Tafluprost
Chemical Name: 1-Methylethyl (5-Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate
Purity: ≥95%
Biological Activity
Tafluprost is a very high affinity FP receptor agonist (Ki = 0.4 nM). Reduces intraocular pressure (IOP) in animal models of ocular hypertension and normal animals.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug.
Takagi et al.
Exp.Eye Res., 2004;78:767
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