CGRP 8-37 (human)

Name: CGRP 8-37 (human)
Brand: Tocris Bioscience
SKU: 1181
Price: 437 USD
Availability: InStock

Tocris Bioscience | Catalog # 1181

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Citations (3)

Product Documents

CGRP antagonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

CGRP antagonist

Alternative Names

Calcitonin Gene-Related Peptide 8-37 (human)

View all Calcitonin and Related Receptor Antagonists »

Product Description

CGRP 8-37 (human) is a peptide antagonist for CGRP₁ receptors.

Product Specifications for CGRP 8-37 (human)

Molecular Weight

3125.64

Formula

C₁₃₉H₂₃₀N₄₄O₃₈

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

119911-68-1

PubChem ID

16134896

InChI Key

NDACAFBDTQIYCQ-YVQXRMNASA-N

SMILES

[H]N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.5mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Wisskirchen Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. 1998 PMID: 9605575
Poyner Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 1995 PMID: 8578616
Poyner Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. Br.J.Pharmacol. 1998 PMID: 9756381
Nakamura Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 1998 PMID: 9757038

Product Documents for CGRP 8-37 (human)

Download SDS

Product Specific Notices for CGRP 8-37 (human)

For research use only

Related Research Areas

Metabolic Peptide Hormones and Regulators

Osteoblast and Osteoclast Markers

Citations for CGRP 8-37 (human)

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