P-Selectin/CD62P: Products
P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-Selectin mediates the initial interaction of circulating leukocytes with activated endothelial cells that produce a characteristic ‘rolling’ of the leukocytes on the endothelium. It is therefore critical for leukocyte extravasation at sites of inflammation and leukocyte involvement in thrombus formation at sites of vascular injury.
Products:
- Primary Antibodies
- Proteins & Enzymes
- ELISAs
- Simple Plex Assays
- cDNA Clones
- Luminex Assays
- Proteome Profiler Antibody Arrays
- Small Molecules
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"P-Selectin/CD62P" has 5 results in Products.
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Simple Plex Mouse P-Selectin Cartridge
Simple Plex Mouse P-Selectin/CD62P assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
Simple Plex Control for Human P-Selectin/CD62P
Control for use with Human and Non-Human Primate P-Selectin/CD62P Simple Plex Assay Cartridge Kit
Simple Plex Control for Mouse P-Selectin
Control for use with Mouse P-Selectin Simple Plex Assay Cartridge Kit
Non-Human Primate P-Selectin/CD62P Cartridge
Simple Plex Non-Human Primate P-Selectin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Simple Plex Human P-Selectin/CD62P Assay Cartridge
Simple Plex Human P-Selectin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
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