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Salbutamol hemisulfate

Catalog #: 0634
6 Citations Datasheet / COA / SDS
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0634/250
Salbutamol hemisulfate | CAS No. 51022-70-9 | Adrenergic beta-2 Receptor Agonists
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Description: β2-adrenoceptor agonist
Alternative Names: Albuterol

Chemical Name: α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate

Purity: ≥98%

Product Details
Citations (6)
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Biological Activity

Salbutamol hemisulfate is a selective β2-adrenergic agonist with 29-fold higher selectivity for β2 over β1 receptors. Salbutamol elevates fibroblast growth factor 20 (FGF20) in nigrostriatal neurons, and is neuroprotective in a mouse model of Parkinson's disease.

Technical Data

M.Wt:
288.35
Formula:
C13H21NO3.½H2SO4
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Store at RT
CAS No:
51022-70-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy
    JM Cruz, N Hupper, LS Wilson, JB Concannon, Y Wang, B Oberhauser, K Patora-Kom, Y Zhang, DJ Glass, AU Trendelenb, BA Clarke
    J. Biol. Chem., 2018;0(0):.
  2. Salmeterol-induced desensitisation, internalization and phosphorylation of the human β2-adrenoceptor.
    January et al.
    Br.J.Pharmacol., 1998;123:701
  3. Effects of the enantiomers of R,S-salbutamol on incompletely fused tetanic contractions of slow- and fast-twitch skeletal muscles of the guinea-pig.
    Prior et al.
    Br.J.Pharmacol., 1998;123:558
  4. Function and regulation of the β3-adrenoceptor.
    Strosberg and Pietri-Rouxel
    TiPS, 1996;17:373

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Citations for Salbutamol hemisulfate

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