XCC
Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity: ≥98%
Biological Activity
XCC is an adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain.
Jarvis et al.
Brain Res., 1989;484:111 -
The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines.
Sebastiao et al.
Br.J.Pharmacol., 1990;101:453 -
Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.
Thummler and Dunwiddie
J.Neurophysiol., 2000;83:1787
Product Datasheets
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Citation for XCC
The citations listed below are publications that use Tocris products. Selected citations for XCC include:
1 Citation: Showing 1 - 1
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An Adenosine Receptor for Olfaction in Fish.
Authors: Wakisaka Et al.
Curr Biol 2017;27:1437
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