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SPT Imidazopyridine 1

Catalog #: 6055 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6055/50
6055/10
SPT Imidazopyridine 1 | CAS No. 1933533-18-6 | Other Transferase Inhibitors
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Description: Potent serine palmitoyl transferase inhibitor

Chemical Name: 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid

Purity: ≥98%

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Biological Activity

SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM). Dose-dependently inhibits incorporation of 14C-serine into ceramide. Reduces plasma ceramide levels in vivo. Also increases plasma HDL and reduces vLDL cholesterol levels in rats.

Technical Data

M.Wt:
364.44
Formula:
C22H24N2O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1933533-18-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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