Simple Plex Control for Human Osteoprotegerin/TNFRSF11B

Catalog #: 898209 Datasheet / COA / SDS

Control for use with Human Osteoprotegerin/TNFRSF11B Simple Plex Cartridge Kit

Catalog #	Availability	Size / Price	Qty
898209

1 Image

All Osteoprotegerin/TNFRSF11B Simple Plex Assays

Product Details

Supplemental Products

Reviews

Summary Product Datasheets Data Images Background

Simple Plex Control for Human Osteoprotegerin/TNFRSF11B Summary

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Osteoprotegerin/TNFRSF11B concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Specifications

Source

N/A

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Applications

Control Simple Plex Automated Immunoassay

Species

Human

Product Datasheets

Product Datasheet

Background: Osteoprotegerin/TNFRSF11B

Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.

Entrez Gene IDs

4982 (Human); 18383 (Mouse)

Alternate Names

OCIF; OCIFMGC29565; OPG; OPGtumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily, member 11b