AMP PNP

Tocris Bioscience | Catalog # 6086

Kir6 blocker; non-hydrolyzable AMP analog
Tocris Bioscience

Key Product Details

Description

Kir6 blocker; non-hydrolyzable AMP analog
View all Inward Rectifier Potassium Channel Blockers »

Product Description

AMP PNP is a non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.

Product Specifications for AMP PNP

Molecular Weight

529.93

Formula

C10H13Li4N6O12P3

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt

CAS Number

72957-42-7

PubChem ID

44134521

InChI Key

FDBDJIGGLGUOPP-UHFFFAOYSA-J

SMILES

NC1=C2C(N([C@@H]3O[C@H](COP(OP(NP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[Li+].[Li+].[Li+].[Li+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 26.5 50

Preparing Stock Solutions for AMP PNP

The following data is based on the product molecular weight 529.93.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.77 mL 18.87 mL 37.74 mL
2.5 mM 0.75 mL 3.77 mL 7.55 mL
5 mM 0.38 mL 1.89 mL 3.77 mL
25 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for AMP PNP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AMP PNP

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for AMP PNP (1)

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  • AMP PNP was used to estimate Kir blocking on Natural Killer cells.
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: NK cells
    Verified Customer | Posted 01/16/2019
    AMP PNP was used to estimate Kir blocking on Natural Killer cells at increasing concentrations.
    AMP PNP 6086

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