Recombinant Rat BOK Western Blot Standard Protein

Recombinant Rat BOK Western Blot Standard Protein Summary

Product Specifications

Product Datasheets

Carrier Free

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

Background: BOK

BOK (Bcl-2-related Ovarian Killer) is a 23-kDa pro-apoptotic member of the Bcl-2 family of proteins. BOK has three conserved Bcl-2 homology domains (BH1, 2, and 3) and a C-terminal transmembrane domain, but does not contain the anti-apoptotic BH4 domain. BOK interacts strongly with some anti-apoptotic Bcl-2 proteins (Mcl-1, BHRF1, and A1) and not at all with pro-apoptotic Bcl-2 proteins. The tissue distribution of BOK is restricted to reproductive tissues and it is highly expressed in ovary, testis, and uterus.

Related Research Areas

• Bcl-2 Proteins and Regulators