This brochure briefly summarizes what is currently known about the cytokines belonging to the common cytokine receptor gamma-chain family, which includes IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. It provides a brief overview of the signaling pathways that are activated in response to each of these cytokines and a description of the primary biological effects that they induce. Additionally, it describes the tools that we offer for research on this cytokine family including:
- Our wide selection of recombinant protein products
- Antibodies validated for a range of applications including blocking or neutralization, flow cytometry, immunohistochemistry, and/or Western blot for both the cytokines and receptors in this family
- Antibodies for detecting the intracellular signaling molecules that are activated in response to these cytokines
- Our selection of gold standard ELISA Kits for these detecting these cytokines
- The Proteome Profiler™ Antibody Arrays that may be relevant for studying the effects of the common cytokine receptor gamma-chain family cytokines
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