Home / Heme Oxygenase Inhibitors / Tin protoporphyrin IX dichloride

Tin protoporphyrin IX dichloride

Catalog #: 0747
3 Citations Datasheet / COA / SDS

Discontinued Product

0747 has been discontinued.
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Tin protoporphyrin IX dichloride | CAS No. 14325-05-4 | Heme Oxygenase Inhibitors
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Description: Heme oxygenase inhibitor
Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Tin protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.

Technical Data

M.Wt:
750.25
Formula:
C34H32Cl2N4O4Sn
Solubility:
Soluble to 5 mM in DMSO
Storage:
Store at RT
CAS No:
14325-05-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling.
    Al-Huseini L, Aw Yeang H, Sethu S, Alhumeed N, Hamdam J, Tingle Y, Djouhri L, Kitteringham N, Park B, Goldring C, Sathish J
    J Biol Chem, 2013;288(31):22281-8.
  2. Subset characterization of myeloid-derived suppressor cells arising during induction of BM chimerism in mice.
    Luyckx A, Schouppe E, Rutgeerts O, Lenaerts C, Koks C, Fevery S, Devos T, Dierickx D, Waer M, Van Ginderachter JA, Billiau AD
    Bone Marrow Transplant., 2012;47(7):985-92.
  3. Pitfalls using metalloporphyrins in carbon monoxide research.
    Grundemar and Ny
    TiPS, 1997;18:193
  4. Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of haem oxidation.
    Drummond and Kappas
    Proc.Natl.Acad.Sci.U.S.A., 1981;78:6466

Product Datasheets

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Citations for Tin protoporphyrin IX dichloride

The citations listed below are publications that use Tocris products. Selected citations for Tin protoporphyrin IX dichloride include:

3 Citations: Showing 1 - 3

  1. Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes.
    Authors: Duann Et al.
    Data Brief  2019;22:279
  2. Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis.
    Authors: Ye Et al.
    BMC Neurosci  2013;13:156
  3. Mitochondrial uncouplers inhibit hepatic stellate cell activation.
    Authors: Guimarães Et al.
    BMC Gastroenterol  2012;12:68

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