st-Ht31

Catalog #: 6286
2 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
6286/1

1 Image

Description: Inhibits PKA/AKAP interactions; cell permeable

Purity: ≥95%

View All Products for AKAP Inhibitors

Product Details

Citations (2)

Reviews

Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

st-Ht31 is a stearated form of the peptide Ht-31. Inhibits the interaction between the RII subunits of cAMP-dependent PKA and A-kinase anchoring protein (AKAP) in cell extracts. Cell permeable.

Technical Data

M.Wt:

2798.27

Formula:

C₁₂₉H₂₁₇N₂₉O₃₉

Sequence:

DLIEEAASRIVDAVIEQVKAAGAY

(Modifications: Asp-1 = N-terminal Ste)

Solubility:

Soluble to 1 mg/ml in 0.01M PBS (pH 7.4)

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

188425-80-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Negative Control Available

Background References

AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons.
Gorshkov K, Mehta S, Ramamurthy S et al.
Nat. Chem. Biol.
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
Vijayaraghavan et al.
J.Biol.Chem., 1997;272:4747
Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain.
Carr et al.
J.Biol.Chem., 1992;267:13376
Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm.
Stival et al.
J.Biol.Chem., 2018;293:9435

Product Datasheets

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SDS

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Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for st-Ht31

The citations listed below are publications that use Tocris products. Selected citations for st-Ht31 include:

2 Citations: Showing 1 - 2

Mislocalization of protein kinase A drives pathology in Cushing's syndrome.
Authors: G Stanley Et al.
Cell Rep 2022;40:111073
TGFβ1 Induces Axonal Outgrowth via ALK5/PKA/SMURF1-Mediated Degradation of RhoA and Stabilization of PAR6.
Authors: Martin E Et al.
Eneuro 2020;7

FAQs

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