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CometSlide High Throughput

Catalog #: 4252-02K-01
5 Citations Datasheet / COA / SDS

Discontinued Product

4252-02K-01 has been discontinued.
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Citations (5)
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CometSlide High Throughput Summary

Sample-ready pre-treated 20-well glass slides for the rapid analysis of DNA fragmentation associated with DNA damage.

Why Use CometSlides for the CometAssay?

CometSlide High Throughput is a component of the CometAssay High Throughput Kit (R&D Systems®, Catalog # 4252-040-K) which is used for the rapid analysis of DNA fragmentation associated with DNA damage. CometSlide High Throughput is a 20-well slide that is specially treated to promote agarose adherence and easy application of cells directly to each well. This slide provides a convenient, simple, and reliable format for sample preparation, processing, analysis, and storage for the CometAssay.

The CometAssay, or single cell gel electrophoresis assay, permits the quantification of DNA damage in individual cells based on the migration of DNA structures in an electric field. Evaluation of the DNA “Comet” tail shape and migration pattern allows for assessment of DNA damage, expressed as tail length, percent DNA in the tail and tail moment.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended on the label.
Storage
Store the unopened product at room temperature. Do not use past expiration date.
Species
N/A

Limitations

For research use only. Not for diagnostic use.

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Citations for CometSlide High Throughput

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients
    Authors: DT Stefanou, M Kouvela, D Stellas, K Voutetakis, O Papadodima, K Syrigos, VL Souliotis
    Biomedicines, 2022-05-26;10(6):.  2022-05-26
  2. CpG site-specific methylation as epi-biomarkers for the prediction of health risk in PAHs-exposed populations
    Authors: L Ye, Z He, D Li, L Chen, S Chen, P Guo, D Yu, L Ma, Y Niu, H Duan, X Xing, Y Xiao, X Zeng, Q Wang, G Dong, M Aschner, Y Zheng, W Chen
    Journal of Hazardous Materials, 2022-02-22;431(0):128538.  2022-02-22
  3. Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus
    Authors: I Rashid, M Hammel, A Sverzhinsk, MS Tsai, JM Pascal, JA Tainer, AE Tomkinson
    The Journal of Biological Chemistry, 2021-06-25;0(0):100921.  2021-06-25
  4. The Effects of Muscle Cell Aging on Myogenesis
    Authors: A Moustogian, A Philippou, O Taso, E Zevolis, M Pappa, A Chatzigeor, M Koutsilier
    International Journal of Molecular Sciences, 2021-04-02;22(7):.  2021-04-02
  5. Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China
    Authors: S Chen, D Li, X Wu, L Chen, B Zhang, Y Tan, D Yu, Y Niu, H Duan, Q Li, R Chen, M Aschner, Y Zheng, W Chen
    Environ Int, 2020-04-04;139(0):105703.  2020-04-04

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