Surfen
Chemical Name: N,N'-Bis(4-amino-2-methyl-6-quinolinyl)urea dihydrochloride
Purity: ≥98%
Biological Activity
Surfen is a heparan sulfate antagonist. Inhibits heparan sulfate-mediated cell attachment in vitro. Maintains hESCs in a pluripotent state by reversible inhibition of glycan-growth factor interactions.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Surfen, a small molecule antagonist of heparan sulfate.
Schuksz et al.
Proc.Natl.Acad.Sci.USA, 2008;105:13074 -
Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state.
Huang et al.
Stem Cells., 2018;36:45
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