TLQP 21
Tocris Bioscience | Catalog # 3051
VGF-derived peptide
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Product Description
TLQP 21 is a VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.
Product Specifications for TLQP 21
Molecular Weight
2432.77
Formula
C107H170N40O26
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
869988-94-3
PubChem ID
16158480
InChI Key
PWWMOXVVMRPYJS-IWCKOKPFSA-N
SMILES
[H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.
- Bartolomucci TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA
- Jethwa VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol.
- Severini TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 2008 PMID: 18173805
Product Documents for TLQP 21
Product Specific Notices for TLQP 21
For research use only
Related Research Areas
Citations for TLQP 21
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