Home / Proteasome Inhibitors / Boston Biochem Z-Leu-Leu-Leu-CHO (MG-132)

Boston Biochem Z-Leu-Leu-Leu-CHO (MG-132)

Catalog #: I-130
20 Citations Datasheet / COA / SDS
Newer Version Available: 1748
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Proteasome and calpain inhibitor. Inhibits NF-kappaB activation

Discontinued Product

I-130 has been discontinued and is replaced by 1748.

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Citations (20)
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Boston Biochem Z-Leu-Leu-Leu-CHO (MG-132) Summary

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Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-Species

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Citations for Boston Biochem Z-Leu-Leu-Leu-CHO (MG-132)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

20 Citations: Showing 1 - 10
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  1. Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis
    Authors: Zhou, YX;Wei, J;Deng, G;Hu, A;Sun, PY;Zhao, X;Song, BL;Luo, J;
    Nature cell biology  2023-06-05
  2. Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion
    Authors: JQ Wang, LL Li, A Hu, G Deng, J Wei, YF Li, YB Liu, XY Lu, ZP Qiu, XJ Shi, X Zhao, J Luo, BL Song
    Nature, 2022-08-03;608(7922):413-420.  2022-08-03
  3. A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery
    Authors: HWS Tan, G Lu, H Dong, YL Cho, A Natalia, L Wang, C Chan, D Kappei, R Taneja, SC Ling, H Shao, SY Tsai, WX Ding, HM Shen
    Nature Communications, 2022-06-28;13(1):3720.  2022-06-28
  4. WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP
    Authors: G Lu, HWS Tan, T Schmauck-M, L Wang, J Chen, YL Cho, K Chen, JZ Zhang, W He, Y Wu, D Xia, J Zhou, EF Fang, L Fang, W Liu, HM Shen
    Autophagy, 2022-04-07;0(0):1-15.  2022-04-07
  5. Fam72a enforces error-prone DNA repair during antibody diversification
    Authors: M Rogier, J Moritz, I Robert, C Lescale, V Heyer, A Abello, O Martin, K Capitani, M Thomas, AS Thomas-Cla, B Laffleur, F Jouan, E Pinaud, K Tarte, M Cogné, SG Conticello, E Soutoglou, L Deriano, B Reina-San-
    Nature, 2021-11-24;0(0):.  2021-11-24
  6. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
    Authors: C Shen, A Nayak, LR Neitzel, AA Adams, M Silver-Ise, LM Sawyer, H Benchabane, H Wang, N Bunnag, B Li, DT Wynn, F Yang, M Garcia-Con, CH Williams, S Dakshanamu, CC Hong, NG Ayad, AJ Capobianco, Y Ahmed, E Lee, DJ Robbins
    Nature Communications, 2021-09-06;12(1):5263.  2021-09-06
  7. Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation
    Authors: E Turco, A Savova, F Gere, L Ferrari, J Romanov, M Schuschnig, S Martens
    Nature Communications, 2021-09-01;12(1):5212.  2021-09-01
  8. STAT3 Stabilizes IKK&alpha Protein through Direct Interaction in Transformed and Cancerous Human Breast Epithelial Cells
    Authors: YI Hahn, S Saeidi, SJ Kim, SY Park, NY Song, J Zheng, DH Kim, HB Lee, W Han, DY Noh, HK Na, YJ Surh
    Cancers, 2020-12-30;13(1):.  2020-12-30
  9. Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies
    Authors: Z Sha, T Blyszcz, R González-P, ACO Vertegaal, AL Goldberg
    J. Biol. Chem., 2019-07-08;0(0):.  2019-07-08
  10. TRIM24 mediates the interaction of the retinoic acid receptor alpha with the proteasome
    Authors: M Carrier, R Lutzing, S Gaouar, C Rochette-E
    FEBS Lett., 2018-03-30;0(0):.  2018-03-30
  11. Mouse Mammary Tumor Virus Signal Peptide Uses a Novel p97-Dependent and Derlin-Independent Retrotranslocation Mechanism To Escape Proteasomal Degradation
    Authors: H Byun, P Das, H Yu, A Aleman, MM Lozano, A Matouschek, JP Dudley
    MBio, 2017-03-28;8(2):.  2017-03-28
  12. Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution
    Authors: Ekta Tripathi
    EMBO J, 2016-12-19;0(0):.  2016-12-19
  13. The Itch ubiquitin ligase is required for KSHV RTA induced vFLIP degradation
    Authors: Jennifer C Chmura
    Virology, 2016-11-30;501(0):119-126.  2016-11-30
  14. The Proteasome Subunit Rpn8 Interacts with the snoRNP Assembly Protein Pih1 and Mediates its Ubiquitin-Independent Degradation in Saccharomyces cerevisiae
    Authors: A Paci, XH Liu, L Zhang, R Zhao
    J Biol Chem, 2016-04-06;0(0):.  2016-04-06
  15. The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.
    Authors: Schumacher, Marc M, Elsabrouty, Rania, Seemann, Joachim, Jo, Youngah, DeBose-Boyd, Russell
    Elife, 2015-03-05;4(0):.  2015-03-05
  16. Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells.
    Authors: Dasgupta S, Castro L, Dulman R, Yang C, Schmidt M, Ferro E, Fricker L
    PLoS ONE, 2014-07-31;9(7):e103604.  2014-07-31
  17. CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.
    Authors: Shibata E, Dar A, Dutta A
    J Biol Chem, 2014-06-24;289(33):23056-64.  2014-06-24
  18. Nitric oxide and interleukin-1beta stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes.
    Authors: Lee C, Lee B, Arnold S, Isoherranen N, Morgan E
    J Pharmacol Exp Ther, 2013-10-21;348(1):141-52.  2013-10-21
  19. Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination.
    Authors: Xu, Xinsong, Keshwani, Malik, Meyer, Kathleen, Sarikas, Antonio, Taylor, Susan, Pan, Zhen-Qia
    J Biol Chem, 2012-10-08;287(48):40758-66.  2012-10-08
  20. Skp1-Cul1-F-box ubiquitin ligase (SCF(betaTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry.
    Authors: Burrows A, Prokop J, Summers M
    J Biol Chem, 2012-10-01;287(46):39021-9.  2012-10-01

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