SP 10

Catalog #: 7322 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
7322/1

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Description: Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction

Purity: ≥95%

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

SP 10 is a peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC₅₀ = 1.88 nM in biochemical assay). Inhibits interaction of SARS-CoV S protein and Vero E6 cells in vitro.

Please note, this peptide displays 80% sequence identity to homologous site on SARS-CoV-2 S-protein (residues 689-697).

Technical Data

M.Wt:

1315.5

Formula:

C₅₆H₉₄N₁₄O₂₀S

Sequence:

STSQKSIVAYTM

Solubility:

Soluble to 1 mg/ml in water

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

882157-88-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Design and biological activities of novel inhibitory peptides for SARS-CoV spike protein and angiotensin-converting enzyme 2 interaction.
Ho et al.
Antiviral Res., 2006;69:70

Product Datasheets

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M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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