Chlormethiazole hydrochloride

Key Product Details

Product Description

Chlormethiazole hydrochloride is a sedative and anticonvulsant which is neuroprotective in a number of animal models. Prevents the degeneration of serotonergic nerve terminals induced by MDMA ('Ecstasy').

Product Specifications for Chlormethiazole hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Chlormethiazole hydrochloride

The following data is based on the product molecular weight 198.11.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.05 mL	25.24 mL	50.48 mL
5 mM	1.01 mL	5.05 mL	10.10 mL
10 mM	0.50 mL	2.52 mL	5.05 mL
50 mM	0.10 mL	0.50 mL	1.01 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Hewitt and Green Chloromethiazole, dizocilpine and halope. prevent the degeneration of serotonergic nerve terminals induced by the administration of MDMA ('Ecstasy') to rats. Neuropharmacology 1994 PMID: 7539115
• Cross The protective action of chloromethiazole against ischaemia induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity. Br.J.Pharmacol. 1995 PMID: 7599932

Product Documents for Chlormethiazole hydrochloride