed R, Anderson A, Kuchroo V
Nat Commun, 2015-01-23;6(0):6072.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Authors: Haftmann C, Stittrich A, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz G, Riedel R, Siede J, Lehmann K, Weinberger E, Zimmel D, Lauer U, Haupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grun J, Baumgrass R, Matz M, Lohning M, Scheffold A, Wittmann J, Chang H, Rajewsky N, Jack H, Radbruch A, Mashreghi M
Eur J Immunol, 2015-01-22;45(4):1192-205.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4.
Authors: Walsh J, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens J, Gadani S, Hechler D, Golz G, Rosenberger K, Kammertons T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, Fernandez-Castaneda A, Gaultier A, Gold R, Kanneganti T, Nitsch R, Zipp F, Kipnis J
J Clin Invest, 2015-01-20;125(2):699-714.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes.
Authors: Solt L, Banerjee S, Campbell S, Kamenecka T, Burris T
Endocrinology, 2015-01-05;156(3):869-81.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.
Authors: Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S
PLoS ONE, 2014-12-18;9(12):e115198.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.
Authors: Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang O, Cochran A, Vasser M, Fauber B, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick D, Lill J, Ouyang W, Dixit V
Nature, 2014-12-03;518(7539):417-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease.
Authors: Graham K, Zhang J, Lewen S, Burke T, Dang T, Zoudilova M, Sobel R, Butcher E, Zabel B
PLoS ONE, 2014-12-01;9(12):e112925.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cytomegalovirus generates long-lived antigen-specific NK cells with diminished bystander activation to heterologous infection.
Authors: Min-Oo G, Lanier L
J Exp Med, 2014-11-24;211(13):2669-80.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4(+) T-cell function without causing severe combined immunodeficiency.
Authors: Ghonim M, Pyakurel K, Ju J, Rodriguez P, Lammi M, Davis C, Abughazleh M, Mansy M, Naura A, Boulares A
J Allergy Clin Immunol, 2014-10-19;135(2):425-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels.
Authors: Ke F, Zhang L, Liu Z, Liu J, Yan S, Xu Z, Bai J, Zhu H, Lou F, Wang H, Shi Y, Jiang Y, Su B, Wang H
Stem Cells, 2014-10-01;32(10):2799-810.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.
Authors: Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jegou D, Bosch S, Bach J
PLoS ONE, 2014-09-09;9(9):e106153.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.
Authors: Chiba, Shiho, Ikushima, Hiroaki, Ueki, Hiroshi, Yanai, Hideyuki, Kimura, Yoshitak, Hangai, Sho, Nishio, Junko, Negishi, Hideo, Tamura, Tomohiko, Saijo, Shinobu, Iwakura, Yoichiro, Taniguchi, Tadatsug
Elife, 2014-08-22;3(0):e04177.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells.
Authors: Benkhoucha M, Molnarfi N, Dunand-Sauthier I, Merkler D, Schneiter G, Bruscoli S, Riccardi C, Tabata Y, Funakoshi H, Nakamura T, Reith W, Santiago-Raber M, Lalive P
J Immunol, 2014-08-11;193(6):2743-52.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Role of Blimp-1 in programing Th effector cells into IL-10 producers.
Authors: Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
J Exp Med, 2014-07-29;211(9):1807-19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells.
Authors: Bakdash G, Vogelpoel L, Van Capel T, Kapsenberg M, de Jong E
Mucosal Immunol, 2014-07-16;8(2):265-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lnk/Sh2b3 controls the production and function of dendritic cells and regulates the induction of IFN-gamma-producing T cells.
Authors: Mori T, Iwasaki Y, Seki Y, Iseki M, Katayama H, Yamamoto K, Takatsu K, Takaki S
J Immunol, 2014-07-14;193(4):1728-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells.
Authors: Marcais A, Cherfils-Vicini J, Viant C, Degouve S, Viel S, Fenis A, Rabilloud J, Mayol K, Tavares A, Bienvenu J, Gangloff Y, Gilson E, Vivier E, Walzer T
Nat Immunol, 2014-06-29;15(8):749-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dok1 and Dok2 proteins regulate natural killer cell development and function.
Authors: Celis-Gutierrez J, Boyron M, Walzer T, Pandolfi P, Jonjic S, Olive D, Dalod M, Vivier E, Nunes J
EMBO J, 2014-06-24;33(17):1928-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
Authors: Stoolman J, Duncker P, Huber A, Segal B
J Immunol, 2014-06-13;193(2):564-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

miR-20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting RORgammat and STAT3.
Authors: Zhu E, Wang X, Zheng B, Wang Q, Hao J, Chen S, Zhao Q, Zhao L, Wu Z, Yin Z
J Immunol, 2014-05-19;192(12):5599-609.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
Authors: Reynolds C, Chong D, Raynsford E, Quigley K, Kelly D, Llewellyn-Hughes J, Altmann D, Boyton R
BMC Biol, 2014-05-09;12(0):32.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction.
Authors: Bauer, Christia, Kim, Edward Y, Marangoni, Francesc, Carrizosa, Esteban, Claudio, Natalie, Mempel, Thorsten
J Clin Invest, 2014-05-08;124(6):2425-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NADPH oxidase modifies patterns of MHC class II-restricted epitopic repertoires through redox control of antigen processing.
Authors: Allan E, Tailor P, Balce D, Pirzadeh P, McKenna N, Renaux B, Warren A, Jirik F, Yates R
J Immunol, 2014-04-28;192(11):4989-5001.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice.
Authors: Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, Meng L, Sun H, Zhang Y, Guo Y, Hexner E, Zhang Y
J Immunol, 2014-04-23;192(11):5012-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection.
Authors: Beaulieu A, Zawislak C, Nakayama T, Sun J
Nat Immunol, 2014-04-20;15(6):546-53.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions.
Authors: Freeman B, Meyer C, Slifka M
J Virol, 2014-04-16;88(13):7474-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Parent-of-origin effects implicate epigenetic regulation of experimental autoimmune encephalomyelitis and identify imprinted Dlk1 as a novel risk gene.
Authors: Stridh P, Ruhrmann S, Bergman P, Thessen Hedreul M, Flytzani S, Beyeen A, Gillett A, Krivosija N, Ockinger J, Ferguson-Smith A, Jagodic M
PLoS Genet, 2014-03-27;10(3):e1004265.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
Authors: Duong S, Condotta S, Rai D, Martin M, Griffith T, Badovinac V
J Immunol, 2014-03-19;192(8):3618-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
Authors: Sriskantharajah S, Guckel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis P, Stockinger B, O'Garra A, Prinz M, Kollias G, Ley S
J Immunol, 2014-03-17;192(8):3518-29.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Distinct requirements for activation of NKT and NK cells during viral infection.
Authors: Tyznik A, Verma S, Wang Q, Kronenberg M, Benedict C
J Immunol, 2014-03-14;192(8):3676-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effect of methamphetamine on the microglial damage: role of potassium channel Kv1.3.
Authors: Wang J, Qian W, Liu J, Zhao J, Yu P, Jiang L, Zhou J, Gao R, Xiao H
PLoS ONE, 2014-02-12;9(2):e88642.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Astrocytes modulate the polarization of CD4+ T cells to Th1 cells.
Authors: Beurel E, Harrington L, Buchser W, Lemmon V, Jope R
PLoS ONE, 2014-01-28;9(1):e86257.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation.
Authors: Paul D, Ge S, Lemire Y, Jellison E, Serwanski D, Ruddle N, Pachter J
J Neuroinflammation, 2014-01-21;11(0):10.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Islet antigen-specific Th17 cells can induce TNF-alpha-dependent autoimmune diabetes.
Authors: Li C, Mueller E, Bradley L
J Immunol, 2014-01-20;192(4):1425-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transcription factor Runx3 regulates interleukin-15-dependent natural killer cell activation.
Authors: Levanon, Ditsa, Negreanu, Varda, Lotem, Joseph, Bone, Karen Ra, Brenner, Ori, Leshkowitz, Dena, Groner, Yoram
Mol Cell Biol, 2014-01-13;34(6):1158-69.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation.
Authors: Yang C, Li J, Chiu L, Lan J, Chen D, Chuang H, Huang C, Tan T
J Immunol, 2014-01-08;192(4):1547-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity.
Authors: Berezhnoy, Alexey, Castro, Iris, Levay, Agata, Malek, Thomas R, Gilboa, Eli
J Clin Invest, 2014-01-01;124(1):188-97.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
Authors: Terra R, Wang X, Hu Y, Charpentier T, Lamarre A, Zhong M, Sun H, Mao J, Qi S, Luo H, Wu J
PLoS ONE, 2013-12-31;8(12):e82808.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
J Immunol, 2013-12-09;192(1):59-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The inhibitory receptor BTLA controls gammadelta T cell homeostasis and inflammatory responses.
Authors: Bekiaris V, Sedy J, Macauley M, Rhode-Kurnow A, Ware C
Immunity, 2013-12-05;39(6):1082-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging.
Authors: Renkema K, Li G, Wu A, Smithey M, Nikolich-Zugich J
J Immunol, 2013-11-29;192(1):151-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Altered IFN-gamma-mediated immunity and transcriptional expression patterns in N-Ethyl-N-nitrosourea-induced STAT4 mutants confer susceptibility to acute typhoid-like disease.
Authors: Eva M, Yuki K, Dauphinee S, Schwartzentruber J, Pyzik M, Paquet M, Lathrop M, Majewski J, Vidal S, Malo D
J Immunol, 2013-11-27;192(1):259-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-18 expression results in a recombinant vaccinia virus that is highly attenuated and immunogenic.
Authors: Verardi P, Legrand F, Chan K, Peng Y, Jones L, Yilma T
J Interferon Cytokine Res, 2013-10-29;34(3):169-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue.
Authors: Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, Ballantyne C, Wu H
Arterioscler Thromb Vasc Biol, 2013-10-24;34(1):34-43.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses.
Authors: Wang X, Hu Y, Charpentier T, Lamarre A, Qi S, Wu J, Luo H
J Immunol, 2013-10-18;191(11):5420-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.
Authors: Mascanfroni, Ivan D, Yeste, Ada, Vieira, Silvio M, Burns, Evan J, Patel, Bonny, Sloma, Ido, Wu, Yan, Mayo, Lior, Ben-Hamo, Rotem, Efroni, Sol, Kuchroo, Vijay K, Robson, Simon C, Quintana, Francisc
Nat Immunol, 2013-09-01;14(10):1054-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 cells to the tumour.
Authors: Nunez S, Saez J, Fernandez D, Flores-Santibanez F, Alvarez K, Tejon G, Ruiz P, Maldonado P, Hidalgo Y, Manriquez V, Bono M, Rosemblatt M, Sauma D
Immunology, 2013-05-01;139(1):61-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation.
Authors: Yanaba K, Kamata M, Ishiura N, Shibata S, Asano Y, Tada Y, Sugaya M, Kadono T, Tedder T, Sato S
J Leukoc Biol, 2013-04-29;94(4):563-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation and migratory role of P-selectin ligands during intestinal inflammation.
Authors: Hoffmann U, Pink M, Lauer U, Heimesaat M, Winsauer C, Kruglov A, Schlawe K, Leichsenring C, Liesenfeld O, Hamann A, Syrbe U
PLoS ONE, 2013-04-22;8(4):e62055.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.
Authors: Beurel E, Kaidanovich-Beilin O, Yeh W, Song L, Palomo V, Michalek S, Woodgett J, Harrington L, Eldar-Finkelman H, Martinez A, Jope R
J Immunol, 2013-04-19;190(10):5000-11.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.
Authors: Villegas-Mendez A, de Souza J, Lavelle S, Gwyer Findlay E, Shaw T, Van Rooijen N, Saris C, Hunter C, Riley E, Couper K
PLoS Pathog, 2013-04-11;9(4):e1003293.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Bioassay

p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.
Authors: Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H
Arthritis Rheum, 2013-04-01;65(4):949-59.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lymphoid-tissue stromal cells coordinate innate defense to cytomegalovirus.
Authors: Verma S, Wang Q, Chodaczek G, Benedict C
J Virol, 2013-03-27;87(11):6201-10.
Species: Mouse
Sample Types: Serum
Applications: ELISA (Standard)

IL-21 promotes CD8+ CTL activity via the transcription factor T-bet.
Authors: Sutherland A, Joller N, Michaud M, Liu S, Kuchroo V, Grusby M
J Immunol, 2013-03-11;190(8):3977-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function.
Authors: Filtjens, Jessica, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Vanhees, Mandy, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Leclercq, Georges
J Leukoc Biol, 2013-03-08;93(5):699-711.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.
Authors: Knosp C, Schiering C, Spence S, Carroll H, Nel H, Osbourn M, Jackson R, Lyubomska O, Malissen B, Ingram R, Fitzgerald D, Powrie F, Fallon P, Johnston J, Kissenpfennig A
J Immunol, 2013-03-01;190(7):3235-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Galectin-9 functionally impairs natural killer cells in humans and mice.
Authors: Golden-Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen H
J Virol, 2013-02-13;87(9):4835-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
Authors: Bancerek J, Poss Z, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dolken L, Strobl B, Muller M, Taatjes D, Kovarik P
Immunity, 2013-01-24;38(2):250-62.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
Nat Med, 2012-12-02;19(1):57-64.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity.
Authors: Jeyanathan M, Damjanovic D, Shaler C, Lai R, Wortzman M, Yin C, Zganiacz A, Lichty B, Xing Z
Mucosal Immunol, 2012-11-07;6(3):612-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An epigenetic silencing pathway controlling T helper 2 cell lineage commitment.
Authors: Allan RS, Zueva E, Cammas F, Schreiber HA, Masson V, Belz GT, Roche D, Maison C, Quivy JP, Almouzni G, Amigorena S
Nature, 2012-07-12;487(7406):249-53.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.
Nat. Med., 2012-07-08;1248(0):18.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of innate CD8+ T-cell activation mediated by cytokines.
Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function.
Authors: Jin W, Qi S, Luo H
BMC Immunol., 2011-12-19;12(0):68.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression.
Authors: Kashiwada M, Cassel SL, Colgan JD
EMBO J., 2011-04-15;30(10):2071-82.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens.
Authors: DePaolo RW, Abadie V, Tang F
Nature, 2011-02-09;471(7337):220-4.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TIM-3: a novel regulatory molecule of alloimmune activation.
Authors: Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
J. Immunol., 2010-10-18;185(10):5806-19.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
J. Virol., 2010-09-29;84(24):12703-12.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA.
Authors: Perrot I, Deauvieau F, Massacrier C
J. Immunol., 2010-07-16;185(4):2080-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
Authors: Yoshizaki A, Yanaba K, Iwata Y
J. Immunol., 2010-07-12;185(4):2502-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Self-specific CD8+ T cells maintain a semi-naive state following lymphopenia-induced proliferation.
Authors: Johnson LD, Jameson SC
J. Immunol., 2010-04-14;184(10):5604-11.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

T cell Ig domain and mucin domain 1 engagement on invariant NKT cells in the presence of TCR stimulation enhances IL-4 production but inhibits IFN-gamma production.
Authors: Kim HS, Kim HS, Lee CW, Chung DH
J. Immunol., 2010-03-10;184(8):4095-106.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.
Authors: Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ
Nat. Med., 2010-01-10;16(2):191-7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dissociated expression of natural killer 1.1 and T-cell receptor by invariant natural killer T cells after interleukin-12 receptor and T-cell receptor signalling.
Authors: Emoto M, Shimizu T, Koike H, Yoshizawa I, Hurwitz R, Kaufmann SH, Emoto Y
Immunology, 2010-01-01;129(1):62-74.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
Authors: Xi H, Katschke KJ, Helmy KY, Wark PA, Kljavin N, Clark H, Eastham-Anderson J, Shek T, Roose-Girma M, Ghilardi N, van Lookeren Campagne M
J. Exp. Med., 2009-12-28;207(1):7-16, S1-5.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
J. Immunol., 2009-10-19;183(10):6135-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
Nat. Med., 2009-09-20;15(10):1170-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.
Authors: Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grun JR, Lohning M, Radbruch A
Immunity, 2009-05-07;30(5):721-30.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production.
Authors: Bourgeois E, Van LP, Samson M, Diem S, Barra A, Roga S, Gombert JM, Schneider E, Dy M, Gourdy P, Girard JP, Herbelin A
Eur. J. Immunol., 2009-04-01;39(4):1046-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
Proc. Natl. Acad. Sci. U.S.A., 2009-03-16;106(14):5954-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.
Authors: Cui W, Joshi NS, Jiang A, Kaech SM
Vaccine, 2009-02-06;27(15):2177-87.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
J. Exp. Med., 2009-01-12;206(1):69-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Capsular polysaccharide and the O-specific antigen impede antibody binding: a potential obstacle for the successful development of an extraintestinal pathogenic Escherichia coli vaccine.
Authors: Russo TA, Beanan JM, Olson R, MacDonald U, Cope JJ
Vaccine, 2008-11-17;27(3):388-95.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Redox regulation of interleukin-4 signaling.
Authors: Sharma P, Chakraborty R, Wang L, Min B, Tremblay ML, Kawahara T, Lambeth JD, Haque SJ
Immunity, 2008-10-17;29(4):551-64.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells.
Authors: Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N
J. Exp. Med., 2008-10-13;205(11):2643-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Expression of bioactive single-chain murine IL-12 in transgenic plants.
Authors: Liu J, Dolan MC, Reidy M, Cramer CL
J. Interferon Cytokine Res., 2008-06-01;28(0):381-92.
Applications: ELISA (Standard)

Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
Authors: Norman MU, Zbytnuik L, Kubes P
Eur. J. Immunol., 2008-05-01;38(5):1368-80.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice.
Authors: Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K
J. Immunol., 2007-12-15;179(12):8274-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Induction of natural killer cell-dependent antitumor immunity by the Autographa californica multiple nuclear polyhedrosis virus.
Authors: Kitajima M, Abe T, Miyano-Kurosaki N, Taniguchi M, Nakayama T, Takaku H
Mol. Ther., 2007-12-04;16(2):261-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Intranasal interleukin-12 therapy inhibits Mycoplasma pneumoniae clearance and sustains airway obstruction in murine pneumonia.
Authors: Salvatore CM, Fonseca-Aten M, Katz-Gaynor K, Gomez AM, Hardy RD
Infect. Immun., 2007-11-26;76(2):732-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.
Authors: Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A
Nat. Immunol., 2007-11-11;8(12):1372-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production.
Authors: Lalli PN, Strainic MG, Lin F, Medof ME, Heeger PS
J. Immunol., 2007-11-01;179(9):5793-802.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production.
Authors: Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T, Nakanishi K
Proc. Natl. Acad. Sci. U.S.A., 2007-08-31;104(37):14765-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo.
Authors: Alcaide P, King SL, Dimitroff CJ, Lim YC, Fuhlbrigge RC, Luscinskas FW
J. Invest. Dermatol., 2007-03-29;127(8):1964-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.
Authors: Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H
J. Allergy Clin. Immunol., 2007-03-01;119(3):662-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections.
Authors: Nakano N, Nishiyama C, Kanada S, Niwa Y, Shimokawa N, Ushio H, Nishiyama M, Okumura K, Ogawa H
Blood, 2007-02-08;109(11):4846-55.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
J. Immunol., 2006-12-15;177(12):8650-7.
Applications: ELISA (Standard)

Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages.
Authors: Ogawa K, Funaba M, Chen Y, Tsujimoto M
J. Immunol., 2006-11-15;177(10):6787-94.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
Authors: Chiang YM, Chang CL, Chang SL, Yang WC, Shyur LF
J Ethnopharmacol, 2006-10-19;110(3):532-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Exogenous IL-12 suppresses experimental autoimmune encephalomyelitis (EAE) by tuning IL-10 and IL-5 levels in an IFN-gamma-dependent way.
Authors: Berghmans N, Dillen C, Heremans H
J. Neuroimmunol., 2006-06-09;176(1):63-75.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
Authors: Wen H, Hogaboam CM, Gauldie J, Kunkel SL
Am. J. Pathol., 2006-06-01;168(6):1940-50.
Applications: ELISA (Standard)

Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo.
Authors: Chapgier A, Wynn RF, Jouanguy E, Filipe-Santos O, Zhang S, Feinberg J, Hawkins K, Casanova JL, Arkwright PD
J. Immunol., 2006-04-15;176(8):5078-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
J Ethnopharmacol, 2006-03-10;106(3):418-24.
Applications: ELISA (Standard)

Increased sensitivity to Salmonella enterica serovar Typhimurium infection in mice undergoing withdrawal from morphine is associated with suppression of interleukin-12.
Authors: Feng P, Wilson QM, Meissler JJ, Adler MW, Eisenstein TK
Infect. Immun., 2005-12-01;73(12):7953-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
Authors: Costa SK, Yshii LM, Poston RN, Muscara MN, Brain SD
J. Neuroimmunol., 2005-11-02;171(1):99-109.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.
Authors: Harrington, Laurie E, Hatton, Robin D, Mangan, Paul R, Turner, Henriett, Murphy, Theresa, Murphy, Kenneth, Weaver, Casey T
Nat Immunol, 2005-10-02;6(11):1123-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sequential ELISA to profile multiple cytokines from small volumes.
Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
J. Immunol. Methods, 2005-07-01;302(1):172-81.
Applications: ELISA (Standard)

17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.
Authors: Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA
Blood, 2004-05-13;104(5):1404-10.
Applications: ELISA (Standard)

Control of Leishmania major in the absence of Tyk2 kinase.
Authors: Schleicher U, Mattner J, Blos M, Schindler H, Rollinghoff M, Karaghiosoff M, Muller M, Werner-Felmayer G, Bogdan C
Eur. J. Immunol., 2004-02-01;34(2):519-29.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

TCR vaccines against a murine T cell lymphoma: a primary role for antibodies of the IgG2c class in tumor protection.
Authors: Lambert SL, Okada CY, Levy R
J. Immunol., 2004-01-15;172(2):929-36.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1.
Authors: Russell TD, Yan Q, Fan G, Khalifah AP, Bishop DK, Brody SL, Walter MJ
J. Immunol., 2003-12-15;171(12):6866-74.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
J. Immunol., 2003-11-15;171(10):5107-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.
Authors: 107335, O'shea JJ
MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner, 2002-09-04;99(19):12281-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Authors: Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW
J. Immunol., 2002-06-01;168(11):5699-708.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay