RuBi-4AP

Catalog #: 3557 Datasheet / COA / SDS

Discontinued Product

3557 has been discontinued.
View all Voltage-gated Potassium Channel Blockers products.
RuBi-4AP | CAS No. 851956-02-0 | Voltage-gated Potassium Channel Blockers
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Description: Caged 4-aminopyridine; a non-selective KV channel blocker
Alternative Names: Rubi-4-aminopyridine

Chemical Name: bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex

Product Details
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Biological Activity

Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.

Technical Data

M.Wt:
672.58
Formula:
C30H28Cl2N8Ru
Solubility:
Soluble to 30 mM in water
Storage:
Store at -20°C
CAS No:
851956-02-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from Columbia University

Background References

  1. A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage.
    Zayat et al.
    J.Am.Chem.Soc., 2003;125:882
  2. Two-photon uncaging of neurochemicals using inorganic metal complexes.
    Nikolenko et al.
    Chem.Commun., 2005;13:1752

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