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BAY 805

Catalog #: 7984 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7984/50
7984/10
BAY 805 | CAS No. 2925481-88-3 | Deubiquitinating Enzyme Inhibitors
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Description: Potent and selective inhibitor of USP21; also NF-κB activator

Chemical Name: N-[(1R)-1-[[[5-[(4-Cyanophenyl)methyl]-1,3,4-thiadiazol-2-yl]amino]carbonyl]-3-methylbutyl]-1-(trifluoromethyl)cyclohexanecarboxamide

Purity: ≥98%

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Biological Activity

BAY 805 is a potent and selective inhibitor of USP21 (IC50 = 6 nM, Kd = 2.2 nM). BAY 805 induces NF-κB activation (EC50= 17 nM in a cell-based reporter assay).

Technical Data

M.Wt:
507.58
Formula:
C24H28F3N5O2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2925481-88-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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