Simple Plex Control for Human/Mouse/Rat beta-Synuclein

Catalog #: 897123 Datasheet / COA / SDS

Control for use with Human/Mouse/Rat beta-Synuclein Simple Plex Assay Cartridge Kit

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897123

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Simple Plex Control for Human/Mouse/Rat beta-Synuclein Summary

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human beta-Synuclein concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Specifications

Source

N/A

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Applications

Simple Plex Automated Immunoassay

Species

Human Mouse Rat

Product Datasheets

Product Datasheet

Background: beta-Synuclein

The synuclein family includes alpha-Synuclein, beta-Synuclein, gamma-Synuclein, and synoretin. These small, highly conserved proteins are localized predominantly in the brain, concentrated in presynaptic nerve terminals. Alpha-Synuclein is normally a soluble protein. Abnormal alpha-synuclein forms filamentous inclusions (Lewy bodies and Lewy neurites) in several neurodegenerative diseases, including Parkinson's disease (PD), dementia with Lewy bodies, and Alzheimer's disease. Beta-Synuclein and gamma-Synuclein (synoretin) associate with alpha-synuclein and inhibit its aggregation.

Entrez Gene IDs

6620 (Human); 104069 (Mouse); 113893 (Rat)

Alternate Names

beta-Synuclein; SNCB; synuclein, beta; Synuclein-beta