Simple Plex Human CXCL13/BLC/BCA-1 Cartridge
Simple Plex Human CXCL13/BLC/BCA-1 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay’s minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Product Summary
Precision
Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||
---|---|---|---|---|
Sample | 1 | 2 | 1 | 2 |
n | 16 | 16 | 14 | 13 |
Mean (pg/mL) | 41 | 1797 | 38.6 | 1772 |
Standard Deviation | 1.4 | 102 | 2.41 | 85.6 |
CV% | 3.4 | 5.7 | 6.2 | 4.8 |
Recovery
Recovery at three different spiked concentrations within the range of the assay was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
EDTA Plasma (n=4) | 83 | 76-87 |
Heparin Plasma (n=4) | 78 | 76-83 |
Serum (n=4) | 81 | 77-84 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: CXCL13/BLC/BCA-1
CXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It can form homodimers or heterodimers with FGF basic, and it signals through CXCR3 or CXCR5. CXCL13 induces the migration of naïve B cells and a subset of memory T cells to lymphoid tissue. It also promotes B1 cell migration into the omentum and peritoneum. In the fetus, CXCL13 attracts CD4+ CD3- IL-7 R alpha+ hematopoietic cells to sites of future Peyer’s patch development.
FAQs
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