RETF-4NA
Biological Activity
RETF-4NA is a chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.Technical Data
(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity.
Raymond et al.
J.Immunol., 2009;182:5770
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