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Current and Emerging Immune Checkpoint Targets for Immuno-Oncology Research eBook

Learn about some of the current and emerging immune checkpoint molecules that are being investigated as potential targets for cancer immunotherapy.

Angiogenesis	Apotosis
Autophagy	Breast Cancer
Cancer Biomarkers	Cancers of the Blood
Cancer Stem Cells	Cell Motility & Metastases
Cellular Reponse to Stress	Colorectal Cancer
DNA Repair	Epigenetics
Epithelial to Mesencvhymal Transition	Genotoxic Stress Rsp/Reg Cell Cyc Ckpts
Hypoxia	Lung Cancer
Oncogenesis & Tumor Suppressors	Prostate Cancer
Receptor Tyrosine Kinases	Tumor Immunology
Unfolded Protein Response

Angiogenesis	Arhythmias
Atherosclerosis (Coronary & Peripheral)	Biomarkes for Coronary Heart Disease
Cardiomyopathy	Heart Failure
Hypertension	Ischemia/Reperfusion Injury
Myocardial Infarction	Thrombosis & Haemostasis

Adipocytokines	Chemokines
Common Beta-Chain Receptor Family	Common Gamma-Chain Receptor Family
DSL/Notch Family	EGF Family
FGF Family	Hedgehog Family
IL-10/Interferon Family	IL-12 Family
IL-17 Family	IL-1 Family
IL-6 Family	Insulin/GF Familly
Other Interleukins	PDGF Family
TGF-Beta Superfamily	VEGF Family
Wnt Family

Embryonic Patterning & Axis Formation	Gametes & Fertilization
Gastrulation & Germ Layer Formation	Morphogenesis
Organogenesis	Primordial & Mature Germ Cells
Tissue Regeneration

Appetite & Digestion	Bone Growth & Calcium Homeostasis
Cardiovascular & Renal Endocrinology	Diabetes
Hormones & Receptors	Metabolism
Neuroendocrinology	Reproductive Endocrinology

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Carbohydrate Sulfotransferases	Glycosidases
Glycosyltransferases	Protein Sulfotransferases
Proteglycans	Sialytransferases
Sulfatases

Antigen Processing & Presentation	Asthma & Allergic Responses
Autoimmune Disease	B Cells/Antibody Production
Dendritic Cells	Hematopoiesis
Inflammation & Cellular Migration	Innate Immune Response
Musocal Immunity	Natural Killer Cells
Pathogen Recognition Receptors	Pattern Recognition Receptors
T Cell Differentiation & Function	Tumor Immunology
Vaccine Development	Viral Immunology

Addiction	Blood Brain Barrier
Depression	Gila
Ion Channels	Nervous System Development
Neural Stem Cells	Neurodegenerative Disease
Neuroinflammation	Neurotransmitter Transporters
Neurotrophic Factors & Receptors	Nociception
Pain	Sleep
Stress & Anxiety	Stroke
Synaptic Proteins & Receptors	Vision & Sensory Systems

Adenosines	Adrenoceptors
Angiotensin Receptors	Calcium Channels
Cannaboids	Cardiovascular Peptides
Chemokines	Cytokines
Dopamine	Drug Discovery
Esterases	GABA
Gastrointestinal Peptides	Glucagon-Like Receptors
Glutamate	Gut Hormones
Histamine	Immune Receptors
Ion Channels	Ion Pumps/Transporters
Kinases	Melanocortin Receptors
Neuropeptides	Neurotransmitter Transporters
Nicotinic Receptors	NPY Receptors
Nuclear Receptors	Opioids
Orexin Receptors	Peptide Receptors
Peptides (Cardiovascular)	Peptides (Gastrointestinal)
Peptides (Neuropeptides)	Phosphodiesterases
Potassium Channels	PPAR
Protease-Activated Receptors	Purines
Retinoid X Receptors	RSTK's
Sodium Channels	Steroid Hormones
T Receptors	TRP Channels
TRPV Channels	5-HT Receptors

Aspartic Proteases & Regulators	Carbonic Anhydrases
Cyesteine Proteases & Regulators	DNA Modifying Enzymes
Glycobiology-related Enzymes	Intracellular Kinases
Lipid Metabolism Enzymes	Metalloproteases & Regulators
Methyltransferases & Demethylases	Oxidative Stress Enzymes
Phosphatases & Regulators	Receptor Tyrosine Kinases
Serine Proteases & Regulators	Sulfation Regulators

Adhesion/Cell Motility/Cytoskeleton	Apotosis/Autophagy
Cell Cycle Pathways	Heat Shock Proteins
Heterotrimeric G Protein Signaling	Jak/Stat Pathways
MAP Kinase Pathways	NFkB Pathways
p53 Pathways	PI3K/Ak/mTOR Pathways
Small G Protein Signaling	Transcription & Translation Regulation

Adult/Somatic Stem Cells	Embryonic Induced Pluripotent Stem Cells
Hematopoietic Stem Cells	Mesencvhymal Stem Cells
Neural Stem Cells

Allergy	Asthma
Cystic Fibrosis