Virodhamine trifluoroacetate
Discontinued Product
Chemical Name: O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoate trifluoroacetate
Purity: ≥98%
Biological Activity
Virodhamine trifluoroacetate is a TFA salt of virodhamine, an endogenous cannabinoid receptor mixed agonist/antagonist that is found in higher concentrations peripherally than anandamide. Virodhamine is a full agonist at GPR55 and CB2 and partial agonist/antagonist at CB1 (EC50 values are 12, 381 and 2920 nM at GPR55, CB2 and CB1 receptors respectively).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor.
Porter et al.
J.Pharmacol.Exp.Ther., 2002;301:1020
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Citation for Virodhamine trifluoroacetate
The citations listed below are publications that use Tocris products. Selected citations for Virodhamine trifluoroacetate include:
1 Citation: Showing 1 - 1
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Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors.
Authors: Hayase
BMC Neurosci 2013;14:20
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