SKF 81297 hydrobromide
Tocris Bioscience | Catalog # 1447
Product Description
SKF 81297 hydrobromide is a dopamine D1-like receptor agonist. Centrally active following systemic administration in vivo.
Product Specifications for SKF 81297 hydrobromide
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.71 | 10 with gentle warming | |
| DMSO | 37.07 | 100 |
Preparing Stock Solutions for SKF 81297 hydrobromide
The following data is based on the product molecular weight 370.67.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.70 mL | 13.49 mL | 26.98 mL |
| 5 mM | 0.54 mL | 2.70 mL | 5.40 mL |
| 10 mM | 0.27 mL | 1.35 mL | 2.70 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.54 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 67 publications citing the usage of this product.
- Peacock The effects of DA D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment. Eur.J.Pharmacol. 1990 PMID: 1980891
- Reavill Pharmacological characterization of the discriminative stimulus properties of the DA D1 agonist, SKF 81297. Behav.Pharmacol. 1993 PMID: 11224180
- Arnt Relative DA D1 and D2 receptor affinity and efficacy determine whether DA agonists induce hyperactivity or oral stereotypy in rats. Pharmacol.Toxicol. 1988 PMID: 3259694
Product Documents for SKF 81297 hydrobromide
Product Specific Notices for SKF 81297 hydrobromide
For research use only
Citations for SKF 81297 hydrobromide
Customer Reviews for SKF 81297 hydrobromide (1)
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Species: HumanAssay Type: In VitroVerified Customer | Posted 01/04/2018It is very easy to dissolve the productWe used SKF81297 at a concentration of 10 µM/L to active dopamine D1 receptor in cultured mouse striatal neuron.
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