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VH 032 amide-PEG2-acid

Catalog #: 7214 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7214/25
VH 032 amide-PEG2-acid | CAS No. 2172820-09-4 | Degrader Building Blocks
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Description: VHL ligand with PEG linker and terminal acid for onward chemistry
Alternative Names: (S,R,S)-AHPC-PEG2-COOH

Chemical Name: 3-(2-(3-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)ethoxy)propanoic acid

Purity: ≥95%

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Biological Activity

VH 032 amide-PEG2-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
618.75
Formula:
C30H42N4O8S
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2172820-09-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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