CART (55-102) (rat)
Purity: ≥95%
Biological Activity
CART (55-102) (rat) is a cocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response. Induces anxiety and stress behavior in rodents.Technical Data
(Modifications: Disulfide bridges: 14-32, 20-40, 34-47)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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CART, a new anorectic peptide.
Thim et al.
Int.J.Biochem.Cell Biol., 1998;30:1281 -
Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold.
Ludvigsen et al.
Biochemistry, 2001;40:9082 -
Cocaine- and amphetamine-regulated transcript peptide produces anxiety-like behavior in rodents.
Chaki et al.
Eur.J.Pharmacol., 2003;464:49
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Citation for CART (55-102) (rat)
The citations listed below are publications that use Tocris products. Selected citations for CART (55-102) (rat) include:
1 Citation: Showing 1 - 1
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Traumatic stress affects alcohol-drinking behavior through cocaine- and amphetamine-regulated transcript 55-102 in the paraventricular nucleus in rats
Authors: Liu Et al.
Mol.Med.Rep. 2018;17:1157
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