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Recombinant Mouse Oncostatin M (OSM) Protein

Catalog #: 495-MO
65 Citations 1 Review Datasheet / COA / SDS

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495-MO-025/CF

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495-MO-025
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Citations (65)
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Recombinant Mouse Oncostatin M (OSM) Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.25‑1 ng/mL.
Source
E. coli-derived mouse Oncostatin M/OSM protein
Ala24-Arg206, with an N-terminal Met
Accession #
P53347.1
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
21 kDa

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495-MO (with carrier)

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495-MO/CF (carrier free)

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Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

495-MO

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 25 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

495-MO/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Oncostatin M/OSM

Oncostatin M (OSM) is a member of a cytokine subfamily that includes IL-6, IL-11, LIF, CNTF, and cardiotrophin-1. These cytokines have overlapping biological functions and shared receptor components. Mouse OSM was cloned and identified as an immediate early gene induced in various myeloid and lymphoid cell lines by a subset of cytokines including IL-2, IL-3, GM-CSF and EPO. The mouse OSM cDNA encodes a 263 amino acid residue precursor protein that shows 48% identity with human OSM. Similar to human OSM, the C-terminal region of mouse OSM contains a highly charged region. Deletion of this C-terminal region appears to be essential for the formation of biologically active mOSM.

The biological activity of human OSM has been shown to be mediated either by the LIF/OSM receptor complex composed of gp130 and LIF R alpha or by a human OSM specific receptor composed of gp130 and OSM R alpha. It remains to be determined if the biological activities of mouse OSM can also be mediated by both receptor complexes in mouse cells.

References
  1. Yoshimura, A. et al. (1996) The EMBO Journal 15:1055.
  2. Ray, P. et al. (1996) Endocrinology 137:1151.
  3. Rose, T.M. and A.G. Bruce (1994) in Guidebook to Cytokines and Their Receptors, N.A. Nicola, editor, Oxford University Press, New York, p. 127.
Entrez Gene IDs
5008 (Human); 18413 (Mouse)
Alternate Names
MGC20461; oncostatin M; oncostatin-M; OSM

Citations for Recombinant Mouse Oncostatin M (OSM) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

65 Citations: Showing 1 - 10
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  1. BASOPHILS ACTIVATE PRURICEPTOR-LIKE VAGAL SENSORY NEURONS
    Authors: Wang, JC;Nikpoor, AR;Crosson, T;Kaufmann, E;Rafei, M;Talbot, S;
    bioRxiv : the preprint server for biology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. The Janus kinase 1 is critical for pancreatic cancer initiation and progression
    Authors: Shrestha, H;Rädler, PD;Dennaoui, R;Wicker, MN;Rajbhandari, N;Sun, Y;Peck, AR;Vistisen, K;Triplett, AA;Beydoun, R;Sterneck, E;Saur, D;Rui, H;Wagner, KU;
    Cell reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis
    Authors: Li, Y;Nie, Y;Yang, X;Liu, Y;Deng, X;Hayashi, Y;Plummer, R;Li, Q;Luo, N;Kasai, T;Okumura, T;Kamishibahara, Y;Komoto, T;Ohkuma, T;Okamoto, S;Isobe, Y;Yamaguchi, K;Furukawa, Y;Taniguchi, H;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
    Authors: Haensel, D;Daniel, B;Gaddam, S;Pan, C;Fabo, T;Bjelajac, J;Jussila, AR;Gonzalez, F;Li, NY;Chen, Y;Hou, J;Patel, T;Aasi, S;Satpathy, AT;Oro, AE;
    Nature communications
    Species: Mouse
    Sample Types: Organoid
    Applications: Cell Culture
  5. EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia
    Authors: Bilgic, SN;Domaniku, A;Toledo, B;Agca, S;Weber, BZC;Arabaci, DH;Ozornek, Z;Lause, P;Thissen, JP;Loumaye, A;Kir, S;
    Nature
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Mechanism of paracrine communications between hepatic progenitor cells and endothelial cells
    Authors: S Lee, R Karns, S Shin
    Cellular Signalling, 2022-08-30;100(0):110458.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  7. Oncostatin M Induces Lipolysis and Suppresses Insulin Response in 3T3-L1 Adipocytes
    Authors: JL Bailey, H Hang, A Boudreau, CM Elks
    International Journal of Molecular Sciences, 2022-04-23;23(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
    Authors: M Valussi, J Besser, K Wystub-Lis, S Zukunft, M Richter, T Kubin, T Boettger, T Braun
    Science Advances, 2021-10-13;7(42):eabi6648.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling
    Authors: PP van Krieke, TS Odermatt, M Borsigova, M Blüher, S Wueest, D Konrad
    Molecular Metabolism, 2021-09-20;0(0):101341.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Kruppel-like factor 15 induces the development of mature hepatocyte-like cells from hepatoblasts
    Authors: K Anzai, K Tsuruya, K Ida, T Kagawa, Y Inagaki, A Kamiya
    Scientific Reports, 2021-09-17;11(1):18551.
    Species: Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo
    Authors: N Tanimizu, N Ichinohe, Y Sasaki, T Itoh, R Sudo, T Yamaguchi, T Katsuda, T Ninomiya, T Tokino, T Ochiya, A Miyajima, T Mitaka
    Nature Communications, 2021-06-07;12(1):3390.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Autophagy Is Required for Hepatic Differentiation of Hepatic Progenitor Cells via Wnt Signaling Pathway
    Authors: J Zeng, Y Jing, Q Wu, J Zeng, L Wei, J Liu
    BioMed Research International, 2021-04-08;2021(0):6627506.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  13. The methylation status of the chemerin promoter region located from -?252 to +?258�bp regulates constitutive but not acute-phase cytokine-inducible chemerin expression levels
    Authors: K Kwiecien, P Brzoza, M Bak, P Majewski, I Skulimowsk, K Bednarczyk, J Cichy, M Kwitniewsk
    Sci Rep, 2020-08-13;10(1):13702.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo, Bioassay
  14. ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity
    Authors: S Alcalá, P Sancho, P Martinelli, D Navarro, C Pedrero, L Martín-Hij, S Valle, J Earl, M Rodríguez-, L Ruiz-Cañas, K Rojas, A Carrato, L García-Ber, MÁ Fernández-, PC Hermann, B Sainz
    Nat Commun, 2020-05-29;11(1):2682.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Bioassay
  15. Interaction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M
    Authors: J Lim, JH Choi, EM Park, YH Choi
    Korean J. Physiol. Pharmacol., 2020-05-01;24(3):203-212.
    Species: Mouse
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  16. Interaction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M
    Authors: J Lim, JH Choi, EM Park, YH Choi
    Korean J. Physiol. Pharmacol., 2020-05-01;24(3):203-212.
    Species: Mouse
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  17. Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition
    Authors: M Oatley, ÖV Bölükbas?, V Svensson, M Shvartsman, K Ganter, K Zirngibl, PV Pavlovich, V Milchevska, V Foteva, KN Natarajan, B Baying, V Benes, KR Patil, SA Teichmann, C Lancrin
    Nat Commun, 2020-01-29;11(1):586.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  18. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies
    Authors: S An, I Raju, B Surenkhuu, JE Kwon, S Gulati, M Karaman, A Pradeep, S Sinha, C Mun, S Jain
    Ocul Surf, 2019-04-06;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  19. Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis
    Authors: J Martínez-F, A Prescott, S van Kaster, DL Pedrioli, I McLean, A Moles, T Reinheckel, V Poli, C Watts
    Nat Commun, 2018-12-17;9(1):5343.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression
    Authors: M Simonneau, E Frouin, V Huguier, C Jermidi, JF Jégou, J Godet, A Barra, I Paris, P Levillain, S Cordier-Di, N Pedretti, FX Bernard, JC Lecron, F Morel, L Favot
    Oncotarget, 2018-11-23;9(92):36457-36473.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Identification of a Novel Bone Marrow Cell-Derived Accelerator of Fibrotic Liver Regeneration Through Mobilization of Hepatic Progenitor Cells in Mice
    Authors: T Yanagawa, H Sumiyoshi, K Higashi, S Nakao, R Higashiyam, H Fukumitsu, K Minakawa, Y Chiba, Y Suzuki, K Sumida, K Saito, A Kamiya, Y Inagaki
    Stem Cells, 2018-10-31;37(1):89-101.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice
    Authors: D van Keulen, MG Pouwer, G Pasterkamp, AJ van Gool, MD Sollewijn, HMG Princen, D Tempel
    PLoS ONE, 2018-10-01;13(10):e0204911.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  23. OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung
    Authors: K Tawara, C Bolin, J Koncinsky, S Kadaba, H Covert, C Sutherland, L Bond, J Kronz, JR Garbow, CL Jorcyk
    Breast Cancer Res., 2018-06-14;20(1):53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M
    Authors: SC Sampath, SC Sampath, ATV Ho, SY Corbel, JD Millstone, J Lamb, J Walker, B Kinzel, C Schmedt, HM Blau
    Nat Commun, 2018-04-18;9(1):1531.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation
    Authors: T Machiyama, T So, Y Okuyama, S Kobayashi, HT Phung, A Asao, H Harigae, N Ishii
    Biochem. Biophys. Res. Commun., 2018-04-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Stat3 mediated alterations in lysosomal membrane protein composition
    Authors: B Lloyd-Lewi, CC Krueger, TJ Sargeant, ME D'Angelo, MJ Deery, R Feret, JA Howard, KS Lilley, CJ Watson
    J. Biol. Chem., 2018-01-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice
    Authors: YY Sin, LL Ballantyne, CR Richmond, CD Funk
    Mol Ther Nucleic Acids, 2017-12-01;10(0):122-130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications
    Authors: F Torossian, B Guerton, A Anginot, KA Alexander, C Desterke, S Soave, HW Tseng, N Arouche, L Boutin, I Kulina, M Salga, B Jose, AR Pettit, D Clay, N Rochet, E Vlachos, G Genet, C Debaud, P Denormandi, F Genet, NA Sims, S Banzet, JP Levesque, JJ Lataillade, MC Le Bousse-
    JCI Insight, 2017-11-02;2(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Pyruvate dehydrogenase complex (PDC) subunits moonlight as interaction partners of phosphorylated STAT5 in adipocytes and adipose tissue
    Authors: AJ Richard, H Hang, JM Stephens
    J. Biol. Chem., 2017-10-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice
    Authors: X Jiang, JS Hawkins, J Lee, CO Lizama, FL Bos, JP Zape, P Ghatpande, Y Peng, J Louie, G Lagna, AC Zovein, A Hata
    Nat Commun, 2017-07-25;8(1):128.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy
    Authors: M Yang, A Arai, N Udagawa, T Hiraga, Z Lijuan, S Ito, T Komori, T Moriishi, K Matsuo, K Shimoda, AH Zahalka, Y Kobayashi, N Takahashi, T Mizoguchi
    Sci Rep, 2017-07-10;7(1):4928.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts via activation of the Hedgehog signalling pathway
    Authors: XR Pan, YY Jing, WT Liu, ZP Han, R Li, Y Yang, JN Zhu, XY Li, PP Li, LX Wei
    Cell Cycle, 2017-05-31;0(0):0.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
    Authors: YY Sin, PR Price, LL Ballantyne, CD Funk
    Sci Rep, 2017-05-31;7(1):2585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors
    Authors: V Kochat, Z Equbal, P Baligar, V Kumar, M Srivastava, A Mukhopadhy
    PLoS ONE, 2017-03-22;12(3):e0173977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Generation of non-viral, transgene-free hepatocyte like cells with piggyBac transposon
    Authors: H Katayama, K Yasuchika, Y Miyauchi, H Kojima, R Yamaoka, T Kawai, E Yukie Yosh, S Ogiso, S Kita, K Yasuda, N Sasaki, K Fukumitsu, J Komori, T Ishii, S Uemoto
    Sci Rep, 2017-03-15;7(0):44498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Progressive induction of hepatocyte progenitor cells in chronically injured liver
    Authors: N Tanimizu, N Ichinohe, M Yamamoto, H Akiyama, Y Nishikawa, T Mitaka
    Sci Rep, 2017-01-04;7(0):39990.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow
    Nat Cell Biol, 2016-09-19;18(10):1078-1089.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate
    Authors: Emma L Rawlins
    Development, 2016-08-30;143(20):3686-3699.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  39. Murine Oncostatin M acts via Leukemia Inhibitory Factor Receptor to phosphorylate STAT3 but not STAT1, an effect that protects bone mass
    J Biol Chem, 2016-08-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Liver Progenitors Isolated from Adult Healthy Mouse Liver Efficiently Differentiate to Functional Hepatocytes In Vitro and Repopulate Liver Tissue
    Stem Cells, 2016-07-13;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Foetal hepatic progenitor cells assume a cholangiocytic cell phenotype during two-dimensional pre-culture
    Authors: Kazuya Anzai
    Sci Rep, 2016-06-23;6(0):28283.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Loss of oncostatin M signaling in adipocytes induces insulin resistance and adipose tissue inflammation in vivo
    Authors: Carrie M Elks
    J Biol Chem, 2016-06-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma
    Authors: Takahiro Kodama
    Proc Natl Acad Sci USA, 2016-05-31;113(24):E3384-93.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
    Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
    J. Biol. Chem., 2016-05-23;291(30):15830-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Janus kinase 1 is essential for inflammatory cytokine signaling and mammary gland remodeling
    Authors: K Sakamoto, BL Wehde, KH Yoo, T Kim, N Rajbhandar, HY Shin, AA Triplett, PD Rädler, F Schuler, A Villunger, K Kang, L Hennighaus, KU Wagner
    Mol Cell Biol, 2016-05-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation
    Eur J Immunol, 2016-05-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Long Term Liver Engraftment of Functional Hepatocytes Obtained from Germline Cell-Derived Pluripotent Stem Cells.
    Authors: Fagoonee S, Famulari E, Silengo L, Tolosano E, Altruda F
    PLoS ONE, 2015-08-31;10(8):e0136762.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia.
    Authors: Seto D, Kandarian S, Jackman R
    J Biol Chem, 2015-06-19;290(32):19976-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation.
    Authors: Goyden J, Tawara K, Hedeen D, Willey J, Oxford J, Jorcyk C
    PLoS ONE, 2015-06-01;10(6):e0127230.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.
    Authors: Meares G, Liu Y, Rajbhandari R, Qin H, Nozell S, Mobley J, Corbett J, Benveniste E
    Mol Cell Biol, 2014-08-11;34(20):3911-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014-07-10;9(7):e101937.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  52. Involvement of hepatic stimulator substance in the regulation of hepatoblast maturation into hepatocytes in vitro.
    Authors: Sun G, Dong L, An W
    Stem Cells Dev, 2014-05-02;23(14):1675-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.
    Authors: Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, Walsh N
    Cytokine, 2014-04-22;68(2):101-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters.
    Authors: Nobuhisa I, Osawa M, Uemura M, Kishikawa Y, Anani M, Harada K, Takagi H, Saito K, Kanai-Azuma M, Kanai Y, Iwama A, Taga T
    Mol Cell Biol, 2014-03-24;34(11):1976-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013-11-27;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Lack of oncostatin M receptor beta leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype.
    Authors: Komori T, Tanaka M, Senba E, Miyajima A, Morikawa Y
    J Biol Chem, 2013-06-11;288(30):21861-75.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  57. Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation.
    Authors: Nicolaidou V, Wong MM, Redpath AN
    PLoS ONE, 2012-07-03;7(7):e39871.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  58. Microarray and Proteomic Analysis of Breast Cancer Cell and Osteoblast Co-cultures: ROLE OF OSTEOBLAST MATRIX METALLOPROTEINASE (MMP)-13 IN BONE METASTASIS.
    Authors: Morrison C, Mancini S, Cipollone J, Kappelhoff R, Roskelley C, Overall C
    J. Biol. Chem., 2011-07-22;286(39):34271-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
    Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
    PLoS ONE, 2010-08-11;5(8):e12101.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  60. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010-03-24;184(0):5263-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  61. Oncostatin M induces dendritic cell maturation and Th1 polarization.
    Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
    Biochem. Biophys. Res. Commun., 2010-03-04;394(2):272-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells.
    Authors: Brounais B, David E, Chipoy C, Trichet V, Ferre V, Charrier C, Duplomb L, Berreur M, Redini F, Heymann D, Blanchard F
    Bone, 2009-01-03;44(5):830-9.
    Applications: Western Blot
  63. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006-12-01;177(11):7665-72.
    Species: Mouse
    Sample Types: In Vivo, N/A
    Applications: ELISA (Standard), In Vivo
  64. Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system.
    Authors: Gard AL, Gavin E, Solodushko V, Pennica D
    Neuroscience, 2004-01-01;127(1):43-52.
    Applications: Western Blot
  65. The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
    Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
    Arch. Dermatol. Res., 2001-11-01;293(10):508-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

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Recombinant Mouse Oncostatin M (OSM) Protein
By Kimberly Ng on 08/03/2016
Application: Stem/Immune cell maintenance or differentiation